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Idosi yeTadalafil, iifom, kunye namandla

Ulwazi lweziyobisi

I-Tadalafil sisiyobisi esisetyenziswa kunyango lwe-pulmonary arterial hypertension, i-erectile dysfunction (ED), okanye iimpawu ezisezantsi zomchamo wokwandiswa kweprostate (benign prostatic hyperplasia okanye i-BPH). I-Tadalafil ifumaneka kuphela njengepilisi kwaye ithathwa ngomlomo kanye ngemini kunye okanye ngaphandle kokutya. Nangona ithengiswa njengechiza eliqhelekileyo, i-tadalafil ikwafumaneka njengeziyobisi ezibizwa ngokuba zii-brand: Cialis kunye ne-Adcirca. Cialis Ithengiswa kumandla ethebhulethi afanelekileyo e-erectile dysfunction kunye ne-prostate eyandisiweyo. I-Adcirca iza ngamandla afanelekileyo ukunyanga uxinzelelo lwegazi kwimiphunga.

I-Tadalafil yeyosapho lweziyobisi ezibizwa ngokuba yi-PDE5 inhibitors, okanye i-phosphodiesterase yohlobo lwe-5 inhibitors. La machiza akhulula izihlunu ezigudileyo kwimithambo yegazi, ngakumbi imithambo, ebangela ukuba bandise. Oku kunciphisa uxinzelelo lwegazi kwimithambo ye-pulmonary, ukunciphisa uxinzelelo lwegazi, kunye nokunyusa nokunyusa ukuhamba kwegazi kwilungu lobudoda, kunceda ukuphucula ukusebenza kwamadoda ngokwesondo. I-PDE5 inhibitors zikwaphucula izihlunu kwisinyi nakwindlela esezantsi yokuchama, ukunceda ukunciphisa iimpawu zomchamo kumadoda anokwandiswa kweprotate.

Ezinxulumene: Funda ngakumbi ngeTadalafil | Fumana izaphulelo zeTadalafil

Idosi yeTadalafil, iifom, kunye namandla

I-Tadalafil ithathwa njengethebhulethi kwi amandla amane edosi eyahlukileyo .

Ithebhulethi: 2.5 milligrams (mg), 5 mg, 10 mg, kunye no-20 mg

Idosi yeTadalafil yabantu abadala

I-Tadalafil ithathwa kanye ngemini kwi-pulmonary hypertension okanye kwi-BPH. Ingathathwa yonke imihla okanye njengoko kufuneka kwi-erectile dysfunction.

Umgangatho osemgangathweni wabantu abadala: 2.5-5 mg (BPH okanye ED) okanye 40 mg (pulmonary arterial hypertension) kanye ngemini okanye nge-5-20 mg njengoko kufuneka (ED)
Elona nani liphezulu labantu abadala: Akukho ngaphezulu kwe-20 mg ngosuku (i-BPH okanye i-ED) okanye i-40 mg ngosuku (uxinzelelo lwegazi)

Umthamo weTadalafil wabantwana

I-Tadalafil ayivunywanga yi-FDA ukuba isetyenziswe kubantu abangaphantsi kweminyaka eyi-18 ubudala.

Itshathi yokulinganisa kweTadalafil
Inkcazo	Ukuqala idosi	Umthamo osemgangathweni	Ubungakanani benqanaba
Ukungasebenzi kakuhle kwe-Erectile (njengoko kufuneka)	I-10 mg ithathwe ngaphambi kokulalana	I-5-20 mg ethathwe ngaphambi kokulalana	Akukho ngaphezulu kwe-20 mg ngosuku
Ukungasebenzi kakuhle kwe-erectile (kube kanye yonke imihla)	2.5 mg kanye ngemini	2.5-5 mg kanye ngemini	5 mg kanye ngemini
I-Benign prostatic hyperplasia kunye okanye ngaphandle kokungasebenzi kakuhle kwe-erectile	5 mg kanye ngemini	5 mg kanye ngemini	Ayichazwanga ngqo
Uxinzelelo lwegazi lwe-pulmonary arterial	40 mg kanye ngemini	40 mg kanye ngemini	Ayichazwanga ngqo

Imilinganiselo efunekayo yokungasebenzi kakuhle kwe-erectile

Njengonyango lokungasebenzi kakuhle kwe-erectile, i-tadalafil inokuthathwa njengoko ifunekayo ukuphucula ukusebenza ngokwesondo. Imigqaliselo iya kuza nge-5 mg, 10 mg, kunye namandla e-20 mg. Idosi yokuqala iqalwa nge-10 mg, kodwa le dose inokuncitshiswa ibe yi-5 mg okanye inyuswe iye kuthi ga kwi-20 mg ngokuxhomekeke ekusebenzeni nasekunyamezelweni kwethamo lokuqala.

