I-Pantoprazole vs omeprazole: Umahluko, ukufana, kwaye kukuphi okungcono kuwe

Iziyobisi Vs. Umhlobo

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I-Pantoprazole kunye ne-omeprazole zimbini iiproton pump inhibitors (PPIs) ezisetyenziselwa ukunyanga iimeko zokwetyisa. Omabini la machiza anokusetyenziselwa isifo se-reflux se-gastroesophageal (GERD), uhlobo olunganyangekiyo lwentliziyo, kunye ne-esophagitis erosive. Basebenza ngokunciphisa i-acid secretion esiswini. Ngelixa i-pantoprazole kunye ne-omeprazole ngamayeza afanayo, nawo anomahluko.

Nguwuphi umahluko ophambili phakathi kwe-pantoprazole kunye ne-omeprazole?

I-Pantoprazole (i-Pantoprazole coupons) ligama elenziwe lafana ne-generic ye-Protonix kwaye ngoku ithengwa ngomyalelo kuphela. Kuvunyelwe i-FDA ukunyanga i-GERD kubantu abadala kunye nabantwana abaneminyaka emi-5 nangaphezulu ixesha eliqhelekileyo ukuya kuthi ga kwiiveki ezisibhozo. I-Pantoprazole (iinkcukacha ezingaphezulu ze-Pantoprazole) zinikezelwa njengethebhulethi yokukhupha ukulibaziseka okanye ukumiswa kolwelo. Inokuqhutywa kwakhona ngenaliti efakwa ngaphakathi (IV) esibhedlele okanye eklinikhi.

I-Omeprazole (i-Omeprazole coupons) ikwabizwa ngegama layo, iPrilosec, kwaye ingathengwa ngugqirha okanye ngaphezulu kwe-counter. Isebenza ngokufana ne-pantoprazole njenge-PPI. Nangona kunjalo, ikwayi-FDA-evunyiweyo ukunyanga izilonda zesisu, i-helicobacter pylori (H. pylori) usulelo, kunye nezilonda zesisu ukongeza kwi-GERD kunye ne-esophagitis erosive. I-Omeprazole (iinkcukacha ezithe kratya nge-Omeprazole) inokunyanga i-GERD kubantu abadala nakubantwana unyaka omnye nangaphezulu. Kuza njengokukhutshwa kokukhutshelwa kokulibaziseka, ithebhulethi, kunye nokumiswa kolwelo.

Umahluko ophambili phakathi kwe-pantoprazole kunye ne-omeprazole
	IPantoprazole	Omeprazole
Iklasi yeziyobisi	Iproton pump inhibitor (PPI)	Iproton pump inhibitor (PPI)
Uhlobo lweBrith / generic	Inguqulelo yesiqhelo iyafumaneka	Inguqulelo yesiqhelo iyafumaneka
Ngubani igama eliqhelekileyo? Ngubani igama lophawu?	IPantoprazole IProtonix	Omeprazole Iprilosec
Zeziphi iifom eza nalo iziyobisi?	Ithebhulethi yomlomo, ukukhutshwa kokulibaziseka Ukurhoxiswa ngomlomo Inaliti ye-IV / ukumiliselwa	Ithebhulethi yomlomo, ukukhutshwa kokulibaziseka Iphilisi yomlomo, ukukhutshwa kokulibaziseka Ukurhoxiswa ngomlomo Inaliti ye-IV / ukumiliselwa
Ithini idosi esemgangathweni?	40 mg kanye yonke imihla	20 mg kanye yonke imihla
Lude kangakanani unyango oluqhelekileyo?	Ukuya kuthi ga kwiiveki ezisibhozo	Iiveki ezi-4 ukuya kwezi-8
Ngubani oqhelekileyo usebenzisa amayeza?	Abantu abadala nabantwana abaneminyaka emi-5 nangaphezulu	Abantu abadala nabantwana unyaka omnye nangaphezulu

Iimeko zonyango lwe-pantoprazole kunye ne-omeprazole

I-Pantoprazole kunye ne-omeprazole bobabini bavunyelwe yi-FDA ukunyanga iimpawu zokubetha kwentliziyo ezivela kwi-GERD kunye ne-esophagitis erosive. Ii-PPI ezinjenge-pantoprazole kunye ne-omeprazole zinamandla ngakumbi kunee-antacids eziqhelekileyo, ezinjenge-histamine (H2) blocker. Zihlala zimiselwe unyango lwexesha elifutshane ayihlali ngaphezulu kweeveki ezisi-8 ubude.

