I-Creatinine: Uvavanyo lwegazi, uluhlu oluqhelekileyo, kunye nendlela yokunciphisa amanqanaba

Imfundo yezeMpilo

Ukwiimayile ezimbini zemva kwemini, okanye unika amandla kuseto lwesithathu ebhentshini, okanye ukhwela ibhayisekile ekukhuphukeni kuhambo lwakho lwemihla ngemihla. Uphefumla ngokukhawuleza, kwaye izihlunu zakho zisemlilweni. Umbilo uvuza isilevu sakho. Ubushushu buhlikihla izidlele zakho. Kwaye xa ugqibile, akukho nto iziva ingcono kuneshawa eshushu, iglasi yamanzi abandayo, kunye nesihlalo esofeni.

Njengabantu abaninzi, uyazi kakuhle indlela umzimba owenza ngayo umzimba wakho zive— ukuphefumla, ukubila nobushushu. Usenokude uchume kuyo. Kodwa kuninzi okungakumbi okuqhubekayo phantsi komphezulu. Xa izihlunu zakho ziqhekeka ngexesha lokuzilolonga, ziyakhula kancinci, zonyusa ubunzima bemisipha, kodwa le nkqubo ikhupha imveliso yenkunkuma egazini lakho, ikakhulu i-creatinine.

Nangona kunokuba yinto yokugqibela ocinga ngayo ngelixa ubeka iikhilomitha zakho okanye ukushaya i-rep-max max, amanqanaba akho e-creatinine egazi angabonakalisa isalathisi sempilo yakho yezintso kunye nokusebenza kwezintso.

Yintoni i-creatinine?

Wonke umntu unamanqanaba athile e-serum creatinine egazini labo. I-Creatinine yimveliso yendalo yokusetyenziswa kwemisipha, ebangelwa kukonakala kwemichiza ebizwa ngokuba yindalo. I-Creatinine ngokwayo ayinalo umsebenzi othile womzimba-yinto nje yenkunkuma. Ihlala nje egazini de ifike kwizintso, apho ihluzwa kwaye isuswe ngokuchama.

Ke, umzimba wakho uyivelisa njani i-creatinine? Iqala ngokudalwa, edityaniswe kwizintso, iipancreas, kunye nesibindi, emva koko zihanjiswe ngokuhamba kwegazi kwaye zigcinwe kwimisipha yakho yamathambo. Ngexesha lokuzikhandla, izihlunu zakho ziguqula amandla okwenza amandla, ancedisa kuthambo lomsipha. Emva kokusebenzela injongo yayo, i-creatine iba yi-creatinine kwaye iphinde ingene kwigazi elisendleleni eya kwizintso.

Nangona i-creatinine ingazuzi (okanye yonakalise) umzimba wakho, isixa se-creatinine egazini lakho sinokulinganiswa ukuvavanya impilo yakho yezintso. Ngesi sizathu, oogqirha baya kuhlala besebenzisa uvavanyo lwe-creatinine- kunye nolunye uvavanyo lwelebhu, njengovavanyo lwe-urea nitrogen (BUN) yegazi- ukubeka esweni isifo esinganyangekiyo sezintso (CKD) okanye ukusilela kwezintso.

Lithini inqanaba lokudala elungileyo?

Kwiimeko ezininzi, uluhlu oluqhelekileyo lwe-serum creatinine (efumaneka egazini) kumntu onezintso eziphilileyo I-0.9 ukuya kwi-1.3 mg idesilitha nganye yamadoda amadala kunye ne-0.6 ukuya kwi-1.1 mg kwidesilitha nganye yamabhinqa abantu abadala .

