Incruse Ellipta vs. Spiriva: Umahluko, ukufana, kwaye kukuphi okungcono kuwe
Iziyobisi Vs. UmhloboUkujonga ngokubanzi iziyobisi kunye nolwahluko ophambili | Imiqathango iphathwe | Ukusebenza | Ukuhlawulwa kwe-inshurensi kunye nokuthelekiswa kweendleko | Imiphumela | Ukusebenzisana kweziyobisi | Izilumkiso | FAQ
Ngokwe- Umbutho waseMelika wemiphunga , Isifo esinganyangekiyo semiphunga, okanye i-COPD, sesona sizathu siphambili sokufa sisifo e-U.S. ngaphezulu kwezigidi ezili-16 zabantu kuye kwafunyaniswa ukuba bane-COPD, nezigidi zichaphazeleka kakhulu kodwa abakazi. I-COPD sisifo esingapheliyo sokudumba kwemiphunga. Izigulana ezine-COPD zihlala zifumana ubunzima bokuphefumla, ukukhohlela, ukuvutha, kunye nemveliso ye-mucus. I-COPD ibandakanya i-emphysema kunye ne-bronchitis engapheliyo. Amayeza amabini aqhelekileyo asetyenziselwa ukulawula i-COPD ngamayeza anyangwa ngomlomo abizwa ngokuba yi-Incruse Ellipta kunye neSpiriva.
Incruse Ellipta kunye neSpiriva omabini la magama anegama lebrendi abonisiweyo kunyango lwexesha elide ICOPD . Omabini la machiza avunyiwe yi-U.S. Bahlelwa kwiqela lamayeza abizwa ngokuba yi-anticholinergics. Zisebenza ngokuphucula izihlunu emiphungeni, zenze ukuba kube lula ukuphefumla.
Nangona i-Incruse Ellipta kunye neSpiriva zombini ziyi-anticholinergics ezisetyenziselwa i-COPD, azifani ncam. Qhubeka nokufunda apha ngezantsi ukuze ufunde ngakumbi ngeyeza ngalinye.
Nguwuphi umahluko ophambili phakathi kwe-Incruse Ellipta kunye neSpiriva?
Incruse Ellipta kunye neSpiriva zombini amayeza anticholinergic, afumaneka ngegama lebrand kuphela. Bakwaziwa njengabasebenza ixesha elide be-muscarinic antagonists (LAMA).
Igama leekhemikhali le-Incruse Ellipta ngu-umeclidinium. Itholakala kwifom ye-inhaler kuphela. IGlaxoSmithKline (GSK) yenza i-Incruse Ellipta.
Igama lekhemikhali leSpiriva yi-tiotropium bromide. Iyafumaneka zombini njenge-capsule yomlomo (ye-inhalation yomlomo, ingaginywa-ikwabizwa ngokuba yi-powder eyomileyo inhaler) kunye nenkungu yomlomo yokuphefumla. I-Boehringer Ingelheim Pharmaceuticals yenza iSpiriva.
| Umahluko ophambili phakathi kwe-Incruse Ellipta kunye neSpiriva | ||
|---|---|---|
| Fakela uEllipta | Spiriva | |
| Iklasi yeziyobisi | I-Anticholinergic | I-Anticholinergic |
| Uhlobo lweBrith / generic | Igama lebrand | Igama lebrand |
| Ngubani igama eliqhelekileyo? | Umeclidinium | I-Tiotropium bromide |
| Zeziphi iifom eza nalo iziyobisi? | Faka i-Ellipta Inhaler (inhalation powder) | I-Spiriva Handihaler (iifomsile ze-inhalation), i-Spiriva Respimat (inkungu yokuphefumula) |
| Ithini idosi esemgangathweni? | Inhalation yomlomo omnye (62.5 mcg) kanye yonke imihla ngexesha elifanayo yonke imihla | I-Spiriva Handihaler: I-inhalations yomlomo yomxholo we-Spiriva capsule (i-18 mcg) kanye yonke imihla, kunye nesixhobo se-Handihaler (ii-capsules zenzelwe ukuphefumula ngomlomo kuphela; akufuneki kuginywe) I-Spiriva Respimat: 2 inhalations yomlomo (ye-1.25 mcg okanye i-2.5 mcg) kanye yonke imihla |
| Lude kangakanani unyango oluqhelekileyo? | Ixesha elide | Ixesha elide |
| Ngubani oqhelekileyo usebenzisa amayeza? | Abantu abadala | Handihaler: Abantu abadala Impendulo: Abantu abadala nabantwana abaneminyaka emithandathu nangaphezulu |
Imiqathango iphathwe ngu-Incruse Ellipta noSpiriva
Incruse Ellipta kunye neSpiriva kubonisiwe kunyango lokugcina isifo esinganyangekiyo semiphunga (COPD). Ngokukodwa, ulwazi lomenzi weSpiriva Handihaler luchaza ukuba lisetyenziselwa ukunciphisa ukuqaqanjelwa kwizigulana zeCOPD.
