Eyona >> Iziyobisi Vs. Umhlobo >> I-Shingrix vs.Zostavax: Umahluko, ukufana, kwaye kukuphi okungcono kuwe

I-Shingrix vs.Zostavax: Umahluko, ukufana, kwaye kukuphi okungcono kuwe

Iziyobisi Vs. Umhlobo

Okwangoku zimbini izitofu zokugonya ezinokunikwa ukunqanda i-herpes zoster, eyaziwa njenge-shingles: iShingrix kunye neZostavax. Isitofu sokugonya i-shingles siyacetyiswa kubantu abadala xa sele beneminyaka engama-50.

Uninzi lwabantu lusulelwe yintsholongwane ye-varicella zoster ukuba bakhe babanerhashalala. Emva kwesisombululo se-chickenpox, intsholongwane ye-varicella zoster ilele emzimbeni iminyaka, ukuba ayingonaphakade. Emva kwexesha ebomini, intsholongwane iyakwazi ukuphinda isebenze njengamaqhina kwaye ibangele irhashalala ebuhlungu edla ngokusongela ubuso okanye umzimba.

Nangona iShingrix kunye neZostavax basebenza ngeendlela ezifanayo zokuthintela i-shingles, kukho umahluko obalulekileyo phakathi kwezi zimbini.

Yintoni umahluko ophambili phakathi kweShingrix kunye neZostavax?

I-Shingrix (Yintoni i-Shingrix?) Sisixhobo sokugonya esenziwe ngokutsha, esixhonyiweyo esaqala ukuvunywa yi-FDA ngo-2017. Sisebenzisa i-varicella-zoster glycoprotein E antigen ukuvelisa amajoni omzimba emzimbeni. Isincedisi, okanye isithako esongeziweyo, sinceda ukukhulisa impendulo yomzimba yokuzikhusela kwintsholongwane. Ngenxa yokuba i-Shingrix isitofu sokugonya esingasebenziyo, inokusetyenziswa kwizigulana ezingafakwanga emzimbeni okanye abo banamajoni omzimba abuthathaka.

I-Shingrix ilawulwa njenge-injection kwi-muscle (intramuscular). Inikwa ngamanani amabini ahlukeneyo kunye nexesha iinyanga ezimbini ukuya kwezintandathu esiphakathini. Ithamo lesibini liyimfuneko ukuqinisekisa ukusebenza kwexesha elide.

I-Zostavax, evunyiweyo ngo-2006, sisixhobo sokugonya se-herpes zoster. Ngamanye amagama, iZostavax inenguqu ebuthathaka yentsholongwane yokwenyani ukuvelisa impendulo yomzimba. Ngesi sizathu, ayikhuthazwa into yokuba ungafakwanga emzimbeni. Okanye, isitofu sokugonya ngokwaso sinokubangela usulelo.

I-Zostavax ilawulwa njengenaliti enye phantsi kolusu (ongama). Iza kwifayile ye- inguqulelo engumkhenkce kunye Uhlobo oluzinzileyo lwefriji . Inguqulelo engumkhenkce kufuneka igcinwe emkhenkceni ngexesha lothutho kunye nokugcinwa kwayo ukuze kuqinisekiswe ukusebenza kwayo ngelixa i-Zostavax ezinzileyo efrijini ingagcinwa kwifriji ide ifune ukusetyenziswa.