I-Pantoprazole kunye ne-omeprazole inokunyanga iimeko ze-hypersecretory ezibangela ukuba isisu sivelise i-acid esiswini kakhulu. Isifo i-Zollinger-Ellison syndrome yimeko enokubangela i-acid hypersecretion kwaye ibandakanye amathumba kwi-pancreas okanye i-duodenum (icandelo lokuqala lamathumbu amancinci).

I-Pantoprazole kunye ne-omeprazole zinokunceda ekunyangeni ezinye iimeko ezinje ngezilonda zesisu, izilonda zesisu okanye isisu, kunye nezilonda. Ezi zilonda zihlala zibangelwa lusulelo olusuka kwintsholongwane ebizwa ngokuba nguH. Pylori. Ngelixa i-omeprazole ivunyiwe ukuba inyange iH. Pylori ngokudibeneyo namanye amachiza, i-pantoprazole isetyenziswa ngaphandle kwelebheli kwesi sifo.

Okunye ukusetyenziswa kwelebheli kuzo zombini iziyobisi kubandakanya isisu sikaBarrett kunye nezilonda ezibangelwa kukusetyenziswa kwamachiza angasebenziyo (i-NSAIDs).

Imeko	IPantoprazole	Omeprazole
Isifo se-Reflux seGastroesophageal (GERD)	Ewe	Ewe
Ukuqhuma kwesisu	Ewe	Ewe
Isifo seZollinger-Ellison	Ewe	Ewe
Iimeko Hypersecretory	Ewe	Ewe
Izilonda zesisu	Ngaphandle kwelebheli	Ewe
Izilonda esiswini	Ngaphandle kwelebheli	Ewe
H. Pylori usulelo	Ngaphandle kwelebheli	Ewe
Umqala kaBarrett	Ngaphandle kwelebheli	Ngaphandle kwelebheli
Ukutya	Ngaphandle kwelebheli	Ngaphandle kwelebheli
Izilonda ze-NSAID	Ngaphandle kwelebheli	Ngaphandle kwelebheli
Izilonda Peptic	Ngaphandle kwelebheli	Ngaphandle kwelebheli

Ngaba ufuna elona xabiso lilungileyo kwi-Omeprazole?

Bhalisela izilumkiso zamaxabiso e-Omeprazole kwaye ufumane ukuba amaxabiso atshintsha nini!

Fumana izilumkiso zamaxabiso

Ngaba i-pantoprazole okanye i-omeprazole isebenza ngakumbi?

I-Pantoprazole kunye ne-omeprazole zibonisiwe ukuba ziyasebenza ekunyangeni i-GERD. Kwi Uhlalutyo lweemeta abadibanise izifundo ezingaphezu kwe-40 ezahlukeneyo, iziphumo azifumananga mahluko ubonakalayo ekusebenzeni phakathi kwe-PPIs. I-Pantoprazole yafunyaniswa ukuba iyasebenza ngokulinganayo ne-omeprazole. Olunye uvavanyo lwezonyango olungaboniyo lukwabandakanya ezinye ii-PPI ezinje I-Nexium (esomeprazole) , i-lansoprazole (Prevacid), kunye ne-rabeprazole (Aciphex).

Nye ukufunda Kubandakanywa uhlalutyo lweemeta olufumanise ukuba i-pantoprazole yayisebenza ngakumbi kune-omeprazole kunyango lwezilonda esiswini. Iziphumo zidityanisiwe kwizifundo ze-5 ekusebenzeni okusekwe kuphononongo kwiqondo lokuphilisa. Ngelixa i-pantoprazole ifunyenwe isebenza ngakumbi, kunokuba nokubakho kweziphene zokulinganisa okungalinganiyo.

I-Pantoprazole kunye ne-omeprazole zombini iziyobisi ezinokuthelekiswa nokusebenza. Enye inokukhethwa kunenye ngokuxhomekeke kwimeko yokunyangwa kunye neendleko zonyango. Dibana nogqirha ukuze ubone ukuba yeyiphi I-PPI inokuba ngcono yeyakho.