Nangona kunjalo, zininzi izinto eziguquguqukayo xa kufikwa kumanqanaba e-creatinine. Ngesiqhelo lixesha elithile. Ukwaphuka kwemisipha kudala i-creatinine, ke ubunzima bomzimba wakho kunye nenqanaba lomsebenzi linokuchaphazela isixa segazi lakho. Ukulinganisa ngokuchanekileyo amanqanaba egazi okudala, ugqirha uya kuqala avavanye ezi zinto zahlukeneyo ukumisela isiseko, ngokukaTaylor Graber, MD, ugqirha wobuchwephesha kunye nomseki I-ASAP IVs . Uvavanyo lwenqanaba le-Creatinine luqala ngokufumana isiseko sedemokhrasi sokuvavanya ukuba yeyiphi 'amanqanaba aqhelekileyo', uGqirha Graber uthi. Oku kuxhomekeke kubudala, ubuhlanga, isini, kunye nobungakanani bomzimba. Nje ukuba la maxabiso aqheleke, utshintsho olusuka kolu luhlu lunokubonisa ukungaqheleki kwezintso.

Ababoneleli ngezempilo bayathanda ukugcina iso kumanqanaba e-creatinine ngezizathu ezahlukeneyo. Ukuba unesifo sezintso okanye isifo sezintso, isifo seswekile, okanye esinye isifo esichaphazela izintso zakho, okanye uthatha iyeza elinokuchaphazela izintso zakho, umboneleli wakho wezempilo unokuyalela umlinganiso rhoqo we-creatinine ukubeka esweni umsebenzi wakho wezintso. Ezona ndlela zovavanyo zixhaphakileyo ligazi nomchamo.

Uvavanyo lwegazi

I-creatinine evela egazini lakho ibizwa ngokuba yi-serum creatinine, kwaye inokulinganiswa ngokuqhutywa kovavanyo lwegazi oluqhelekileyo. Xa umsebenzi wezintso usonakala, i-creatinine encinci iyakwazi ukucocwa, ekhokelela kwinqanaba eliphezulu le-creatinine egazini, uGqirha Graber uyacacisa. Ngelixa olu vavanyo lungakuxeleli ngokuthe ngqo indlela esebenza ngayo intso, inokulandelwa ekuhambeni kwexesha lotshintsho. Ababoneleli ngezempilo banokusebenzisa oku Uvavanyo lwegazi lwe-creatinine (kunye nezinto ezinje ngobudala, isini, ubuhlanga, njl.njl.) Ukubala inqanaba lokuhluza le-glomerular (GFR), elibalulekileyo ekuchongeni ukungaphumeleli kwezintso okanye isifo esinganyangekiyo sezintso.

Uvavanyo lomchamo

Enye indlela eqhelekileyo yokuvavanya amanqanaba e-creatinine kukusebenzisa Ukuqokelela umchamo iiyure ezingama-24 . Kutheni iiyure ezingama-24? Ukuzivocavoca, ukutya, kunye ne-hydration konke kunokuchaphazela i-creatinine, ke amanqanaba akho anokutshintsha yonke imihla. Ke ngoko, umboneleli wakho wezempilo uya kufuna iisampulu ezininzi zomchamo ukuya ukuvavanya imvume yakho yokudala ngokufanelekileyo . Njengoko unokucinga, olu vavanyo lubandakanya ukuqokelela yonke imchamo yakho ngaphezulu kweeyure ezingama-24, emva koko uyihambise kumboneleli wakho wezempilo. Ngokusekwe kwiziphumo, umboneleli wakho wezempilo unokumisela ukuba izintso zakho zicoca kakuhle kangakanani i-creatinine kwi-urinary tract.

Ababoneleli ngezeMpilo baya kuyalela zombini iimvavanyo ukuba zikhangeleke ngokupheleleyo ekusebenzeni kwezintso ngokuthelekisa i-GFR (eGFR) eqikelelweyo kunye nenani lomchamo we-creatinine okhoyo. Ukuba ugqirha wakho ukrokrela isifo sezintso okanye umonakalo, unokuyalela uvavanyo lwe-urea nitrogen (BUN) yegazi ukuqinisekisa isifo. Olu vavanyo lilinganisela inani le-urea nitrogen-olunye uhlobo lwenkunkuma oluhluzwe zizintso-kwisampulu yegazi.