Abantu abadala (abaneminyaka eli-18 nangaphezulu): I-5-20 mg ethathwe ngaphambi kokulindeleka kwesondo
Izigulana ezinengxaki yokugula (isifo sezintso) -ulungiso lweedosi :
- Ukucoca i-creatinine ye-30-50 milliliters (ml) / min: 5-10 mg kanye ngemini ukuya kuthi ga kwi-10 mg ubuninzi beeyure ezingama-48
- Ukucoca i-creatinine ngaphantsi kwe-30 ml / min: 5 mg qho kwiiyure ezingama-72
- I-Hemodialysis: 5 mg qho kwiiyure ezingama-72, akukho songezelelo emva kwedialysis
- I-Peritoneal dialysis: Ayichazwanga
Izigulana ezingaboni kakuhle (isifo sesibindi) -ulungiso lweedosi :
- Ukuthothisa okuphakathi ukuya kumodareyitha: Sebenzisa ngononophelo; I-5-10 mg ukuya kuthi ga kwi-10 mg ubuninzi beeyure ezingama-24
- Ukuphazamiseka okukhulu kwesibindi: Ayikhuthazwa

Idosi yemihla ngemihla yokungasebenzi kakuhle kwe-erectile

Ngenye indlela, i-tadalafil inokuthathwa mihla le kwidosi ephantsi ukunyanga ukungasebenzi kakuhle kwe-erectile. Umsebenzi wesondo unokuzibandakanya nangaliphi na ixesha phakathi kweedosi.

Abantu abadala (abaneminyaka eli-18 nangaphezulu): 2.5-5 mg ithathwa kanye ngemini
Izigulana ezinengxaki yokugula (isifo sezintso) :
- Ukucoca i-Creatinine ngaphantsi kwe-30 ml / min: Akucetyiswa
- IHemodialysis: ayikhuthazwa
- I-Peritonealdialysis: Ayichazwanga
Izigulana ezingakhubazekanga kakuhle (isifo sesibindi) :
- Ukuthothisa okuphakathi ukuya kumodareyitha: Sebenzisa ngononophelo
- Ukuphazamiseka okukhulu kwesibindi: Ayikhuthazwa

Umyinge weempawu ze-benign prostatic hyperplasia (BPH)

I-Tadalafil imiselwe njengedosi yemihla ngemihla yokunciphisa iimpawu zomchamo ezisezantsi ngenxa ye-benign prostatic hyperplasia, ehlala idityaniswa namanye amachiza afana ne-finasteride. Ukungasebenzi kakuhle kwe-erectile kungafunyanwa nangamadoda aneeprostate ezandisiweyo, ke idosi ye-tadalafil yemihla ngemihla inokunyanga zombini ezi meko.

Abantu abadala (abaneminyaka eli-18 nangaphezulu): 5 mg ithathwa kanye ngemini
Izigulana ezinengxaki yokugula (isifo sezintso) -ulungiso lweedosi :
- Ukucoca i-creatinine ye-30-50 ml / min: 2.5-5 mg kanye ngosuku
- Ukucoca i-Creatinine ngaphantsi kwe-30 ml / min: Akucetyiswa
- IHemodialysis: ayikhuthazwa
- I-Peritonealdialysis: Ayichazwanga
Izigulana ezingakhubazekanga kakuhle (isifo sesibindi) :
- Ukuthothisa okuphakathi ukuya kumodareyitha: Sebenzisa ngononophelo
- Ukuphazamiseka okukhulu kwesibindi: Ayikhuthazwa

Umyinge we-pulmonary arterial hypertension

I-Tadalafil isetyenziselwa ukuphucula ukubanakho kokuzilolonga kubantu abane-pulmonary arterial hypertension. Idosi, nangona kunjalo, iphezulu kunokuba inezinye izikhombisi: 40 mg kanye ngemini. Abantu abane-pulmonary hypertension, emva koko, baya kufumana imigqaliselo ye-20 mg tadalafil yeepilisi ezichazwe ngokukodwa kwi-pulmonary hypertension.

