I-Effexor vs Wellbutrin: Umahluko, ukufana, kwaye kukuphi okungcono kuwe
Iziyobisi Vs. UmhloboUkujonga ngokubanzi iziyobisi kunye nolwahluko ophambili | Imiqathango inyangwa | Ukusebenza | Ukuhlawulwa kwe-inshurensi kunye nokuthelekiswa kweendleko | Imiphumela | Ukusebenzisana kweziyobisi | Izilumkiso | FAQ
I-Effexor (venlafaxine) kunye ne-Wellbutrin (bupropion) ngamayeza amabini ahlukeneyo anokusetyenziswa ukunyanga uxinzelelo. Zombini i-Effexor kunye ne-Wellbutrin zisebenza ngokwandisa ii-neurotransmitters ezithile, ezinje nge-norepinephrine kunye ne-dopamine, kwingqondo. Ukulinganisa ezi neurotransmitters kunokunceda ukuphucula imood, ukukhuthaza ukulala okungcono, kunye nokunyusa umdla wakho wokutya kunye nokugxila. Amachiza oxinzelelo ayanceda ekunyangeni ezinye iingxaki zempilo yengqondo ukongeza kuxinzelelo olukhulu.
Ngaphandle kokufana, i-Effexor kunye ne-Wellbutrin zisebenza ngokwahlukileyo kwaye ziyavunywa i-FDA ukunyanga iimeko ezahlukeneyo.
Nguwuphi umahluko ophambili phakathi kwe-Effexor kunye ne-Wellbutrin?
I-Effexor ligama lophawu lwe-venlafaxine. Yimichiza efanayo nePristiq (desvenlafaxine) kwaye yeyeklasi yeziyobisi ebizwa ngokuba yi-serotonin-norepinephrine reuptake inhibitors (SNRIs). I-Effexor isebenza ngokuthintela ukubuyiselwa kwakhona kwe-serotonin, norepinephrine, kunye ne-dopamine kwingqondo. Ukuthintela ukubuyiselwa kwabo kwakhona, okanye ukuphinda bakuthathe, kuyonyusa ukubakho kwabo kunye neziphumo zizonke.
Igama leBrand-igama elithi Effexor kwiipilisi ezikhutshwa kwangoko luyekile. Endaweni yoko, makwenziwe ifom yokukhupha eyandisiweyo ebizwa ngokuba yi-Effexor XR. I-Effexor XR iza ngamandla e-37.5 mg, 75 mg, kunye ne-150 mg.
I-Wellbutrin ligama lophawu lwe-bupropion. Yinto eyodwa yokulwa uxinzelelo oluchazwe njenge-aminoketone. I-Wellbutrin kukholelwa ukuba iyasebenza ngokuthintela ukuphinda kuthathwe i-norepinephrine kunye ne-dopamine neurotransmitters yokunyusa iziphumo. Ngokungafaniyo ne-Effexor, iWellbutrin ayitshintshi amanqanaba e-serotonin kakhulu.
I-Wellbutrin iza neepilisi zomlomo ezikhutshwa kwangoko ngamandla e-75 mg okanye ye-100 mg. Nangona kunjalo, ihlala ichazwa njengethebhulethi ekhutshwa ngokuzinzileyo (Wellbutrin SR) okanye ithebhulethi yokukhupha eyandisiweyo (Wellbutrin XL). I-Wellbutrin SR kunye ne-Wellbutrin XL zikhutshwa ngokuthe ngcembe emzimbeni kwaye zinokuthathwa kube kanye ngosuku.