Athetha ntoni amanqanaba okudala angaqhelekanga?

Ke, uye kwagqirha, wenza iimvavanyo, kwaye iziphumo ziku: Unamanqanaba aphezulu e-creatinine. Ngoku kuthweni? Inyathelo lokuqala-ungothuki. I-creatinine ephakanyisiweyo ayithethi ukuba izintso zakho zisezantsi. Nantoni na engaphandle kwoluhlu oluqhelekileyo (i-0.9 ukuya kwi-1.3 mg kwidesilitha nganye yamadoda amadala kunye ne-0.6 ukuya kwi-1.1 mg kwidesilitha nganye kubantu abadala ababhinqileyo) kunokubangela umboneleli wezempilo ukuba aphande ngakumbi, kodwa ayisoloko ipela ingozi.Zininzi izinto ezinokuba nefuthe kwiziphumo zakho zovavanyo. Nazi ezinye ezimbalwa:

• Ukwandisa umthambo: Ngaba ubukhe wakhatywa ngokomzimba? Ejimini yonke imihla? Le spike ekuqhekekeni kwezihlunu iya kwandisa imveliso ye-creatinine.
• Ukwanda kokusetyenziswa kweprotein: Iinyama eziphekiweyo ziqulathe i-creatinine, ke ukuba utya inyama yenkukhu kwaye uyose inyama rhoqo ebusuku, ungabona amanqanaba aphezulu.
• Ukuvalwa kwendlela yokuchama: Ukuba awukwazi ukuchama, umzimba wakho awunako ukuphelisa i-creatinine, ke amatye ezintso kunye nokunye ukuphazamiseka komchamo kuya kuyivumela ukuba ihlale kwigazi lakho.
• Amayeza athile: Ngamanye amaxesha, iziyobisi zinokuba ngunobangela. I-antibiotic trimethoprim (fumana ii-trimethoprim coupons | iinkcukacha ze-trimethoprim) kunyeCimetidine (fumana ikhuphoni zeCimetidine | iinkcukacha zeCimetidine), isilonda esiswini kunye neyeza lokutshisa, inokuthintela ukhuseleko lwe-creatinine . Ngamanye amaxesha, ii-non-steroidal anti-inflammatory drug (NSAIDs), ezinje nge-ibuprofen, nazo zinokuba ngunobangela.
• Igazi elonyukayo: Izifundo zikwabonakalisile ukuba uxinzelelo lwegazi, ukungaphumeleli kwentliziyo, kunye nezinye iimeko zentliziyo kunokubangela ukunyuka kwamanqanaba e-creatinine.

Ngokufanayo, i-creatinine ephantsi ayisoloko iyingozi. Isenokuba sisiphumo sobunzima bemisipha ephantsi (okanye isifo semisipha njenge-muscular dystrophy), ukukhulelwa, ukutya okuneprotein ephantsi, okanye iimeko ezithile zesibindi.

Ngaba amanqanaba e-creatinine anokutshintsha ngokukhawuleza?

Amanqanaba e-Creatinine anokutshintsha ngokukhawuleza, nangalo lonke usuku, yiyo loo nto ababoneleli bezempilo bebeka iliso kubo ixesha elide. Olunye uvavanyo lwegazi olubuyisa i-creatinine ephezulu egazini inokuba sisiphango. Nangona kunjalo, iimvavanyo ezininzi zilandelelana ezibonisa amanqanaba aphezulu zinokubonisa isifo esinganyangekiyo sezintso. I-spike ngequbuliso kumanqanaba e-creatinine inokuba luphawu lwesilumkiso ngomonakalo omkhulu wezintso okanye ezinye iimeko, kuxhomekeke kwiimpawu.

Luphi unxibelelwano phakathi komhlaza kunye namanqanaba e-creatinine?

Amanqanaba okudala angaqhelekanga angabonisa nezintso okanye umhlaza wedlala lobudoda. Nangona, i-creatinine ephezulu okanye ephantsi iyodwa ayithethi ukuba unomhlaza.

