INucynta vs. oxycodone: Umahluko, ukufana, kwaye kukuphi okungcono kuwe
Iziyobisi Vs. UmhloboUkujonga ngokubanzi iziyobisi kunye nolwahluko ophambili | Imiqathango iphathwe | Ukusebenza | Ukuhlawulwa kwe-inshurensi kunye nokuthelekiswa kweendleko | Imiphumela | Ukusebenzisana kweziyobisi | Izilumkiso | FAQ
I-Nucynta kunye ne-oxycodone zimbini-zamkelwe yi-FDA opioid amayeza amiselweyo aboniswe kunyango lweentlungu eziqatha. Ngokuqhelekileyo zisetyenziselwa iintlungu ezingenakukhululwa ngamayeza angenayo i-opioid, okanye xa isiguli singakwazi ukunyamezela ezinye iindlela. Omabini la mayeza eentlungu ahlelwa njengee-narcotic ( IShedyuli II ), Oko kuthetha ukuba banokubakho okuphezulu kokuxhatshazwa okanye ukuxhomekeka.
Indlela iNucynta esebenza ngayo ayiqondwa ngokupheleleyo. Olunye uphononongo lubonakalisile ukuba iNucynta yi-mu receptor (i-pain receptor) i-agonist kunye ne-norepinephrine reuptake inhibitor, ekhokelela ekuthomalaliseni iintlungu. I-Oxycodone isebenza ngokuzibophelela kwi-mu receptors kwingqondo, ethoba okanye ithintele imiqondiso yeentlungu, ekhokelela kwintlungu.
Ngenxa yokuba omabini la mayeza anamandla kakhulu, aqhelekileyo asetyenziswa kwiimeko zolawulo lwentlungu apho isiqabu seentlungu (ezingezizo ezokudambisa iintlungu) esinamandla sinokungasebenzi okanye singanyamezeleka. Nangona omabini la machiza esetyenziselwa iintlungu eziqatha, zinokwahluka okuninzi, esiza kuthi sichaze apha ngezantsi.
Nguwuphi umahluko ophambili phakathi kweNucynta kunye ne-oxycodone?
INucynta (tapentadol) yi-opioid, okanye i-narcotic, i-analgesic (painkiller). Iyafumaneka ngegama legama njengokubini ukukhutshwa kwangoko kunye nokukhutshwa kwethebhulethi. Ithebhulethi yokukhupha eyandisiweyo ibizwa ngokuba yiNucynta ER. Idosi yokuqala yi-50 mg ukuya kwi-100 mg rhoqo kwiiyure ezine ukuya kwezintandathu njengoko kufuneka kwiintlungu. Idosi inokuhlengahlengiswa ngugqirha wakho, kwaye eyona idosi iphezulu yi-600 mg ngosuku.
I-Oxycodone ikwayi-analgesic opioid generic (kunye ne-oxycodone IR, yokukhutshwa kwangoko) kwaye iyafumaneka kwifom yegama legama njenge-Oxycontin-ithebhulethi ekhululayo. Idosi iyahluka, kodwa idosi eqhelekileyo yokukhupha iipilisi ze-oxycodone yi-5 ukuya kwi-15 mg qho kwiiyure ezine ukuya kwezintandathu njengoko kufuneka kwiintlungu.
