Eyona >> Iziyobisi Vs. Umhlobo >> I-Tramadol vs.Hydrocodone: Umahluko, ukufana, kwaye yeyiphi efanelekileyo kuwe

I-Tramadol vs.Hydrocodone: Umahluko, ukufana, kwaye yeyiphi efanelekileyo kuwe

Iziyobisi Vs. Umhlobo

I-Tramadol kunye ne-hydrocodone ngamayeza amabini asetyenziselwa ukunyanga iintlungu ezingakhululekanga ngokulula nge-analgesic engeyiyo-opioid. Omabini la mayeza anokunyanga iintlungu eziphakathi ukuya koxinzelelo emva kotyando okanye kwiimeko ezingapheliyo ezifana nomhlaza. Nangona kunjalo, kwiimeko ezininzi zentlungu, unyango lwe-non-opioid luhlala luzanywa kuqala.

Zombini i-tramado l kunye ne-hydrocodone zisebenza ngokuzibophelela kwii-opioid receptors ukutshintsha indlela umntu aphendula ngayo kwintlungu. Njengama-opioid kagqirha, zinamandla ngaphezu kwe-avareji yokunciphisa iintlungu. Ke ngoko, la machiza afuna utyelelo kugqirha ukuvavanya iintlungu zakho.

Nguwuphi umahluko ophambili phakathi kweTramadol kunye neHydrocodone?

I-Tramadol ligama elenziwe lafana ne-Ultram, Ultram ER, kunye neConZip. Sishedyuli IV ye-narcotic ngokwe-DEA ethetha ukuba inokubakho ukuxhatshazwa. Ngelixa ibophelela kwii-opioid receptors, inokwandisa umsebenzi wezinye i-neurotransmitters zengqondo ezinje nge-norepinephrine kunye ne-serotonin.

IHydrocodone ligama elenziwa lafana neZohydro ER kunye neHysingla ER. I-Hydrocodone ithathwa njengecwecwe lokudibanisa kunye ne-acetaminophen phantsi kwegama lophawu lweVicodin okanye iLortab. Ngokungafaniyo ne-tramadol, i-hydrocodone sishedyuli II yeyeza elilawulwa yi-DEA elinomngcipheko ophezulu wokuphathwa gadalala.

Umahluko ophambili phakathi kweTramadol kunye neHydrocodone
	I-Tramadol	IHydrocodone
Iklasi yeziyobisi	I-Opioid	I-Opioid
Uhlobo lweBrith / generic	Inguqulelo yesiqhelo iyafumaneka	Inguqulelo yesiqhelo iyafumaneka
Ngubani igama eliqhelekileyo? Ngubani igama lophawu?	Isizukulwana: iTramadol Igama lebrand: Ultram, Ultram ER	Isizukulwana: IHydrocodone Igama lebrand: Zohydro ER, Hysingla ER, Vicodin (edityaniswe ne-acetaminophen), iLortab (edityaniswe ne-acetaminophen), iNorco (edityaniswe ne-acetaminophen)
Zeziphi iifom eza nalo iziyobisi?	Ithebhulethi yomlomo Ithebhulethi yomlomo, ukukhutshwa okwandisiweyo Iifomsile zomlomo Ukurhoxiswa ngomlomo	Ithebhulethi yomlomo Ithebhulethi yomlomo, ukukhutshwa okwandisiweyo Iifomsile zomlomo Isisombululo somlomo
Ithini idosi esemgangathweni?	I-Ultram: 50 ukuya kwi-100 mg zonke iiyure ezi-4 ukuya kwezi-6 njengoko kufuneka I-Ultram ER: 100 mg rhoqo kwiiyure ezingama-24	I-Zohydro ER: 10 mg rhoqo kwiiyure ezili-12 IHysingla ER: 20 mg rhoqo kwiiyure ezingama-24 IVicodin, iLortab, iNorco (ngokudityaniswa ne-acetaminophen): 5 ukuya kwi-10 mg zonke iiyure ezi-4 ukuya kwezi-6 njengoko kufuneka
Lude kangakanani unyango oluqhelekileyo?	Yonke imihla njengoko kufuneka. Ixesha lonyango lixhomekeke kumyalelo kagqirha wakho.	Yonke imihla njengoko kufuneka. Ixesha lonyango lixhomekeke kumyalelo kagqirha wakho.
Ngubani oqhelekileyo usebenzisa amayeza?	Abantu abadala abaneminyaka eli-18 nangaphezulu	Abantu abadala abaneminyaka eli-18 nangaphezulu

Iimeko zonyango lweTramadol kunye neHydrocodone

I-Tramadol kunye ne-hydrocodone zombini zibonisiwe kulawulo lweentlungu. Zihlala zichazwe ukuba une-moderation ukuya kwiintlungu ezingapheliyo, ngakumbi kwiimeko ezinje ngomhlaza. Omabini la mayeza ahlala esetyenziselwa iintlungu emva kokulimala kunye nokuhlinzwa.