Umahluko ophambili phakathi kweShingrix kunye neZostavax
	I-Shingrix	Zostavax
Iklasi yeziyobisi	Ugonyo	Ugonyo
Uhlobo lweBrith / generic	Igama lebrand kuphela	Igama lebrand kuphela
Ngubani igama eliqhelekileyo?	Zoster Vaccine Recombinant, Uncedisile	Zoster Vaccine Live usetyenziso lweWindows kwi- Ivenkile yeWindows
Zeziphi iifom eza nalo iziyobisi?	Ukurhoxiswa kwenaliti yemisipha	Ukurhoxiswa kwenaliti engaphantsi
Ithini idosi esemgangathweni?	Lawula idosi e-1 (0.5 ml) kunye nenye idosi (0.5 ml) phakathi kweenyanga ezi-2 ukuya kwezi-6 kamva	Ukulawula idosi enye (0.65 ml) kube kanye
Lude kangakanani unyango oluqhelekileyo?	Ukugonywa kugqityiwe kwiinyanga ezi-2 ukuya kwezi-6 emva kwedosi ezimbini	Ugonyo lugqityiwe emva kwethamo elinye
Ngubani oqhelekileyo usebenzisa amayeza?	Abantu abadala abaneminyaka engama-50 ubudala nangaphezulu	Abantu abadala abaneminyaka engama-50 ubudala nangaphezulu

Iimeko eziphathwe nguShingrix kunye noZostavax

I-Shingrix kunye ne-Zostavax yi-FDA evunyiweyo ukukhusela i-shingles (herpes zoster). Omabini la machiza abonakalisiwe ukukhusela i-shingles kubantu abadala abaneminyaka engama-50 nangaphezulu. I-Shingrix kunye ne-Zostavax azisetyenziswanga ukuthintela usulelo lwe-varicella ephambili, ekwabizwa ngokuba yirhashalala.

I-postherpetic neuralgia luhlobo oluqhelekileyo lweentlungu zentliziyo eziphakama nge-shingles. Ngenxa yokuba i-Shingrix kunye ne-Zostavax inokuthintela i-shingles, banokuthintela i-postherpetic neuralgia (PHN) kunye nezinye iingxaki ezibuhlungu ezivela kwi-shingles. Nangona kunjalo, ezi zitofu azibhalwanga ukuba zinyange i-PHN.

Imeko	I-Shingrix	Zostavax
Uthintelo lwe-herpes zoster (shingles)	Ewe	Ewe

Ngaba iShingrix okanye iZostavax isebenza ngakumbi?

I-Shingrix kunye ne-Zostavax bobabini baqinisekisiwe ukuthintela i-shingles. Nangona kunjalo, i-Shingrix sisitofu sokugonya esitsha esigqalwa njengesisebenza ngakumbi kune-Zostavax. I-Shingrix iyacetyiswa nakwabo sele befumene isitofu sokugonya se-Zostavax ngaphambili.

Uvavanyo lwezonyango lubonakalisile ukuba uShingrix I-97% iyasebenza ekuthinteleni i-shingles kubantu abadala abaneminyaka engama-50 ukuya kwengama-69 ubudala. I-Shingrix iyasebenza ekuthinteleni i-shingles kubantu abadala-abantu abadala ngaphezulu kwe-70 iminyaka, i-Shingrix I-91% iyasebenza .

IZostavax ine Ukusebenza kwe-70% izinga lokuthintela i-shingles kubantu abadala abaneminyaka engama-50 ukuya kwengama-69 ubudala, ngokweZoster Efficacy and Safety Trial (ZEST). Iziphumo ezivela kwi- Isifundo soThintelo loShingles ibonise ukuba iZostavax ingama-51% esebenzayo xa kuthelekiswa neesling. Xa kuthelekiswa neShingrix, ukusebenza kweZostavax kuyancipha kumaqela amadala. Ngokusekwe kwiziphumo ze-SPS, iZostavax ingama-64% esebenzayo kubantu abadala abaneminyaka engama-60 ukuya kwengama-69 ubudala; I-41% isebenza kubantu abadala abaneminyaka engama-70 ukuya kuma-79 ubudala; kunye ne-18% esebenzayo kubantu abadala abaneminyaka engama-80 nangaphezulu.