| Umahluko ophambili phakathi kwe-Effexor kunye ne-Wellbutrin | ||
|---|---|---|
| Umncedisi | Wellbutrin | |
| Iklasi yeziyobisi | I-Serotonin-norepinephrine reuptake inhibitors (SNRIs) | Aminoketone |
| Uhlobo lweBrith / generic | Ibhranti kunye nohlobo oluqhelekileyo olukhoyo | Ibhranti kunye nohlobo oluqhelekileyo olukhoyo |
| Ngubani igama eliqhelekileyo? | IVenlafaxine | IBupropion |
| Zeziphi iifom eza nalo iziyobisi? | Ithebhulethi yomlomo | Ithebhulethi yomlomo |
| Ithini idosi esemgangathweni? | Ekuqaleni, i-75 mg ngosuku. Idosi inokunyuswa nge-75 mg ngosuku yonke imihla ye-4. Idosi ayifanele ukudlula ubuninzi be-225 mg ngosuku ngeedosi ezahluliweyo. | Ekuqaleni, i-100 mg kabini yonke imihla. Emva kweentsuku ezi-3, idosi inokunyuswa iye kuma-100 mg amaxesha ama-3 yonke imihla. Idosi akufuneki idlule idosi enye ye-150 mg ngexesha. |
| Lude kangakanani unyango oluqhelekileyo? | Unyango lwexesha elide | Unyango lwexesha elide |
| Ngubani oqhelekileyo usebenzisa amayeza? | Abantu abadala abaneminyaka eli-18 nangaphezulu | Abantu abadala abaneminyaka eli-18 nangaphezulu |
Imiqathango ephathwe ngu-Effexor no-Wellbutrin
I-Effexor inelebheli yokunyanga uxinzelelo olukhulu okanye uxinzelelo olukhulu lokudakumba. Inokunyanga ukuphazamiseka koxinzelelo, phakathi kwezinye iimeko zempilo yengqondo. Ukukhupha i-venlafaxine kwangoko kunokunceda ekunyangeni uloyiko ngelixa ifom ekhutshiweyo eyamkelweyo inyangwa uxinzelelo ngokubanzi loxinzelelo . Ukusetyenziswa kwelebheli ye-Effexor kubandakanya unyango lokuphazamiseka okungafunekiyo (OCD) kunye ne-premenstrual dysphoric disorder (PMDD).
I-Wellbutrin i-FDA yamkelwe ukunyanga uxinzelelo olukhulu lokudakumba kunye nokuphazamiseka kwonyaka. Ngamanye amaxesha lisetyenziswa njengechiza elingekho kwilebula ukunyanga ukuphazamiseka kwengqondo, ukungahambi kakuhle kwengqondo (ADHD), kunye nokungasebenzi kakuhle ngokwesondo okubangelwa yi-SSRI anti-depressants.
| Imeko | Umncedisi | Wellbutrin |
| Uxinzelelo olukhulu lokudakumba | Ewe | Ewe |
| Ukuphazamiseka koxinzelelo ngokubanzi | Ewe | Hayi |
| Ukuphazamiseka kovalo | Ewe | Hayi |
| Ubume obungalunganga obuphambanisayo | Ngaphandle kwelebheli | Hayi |
| Ukuphazamiseka kwangaphambi kokuya exesheni | Ngaphandle kwelebheli | Hayi |
| Ukuxhuzula | Ngaphandle kwelebheli | Ngaphandle kwelebheli |
| Ukuqwalaselwa kwentsilelo yokuchaphazeleka kwengqondo (ADHD) | Ngaphandle kwelebheli | Ngaphandle kwelebheli |
| Ukuphazamiseka okwenzeka ngamaxesha athile onyaka | Ngaphandle kwelebheli | Ewe |
Ngaba i-Effexor okanye i-Wellbutrin isebenza ngakumbi?
I-Effexor kunye ne-Wellbutrin ngamayeza afanelekileyo okunyanga iimpawu zoxinzelelo. Nangona kunjalo, i-anti-depressant esebenzayo yeyona isebenza ngcono kuwe.
Ngokwe- Uhlalutyo lweemeta , I-Effexor kunye ne-Wellbutrin ziyasebenza ngokunyanga abantu abadala abanengxaki yokudakumba. Nangona bobabini besebenza ngokufanayo, iWellbutrin ibonakalisiwe ukuba ivelise ukungasebenzi kakuhle ngokwesondo njengempembelelo yecala. Ukungasebenzi gwenxa ngokwesondo sisiphumo secala esiqhelekileyo se-antidepressants, ngakumbi i-serotonin reuptake inhibitors (SSRIs) ekhethiweyo.
I-Wellbutrin kunye ne-Effexor ziye zafaniswa ne-SSRI anti-depressants efana ne-sertraline, i-escitalopram, i-fluoxetine, i-paroxetine kunye ne-duloxetine. Ulingo lwezonyango lubonakalisile i-Wellbutrin iyafana ngokusebenza kwii-SSRI. Ngokuchasene noko, i-Effexor ibikhona ifunyenwe isebenza ngakumbi Ngaphezulu kwee-SSRI, nangona abantu abaninzi banokuyeka ukuthatha i-Effexor ngenxa yeziphumo ebezingalindelekanga.