Abantu abadala (abaneminyaka eli-18 nangaphezulu): 40 mg ithathwa kanye ngemini
Izigulana ezinengxaki yokugula (isifo sezintso) -ulungiso lweedosi :
- Ukucoca i-creatinine ye-30-50 ml / min: 20-40 mg kanye ngemini
- Ukucoca i-Creatinine ngaphantsi kwe-30 ml / min: kuthintele ukusetyenziswa
- IHemodialysis: Kulumkele ukusebenzisa
- I-Peritoneal dialysis: Ayichazwanga
Izigulana ezingakhubazekanga kakuhle (isifo sesibindi) :
- Ukuthothisa okuphakathi ukuya kumodareyitha: Sebenzisa ngononophelo; Cinga ukuqala ngeedosi ezingama-20 mg kanye ngemini
- Ukuphazamiseka okukhulu kwesibindi: Kuphephe ukusebenzisa

Umthamo weTadalafil kwizilwanyana zasekhaya

I-FDA ayamkelanga tadalafil yokusetyenziswa kwizilwanyana. Abanye oogqirha bezilwanyana, nangona kunjalo, banokumisela i-tadalafil kwizinja kwi-pulmonary hypertension. Uphando, nangona kunjalo, isikelwe umda . Ngesi sizathu, akukho milinganiselo ichanekileyo yezilwanyana ichaziweyo, ke amagqirha ngamanye anokuyalela iidosi ezahlukeneyo ngokusekwe kumava abo. Musa, nangona kunjalo, unike i-tadalafil okanye naliphi na ichiza lomntu elimiselweyo kwisilwanyana sasekhaya ngaphandle kolawulo lwezilwanyana. Idosi inokuba iphosakele, kwaye enye okanye ezingaphezulu zezithako ezingasebenziyo zinokuba yingozi kwizilwanyana.

Uyithatha njani i-tadalafil

I-Tadalafil ithathwa ngomlomo njengepilisi okanye ngaphandle kokutya. Iya kumiselwa nokuba ibe yidosi kanye yemihla ngemihla okanye ngokweemfuno ezifunekayo.

Thatha kuphela i-tadalafil ngomyalelo kagqirha naphantsi konakekelo lomboneleli wezempilo. Thatha amayeza njengoko kuyalelwe ngumboneleli wezempilo.
Gwinya ipilisi yonke. Musa ukuyityumza okanye ukuyihlafuna.
Musa ukuthatha ngaphezulu kwedosi enye ngosuku okanye ukwahlula idosi kwiidosi ezimbini zemihla ngemihla.
Ukusetyenziswa kwansuku zonke, i-tadalafil dose kufuneka ithathwe ngexesha elifanayo ngosuku ngalunye.
Funda ngononophelo kwaye ulandele incwadana yolwazi yesigulana eza nonyango.
Ukungasebenzi kakuhle kwe-erectile, isenzo sesondo sinokuqalwa nangaliphi na ixesha ukusuka Imizuzu engama-30 ukuya kwiiyure ezingama-36 emva kokuthatha i-tadalafil.
Ukungasebenzi kakuhle kwe-erectile, ukhuthazo ngokwesondo luyafuneka kulwakhiwo.
Ukusela utywala ngaphakathi kweeyure ezingama-36 zedosi ye-tadalafil kunokunciphisa uxinzelelo lwegazi, ngenxa yoko ukusetyenziswa kotywala kulunge kakhulu.
Ukuba kuthathwe i-tadalafil eninzi, khangela ingcebiso yezonyango kwangoko.
Soloko ujonga umhla wokuphelelwa. Ukuba ixesha lokuphelelwa lixesha lidlulile, lahla ngendlela ekhuselekileyo amayeza kwaye ufumane amayeza amatsha.
I-Tadalafil kufuneka igcinwe kubushushu begumbi. Jonga incwadana yolwazi ngesigulana uluhlu lwamaqondo obushushu afanelekileyo.

Tadalafil idosi FAQs

Ithatha ixesha elingakanani ukusebenza nge-tadalafil?

Xa ithathwa ngomlomo, i-tadalafil ngokukhawuleza ingena kwigazi kwaye Uxinzelelo oluphezulu egazini kwisithuba semizuzu engama-30 ukuya kwiiyure ezintandathu. Ukufumaneka kwayo kokusebenza kunye nokusebenza kwangoko akuchaphazeleka kukutya.

Ihlala ixesha elingakanani i-tadalafil kwinkqubo yakho?

I-Tadalafil ihlala ixesha elide emzimbeni. Kunye ubomi besiqingatha yeeyure eziyi-17.5 zabantu abasempilweni ukuya kuthi ga kwiiyure ezingama-35 kubantu abane-pulmonary hypertension, idosi enye ye-tadalafil inokuthatha iintsuku ezine okanye nangaphezulu ukucoca ngaphandle komzimba. Kungenxa yoko le nto i-tadalafil ihlala ibizwa ngegama ipilisi yempelaveki : Iziphumo zayo xa kunyangwa ukungasebenzi kakuhle kwe-erectile kunokuqhubeka ukuya kuthi ga kwiiyure ezingama-36.