Imeko	I-Tramadol	IHydrocodone
Ukumodareyitha kwiintlungu ezibuhlungu	Ewe	Ewe
Intlungu engapheliyo	Ewe	Ewe
Ubuhlungu bokulimala okanye emva kotyando	Ewe	Ewe
Umhlaza Ubuhlungu	Ewe	Ewe

Ngaba iTramadol okanye iHydrocodone isebenza ngakumbi?

I-Tramadol kunye ne-hydrocodone zombini zisebenza kakuhle kwi-opioids yentlungu. Kukho izifundo ezininzi ngokuthelekisa ukusebenza kwazo. Ngenxa yokuba i-hydrocodone sisiCwangciso II se-opiate, inokuqwalaselwa njengeyona inamandla nangona iza namandla aphezulu okuphathwa gadalala. I-Tramadol inokuba nesiphumo esisezantsi sokuxhatshazwa kunye neziphumo ebezingalindelekanga eziqinisekileyo.

Ngenye Ukufunda ngokubanzi , I-tramadol ene-acetaminophen ithelekiswa ne-hydrocodone ene-acetaminophen kwizigulana ezifumana iintlungu kwi-ankle sprain. Izigulana ezingama-400 zahlulwa zangamaqela amabini zifumana ichiza elinye okanye elinye. Iziphumo zafumanisa ukuba omabini amayeza abonelela ngentlungu yokuthelekisa kwiiyure ezine xa kuthelekiswa ne-placebo.

Kwenye ulingo lwezonyango , I-hydrocodone ene-acetaminophen ithelekiswa ne-tramadol kwizigulana ezingama-68. Aba baguli babefike kwisebe likaxakeka ngenxa yeentlungu zomisipha kumalungu abo, amathambo, okanye izihlunu. Iziphumo zafumanisa ukuba i-hydrocodone ene-acetaminophen ibonelela ngesiqabu sentlungu xa kuthelekiswa ne-tramadol esekwe kumanqaku eentlungu ezinesikali se-analog ebonakalayo (VAS).

Kwi ityala elingaboni kabini , I-hydrocodone ene-acetaminophen yafaniswa ne-tramadol kwizigulana ezili-118 ezineentlungu ezingapheliyo zomhlaza. I-Tramadol ibonise ukukhululeka kwintlungu kwi-62% yezigulana xa kuthelekiswa ne-56.5% yezigulana ezine-hydrocodone. Nangona kunjalo, ukukhululeka kwentlungu kwakufana kuwo omabini amaqela. I-Tramadol ikwafunyanwa ukuvelisa iziphumo ebezingalindelekanga ezinobunzima xa kuthelekiswa nehydrocodone.

Nokuba umiselwe i-tramadol okanye i-hydrocodone ixhomekeke kakhulu kwinqanaba leentlungu zakho. Xa uvavanya iintlungu zakho, ugqirha wakho uya kujonga imbali yakho yonyango epheleleyo, nayiphi na imbali yokusetyenziswa gwenxa kweziyobisi, kunye nawaphi na amayeza anokubangela ukuhlangana kweziyobisi. Ke ngoko, amayeza eentlungu ahlukaniswe ngokukodwa kwaye afuna ukubonisana nogqirha ukufumanisa ukuba yeyiphi eya kusebenza ngakumbi kuwe.

Ukufunyanwa kunye nokuthelekiswa kweendleko zeTramadol vs.Hydrocodone

I-Tramadol iyafumaneka njengechiza elenziwe lafana nelo lenziwe ngumenzi. Ngokuqhelekileyo ihlanganiswe yi-Medicare kunye neeplani ezininzi ze-inshurensi. Ixabiso eliphakathi lokubonelela ngeepilisi ze-tramadol ezingama-60 mg zijikeleze i-40 yeedola. Ugcina ngakumbi nge-singleCare coupon ye-generic tramadol kwikhemesti yakho yasekuhlaleni.