| Umahluko ophambili phakathi kweNucynta kunye ne-oxycodone | ||
|---|---|---|
| I-Nucynta | Oxycodone | |
| Iklasi yeziyobisi | I-opioid (narcotic) iintlungu | I-opioid (narcotic) iintlungu |
| Uhlobo lweBrith / generic | Igama lebrand | Brand kunye generic |
| Ngubani igama eliqhelekileyo / igama lophawu? | Isizukulwana: Tapentadol | Igama lebrand: I-OxyIR (ukukhutshwa kwangoko), i-Oxycontin (isebenza ixesha elide) |
| Zeziphi iifom eza nalo iziyobisi? | Ithebhulethi yokukhululwa kwangoko Ithebhulethi yokukhululwa | Ithebhulethi yokukhululwa kwangoko I-capsule yokukhululwa kwangoko Ithebhulethi yokukhululwa Isisombululo somlomo |
| Ithini idosi esemgangathweni? | Ekuqaleni: 50 mg ukuya kwi-100 mg zonke iiyure ezi-4 ukuya kwezi-6 njengoko kufuneka. Umthamo unokuhlengahlengiswa ngugqirha xa kufuneka njalo. Ubuninzi be-700 mg ngosuku ngosuku lokuqala lonyango, emva koko idosi ephezulu yi-600 mg ngosuku ngosuku lokuqala | Ithebhulethi yokukhululwa kwangoko: I-5 ukuya kwi-15 mg zonke iiyure ezi-4 ukuya kwezi-6 njengoko kufuneka Ithebhulethi yokukhululwa: 20 mg rhoqo kwiiyure ezili-12 |
| Lude kangakanani unyango oluqhelekileyo? | Ixesha elifutshane, linokusetyenziswa ixesha elide ngokusekwe kwimeko yokuphathwa (njengentlungu engapheliyo) kunye nempendulo | Ixesha elifutshane, linokusetyenziswa ixesha elide ngokusekwe kwimeko yokuphathwa (njengentlungu engapheliyo) kunye nempendulo |
| Ngubani oqhelekileyo usebenzisa amayeza? | Abantu abadala | Abantu abadala |
Ngaba ufuna elona xabiso lilungileyo kwiNucynta?
Bhalisela izilumkiso zamaxabiso eNucynta kwaye ufumane ukuba amaxabiso atshintsha nini!
Fumana izilumkiso zamaxabiso
Iimeko eziphathwe yi-Nucynta kunye ne-oxycodone
Zombini i-Nucynta kunye ne-oxycodone zinesalathiso esinye kunyango, esokulawula iintlungu ezibuhlungu kubantu abadala ezinzima ngokwaneleyo ukuba zifuna i-opioid analgesic, naxa olunye unyango lungonelanga okanye lunganyamezelwa.
| Imeko | I-Nucynta | Oxycodone |
| Ukulawulwa kwentlungu ebukhali kubantu abadala ebukhali ngokwaneleyo ukuba ifune i-opioid analgesic, kwaye xa ezinye iindlela zonyango zingonelanga | Ewe | Ewe |
Ngaba i-Nucynta okanye i-oxycodone isebenza ngakumbi?
Kwi ukufunda ngokuthelekisa ukukhutshwa kwangoko kwe-Nucynta kunye nokukhululwa kwangoko kwe-oxycodone kwizigulana ezinomndilili ukuya kwiintlungu ezibuhlungu zangasemva, omabini la machiza afunyanwa ekhuselekile ngokufanayo kwaye esebenza ngokunyanga iintlungu zangasemva, kunye nentlungu yomlenze ehambelana nayo. Izigulana zaseNucynta zazineziphumo ezibi ezimbalwa ezinxulumene nesisu.
Kwi ukufunda ngokuthelekisa amandla oxhatshazo lwezigulana ezithatha i-Nucynta okanye i-oxycodone, iNucynta yafunyanwa inamandla amancinci okuphathwa gadalala.
Olona nyango lusebenzayo kuwe kufuneka luchazwe kuphela ngugqirha wakho oza kujonga imeko (yezonyango) yakho, imbali kunye namanye amayeza owathathayo.
Umyinge kunye neendleko zokuthelekisa i-Nucynta vs. oxycodone
Ngenxa yemithetho yelizwe, ukuba ufumana i-opioid painkiller okokuqala, kunokwenzeka ukuba ufumane ubuncinci.
Ukugqunywa kweinshurensi kuyahluka ngeNucynta. Kuba ibiza kakhulu kwaye ifumaneka kuphela kwigama lophawu, ikopi yakho isenokuba phezulu, okanye ichiza linokufuna ugunyaziso lwangaphambili kwinkampani yakho yeinshurensi. I-Nucynta ngokubanzi ayigutyungelwanga yi-Medicare Part D. Amaxabiso aphuma epokothweni eNucynta 50 mg, amacwecwe angama-30 ahlala ejikeleze i-250 yeedola kodwa ungayifumana isezantsi njenge- $ 211 ngesaphulelo se-SingleCare.