Kwenzeka ntoni ukuba ndiphose idosi ye-tadalafil?

Idosi ephosiweyo inokuthathwa xa ikhunjulwa, kodwa ungathathi idosi enye ngosuku olunye. Abantu abane-pulmonary hypertension kuya kufuneka bathathe iipilisi ezingama-20 mg suku ngalunye. Musa ukwahlula ezi pilisi zimbini ngeedosi ezimbini ezahlukeneyo. Thatha ngexesha elinye. Ungaze uthathe iidosi ezongezelelweyo ze-tadalafil ukwenza idosi ephosiweyo.

Ndiyeka njani ukuthatha i-tadalafil?

I-Tadalafil ayenzi ukuxhomekeka emzimbeni, nangona amadoda asebenzisa i-tadalafil ngokugqithileyo ngaphandle kokuyalelwa anokuziva exhomekeke ngokwasemoyeni kunyango. I-Tadalafil inokuyekiswa ngaphandle kweempawu zokurhoxa okanye nasiphi na isidingo sedosi emiselweyo. Nangona kunjalo, abaguli abane-pulmonary hypertension kufuneka baqwalasele umboneleli wabo wezempilo ngaphambi kokumisa i-tadalafil.

Ezinye iimeko zinokufuna ukuba abantu bayeke kwangoko ukuthatha i-tadalafil, ngakumbi nayiphi na ilahleko ngequbuliso kumbono kwelinye okanye omabini amehlo okanye ukulahleka kwendlebe ngesiquphe, zombini eziya kufuna unyango olukhawulezileyo. Naluphi na ukungaphenduli kweziyobisi ezinje ngemingxuma, irhashalala, ukuphefumla nzima, okanye ukudumba ujikeleze ubuso okanye umqala ngumqondiso wokuba iyeza kufuneka limiswe de kube kugqitywe unobangela wokuphendula.

Leliphi elonaqondo liphezulu le-tadalafil?

Amadoda athatha i-tadalafil yokungasebenzi kakuhle kwe-erectile akufuneki athathe ngaphezulu kwe-20 mg ngosuku. Umthamo wemihla ngemihla ophakanyisiweyo wexinzelelo lwe-pulmonary hypertension ngu-40 mg ngosuku kwaye akufanele udlule. Amayeza agqithisileyo anyusa kakhulu umngcipheko woxinzelelo lwegazi oluyingozi, ukunyuka okude kunye nobuhlungu, utshintsho lweentliziyo, kunye nombono okanye ukulahleka kwendlebe.

Yintoni edibana netadalafil?

Ukutya akuchaphazeli ukubanakho komzimba ukufunxa i-tadalafil. Nangona kunjalo, thintela iidiliya okanye ijusi yeziqhamo. Isiqhamo samagilebhisi sinezinto eziphazamisa ukubanakho komzimba wokwephula i-tadalafil.

I-Tadalafil imetabolism yi-enzyme CYP3A4. Amanye amayeza amaninzi anokunyusa okanye anciphise umsebenzi wale enzyme, enokuthi ikhokelele ekuphakamiseni okanye ekunciphiseni umsebenzi we-tadalafil. Ngaba umboneleli wakho wokhathalelo lwempilo uphonononge uluhlu lwakho lwamayeza ukumisela ukuba ikhona na le mibambano inxulumene namayeza malunga nawe .. Amayeza athile oxinzelelo lwegazi, anje ngee-alpha blockers, kunye neziyobisi ze-erectile dysfunction ezifana ne-tadalafil njenge ildenafil , ziyafumaneka njenge Viagra okanye Uhlaziyo , kunye vardenafil , Kuthengiswe phantsi kwegama lophawu ILevitra , Kuya kufuneka kuthintelwe ngenxa yokuncitshiswa koxinzelelo lwegazi ukuba kuthathwe kunye ne-tadalafil. Nabani na othatha i-nitrate, esetyenziselwa iintlungu zesifuba, iimeko zentliziyo, kunye noxinzelelo oluphezulu, kufanelekile ukuthintela i-tadalafil. Thetha nomboneleli wakho wezempilo malunga nalo lonke unxibelelwano olunokwenzeka kwaye ukuba i-tadalafil ilungile kuwe.