I-Spiriva Respimat inesinye isibonakaliso esongezelelweyo-unyango lokunyanga i-asthma kwizigulana ezineminyaka emi-6 nangaphezulu.
Akukho siyobisi sisetyenziselwa uhlaselo olubi.
| Imeko | Fakela uEllipta | Spiriva |
| Unyango lolondolozo lweCOPD | Ewe | Ewe (Handihaler kunye neempendulo) |
| Ukugcina unyango lwe-asthma kwizigulana ezineminyaka emithandathu nangaphezulu | Hayi | Ewe (Phendula) |
Ngaba i-Incruse Ellipta okanye iSpiriva isebenza ngakumbi?
Kukho idatha encinci ethelekisa la machiza mabini ngokuthe ngqo. A Isifundo seeveki ezili-12 Thelekisa ukusebenza kunye nokhuseleko lwe-Incruse Ellipta kunye neSpiriva kwizigulana ezingaphezu kwe-1 000 ezineCOPD. Indawo yokugqibela yayikumthamo wokunyanzelwa kwevolumu yokuphefumla ngomzuzwana omnye (okwabizwa ngokuba yi-FEV1) ngosuku lwe-85. Izigulana zavavanywa kusetyenziswa iphepha lemibuzo laseSt George's Respiratory Questionnaire nolunye uvavanyo. Omabini la machiza abonise ukuphucuka okunentsingiselo kubomi babo kwaye ayanyamezeleka malunga nokhuseleko. Uphononongo luqukumbele i-Incruse Ellipta ukuba isebenze ngakumbi kuneSpiriva.
Ngumboneleli wakho wezempilo kuphela onokumisela elona nyango lisebenzayo kuwe. Unokujonga ubunzima beempawu zakho kunye nembali yakho yezonyango, kunye namanye amayeza owathathayo anokuthi asebenzisane ne-Incruse Ellipta okanye Spiriva.
Umyinge kunye nokuthelekiswa kweendleko ze-Incruse Ellipta vs. Spiriva
Izicwangciso ze-inshurensi kunye ne-Medicare Icandelo D zigubungela zombini i-Incruse Ellipta kunye neSpiriva, kodwa imali yokugubungela iyahluka ngokwesicwangciso.
Ixabiso eliphuma epokothweni le-Incruse Ellipta inhaler limalunga ne- $ 477, kodwa ungasebenzisa ikhadi le-SingleCare ukunciphisa ixabiso ukuya kuthi ga kwi-306 yeedola.