I-Oxycodone ihlala igutyungelwe yi-inshurensi kunye necandelo le-Medicare Part D. Ixabiso elivela epokothweni elingama-30, 5 iipilisi ze-mg zinokubiza malunga ne-100 leedola kodwa ungasebenzisa isigqebhezana esinye kwiikhemesti ezithatha inxaxheba kwaye uziqale kwi- $ 36.
| I-Nucynta | Oxycodone | |
| Ngokuqhelekileyo i-inshurensi? | Iyahluka | Ewe |
| Ngokuqhelekileyo ihlanganiswe yiCandelo le-Medicare? | Hayi | Ewe |
| Umthamo osemgangathweni | 50 mg, # 30 iipilisi | 5 mg, # 30 iipilisi |
| Uhlobo oluqhelekileyo lweMedicare Part D | $ 95- $ 482 | $ 2- $ 56 |
| Ixabiso elilodwa | $ 211 + | $ 36- $ 62 |
Iziphumo eziqhelekileyo ezichaphazelekayo zeNucynta vs. oxycodone
Iziphumo ebezingalindelekanga ezixhaphakileyo zeNucynta sisicaphucaphu, ukugabha, ukozela, isiyezi, ukuqhina, umlomo owomileyo kunye nokurhawuzelela. Uxinzelelo olukhulu lokuphefumla (ukuphefumla okucothayo, ukungafumani oksijini yaneleyo), enokusongela ubomi okanye ibulale, inokwenzeka.
Nge-oxycodone, iipesenti ezichanekileyo azixelwanga, ngaphandle kokuba iziphumo ebezingalindelekanga zenzeke ngaphezulu kune-3% yezigulana. Iziphumo ebezingalindelekanga zixhaphakileyo sisicaphucaphu, ukuqhina, ukugabha, intloko ebuhlungu, pruritus (ukurhawuzelela), ukuqaqanjelwa sisisu, ukuba nesiyezi, ukuba buthathaka kunye nokozela. Iziphumo ezibi ezigwenxa zinokubandakanya uxinzelelo lokuphefumla, ukubanjwa kokuphefumla (ukuyeka ukuphefumla), ukubanjwa kwentliziyo (ukuphulukana nokusebenza kwentliziyo ngesiquphe, ukuphefumla kunye nokuqonda), uxinzelelo lwegazi oluphantsi, kunye / okanye ukothuka.
Ngenxa yomngcipheko omkhulu, kubalulekile ukuba xa uthatha iNucynta okanye i-oxycodone, uthathe eli chiza kanye njengoko umiselwe kwaye ungathathi idosi eyongezelelweyo. Kuya kufuneka ujongwe noxinzelelo lokuphefumla, ngakumbi xa uqala elinye lala machiza okanye ngexesha lotshintsho kwidosi.
Ezinye izehlo ezimbi zinokwenzeka. Qhagamshelana nomboneleli wakho wezempilo uluhlu olupheleleyo lweziphumo ebezingalindelekanga.
| I-Nucynta | Oxycodone | |||
| Imiphumela | Iyasebenza? | Rhoqo | Iyasebenza? | Rhoqo |
| Isicaphucaphu | Ewe | 30% | Ewe | ≥3% |
| Ukuhlanza | Ewe | 18% | Ewe | ≥3% |
| Ukuqunjelwa | Ewe | 8% | Ewe | ≥3% |
| Umlomo owomileyo | Ewe | 4% | Ewe | % ayixelwanga |
| Ukozela | Ewe | Shumi elinantlanu% | Ewe | ≥3% |
| Ukuba nesiyezi | Ewe | 24% | Ewe | ≥3% |
| Ukurhawuzelela | Ewe | 5% | Ewe | ≥3% |
Umthombo: DailyMed ( I-Nucynta ), Yonke imihla ( yioocodone )
Ukudibana kweziyobisi neNucynta vs. oxycodone
Sebenzisa i-benzodiazepines okanye ezinye izinto zokudakumba ze-CNS, kubandakanya ezinye amayeza opioid , ngokudityaniswa ne-Nucynta okanye i-oxycodone inokukhokelela kuxinzelelo lwegazi, uxinzelelo lokuphefumla, i-sedation enzulu, ikhoma kunye / okanye ukufa. Umdibaniso kufuneka uthintelwe. Nangona kunjalo, ukuba akukho enye indlela ekhoyo, eyona idosi iphantsi yeyeza ngalinye ngeli xesha lifutshane kufuneka isetyenziswe, kwaye isigulana kufuneka sibekwe esweni ngokusondeleyo, ngakumbi ekuqaleni konyango kwaye ngalo naluphi na utshintsho lwedosi.