Qhagamshelana nomboneleli wakho wezempilo ukuze ufumane olona nyango lulungileyo. Emva kovavanyo olupheleleyo lweempawu zakho xa zizonke, ugqirha wakho uya kusebenza nawe ukufumana amayeza afanelekileyo.
Umyinge kunye nokuthelekiswa kweendleko ze-Effexor vs.Wellbutrin
I-Effexor XR ifuna ugqirha. Ihlala igutyungelwe luninzi lwezonyango kunye nezicwangciso zeinshurensi. Ukubonelelwa ngeentsuku ezingama-30 zeepilisi ezingama-75 mg, ixabiso eliqhelekileyo lokuthengisa lijikeleze i- $ 146. Sebenzisa ikhadi le-Effexor XR elilodwa lokugcina kunokuhlisa eli xabiso ukuya kuthi ga kwi-15 yeedola kuxhomekeke kwikhemesti oyisebenzisayo.
Ugqirha wakho uya kumisela i-Wellbutrin SR okanye i-Wellbutrin XL. Ezi nguqulelo ze-Wellbutrin zikhupha iyeza ngokuthe ngcembe emzimbeni. Uninzi lwezonyango kunye nezicwangciso zeinshurensi ziya kubandakanya i-Wellbutrin XL okanye i-Wellbutrin SR. Ukuba awunayo i-inshurensi, ixabiso lentengo eliphakathi kwe-Wellbutrin linokuba ngaphezulu kwe- $ 100. Nokuba unayo i-inshurensi, ungasebenzisa ikhadi le-Wellbutrin XL elilodwa okanye ikhadi le-Wellbutrin SR elilodwa lokugcina imali kwi-odolo yakho.
| Umncedisi | Wellbutrin | |
| Ngokuqhelekileyo ihlawulwa yi-inshurensi? | Ewe | Ewe |
| Ngokuqhelekileyo ihlanganiswe yiCandelo le-Medicare? | Ewe | Ewe |
| Umthamo osemgangathweni | I-Effexor XR: Iipilisi ezingama-75 mg kanye yonke imihla (ubungakanani be-30) | I-Wellbutrin SR / XL: 150 mg kanye yonke imihla (ubungakanani be-30) |
| I-Medicare copay eqhelekileyo | $ 0- $ 1 | $ 0- $ 22 |
| Ixabiso elilodwa | $ 15 + | $ 11 + |
Iziphumo eziqhelekileyo ezichaphazelekayo ze-Effexor vs.Wellbutrin
Iziphumo eziqhelekileyo ezichaphazelekayo ze-Effexor ukozela, ukulala, ukuxakeka, ukukhathazeka, isicupunu kunye nentloko. Ezinye iziphumo ebezingalindelekanga eziqhelekileyo zibandakanya umlomo owomileyo, ubuthathaka bemisipha, ukubila, kunye nokunyuka kwentliziyo (ukubetha kwentliziyo). Iziphumo zesondo , kubandakanya ukungasebenzi kakuhle ngokwesondo kunye nokudumba okungaqhelekanga, kuqhelekile ngelixa kusetyenziswa i-Effexor.
Iziphumo eziqhelekileyo ze-Wellbutrin ukulala, ukuxakeka, umlomo owomileyo, isicupunu, intloko kunye nokujuluka. I-Wellbutrin inokubangela uloyiko, ubuthathaka bemisipha, kunye nokubetha, phakathi kwezinye iziphumo ebezingalindelekanga.
I-Effexor kunye ne-Wellbutrin nayo inokubangela utshintsho kubunzima. Zombini ezi zidandateki zinokubangela ukutyeba okanye ukwehla kobunzima kuxhomekeke kwimpendulo yakho kwichiza.