IHydrocodone sisiyobisi esenziwa gabalala esihlala sigutyungelwa yiMedicare kwaye uninzi lwezicwangciso zeinshurensi. Ixabiso lehydrocodone liyahluka phakathi kwezicwangciso zeinshurensi ezahlukeneyo. INorco equlathe ihydrocodone kunye neacetaminophen inokuqhuba ngexabiso eliphakathi le- $ 317. Ngeponi enye ye-SingleCare, unokulindela ukugcina ngaphezulu kugqirha we-hydrocodone ene-acetaminophen.

	I-Tramadol	IHydrocodone
Ngokuqhelekileyo ihlawulwa yi-inshurensi?	Ewe	Ewe
Ngokuqhelekileyo igutyungelwe yiMedicare?	Ewe	Ewe
Umthamo osemgangathweni	Iipilisi ezingama-50 mg (ukubonelelwa ngama-60) Kuxhomekeke kumyalelo kagqirha wakho	Iipilisi ezi-5-325 mg (ukubonelelwa nge-100) Kuxhomekeke kumyalelo kagqirha wakho
I-Medicare copay eqhelekileyo	$ 40	$ 317
Ixabiso elilodwa	$ 15	$ 18

Iziphumo eziqhelekileyo ezichaphazela iTramadol kunye neHydrocodone

I-Tramadol kunye ne-hydrocodone kunokubangela iziphumo ezifanayo. Ngenxa yokuba zombini zichaphazela inkqubo ye-nervous system (CNS), zinokubangela ukuba nesiyezi, ukulala nokudinwa. La mayeza anokubangela iziphumo ebezingalindelekanga zesisu njengokuqunjelwa okanye isisu esibuhlungu. Isihlunu, ukugabha, umlomo owomileyo, kunye nentloko zezinye iziphumo ebezingalindelekanga ekwabelwana ngazo.

I-Tramadol inokubangela urhudo, ukugaya ukutya kunye nokubila kwabanye abantu. Ngakolunye uhlangothi, i-hydrocodone inokubangela ukuba i-fluid buildup (edema) okanye i-spasms ye-muscle kwabanye abantu. Ngokubanzi, iziphumo ebezingalindelekanga eziqhelekileyo zinokudibana phakathi kwala machiza mabini kuba bekwiklasi enye.

Ezinye izinto ezinqabileyo kodwa ezinobuzaza ze-tramadol kunye ne-hydrocodone zinokubandakanya uxinzelelo, uxinzelelo, okanye olunye uphazamiseko lwengqondo. Ukuphendula ngokuchaseneyo kunokwenzeka kwaye kunokubandakanya ukukhawuleza, ukuxubha kunye nentlungu yesifuba.

	I-Tramadol	IHydrocodone
Imiphumela	Iyasebenza?	Rhoqo	Iyasebenza?	Rhoqo
Ukuqunjelwa	Ewe	24-46%	Ewe	Shumi elinanye%
Ukuba nesiyezi	Ewe	26-33%	Ewe	3%
Isicaphucaphu	Ewe	24-40%	Ewe	10%
Intloko ebuhlungu	Ewe	18-32%	Ewe	4%
Ukozela	Ewe	16-25%	Ewe	5%
Ukuhlanza	Ewe	9-17%	Ewe	3%
Ukurhawuzelela (Pruritus)	Ewe	8-11%	Ewe	3%
Ubuthathaka	Ewe	6-12%	Ewe	4%
Ukubila	Ewe	6-9%	Hayi	-
Ukutya	Ewe	5-13%	Hayi	-
Umlomo owomileyo	Ewe	5-10%	Ewe	3%
Urhudo	Ewe	5-10%	Hayi	-
Edema	Hayi	-	Ewe	1%
Usulelo lokuphefumula	Hayi	-	Ewe	1%
Ukudumba kwezihlunu	Hayi	-	Ewe	1%
Umqolo obuhlungu	Hayi	-	Ewe	1%

Dibana nogqirha okanye usokhemisti ngazo zonke iziphumo ebezingalindelekanga ezinokubakho.

Umthombo: Yonke imihla (iTramadol HCl) , Yonke imihla (iZohydro ER) .