Ukuthatha i-Nucynta okanye i-oxycodone ngamachiza anyusa i-serotonin nako kunokunyusa umngcipheko isifo se-serotonin , imeko ebeka ubomi esichengeni ngenxa yesakhi serotonin. La machiza abandakanya i-anti-depressants efana ne-serotonin reuptake inhibitors, izihlunu eziphumlayo, i-MAO inhibitors (i-MAO inhibitors akufuneki isetyenziswe kwiintsuku ezili-14 zeNucynta okanye i-oxycodone), kunye nee-triptans ze-migraine.
Ukuthatha i-oxycodone ngamayeza athile ahlengahlengiswa yi-enzyme ebizwa ngokuba yi-CYP3A4 okanye i-CYP2D6 kunokubangela ukuhlangana kweziyobisi. La machiza ayaziwa njenge-enzyme inhibitors kwaye aquka ii-macrolide antibiotics, ii-azole antifungals, kunye ne-protease inhibitors. Ukuzisebenzisa kunye ne-oxycodone kunokubangela amanqanaba aphezulu e-opioid, anokuba yingozi kakhulu. La machiza ayasebenzisana ne-oxycodone, kodwa hayi iNucynta.
Amanye amachiza, abizwa ngokuba yi-enzyme inducers, aneziphumo ezichaseneyo njenge-inhibitors, ehlisa inqanaba le-opioid ukuze ingasebenzi okanye inokubangela neempawu zokurhoxa. I-inducers inokuchaphazela iNucynta okanye i-oxycodone.
Nxibelelana nomboneleli wakho wezempilo uluhlu olupheleleyo lokudibana kwamachiza.
| Iziyobisi | Iklasi yeziyobisi | I-Nucynta | Oxycodone |
| IAlprazolam IClonazepam Diazepam ILorazepam | IiBenzodiazepines | Ewe | Ewe |
| Utywala | Utywala | Ewe | Ewe |
| Ikhowudi Fentanyl IHydrocodone IHydromorphone Imethadone Imofini I-Tramadol | Iipioids | Ewe | Ewe |
| Baclofen ICarisoprodol ICyclobenzaprine Imetaxalone Tizanidine | Ukuphumla kwezihlunu | Ewe | Ewe |
| Amitriptyline Citalopram Desipramine I-Desvenlafaxine Duloxetine I-Escitalopram IFluoxetine | Ukudakumba | Ewe | Ewe |
| IPhenelzine I-Rasagiline Selegiline I-Tranylcypromine | I-MAO inhibitors | Ewe | Ewe |
| Furosemide IHydrochlorothiazide | Womchamo | Ewe | Ewe |
| I-Benztropine Idiphenhydramine Oxybutynin Itolterodine | Iziyobisi zeAnticholinergic | Ewe | Ewe |
| IAlmotriptan Eletriptan Rizatriptan ISumatriptan Zolmitriptan | I-Triptans yemigraine | Ewe | Ewe |
| Clarithromycin Erythromycin IFluconazole Ketoconazole Ritonavir | CYP3A4 okanye CYP2D6 inhibitors | Hayi | Ewe |
| ICarbamazepine IPhenytoin | I-CYP3A4 inducers | Ewe | Ewe |
Izilumkiso zeNucynta kunye ne-oxycodone
Kukho isilumkiso sebhokisi kwiNucynta kunye ne-oxycodone, esisilumkiso esomeleleyo esifunwa yi-FDA (e-United States yokutya kunye noLawulo lweeDrug).
- Iziyobisi ze-Opioid zinomngcipheko wokuba likhoboka, ukuxhatshazwa, kunye nokusetyenziswa gwenxa. Oku kunokukhokelela kukugqithisa kunye nokufa. Izigulana kufuneka zivavanywe umngcipheko ngaphambi kokuthatha i-opioid kwaye kufuneka zijongwe ngononophelo.
- I-Opioids inokubangela ukusongela okukhulu, ukusongela ubomi, okanye ukudakumba okubulalayo. Izigulana kufuneka zijongwe ngononophelo, ngakumbi xa unyango luqala, nasemva kokutshintsha kwethamo.
- Ukungena ngengozi, ngakumbi ngabantwana, kunokubangela ukubola okungaphezulu. Izigulana kufuneka zikhusele i-opioids kwindawo engenakufikelelwa ngabantwana, kwaye phantsi kwesitshixo kunye nesitshixo ukuba kunokwenzeka.