Iziphumo ebezingalindelekanga ezimandundu ze-Effexor kunye ne-Wellbutrin zibandakanya iingxaki zempilo yengqondo entsha okanye ebuthathaka, iingcinga zokuzibulala, ukuphazamiseka kunye nobutshaba. Jonga naluphi na utshintsho kwiimvakalelo ngelixa uthatha la mayeza. Qhagamshelana nomboneleli wakho wezempilo ukuba ufumana nayiphi na imiphumo emibi.
| Umncedisi | Wellbutrin | |||
| Imiphumela | Iyasebenza? | Rhoqo | Iyasebenza? | Rhoqo |
| Ukozela | Ewe | 3% | Hayi | - |
| Ukuphuthelwa | Ewe | 3% | Ewe | 19% |
| Ukuba nesiyezi | Ewe | 3% | Ewe | 22% |
| Uvalo | Ewe | Mbini% | Ewe | 3.1% |
| Umlomo owomileyo | Ewe | Mbini% | Ewe | 28% |
| Isicaphucaphu | Ewe | 6% | Ewe | 2. 3% |
| Intloko ebuhlungu | Ewe | 3% | Ewe | 26% |
| Ubuthathaka bemisipha | Ewe | Mbini% | Ewe | * |
| Iipalpitations | Ewe | * | Ewe | 4% |
| Ukubila | Ewe | Mbini% | Ewe | 22% |
| Ukudumba okungaqhelekanga | Ewe | 3% | Hayi | - |
* akuxelwa
Ukuphindaphinda akusekelwanga kwidatha ukusuka kuvavanyo lwentloko ukuya entloko. Olu alunakuba luluhlu olupheleleyo lweziphumo ezibi ezinokwenzeka. Nceda ujonge ugqirha wakho okanye umboneleli wezempilo ukuze ufunde okungakumbi.
Umthombo: Ilebheli ye-FDA ( Umncedisi Ileta ye-FDA, Wellbutrin )
Ukusebenzisana kweziyobisi kwe-Effexor vs.Wellbutrin
I-Effexor kunye ne-Wellbutrin inokusebenzisana ne-monoamine oxidase inhibitors (MAOIs). Ukuthatha i-MAOI, njenge-isocarboxazid okanye i-phenelzine, kunye ne-Effexor okanye i-Wellbutrin kunokunyusa umngcipheko wesifo se-serotonin. I-Effexor kunye ne-Wellbutrin akufuneki zithathwe nge-MAOI okanye kwiintsuku ezili-14 zokumisa i-MAOI.
I-Effexor kunye ne-Wellbutrin inokusebenzisana neziyobisi ze-serotonergic. Umzekelo, ukuthatha ichiza le-serotonergic njenge-nortriptyline, i-tricyclic antidepressant, kunokunyusa umngcipheko we-serotonin syndrome xa idityaniswe nenye ye-anti-depressant. I-Effexor kunye ne-Wellbutrin kufuneka kwakhona ithintelwe nge-St. John's wort, ichiza elenza amakhambi elisetyenziswa rhoqo kwiziphumo zalo zokulwa noxinzelelo. Tshela ugqirha wakho ukuba uthatha ezinye izinto zokudakumba ngaphambi kokuqala i-Effexor okanye i-Wellbutrin.
I-Effexor kunye ne-Wellbutrin inokuchaphazela imisebenzi yeeplatelets kunye nokujiya kwegazi. Ukusetyenziswa kwe-Effexor okanye i-Wellbutrin kunokunciphisa ukusebenza kwe-warfarin okanye ezinye i-anticoagulants.
| Iziyobisi | Iklasi yeziyobisi | Umncedisi | Wellbutrin |
| Isocarboxazid IPhenelzine Selegiline | I-Monoamine oxidase inhibitors (i-MAOIs) | Ewe | Ewe |
| ILithium Umgca weNortriptyline Wort yaseSt | Iziyobisi zeSerotonergic | Ewe | Ewe |
| IWarfarin | Iintsholongwane | Ewe | Ewe |
Nxibelelana noochwephesha kwezolunye unxibelelwano olunokubakho ngeziyobisi.
Izilumkiso ze-Effexor kunye ne-Wellbutrin
Ukusetyenziswa kwe-Effexor okanye i-Wellbutrin kunokukhokelela kumngcipheko okhulayo wokucinga ngokuzibulala, ngakumbi kulutsha nakubantu abadala abancinci. Ukuziphatha kunye nokutshintsha kwemo kufuneka kubekwe esweni xa uqala amayeza afana ne-Effexor okanye i-Wellbutrin. Ukuba ufumana utshintsho olukhulu ekuziphatheni, i-antidepressants inokuyekiswa okanye ihlengahlengiswe ngumboneleli wakho wezempilo.