Ukufunyanwa kunye nokuthelekiswa kweendleko ze-pantoprazole vs omeprazole

I-Pantoprazole liyeza eliqhelekileyo elihlala ligutyungelwe yiMedicare kunye nezicwangciso ezininzi zeinshurensi. Ixabiso eliphakathi lokuthengisa i-pantoprazole lijikeleze i- $ 522. Unokwazi ukugcina ngaphezulu nge-singleCare coupon enokuzisa iindleko ukuya kuthi ga kwi-28.

Fumana ikhadi lesaphulelo somntu ongatshatanga

I-Omeprazole liyeza elenziwe lafana nalawo aqhelekileyo ahlala egutyungelwe yiMedicare kunye nezicwangciso ezininzi zeinshurensi Ixabiso eliphakathi lokuthengisa kwi-omeprazole lijikeleze i- $ 67.99. Ngekhuphoni le-SingleCare unokulindela ukuhlawula nge- $ 9-20 yeedola ezingama-30, ezingama-20mg njengezingxobo.

	IPantoprazole	Omeprazole
Ngokuqhelekileyo ihlawulwa yi-inshurensi?	Ewe	Ewe
Ngokuqhelekileyo igutyungelwe yiMedicare?	Ewe	Ewe
Umthamo osemgangathweni	40 mg (ubungakanani be-30)	20 mg (ubungakanani be-30)
I-Medicare copay eqhelekileyo	Kuxhomekeke kwisicwangciso sakho seinshurensi	Kuxhomekeke kwisicwangciso sakho seinshurensi
Ixabiso elilodwa	$ 28	$ 9-20

Iziphumo eziqhelekileyo ezichaphazelekayo zepantoprazole kunye ne-omeprazole

I-Pantoprazole kunye ne-omeprazole zinokubangela iziphumo ebezingalindelekanga ezinje ngeentloko, isiyezi, isicaphucaphu kunye nokugabha. Kananjalo kunokubangela ezinye iziphumo ebezingalindelekanga zesisu ezinjengorhudo, ukuqhina, isisu okanye iintlungu zesisu, kunye nokuqunjelwa okanye igesi. Ezinye iziphumo ebezingalindelekanga ekwabelwana ngazo zinokubandakanya iintlungu ezidibeneyo, usulelo oluphezulu lokuphefumla, kunye ne-asthenia okanye ukunqongophala kwamandla.

I-Omeprazole inokubangela iziphumo ebezingalindelekanga ezinje nge-acid ukuphinda ubuye, iintlungu zomqolo kunye nokukhohlela. I-Pantoprazole khange ifundwe ukubonisa ezi ziphumo bezingalindelekanga rhoqo.

	IPantoprazole	Omeprazole
Imiphumela	Iyasebenza?	Rhoqo	Iyasebenza?	Rhoqo
Intloko ebuhlungu	Ewe	12.2%	Ewe	7%
Isicaphucaphu	Ewe	7%	Ewe	4%
Urhudo	Ewe	8.8%	Ewe	4%
Ukuqunjelwa	Ewe	<2%	Ewe	Mbini%
Intlungu zesisu	Ewe	6.2%	Ewe	5%
Ukuhlanza	Ewe	4.3%	Ewe	3%
Ukuqunjelwa sisisu	Ewe	3.9%	Ewe	3%
Ukuba nesiyezi	Ewe	3%	Ewe	Mbini%
Intlungu edibeneyo	Ewe	2.8%	Ewe	N / A
Irhashalala	Ewe	<2%	Ewe	Mbini%
Ukubuyiselwa kwe-Acid	Hayi	-	Ewe	Mbini%
Usulelo oluphezulu lokuphefumula	Ewe	N / A	Ewe	Mbini%
Ubuthathaka / ukunqongophala kwamandla	Ewe	N / A	Ewe	1%
Umqolo obuhlungu	Hayi	-	Ewe	1%
Khohlela	Hayi	-	Ewe	1%

Dibana nogqirha okanye usokhemisti ngazo zonke iziphumo ebezingalindelekanga ezinokubakho.
Umthombo: Mihla le (pantoprazole) , Yonke imihla (omeprazole)

Ukudibana kwesiyobisi kwi-pantoprazole vs omeprazole

Zombini iipantoprazole kunye ne-omeprazole zinokunxibelelana neziyobisi ezifanayo. Zombini zinokunxibelelana namayeza e-antiretroviral afana ne-rilpivirine, atazanavir, kunye ne-saquinavir. Ukuthatha la mayeza kunye kunokutshintsha ukusebenza kweziyobisi ze-antiretroviral kunye nokunyusa ityhefu. Ukuthatha i-pantoprazole okanye i-omeprazole nge-warfarin kunokunyusa umngcipheko wokopha. Ke ngoko, akufuneki zithathwe kunye. Ngelixa i-clopidogrel inokungachaphazeleka yi-pantoprazole, kufuneka ithintelwe nge-omeprazole.