Indlela yokunciphisa amanqanaba e-creatinine

Umboneleli wakho wokhathalelo lwempilo uwaphatha njani amanqanaba akho angaqhelekanga e-creatinine axhomekeke ngokupheleleyo kwisizathu esisisiseko. Utshintsho kwindlela yokuphila kunye nokutya kunokuba lunyango olulula nolusebenzayo lwamatyala amancinci. Kodwa isifo esinganyangekiyo sezintso, ukonakala kwezintso, okanye ukusilela kwezintso kufuna iinkqubo ezomeleleyo. Amayeza okulawula iimpawu, i-dialysis, okanye iimeko ezibi kakhulu, ukufakelwa kwezintso kunokuba yimfuneko. Nazi iindlela ezimbalwa ezinokubakho zokunciphisa amanqanaba e-creatinine:

Kwenziwe ntoni

• Hlala hydrated
• Ukunciphisa ukutya kweprotein
• Ukunciphisa umsebenzi onamandla (kodwa ungayinqumli umthambo ngokupheleleyo!)
• Fumana ifayibha ngakumbi ekutyeni (ngakumbi iziqhamo kunye nemifuno)

Yintoni ekufuneka uyiphephe

• Yenza izongezo okanye enye izongezo zomzimba
• Ukutya okune-sodium ephezulu
• Ukutshaya
• Ukusela kakhulu utywala

Unyango lwendalo

• Izongezo zeChitosan ibonakalise ifuthe elihle kwimpilo yezintso
• USalvia lunyango lwesiTshayina yesifo sezintso
• Iti eluhlaza okanye iti ye-herbal-ngokukodwa i-nettle, i-chamomile, i-ginseng, kunye nengcambu yedandelion
• Isinamon

Amayeza

Akukho machiza anciphisa ngokuthe ngqo inani le-creatinine egazini lakho. Ukuba ugqirha ufumanisa isifo sezintso esibangela amanqanaba okudala angaqhelekanga, unokuyalela amayeza ukunciphisa iimpawu. Amachiza amiselweyo abandakanya:

• I-Angiotensin-eguqula i-enzyme (ACE) inhibitors njenge ILotensin (benazepril) kunye neCapoten ( captopril ) ukuya uxinzelelo lwegazi oluphezulu .
• I-Angiotensin II Receptor Blockers (ARBs) njengeEdarbi(azilsartan) kunye neTeveten (eprosartan) inyanga uxinzelelo lwegazi oluphezulu kwaye inokunciphisa inani leeprotheyini kumchamo wakho.
• Iiarhente ze-Erythropoiesis-ezikhuthazayo (ii-ESA) ukunceda ukwandisa inani elibomvu leeseli zegazi.
• I-Phosphate okanye i-potassium binders ukunceda ekupheliseni i-phosphate eyongezelelweyo kunye ne-potassium ezingenakucoca izintso zakho.

Ezinxulumene : Iinkcukacha zeLotensin | Iinkcukacha zeCaptopril

Zama ikhadi lesaphulelo esisodwa

Ekugqibeleni, elona cebiso lilungileyo lokwenza umsebenzi wezintso kukuphila ngendlela esempilweni. UGqirha uGraber uthi: Ukunciphisa ukutya okungenampilo okuphezulu kwizithako ezenziweyo, ukwanda kweziqhamo kunye nokutya kwemifuno, ukuzilolonga rhoqo (imizuzu eli-150 yomlinganiselo olinganiselayo okanye imizuzu engama-75 yomthambo owomeleleyo we-aerobic ngeveki), ukuhlala uhlanjululwe, kunye nokugcina ubunzima bomzimba Uluhlu olusempilweni (ubunzima bomzimba obungama-20 ukuya kuma-25) zizinto ekufanele zijolise ekuhambeni kwexesha ukuqinisekisa ukuba unika umzimba izixhobo ezifunekayo ukuze uphumelele.