I-Effexor kunye ne-Wellbutrin inokunyusa uxinzelelo lwegazi. Ke ngoko, kubalulekile ukubeka esweni uxinzelelo lwegazi ngelixa usela la mayeza. Dibana nogqirha wakho ukuba unembali yoxinzelelo lwegazi oluphezulu ngaphambi kokuba uthathe la mayeza.
Ezinye i-anti-depressants ezifana nee-SSRI kunye nee-SNRI zinokunyusa umngcipheko wokopha. I-Effexor kufuneka ithintelwe nge-anticoagulants kunye nezinye iziyobisi ezichaphazela ukujiya kwegazi. I-Wellbutrin, engeyiyo i-SSRI okanye i-SNRI, yiyo mancinci amathuba okuba ichaphazele imisebenzi yeplatelet .
Xa isetyenziswa ngamachiza e-serotonergic, i-Effexor kunye ne-Wellbutrin inokunyusa umngcipheko wesifo se-serotonin. Iimpawu zeserotonin syndrome zibandakanya ukonyuka kwentliziyo, ukonyusa uxinzelelo lwegazi kunye nomkhuhlane. Dibana nogqirha wakho xa unazo naziphi na kwezi mpawu. Iserotonin syndrome inokufuna unyango olukhawulezileyo.
Imibuzo ebuzwa rhoqo malunga ne-Effexor vs Wellbutrin
Yintoni i-Effexor?
I-Effexor liyeza elinegama lebrendi elisetyenziselwa ukunyanga uxinzelelo olukhulu. Igama eliqhelekileyo le-Effexor yi-venlafaxine. I-Effexor XR yinguqulelo ekhutshiweyo ye-Effexor kwaye inokuthathwa kanye yonke imihla. I-Effexor inokunyanga uxinzelelo kunye nokuphazamiseka.
Yintoni iWellbutrin?
I-Wellbutrin yaziwa ngegama layo eliqhelekileyo elithi bupropion. Isetyenziselwa ukunyanga isifo esikhulu sokudakumba. I-Wellbutrin ihlala ichazwa njenge-Wellbutrin SR okanye i-Wellbutrin XL yokunyanga uxinzelelo kunye nezinye iimeko zempilo yengqondo. Ifom yokukhululwa kweWellbutrin inokuthathwa kanye yonke imihla.
Ngaba i-Effexor kunye ne-Wellbutrin efanayo?
Zombini i-Effexor kunye ne-Wellbutrin zinokunyanga iimpawu zoxinzelelo. Nangona kunjalo, i-Effexor yi-serotonin-norepinephrine reuptake inhibitor (SNRI) kunye ne-Wellbutrin yi-aminoketone. Ke ngoko, la machiza asebenza ngeendlela ezahlukeneyo. Banokusetyenziswa okuvunyiweyo okwahlukeneyo kwe-FDA.
Ngaba i-Effexor okanye i-Wellbutrin ibhetele?
I-Effexor kunye ne-Wellbutrin zombini iziyobisi ezisebenzayo ezonyanga uxinzelelo. I-Effexor ibhetele kune-Wellbutrin yokunyanga ukuphazamiseka koxinzelelo olunamava ecaleni koxinzelelo. Nangona kunjalo, xa kuthelekiswa ne-Wellbutrin, i-Effexor inokubangela ngaphezulu kweziphumo ebezesondo, ezinje nge-ejaculation engaqhelekanga kunye nokungabi namandla.
Ndingayisebenzisa i-Effexor okanye i-Wellbutrin ngelixa ndikhulelwe?
I-Effexor kunye ne-Wellbutrin bakudidi lokukhulelwa C kwaye banokunyusa umngcipheko weziphene zokuzalwa. Omabini la machiza afihlwa kubisi lwebele. Ukusetyenziswa kwe-Effexor kunye ne-Wellbutrin kufuneka kulunyukiswe okanye kuthintelwe ngexesha lokukhulelwa.
Ndingayisebenzisa iEffexor okanye iWellbutrin ngotywala?
Akukhuthazwa ukusela utywala ngelixa uthatha i-Effexor okanye i-Wellbutrin. Ukusetyenziswa kotywala nge-Effexor okanye i-Wellbutrin kunokukhokelela ekonyukeni ukozela, ukuba nesiyezi, kunye nezinye iziphumo ebezingalindelekanga. Ukusetyenziswa kotywala kunokwandisa umngcipheko wokubanjwa kwabantu abathatha i-Wellbutrin.