- Ukusetyenziswa kwexesha elide kwe-opioid ngexesha lokukhulelwa kunokubangela isifo sokurhoxa se-neonatal opioid syndrome, esinokuba semngciphekweni wobomi xa singaziwa kwaye sinyangwa.
- Sebenzisa ii-benzodiazepines ezinje ngeXanax, okanye ezinye izinto zokudakumba ze-CNS, ezinjengezinye i-opioids (okanye utywala), kunokubangela ukudakumba okunzulu, uxinzelelo lokuphefumla, ikhoma kunye nokufa. Ukudityaniswa kweeopioids kunye ne-benzodiazepines kufuneka kuthintelwe ukuba kunokwenzeka. Izigulana ekufuneka zithathe olu dibaniso ngenxa yezinye iindlela ezingasebenziyo kufuneka zinikwe eyona idosi isebenzayo kwelona xesha lifutshane kwaye kufuneka zibekwe esweni ngocoselelo.
Ezinye izilumkiso:
- Izigulana ezinesifo sokuphefumla, i-asthma ebukhali / ebukhali kwisimo esingabekwanga esweni, isithintelo samathumbu, okanye uvakalelo olukhulu nakweyiphi na into yezithako akufuneki isebenzise iNucynta okanye i-oxycodone.
- I-Nucynta okanye i-oxycodone akufuneki isetyenziswe kwizigulana ezinesifo esinganyangekiyo semiphunga okanye abagulayo okanye abagulayo.
- Iserotonin syndrome inokwenzeka, ngakumbi ngokusetyenziswa kweziyobisi ezonyusa amanqanaba e-serotonin, anje ngee-anti-depressants. Izigulana kufuneka zijongwe kutshintsho lobume bengqondo (ukuphazamiseka, ukubona izinto ezingekhoyo), utshintsho kuxinzelelo lwegazi, ukungahambelani, kunye / okanye iimpawu zesisu ezifana nesicanucanu, ukugabha, okanye urhudo. Isigulana kufuneka sifune unyango kwangoko ukuba kukho naziphi na kwezi mpawu zenzekayo kuba i-serotonin syndrome iyingozi kakhulu kwaye inokubulala.
- Ukungoneli kwe-adrenal kunokwenzeka, ngesiqhelo emva kwenyanga enye. Izigulana kufuneka zifune unyango ukuba zifumana isicaphucaphu, ukugabha, ukuphelelwa ngumdla, ukudinwa, ukuba buthathaka, isiyezi, kunye / okanye uxinzelelo lwegazi oluphantsi.
- I-Nucynta okanye i-oxycodone inokubangela uxinzelelo lwegazi olusezantsi.
- I-Nucynta okanye i-oxycodone akufuneki isetyenziswe kwizigulana ezinengxaki yokuziva kakuhle okanye kwi-coma.
- I-Nucynta okanye i-oxycodone inokunyusa umngcipheko wokubanjwa kwizigulana ezinengxaki yokuthimba.
- I-Nucynta okanye i-oxycodone akufuneki irhoxiswe ngesiquphe, kodwa endaweni yoko kufuneka icofwe kancinci.
- I-Nucynta akufuneki isetyenziswe kwizigulana ezinengxaki yesibindi okanye yezintso.
- Musa ukuqhuba okanye ukusebenzisa oomatshini de ube uyazi indlela elikuchaphazela ngayo iyeza.
- Iiopioid ezingakhuselekanga zinokuba yingozi komnye umntu ekhaya, kubandakanya neendwendwe. Gcina ngokukhuselekileyo, ngaphandle kwembonakalo kunye nokufikelela kwabantwana, nakwindawo engafikelelekiyo kwabanye. Buza kwingcali yakho ukuba ungazilahla njani ii-opioid ezingasetyenziswanga kwindawo yakho.
- Xa uthatha nayiphi na i-opioid, thetha nogqirha wakho malunga nonyango lwe-naloxone, iyeza elinokunyanga i-opioid overdose kwimeko engxamisekileyo.
Ngenxa yokuba kungekho zifundo zilawulwa kakuhle kwabasetyhini, iNucynta okanye i-oxycodone akufuneki isetyenziswe xa ukhulelwe. Sebenzisa i-opioids ngexesha lokukhulelwa, nokuba kusetyenziselwa unyango okanye kungasetyenziswa kunyango, kunokubangela ukuxhomekeka emzimbeni wosana, kwaye kunokukhokelela kwisifo sokurhoxa kwe-opioid ye-neonatal kungekudala emva kokuzalwa.