Ukudibana kweziyobisi kweTramadol vs.Hydrocodone

I-Tramadol kunye ne-hydrocodone zinonxibelelwano olufanayo namanye amachiza. Ngenxa yokuba zixutywe esibindini, zihlala zinxibelelana nezinye iziyobisi ezichaphazela ii-enzyme zesibindi.

Iziyobisi ezithintela i-CYP3A4 kunye ne-CYP2D6 enzyme zesibindi zibandakanya i-erythromycin, ketoconazole, kunye ne-ritonavir enokunyusa inqanaba le-opioids emzimbeni kunye nokunyusa umngcipheko weziphumo ebezingalindelekanga. Iziyobisi ezenza i-CYP3A4 i-enzyme zesibindi zibandakanya i-carbamazepine kunye ne-phenytoin enokunciphisa inqanaba leeopioid emzimbeni kunye nokunciphisa ukusebenza kwayo.

I-Tramadol kunye ne-hydrocodone zinokunxibelelana nezinye iziyobisi ezineziphumo ebezingalindelekanga ze-CNS. Ezi ntlobo zeziyobisi zibandakanya i-anti-depressants, i-anticonvulsants, i-benzodiazepines, izihlaziyi zezihlunu, nezinye ezininzi. Ukuthatha ii-opioids kunye ne-anti-depressants ezonyusa i-serotonin kunokunyusa umngcipheko we-serotonin syndrome, imeko enzima efuna unyango olukhawulezileyo.

Ngokwelebheli yeziyobisi ye-FDA, i-tramadol nayo inokusebenzisana ne-digoxin kunye ne-warfarin. Iingxelo zifumene iimeko ezinqabileyo ze-digoxin ityhefu kunye neziphumo eziguqulweyo zemfazwe. Ilebheli ye-FDA ye-hydrocodone ikwakhankanya ukuba i-laxatives eyomeleleyo inokunciphisa iziphumo ze-hydrocodone emzimbeni.

Akukhuthazwa ukusela utywala ngelixa usebenzisa i-opioids. Utywala bunokudibanisa iziphumo ebezingalindelekanga ze-opioid ezinje ukozela kunye nesiyezi.

Iziyobisi	Iklasi yeziyobisi	I-Tramadol	IHydrocodone
Erythromycin Clarithromycin I-Telithromycin Rifampin	Zintsholongwane	Ewe	Ewe
Ketoconazole Itraconazole	Iarhente yokubola	Ewe	Ewe
Ritonavir Atazanavir IDarunavir Indinavir Lopinavir Saquinavir	Ukuthintela ukuthintela	Ewe	Ewe
IPhenytoin ICarbamazepine	I-Anticonvulsant	Ewe	Ewe
I-Escitalopram IFluoxetine Paroxetine Sertraline Citalopram	Ukukhetha i-serotonin reuptake inhibitor (SSRI) yoxinzelelo	Ewe	Ewe
IVenlafaxine Imilnacipran Duloxetine I-Desvenlafaxine	ISerotonin-norepinephrine reuptake inhibitor (SSNRI) yoxinzelelo	Ewe	Ewe
Doxepin Amitriptyline Clomipramine Desipramine Imipramine Umgca weNortriptyline	I-TCA yoxinzelelo	Ewe	Ewe
INaratriptan Rizatriptan ISumatriptan Zolmitriptan	I-Triptan	Ewe	Ewe
IAlprazolam IClonazepam Diazepam ILorazepam	Benzodiazepine	Ewe	Ewe
I-Rasagiline Isocarboxazid IPhenelzine Selegiline I-Tranylcypromine	I-Monoamine oxidase inhibitor (MAOI)	Ewe	Ewe
ICyclobenzaprine Imetaxalone	Izihlunu ziyaphumla	Ewe	Ewe
Lactulose	I-laxative eyomeleleyo	Hayi	Ewe
I-Digoxin	Iglycoside yentliziyo	Ewe	Hayi
IWarfarin	I-Anticoagulant	Ewe	Hayi

* Olu alunakuba luluhlu olupheleleyo lwazo zonke izinto ezinokubakho xa kusenziwa iziyobisi. Dibana nogqirha nawo onke amayeza onokuthi uwathathe.

Izilumkiso zeTramadol kunye neHydrocodone

I-Tramadol kunye nehydrocodone zithwala isilumkiso sokulutha kunye nokuxhatshazwa ukuba ayisetyenziswanga njengoko kumiselwe. Umlutha ungakhokelela ekuxhomekekeni komzimba okunokubangela iimpawu zokurhoxa ukuba iyeza limisiwe ngaso nasiphi na isizathu. Iimpawu zokurhoxa zinokubandakanya unxunguphalo, ukuqaqanjelwa sisisu kunye nokuphazamiseka.