Umboneleli wakho wezempilo uya kuthi acebise uShingrix ngaphezulu kweZostavax. I-Shingrix icetyiswa ngakumbi kwizigulana ezingafakwanga emzimbeni ngenxa yokuba isitofu sokugonya esingaphiliyo. Buza ugqirha wakho okanye usokhemesti malunga nokuba yeyiphi iyeza lokugonya le-shingles elilungele wena.

Umyinge kunye neendleko zokuthelekisa iShingrix vs.Zostavax

Kubantu abadala abaneminyaka engama-50 nangaphezulu, zizicwangciso kuphela kunye ne-Medicare Icandelo D lokugubungela iya kugubungela isitofu sokugonya seShingrix. Nangona kunjalo, kusenokubakho ikopi kunye nokugubungela iCandelo D. Ixabiso eliphakathi lemali yedosi enye ye-Shingrix yi- $ 167, nangona usenokukwazi ukusebenzisa ikhadi lesaphulelo sokuyalela le ndleko. Jonga ikhemesti yakho ukuze ubone ukuba ungasebenzisa ikhadi le-Shingrix singleCare.

NjengoShingrix, iZostavax ikakhulu igutyungelwe zizicwangciso zeMedare yeD okanye iiplani zeMedicare zeNzuzo kunye ne-Medicare Part D yokugubungela. I-copay yeZostavax ene-inshurensi ingahluka. Ngexabiso lemali eliphakathi le- $ 278, iZostavax inokubiza nge-inshurensi okanye ngaphandle kwayo. Sebenzisa ikhadi lesaphulelo sikagqirha kwiZostavax unokukwazi ukunciphisa le ndleko.

	I-Shingrix	Zostavax
Ngokuqhelekileyo ihlawulwa yi-inshurensi?	Ewe	Ewe
Ngokuqhelekileyo ihlanganiswe yiCandelo le-Medicare?	Ewe	Ewe
Umthamo osemgangathweni	Inaliti enye (0.5 ml) kunye nenye inaliti (0.5 ml) kwiinyanga ezi-2 ukuya kwezi-6 kamva	Inaliti enye yedosi enye (0.65 ml)
I-Medicare copay eqhelekileyo	$ 0- $ 164	$ 0- $ 237
Ixabiso elilodwa	$ 155 +	N / A

Iziphumo eziqhelekileyo zeShingrix vs Zostavax

Iziphumo eziqhelekileyo ezichaphazelekayo zeShingrix kunye neZostavax zibandakanya iimpendulo kwindawo yenaliti. Emva kwenaliti yeShingrix okanye iZostavax, unokufumana iintlungu, ubomvu, okanye ukudumba ujikeleze indawo yenaliti. Unokuziva ukrakra okanye urhawuzelela ujikeleze indawo yenaliti.

Xa kuthelekiswa neZostavax, uShingrix uxelwe ukuba ubangela ukuphendula okungaphezulu kwenkqubo efana nentloko, umkhuhlane, iintlungu zemisipha (myalgia), kunye nokudinwa. Ngelixa iziphumo ebezingalindelekanga zinokukhathaza, zihlala zinobulali kwaye ziyanyamalala zodwa.

	I-Shingrix	Zostavax
Imiphumela	Iyasebenza?	Rhoqo	Iyasebenza?	Rhoqo
Ububomvu kwindawo yenaliti	Ewe	39%	Ewe	36%
Ubuhlungu kwindawo yenaliti	Ewe	86%	Ewe	3. 4%
Ukudumba kwindawo yenaliti	Ewe	29%	Ewe	26%
Ukurhawuzelela kwindawo yenaliti	Ewe	Mbini%	Ewe	7%
Intloko ebuhlungu	Ewe	Zine. Zihlanu%	Ewe	1%
Ifiva	Ewe	26%	Ewe	Mbini%
Intlungu yezihlunu	Ewe	53%	Hayi	*
Ukudinwa	Ewe	51%	Hayi	*