Ixabiso elingaphandle kwepokotho le-Spiriva Handihaler limalunga ne- $ 634, kwaye i-Spiriva Respimat imalunga ne- $ 600. Sebenzisa isigqebhezana se-SingleCare kuya kuthoba amaxabiso ukuya kuthi ga kwi-404 yeedola kwiHandihaler okanye kwi-Respimat.
| Fakela uEllipta | Spiriva | |
| Ngokuqhelekileyo i-inshurensi? | Ewe | Ewe |
| Ngokuqhelekileyo ihlanganiswe yiCandelo le-Medicare? | Ewe | Ewe |
| Umthamo osemgangathweni | 1 inhaler | 1 Handihaler okanye 1 Respimat |
| I-Medicare copay eqhelekileyo | $ 8- $ 395 | I $ 3- $ 524 |
| Ixabiso elilodwa | $ 306 + | $ 404 + |
Iziphumo eziqhelekileyo ezichaphazelekayo ze-Incruse Ellipta vs. Spiriva
Iziphumo eziqhelekileyo ezichaphazelekayo ze-Incruse Ellipta zi-nasopharyngitis (ukubanda okuqhelekileyo), ukusuleleka kwintsholongwane yokuphefumula kunye nokukhwehlela.
Iziphumo eziqhelekileyo ezichaphazelekayo ze-Spiriva zintsholongwane ephezulu yokuphefumula, i-sinusitis, intlungu yesifuba, umlomo owomileyo, ukuqunjelwa, kunye nokusuleleka kwintsholongwane.
Olu aluluhlu olupheleleyo lweziphumo ebezingalindelekanga. Ezinye iziphumo ezibi zinokwenzeka. Nxibelelana nomboneleli wakho wezempilo ukuze ufumane uluhlu olupheleleyo lweziphumo ebezingalindelekanga ze-Incruse Ellipta kunye neSpiriva.
| Fakela uEllipta | Spiriva | |||
| Imiphumela | Iyasebenza? | Rhoqo | Iyasebenza? | Rhoqo |
| I-Nasopharyngitis / ipharyngitis | Ewe | 8% | Ewe | 9% |
| Usulelo oluphezulu lokuphefumula | Ewe | 5% | Ewe | 41% |
| Khohlela | Ewe | 3% | Ewe | > 3% |
| Iintlungu zesifuba | Hayi | - | Ewe | 7% |
| Umlomo owomileyo | Hayi | - | Ewe | 16% |
| Ukuqunjelwa | Hayi | - | Ewe | 4% |
| Ukuhlanza | Hayi | - | Ewe | 4% |
| Isinusitis | Ewe | Akuxelwanga | Ewe | Shumi elinanye% |
| Irhashalala | Ewe | Akuxelwanga | Ewe | 4% |
| IArthralgia (iintlungu ezidibeneyo) | Ewe | Mbini% | Ewe | 4.2% |
| Usulelo lwe-Urinary tract | Ewe | Akuxelwanga | Ewe | 7% |
Umthombo: DailyMed ( Fakela uEllipta ), Yonke imihla ( Spiriva )
Ukudibana kweziyobisi kwi-Incruse Ellipta vs. Spiriva
Ngenxa yokuba i-Incruse Ellipta kunye ne-Spiriva ngamayeza e-anticholinergic, akufuneki asetyenziswe namanye amayeza e-anticholinergic. Indibaniselwano inokubangela ukwanda kweziphumo ebezingalindelekanga, njengokugcina umchamo okanye i-glaucoma emxinwa.
Olunye unxibelelwano lweziyobisi lunokwenzeka. Nxibelelana nomboneleli wakho wezempilo uluhlu olupheleleyo lokudibana kwamachiza.
| Iziyobisi | Iklasi yeziyobisi | Fakela uEllipta | Spiriva |
| Belladonna alkaloids I-Benztropine Clidinium I-Darifenacin Dicclomine Idiphenhydramine IHyoscyamine Ipropropium Orphenadrine Oxybutynin I-Scopolamine Solifenacin Itolterodine Imvelaphi yecyphenidyl | I-Anticholinergics | Ewe | Ewe |
Izilumkiso ze-Incruse Ellipta kunye neSpiriva
- Sukusebenzisa i-Incruse Ellipta okanye iSpiriva ukuba une-hypersensitivity eqatha kwiiprotein zobisi okanye nasiphi na isithako.