I-Pantoprazole kunye ne-omeprazole zinxibelelana ne-methotrexate, iyeza le-antimetabolite, kwaye kunokubangela umngcipheko okhulayo wetyhefu kunye neziphumo ebezingalindelekanga.

I-Pantoprazole kunye ne-omeprazole akufuneki zithathwe ngaxeshanye neetyiwa zentsimbi kunye nezinye iziyobisi ezixhomekeke kwisisu esiswini sokufunxa. Olunye unyango oluxhomekeke kwisisu se-asidi sokufunxa lubandakanya iziyobisi ze-chemotherapy ezinje nge-erlotinib kunye ne-dasatinib kunye ne-antifungals ezifana ne-ketoconazole kunye ne-itraconazole.

Ngenxa yokuba zombini ii-PPIs zidibene esibindini, zinokunxibelelana nezinye iziyobisi ezenziwa zii-enzymes ezifanayo, kubandakanya i-CYP2C19 enzyme. Nangona kunjalo, ngokuka Ileta ye-FDA , amanye ala machiza, kubandakanya i-phenytoin, i-citalopram, kunye ne-diazepam, aziboniswanga zinonxibelelwano olubalulekileyo kunye ne-pantoprazole. Okwangoku, kubalulekile ukuba uxoxe nangawo nawaphi na amayeza owathathayo nogqirha ngaphambi kokuba uthathe iPPI.

Ii-PPI zinokuchaphazela iziphumo zovavanyo oluthile lweelebhu. Ii-PPI ziyaziwa ukuba zibangela iziphumo ezingalunganga zovavanyo lomchamo we-THC.

Iziyobisi	Iklasi yeziyobisi	IPantoprazole	Omeprazole
Rilpivirine UNelfinavir Atazanavir Saquinavir Ritonavir	IiNtsholongwane	Ewe	Ewe
IWarfarin	I-Anticoagulant	Ewe	Ewe
Clopidogrel	Antiplatelet	Hayi	Ewe
Imethotrexate	Antimetabolite	Ewe	Ewe
IMycophenolate mofetil ITacrolimus	Uxinzelelo	Ewe	Ewe
Ketoconazole Itraconazole Voriconazole	Ukubola	Ewe	Ewe
Erlotinib Dasatinib Nilotinib	Unyango ngamayeza	Ewe	Ewe
Yentsimbi fumarate Yentsimbi gluconate Isanti sulphate Isinyithi sifinya	Iityiwa zentsimbi	Ewe	Ewe
Diazepam IMidazolam	Benzodiazepine	Hayi	Ewe
IPhenytoin	Isifo sephepha	Hayi	Ewe
Clarithromycin Rifampin	Zintsholongwane	Ewe	Ewe
Citalopram	Ukukhetha i-serotonin reuptake inhibitor (SSRI) yoxinzelelo	Hayi	Ewe
Wort eSt	Amakhambi	Ewe	Ewe

* Olu alunakuba luluhlu olupheleleyo lwazo zonke izinto ezinokubakho xa kusenziwa iziyobisi. Dibana nogqirha nawo onke amayeza onokuthi uwathathe.

Izilumkiso ze-pantoprazole kunye ne-omeprazole

I-Pantoprazole kunye ne-omeprazole azikhuthazwa ukuba zisetyenziswe ixesha elide. Ukusetyenziswa kwexesha elide kudibene ne- ukwanda kwengozi yokuqhekeka kwamathambo . Ukuba une-osteoporosis, unokufuna ukubeka esweni nakuphi na ukusetyenziswa kwee-PPIs.

Olunye ulwazi lucebisile ukuba iziyobisi ze-PPI zinokunyusa umngcipheko weziganeko zentliziyo ezinje ngokuhlaselwa kwentliziyo kunye nokubetha. Nangona kunjalo, i-FDA kunye nezinye iingxelo Ukuqinisa izibonelelo ze-PPIs kungaphezulu komngcipheko.

Ngenxa yokuba i-pantoprazole kunye ne-omeprazole ziqhubekeka esibindini, zinokuhlengahlengiswa okanye zithintelwe kwezo zinokukhubazeka kwesibindi.