Imibuzo ebuzwa rhoqo malunga neNucynta vs. oxycodone
Yintoni iNucynta?
INucynta sisiyobisi, okanye i-opioid, ipilisi yeentlungu ebisetyenziselwa ukunyanga iintlungu. Iyafumaneka kwigama lophawu njengopapasho olukhawulezileyo (iNucynta) okanye ithebhulethi yokukhupha eyandisiweyo (iNucynta ER).
Yintoni ioxycodone?
I-Oxycodone yi-painkiller ye-narcotic esetyenziselwa ukunyanga iintlungu. Itholakala kwi-generic njengethebhulethi yokukhululwa ngokukhawuleza okanye i-capsule kunye negama legama njenge-Oxycontin ende.
Ngaba i-Nucynta kunye ne-oxycodone ziyafana?
Hayi, kodwa ziyafana. INucynta iqulethe i-tapentadol. I-Oxycodone kunye ne-tapentadol zombini zii-opioid analgesics (iipilisi zentlungu) kodwa zinomahluko, njengedosi, ixabiso, kunye neziphumo ebezingalindelekanga, ezichazwe apha ngasentla.
Ngaba i-Nucynta okanye i-oxycodone ingcono?
Kwi isifundo ngokuthelekisa amachiza amabini , I-Nucynta kunye ne-oxycodone zikhuselekile ngokufanayo kwaye ziyasebenza ekunyangeni iintlungu ezisezantsi. INucynta inokuba nayo amandla okuphatha gadalala . Thetha nogqirha wakho ukuba i-Nucynta okanye i-oxycodone ikulungele, ukuba ezinye izinto zokuthomalalisa iintlungu khange zikuncede okanye ukuba awukwazi ukuzinyamezela.
Ndingayisebenzisa iNucynta okanye i-oxycodone ngelixa ndikhulelwe?
Hayi. INucynta okanye ioxycodone (okanye nayiphi na i-opioid, enjengePercocet) inokubangela isifo sokurhoxa kwi-neonatal , ezinokuba yingozi okanye zisongele ubomi bosana.
Ndingayisebenzisa iNucynta okanye i-oxycodone ngotywala?
Hayi. Ukuthatha iNucynta okanye ioxycodone nge utywala ungawunyusa umngcipheko weziphumo ebezingalindelekanga ezimandundu ezinje ngokudakumba ngokuphefumla (ukungafumani oksijini yaneleyo, kunye nokuphefumla kwakho kuyehla) kwaye kungakhokelela ekubeni isiqaqa okanye ukufa.
Yintoni eyomeleleyo kuneNucynta?
Iidosi eziphezulu ze-opioids zinxulunyaniswa nomngcipheko ophezulu wokudlula kunye nokufa, ngokwe i-CDC . Kubalulekile ukujonga idosi yemihla ngemihla ye-opioids kwaye uguqulele kwi-MME (morphine milligram equivalents) ukubala umngcipheko wokudlula kunye nemfuno yokujonga ngokusondeleyo. Ukuba idosi yakho yeNucynta ayisebenzi kuwe, thetha nogqirha wakho malunga nokutshintsha idosi okanye ukutshintsha amayeza. Musa ukunyusa umthamo ngokwakho, ngaphandle kokuthetha nogqirha wakho. Ungaze uthathe i-opioid ye Sebenzisa enye ngaphandle kwalapho ibimiselwe .
Ngaba iNucynta iyafana ne-tramadol?
INucynta yomelele kwaye inamandla okulutha ngakumbi kune-tramadol-iNucynta sisiyobisi seShedyuli II, ngelixa i-tramadol sisiyobisi seShedyuli IV. INucynta ikwabiza kakhulu kune-tramadol, efumaneka kuzo zombini ii-generic kunye ne-brand (Ultram). Izigulana ezininzi zifumanisa ukuba i-tramadol yanele ukulawula iintlungu.
Ngaba iNucynta ibangela ukwehla kobunzima?
Ngaphantsi kwe-1% yezigulana kwiNucynta ER Phase 2 kunye no-3 kuvavanyo lweklinikhi babenayo ukuthoba ubunzima kodwa inani lokuphulukana nobunzima alichazwanga.