- I-Incruse Ellipta okanye i-Spiriva ayenzelwanga ukuba isetyenziselwe ukwehla ngokukhawuleza okanye iicOPD ezisongela ubomi. La machiza khange afundwe kwiziqendu ezibi kwaye akufuneki asetyenziswe ukunciphisa iimpawu ezibi. Musa ukuthatha iidosi ezongezelelweyo ukukhululeka kweempawu ezibi. Umboneleli wakho wokhathalelo lwempilo kufuneka akunike imiyalelo ekulawuleni isiqendu esibukhali-uya kuthi usebenzise i-inhaler eyahlukileyo, esebenza ngokufutshane njenge-inhaler yokuhlangula.
- I-Incruse Ellipta okanye i-Spiriva inokubangela ukuba i-bronchospasm engathandabuzekiyo ebomini (ukuwohloka kokuphefumla okanye ukuvutha), ekufuneka iphathwe kwangoko nge-bronchodilator inhaler emfutshane. Ukuba oku kuyenzeka, yeka ukufaka i-Ellipta okanye iSpiriva kwangoko. Umboneleli wakho wezempilo unokuyalela olunye unyango.
- I-Incruse Ellipta okanye i-Spiriva inokubangela ukusabela kwe-hypersensitivity, kubandakanya i-anaphylaxis, i-angioedema, ukurhawuzelela, okanye irhashalala. Yeka i-Incruse Ellipta okanye i-Spiriva kwaye uqhagamshelane nomboneleli wakho wezempilo ukuba kukho naziphi na ezi mpendulo. Ukuba unengxaki yokuphefumla okanye amava adumbileyo kwimilebe yakho, ulwimi, kunye nomlomo, funa unyango olungxamisekileyo.
- Sebenzisa i-Incruse Ellipta okanye iSpiriva ngononophelo kwizigulana ezinekona emxinwa yeglaucoma. Izigulana kunye nabacebisi bazo kufuneka bajonge iimpawu ze-glaucoma emxinwa (iintlungu zamehlo, umbono ongacacanga, iihosos ezibonakalayo). Qhagamshelana nomboneleli wakho wezempilo ngokukhawuleza ukuba kukho naziphi na kwezi mpawu.
- Sebenzisa i-Incruse Ellipta okanye iSpiriva ngononophelo kwizigulana ezinokugcinwa komchamo. Izigulana kunye nabacebisi kufuneka bazi iimpawu zokugcina umchamo, ezinjengokuchama kabuhlungu kunye nobunzima bokuchama. Qhagamshelana nomboneleli wakho wezempilo ngokukhawuleza ukuba ufumana ezi mpawu.
Spiriva kuphela:
- Ukubeka iliso kwizigulana ezinomodareyitha wokukhubazeka kwezintso kwiziphumo ze-anticholinergic.
- Iicapsules zezokuphefumla ngomlomo kuphela kwaye akufuneki ziginywe. Sebenzisa iifomsile kuphela ngesixhobo seHandihaler.
Imibuzo ebuzwa rhoqo malunga ne-Incruse Ellipta vs. Spiriva
Yintoni i-Incruse Ellipta?
Incruse Ellipta lunyango lwe-anticholinergic esetyenziselwa i-COPD. Kuyanceda ukukhulula imiphunga, ukwenza ukuphefumla kube lula.
Yintoni i-Spiriva?
I-Spiriva ikwayiyeza elichasene ne-anticholinergic elisetyenziselwa i-COPD. Iyafumaneka njenge-capsule ephefumlelweyo kunye nenkungu yokuphefumla.
Ngaba i-Incruse Ellipta kunye neSpiriva ziyafana?
Omabini la mayeza ayafana kwaye akwicandelo elinye leziyobisi. Nangona kunjalo, banomahluko, njengeziphumo ebezingalindelekanga kunye nedosi, echazwe apha ngasentla.
Ngaba i-Incruse Ellipta okanye iSpiriva ingcono?
Idatha emiselweyo iyafumaneka ngokuthelekisa i-Incruse Ellipta ukuya eSpiriva. Olunye uphononongo lubonise i-Incruse Ellipta ukuba isebenze ngakumbi, kodwa omabini amayeza ukuba akhuseleke ngokulinganayo. Umboneleli wakho wezempilo unokumisela ukuba leliphi iyeza elilunge ngakumbi kuwe.