I-Pantoprazole kunye ne-omeprazole zinokuba mandundu okanye zonyuse umngcipheko we-systemic lupus erythematosus, isifo esingaqhelekanga somzimba.

Unyango nge-PPIs lunokunyusa umngcipheko wohudo olusuka kwizifo zeClostridium difficile. Lo mngcipheko unokuphakama kwabo balaliswe esibhedlele ixesha elide.

Zombini i-pantoprazole kunye ne-omeprazole zikuluDidi C lokukhulelwa kwaye zinokubangela ingozi kusana olungekazalwa. Qhagamshelana nogqirha okanye umboneleli wezempilo ukuba ukhulelwe okanye uncelisa.

Imibuzo ebuzwa rhoqo malunga nepantoprazole vs. Omeprazole

Yintoni i-pantoprazole?

I-Pantoprazole (Protonix) lunyango lwe-proton pump inhibitor (PPI) emiselweyo ukunyanga i-GERD kunye ne-esophagitis erosive. Ihlala ithathwa njengepilisi ye-40 mg yokulibaziseka-yokukhululwa ukuya kuthi ga kwiiveki ezisibhozo. Ingathathwa kubantu abadala kunye nabantwana kwiminyaka emi-5 nangaphezulu.

Yintoni i-omeprazole?

I-Omeprazole (Prilosec) lunyango lwe-PPI olumiselweyo ukunyanga i-GERD kunye ne-esophagitis erosive. Kukwayinto evunyiweyo ye-FDA yokusulelwa ngu- H. pylori kunye nezilonda zesisu okanye esiswini. Ingathathwa njenge-20 mg yokulibaziseka-yokukhupha i-capsule kwiiveki ezi-4 ukuya kwezi-8 kubantu abadala kunye nakunyaka omnye nangaphezulu.

Ngaba i-pantoprazole kunye ne-omeprazole ziyafana?

I-Pantoprazole kunye ne-omeprazole bakudidi olunye lwamayeza. Nangona kunjalo, banokusetyenziswa okuvunyiweyo kunye neziphumo ebezingalindelekanga. Ziza ngeedosi ezahlukeneyo kunye nokwenziwa.

Ngaba i-pantoprazole okanye i-omeprazole ibhetele?

I-Pantoprazole kunye ne-omeprazole zombini ziyasebenza kwi-GERD kunye ne-esophagitis erosive. Elinye ichiza le-PPI linokukhethwa kunenye ngokuxhomekeke kwimeko yokunyangwa kunye nexabiso lonyango.

Ndingayisebenzisa i-pantoprazole okanye i-omeprazole ngelixa ndikhulelwe?

I-Pantoprazole kunye ne-omeprazole azikhuthazwa kubafazi abakhulelweyo ngenxa yomngcipheko wokonzakala kosana olungekazalwa. Nangona kunjalo, kwezinye iimeko, izibonelelo zinokudlula umngcipheko. Dibana nogqirha ukuba ukhulelwe.

Ndingayisebenzisa i-pantoprazole okanye i-omeprazole ngotywala?

Ukusela utywala kunokunyusa iziphumo ebezingalindelekanga ezithile ezinxulunyaniswa nepantoprazole okanye omeprazole. Ngenxa yokuba intloko yesifo kunye nesicaphucaphu ziyimiphumo emibi ye-PPIs, ezi ziphumo zibi kunokuba zibi xa ii-PPI zithathwa ngotywala.

Ngaba i-OTC omeprazole iyafana nommiselo?

I-omeprazole engaphezulu kwekhawuntari (i-OTC) iqulethe ichiza elifanayo kunye namandla e-omeprazole. I-OTC omeprazole inokufumaneka njenge-OTC Prilosec kunikezelo lweentsuku ezili-14 lweepilisi ezingama-20 mg. Le khosi yonyango akufuneki ithathwe ngaphezulu kwesinye kwiinyanga ezi-4.

Ngaba kufuneka ndithathe i-Pantoprazole kunye ne-Omeprazole ngaxeshanye?

I-Pantoprazole kunye ne-omeprazole akufuneki zithathwe ngaxeshanye. Basebenza ngeendlela ezifanayo ngokuvala imveliso ye-gastric acid esiswini. Ukuthatha kunye kunokunyusa umngcipheko weziphumo ezibi.