I-FDA ivuma okokuqala i-Eliquis generic: apixaban

Iindaba

Izigulana ezisemngciphekweni omkhulu wokubethwa sistroke, i-pulmonary embolism (PE), kunye ne-vein thrombosis enzulu (i-DVT) kungekudala iza kuba nenketho entsha yohlobo oluqhelekileyo lokucoca igazi. NgoDisemba 23, i-U.S (FDA) yamkelwe Izicelo ezibini zohlobo lokuqala lwe UEliquis (apixaban) iipilisi.

Yintoni uEliquis?

U-Eliquis unqabile ngegazi, utsho Nonye Uddoh , Pharm.D., Usokhemesti weklinikhi kunye ne-UnitedHealth Group, eSilver Spring, eMaryland. Isebenza ngokuthintela iproteni ekunqandayo ebizwa ngokuba yiFactor Xa. I-Factor Xa yenye yezinto ezininzi ezijiyayo egazini lethu.

Igama lophawu lweziyobisi lalikhona yavunywa okokuqala yi-FDA ngo-2012 Iza kwenziwa yiBristol-Myers Squibb kwaye ithengiswe yiPfizer. Ngelo xesha, amayeza ayelindelwe kakhulu ngoochwephesha beentliziyo ababevuya kukukwazi kwabo ukunceda abaguli abanomngcipheko othile wokunqanda igazi. U-Eliquis wayengumlomo wesithathu we-anticoagulant (igazi elincinci) ukufumana imvume ye-FDA. Nangona kunjalo, le yimvume yokuqala ye-arhente ye-Eliquis generic.

I-anticoagulants yomlomo ethe ngqo efana ne-Eliquis ithathe indawo yeyeza elibizwa ngokuba yi-Eliquis Coumadin (warfarin) Unyango oludala olufuna ukubekwa esweni ngononophelo kwaye lunonxibelelwano olunokubakho neziyobisi. Izigulana ezithatha i-Eliquis azidingi kuvavanyo lwegazi oluphindaphindiweyo, ukwenza ukuba unyango lufikeleleke ngakumbi kubantu abaninzi.IXarelto yenye into entsha nethandwayo e-Eliquis.

Ezinxulumene: Eliquis vs. Xarelto

Zeziphi iimeko ezijija igazi ezenziwa nguEliquis?

Ngokwe-FDA , Oogqirha banokumisela uEliquis ngezi zizathu zilandelayo:

• Ukunciphisa umngcipheko wokubetha kunye ne-systemic embolism kwizigulana ezine-nonvalvular atrial fibrillation.
• Ukuthintela i-vein thrombosis enzulu (i-DVT) emilenzeni, enokuthi ikhokelele kwi-pulmonary embolism (PE) emiphungeni kwizigulana ezenze i-hip okanye idolo lotshintsho.
• Ukunyanga i-DVT kunye ne-PE kunye nokunciphisa umngcipheko wokuphindaphindeka kwe-DVT kunye ne-PE kulandela unyango lokuqala.

Zonke ezi meko ziyingozi-nokuba zisongela ubomi-kwaye zonke zibandakanya amahlwili egazi.

Ukubetha kwenzeka xa kukho i-clot yegazi kwingqondo evimba ukuhamba kweoksijini ukuya kwiiseli zobuchopho, utshilo uGqirha Uddoh. Inkqubo embolisms ibangelwa kukukhula kwamahlwili egazi kwimithambo enzulu yemilenze (ebizwa ngokuba yi-DVT) okanye kwimiphunga (ebizwa ngokuba yi-PE).

I-DVT ibangela iintlungu nokudumba emlenzeni kufutshane negazi. Ukuba ishiywe inganyangwa, i-clot yegazi inokuhamba iye emiphungeni, ibangele i-PE. Le yimeko enzima kakhulu ebandakanya iimpawu ezinjengeentlungu zesifuba, ezinokuba zibi ngakumbi xa uphefumla ngokunzulu okanye ukhohlela, utyhafile, utyhafe, ukhohlela igazi, uphefumla nzulu, ukubetha kwentliziyo okukhawulezayo okanye okungaqhelekanga, kunye nokuphefumla kancinci.

I-fibrillation ye-Atrial kunye notyando oludibeneyo lokutshintsha luyonyusa umngcipheko wokubetha, i-DVT kunye ne-PE. U-Eliquis, kunye no-Eliquis generic, unokuwunciphisa loo mngcipheko.

Ezinxulumene : Ngaba kufuneka uthathe abacoci gazi kwi-AFib?

Umthatha njani uEliquis?

Ngokwe- umenzi , I-Eliquis ithathwa njenge-2.5 okanye i-5 mg tablet ngomlomo kabini yonke imihla.

Ixabisa malini uEliquis?

Izigulana zingathenga ipakethi yokuqalisa ngenkxaso yenyanga enye ye-Eliquis malunga ne- $ 531, kuxhomekeke kwikhemesti abayisebenzisayo. Nangona kunjalo, i-inshurensi ihlala igubungela uninzi lwelo xabiso. Izigulana ezineinshurensi yorhwebo zihlala zihlawula malunga ne- $ 43 ngenyanga. Icandelo lezonyango i-Medicare Part D kunye ne-Medicare Advantage zikwagubungela i-Eliquis, ukwehlisa ixabiso ukuya kuthi ga kwi-19 yeedola kuphela kwabanye abathengi.

Iya kufumaneka nini ukuthengwa kwegeneric?

Ukuvunywa kwe-FDA generic ye-Eliquis (apixaban) yaya kwiinkampani ezimbini zamachiza: iMicrosoft Labs Limited kunye neMylan Pharmaceuticals, Inc. Nangona kunjalo, ezi nkampani zimbini azikabhengezi ukuba ukuthengisa kwe-US kuya kuqala nini. Amaxabiso aqhelekileyo awakafumaneki.