* akuxelwa
Ukuphindaphinda akusekelwanga kwidatha ukusuka kuvavanyo lwentloko ukuya entloko. Olu alunakuba luluhlu olupheleleyo lweziphumo ezibi ezinokwenzeka. Nceda ujonge ugqirha wakho okanye umboneleli wezempilo ukuze ufunde okungakumbi.
Umthombo: Yonke imihla (iShingrix) , Yonke imihla (iZostavax)

Ukudibana kweziyobisi kweShingrix vs.Zostavax

Amachiza omzimba wokunyanga njenge-cyclosporine kunye ne-tacrolimus anokunciphisa ukusebenza kwezitofu zokugonya. I-Steroids, njenge-prednisone, kunye ne-chemotherapy zinokuba nefuthe lokuzikhusela emzimbeni elinokuthi litshintshe indlela izitofu ezisebenza ngayo.

Abo bakunyango lwe-immunosuppressive kufuneka baphephe i-Zostavax ngokupheleleyo; I-Zostavax iqulethe intsholongwane ephilayo, enokubangela usulelo.

Amachiza antiviral anje nge-acyclovir kunye ne-famciclovir anokuphazamisana nefuthe lokugonya iZostavax. IKomiti yeeNgcebiso ngeZenzo zokuGonya (i-ACIP) icebisa ukuba abantu abakumachiza antiviral bayeke ukuthatha amayeza antiviral Iiyure ezingama-24 ngaphambili ukufumana isitofu sokugonya seZostavax. Unyango ngamachiza antiviral akufuneki luqhubeke kwakhona kwiintsuku ezili-14 emva kogonyo lweZostavax.

Iziyobisi	Iklasi yeziyobisi	I-Shingrix	Zostavax
ICclosporine ITacrolimus IPrednisone Unyango ngamayeza	Unyango lwe-Immunosuppressive	Ewe	Ewe
Icycylovir Ukuxabiseka Famciclovir	Iiarhente zentsholongwane	Hayi	Ewe

Nxibelelana noochwephesha kwezolunye unxibelelwano olunokubakho ngeziyobisi

Izilumkiso zikaShingrix kunye noZostavax

I-Shingrix kunye ne-Zostavax zinokubangela i-hypersensitivity, okanye i-allergen, ukusabela kwabo banezinto ezibangela ukwaliwa kukuthintela izithako. I-Zostavax inokubangela ukungabikho komzimba kubantu abanokungabikho komzimba kwi-gelatin okanye i-neomycin. Ukuphendula okungafunekiyo komzimba kunokukhokelela kukungxamiseka okukhulu kunye nengxaki yokuphefumla (anaphylaxis).

I-Zostavax kufuneka ithintelwe kwabo bathatha ii-immunosuppressive agents kunye nabo bachaphazeleka ziimeko zonyango ezenza buthathaka amajoni omzimba.

Buza ugqirha wakho okanye usokhemesti malunga nezinye izilumkiso ngaphambi kokufumana isitofu sokugonya i-shingles.

Imibuzo ebuzwa rhoqo malunga neShingrix vs Zostavax

Yintoni iShingrix?

I-Shingrix yi iyeza lokuzikhusela esetyenziselwa ukuthintela i-herpes zoster, okanye i-shingles, kubantu abadala abaneminyaka engama-50 okanye ngaphezulu. Ukuvunywa ngo-2017, iShingrix isitofu sokugonya esingasebenziyo esingenayo intsholongwane ye-varicella zoster. Inikwa ngeedosi ezimbini ezineenyanga ezimbini ukuya kwezintandathu phakathi kwethamo lokuqala kunye nedosi yesibini. I-Shingrix yenziwa nguGlaxoSmithKline.

Yintoni iZostavax?

I-Zostavax sisixhobo sokugonya se-zoster esiphilayo esaye savunywa nge-FDA ngo-2006. I-Zostavax ilawulwa kwidosi enye kubantu abadala abaneminyaka engama-50 okanye ngaphezulu. Yenziwe nguMerck.