Ukuthatha ngaphezulu kwedosi emiselweyo yeeopioid kunokunyusa umngcipheko wokudlula ngaphezulu, isiqaqa kunye nokufa. Iziphumo ezisongela ubomi ezinje ngoxinzelelo olukhulu lokuphefumla kunye nokulala kunokubakho ngokudlula. Ngesi sizathu, ii-opioids azikhuthazwa kubantwana ngenxa yomngcipheko okhulayo iingxaki zokuphefumla kunye nokufa .

Akucetyiswa ukuba usele utywala okanye uthathe ezinye iziyobisi ze-CNS nge-opioids. Kungenxa yokuba bonyusa umngcipheko weziphumo ze-CNS ezinje ngokuthamba, ukuphefumla kancinci, ikhoma kunye nokufa. Nangona idatha efunekayo, intsha uphando icebisa ukuba i-tramadol inokuba semngciphekweni omkhulu wokufa xa kuthelekiswa namayeza okulwa nokudumba.

Zombini i-tramadol kunye ne-hydrocodone zikudidi lokukhulelwa C. Ke ngoko, azicetyiswa ngokwesiqhelo kwabasetyhini abakhulelweyo okanye abancancisayo ngenxa yomngcipheko wokonzakala kosana olungekazalwa. Funa ingcebiso kwezonyango ukuba ukhulelwe okanye uceba ukukhulelwa.

Imibuzo ebuzwa rhoqo malunga neTramadol kunye neHydrocodone

Yintoni i-tramadol?

I-Tramadol sisiyobisi se-opioid esisetyenziselwa ukunyanga iintlungu eziphakathi. Sisiyobisi seShedyuli IV esifuna amayeza kunye novavanyo lwentlungu ngugqirha. Iyafumaneka kukhululo olukhawulezileyo kunye nefomu ekhutshiweyo yokuxhomekeka kubunzima bentlungu.

Yintoni ihydrocodone?

IHydrocodone lunyango lweopioid olunokunyanga iintlungu eziphakathi ukuya kwiintlungu. Sisiyobisi seShedyuli II esinokubanamandla aphezulu okuphathwa gadalala kunye nokuxhomekeka. Itholakala kwifom yokukhululwa eyandisiweyo kunye nepilisi yokudibanisa ne-acetaminophen.

Ngaba i-tramadol kunye ne-hydrocodone ziyafana?

Nangona zombini ezi opioids, tramadol kunye hydrocodone azifani. Banokusetyenziswa okufanayo kuxhomekeke kwintlungu ohlangabezana nayo. Kodwa zikwakhona ngeendlela ezahlukeneyo zedosi kwaye zineziphumo ebezingalindelekanga ezahlukeneyo kunye nokunxibelelana kweziyobisi.

Ngaba i-tramadol okanye i-hydrocodone ingcono?

Uphononongo lubonisa ukuba i-tramadol kunye ne-hydrocodone zombini ziyasebenza ngokuthelekisa iintlungu. Ezinye iingxelo zibonisa ukuba i-tramadol ineziphumo ebezingalunganga xa kuthelekiswa ne-hydrocodone. Nangona kunjalo, olunye uphononongo lubonisa ukuba i-hydrocodone inamandla ngakumbi kwaye ivelisa ukuphumla kwintlungu kwabanye abantu.

Ngaba i-tramadol yomelele kune-codeine?

Zombini i-tramadol kunye necodeine zinokuthomalalisa iintlungu kwaye zombini zithathwa njengee-opioids ezibuthathaka. Nangona kunjalo, banokwahluka kwiziphumo ebezingalindelekanga kunye nokusetyenziswa kwazo. Ngokungafaniyo ne-tramadol, i-codeine inokusetyenziswa njenge-suppressant suppressant.

Ngaba i-tramadol yi-opiate?

Ewe. I-Tramadol sisiyobisi se-opiate. Yenziwe ngokwenziwa kwaye ikwiklasi enye yeziyobisi njengezinye iintlungu ze-opioid. Njengesiyobisi seShedyuli IV, sinokubanakho ukuxhatshazwa kunye nokuxhomekeka xa kuthelekiswa nezinye i-opioids.