Ndingayisebenzisa i-Incruse Ellipta okanye iSpiriva ngelixa ndikhulelwe?
Akukho lwazi lwaneleyo kwiziphumo ze-Incruse Ellipta okanye iSpiriva ekukhulelweni. Nxibelelana ne-OB-GYN yakho malunga neengcebiso zonyango. Ukuba sele uthatha i-Incruse Ellipta okanye iSpiriva kwaye ufumanisa ukuba ukhulelwe, nxibelelana ne-OB-GYN yakho.
Ndingayisebenzisa i-Incruse Ellipta okanye iSpiriva ngotywala?
Nangona i-Incruse Ellipta okanye iSpiriva ingadibani notywala, ukusela utywala ixesha elide kunokunyusa iimpawu zeCOPD kunye nokwenza buthathaka amajoni akho omzimba, ukuqaqambisa iimpawu zakho zeCOPD. Nxibelelana nomboneleli wakho wezempilo ngolwazi oluthe kratya malunga notywala kunye neCOPD.
Ngaba i-Incruse Ellipta yi-steroid?
Incruse Ellipta ayisiyo steroid. Ihlelwa njengeyeza elichasene ne-anticholinergic. Ihlaziya izihlunu zomoya ukwenza ukuphefumla kube lula.
Ezinye i-inhalers ziqukethe i-corticosteroid ekhutshiweyo kwaye zisetyenziselwa ukunyanga i-COPD. I-Advair iqulethe i-fluticasone (i-steroid) kunye ne-salmeterol (i-beta-agonist esebenza ixesha elide). Omnye umzekelo nguBreo Ellipta, oqukethe i-fluticasone furoate (i-steroid) kunye ne-vilanterol (i-beta-agonist esebenza ixesha elide).
Yiyiphi inhaler elingana neSpiriva?
Ezinye i-inhalers ezikudidi olunye lweSpiriva kunye ne-Incruse Ellipta zibandakanya iTudorza Pressair (aclidinium) kunye neSeebri Neohaler (glycopyrrolate).
Yeyiphi eyona inhaler ilungileyo yeCOPD?
Lowo ngumbuzo onzima. Kuxhomekeka kwizinto ezimbalwa, njengobukhali kunye nohlobo lweempawu, imbali yakho yezonyango, kunye namanye amayeza owathathayo. Umboneleli wakho wezempilo unokumisela ukuba yeyiphi i-inhaler ekulungeleyo.
Zininzi iyeza lokurhola ngaphakathi kwimarike. Nazi iindlela ezimbalwa zonyango ezichazwe kwi-COPD:
I-SABA (i-bronchodilators emfutshane, okanye i-beta-agonists). IAlbuterol HFA, iProair HFA, iProventil HFA, iVentolin HFA, iXopenex
Ii-LABAs (i-beta2 agonists esebenza ixesha elide): IBrovana (arformoterol), iSerevent (salmeterol)
I-LAMAs (abasebenza ixesha elide abachasayo be-muscarinic): Incruse Ellipta (umeclidinium), Seebri (glycopyrrolate), Spiriva (tiotropium) Respimat okanye Handihaler, Tudorza Pressair (aclidinium)
I-LAMA + LABA indibaniselwano inhaler: Anoro Ellipta (umeclidinium / vilanterol), Bevespi Aerosphere (glycopyrrolate / formoterol), Stiolto Respimat (olodaterol / tiotropium),
Utibron Neohaler (indacaterol / glycopyrrolate)
Ukungenisa i-corticosteroids: Qvar RediHaler (beclomethasone), iPulmicort Flexhaler (budesonide)
Umdibaniso we-corticosteroid + LABA: Isimbicort (budesonide / formoterol), Advair (fluticasone / salmeterol), Breo (fluticasone / vilanterol), iDulera (mometasone / formoterol)