Ngaba iShingrix kunye neZostavax ziyafana?

Zombini i-Shingrix kunye ne-Zostavax zinokunciphisa umngcipheko we-shingles. Nangona kunjalo, bahlukile ngokusebenza, kulawulo, kunye nakwimiphumo emibi. I-Shingrix yisitofu sokugonya se-zoster kwaye iZostavax sisigonyo esiphilayo. Intsingiselo, i-Shingrix iqulethe uhlobo olungasebenziyo lwegciwane le-varicella-zoster kwaye iZostavax iqulethe indlela ephilileyo, ebuthathaka yentsholongwane. Omnye umahluko kukuba iShingrix itofelwe kwimisipha ngelixa iZostavax itofelwe phantsi kolusu. Xa kuthelekiswa neZostavax, i-Shingrix ligonyo elitsha le-shingles.

Ngaba iShingrix okanye iZostavax ibhetele?

I-Shingrix isebenza ngakumbi kuneZostavax. I-Shingrix i-97% iyasebenza ekuthinteleni i-shingles kubantu abadala abaneminyaka engama-50 ukuya kwengama-69 ubudala ngelixa iZostavax isebenza kuphela ngama-70% ekuthinteleni i-shingles kwiqela elifanayo. I-Shingrix ihlala ithintela i-shingles kubantu abadala xa ukusebenza kwe-Zostavax kuncipha ngokukhula kweminyaka. Nangona kunjalo, i-Shingrix ineziphumo ebezingalindelekanga kune-Zostavax.

Ngaba ndingasebenzisa iShingrix okanye iZostavax ngelixa ndikhulelwe?

Amaziko oLawulo lweNtsholongwane kunye noThintelo (CDC) akacebisi iShingrix okanye iZostavax kwabasetyhini abakhulelweyo. Akukho zifundo zaneleyo ukumisela ukhuseleko lweShingrix okanye I-Zostavax kwabasetyhini abakhulelweyo . Qhagamshelana nogqirha wakho okanye umboneleli wezempilo ngaphambi kokufumana isitofu sokugonya i-shingles.

Ndingayisebenzisa iShingrix okanye iZostavax ngotywala?

Ukusela utywala akutshintshi ukusebenza kweShingrix okanye iZostavax. Kukhuselekile ngokubanzi ukusela ngokumodareyitha emva kokugonywa ngesitofu sokugonya i-shingles.

Uhlala ixesha elingakanani ugonyo lwe-Shingrix?

Uvavanyo lwezonyango lubonakalisile ukuba uShingrix ihlala isebenza iminyaka emine ubuncinci emva kwedosi yesibini. Kucetyiswa ukuba i-Shingrix ihlala ixesha elide kunoko. Okwangoku, ezinye izifundo zisaqhutywa ngokusebenza kweShingrix ixesha elide.

Zostavax isebenza ixesha elingakanani?

Ukukhuselwa kwi-shingles kuhlala kujikeleze kweminyaka emihlanu emva kogonyo `` Zostavax '' . Emva kweminyaka emihlanu, ukusebenza kweZostavax kunokuhla ngokuhamba kwexesha. I-CDC icebisa ukufumana iyeza elitsha le-shingles, i-Shingrix, nokuba sele ufumene isitofu sokugonya se-Zostavax ngaphambili.

Kwenzeka ntoni ukuba awufumani Shingrix yesibini?

Ukudubula kwesibini kwe-Shingrix kubalulekile ukuqinisekisa ukhuseleko olupheleleyo ngesitofu sokugonya. Nangona kunjalo, awudingi ukuba nexhala ukuba ngaphezulu kweenyanga ezintandathu zidlulile ngaphambi kokuba ufumane i-booster shot. Qinisekisa ukuba ufumana umpu wesibini kufutshane neenyanga ezimbini ukuya kwezintandathu ngexesha elibekiweyo.