Ukwabelana ngesondo kwii-anti-depressants: Ukuphonononga iziphumo zesondo ze-SSRI
IindabaKwisithuba seminyaka eli-15, inani labantu baseMelika abathatha i-anti-depressants lonyuke phantse ngama-65%, lisuka ukusuka ngaphantsi kwe-8% yabemi base-US ukuya phantse i-13% . Uphando lubonisa abantu abaqala ukuthatha i-anti-depressants ukunceda ukulawula impilo yabo yengqondo ngamanye amaxesha bafumana abakwazi ukuyeka -Ngaphandle kweziphumo ebezingalindelekanga ezinokubakho.
Ukukhetha i-serotonin reuptake inhibitors ( SSRIs ) ziphakathi kwezona zixhaphakileyo zichazwe kwi-anti-depressants, kwaye ngelixa zingathathelwa ngqalelo njengemilutha, iziphumo ebezingalindelekanga ze-SSRI zinokubandakanya ukozela, isicaphucaphu, ukuqaqanjelwa sisisu, ukungazinzi, kunye nokungasebenzi kakuhle ngokwesondo.
Ukujonga kufutshane nefuthe lokuthomalalisa uxinzelelo njengama-SSRI kubantu baseMelika nakumaxesha abo obona buhlobo, sivavanye abantu abayi-1 000 abasandula ukuphathwa nge-SSRI okanye nge-non-SSRI antidepressants. Funda njengoko sijonga ukuba bangaphi abasebenzisi abazi ngeziphumo ebezingalindelekanga zesini kunye nee-SSRIs kwaye bangaphi abakholelwa ukuba ezi ziphumo bezingalindelekanga kufanelekile.
Amayeza oxinzelelo-kunye neempembelelo zalo
Uxinzelelo kuluhlu njengoyena nobangela uphambili wokukhubazeka kwihlabathi liphela kubantu abaneminyaka eyi-15-44, ngokwe-Anxiety and Depression Association of America. Phakathi kwezifo zengqondo eziqhelekileyo kulo lonke elaseMelika, malunga I-7% yabantu abadala uxinezeleko. Iimpawu zinokubandakanya iimvakalelo zokudakumba, ukulala, ukudinwa, amajoni omzimba abuthathaka, kunye a umngcipheko ophezulu wokuhlaselwa sisifo sentliziyo .
I-serotonin reuptake inhibitors ekhethiweyo (i-SSRIs) zezona zinto zichaziweyo eMelika. Ngokwandisa amanqanaba e-serotonin kwingqondo, ii-SSRI ngamanye amaxesha zimiselwe ukunceda ukunyanga ezinye iimeko, kubandakanya ukuphazamiseka koxinzelelo . Ii-SSRI azikho ngaphandle kwemiphumo emibi, nangona kunjalo. Ixhomekeke ku Iipesenti ezingama-73 zabantu abathatha ii-SSRI Amava ohlobo oluthile lwempembelelo yesondo kolu didi lweziyobisi. Ngelixa iziphumo ebezingalindelekanga zinokwehla emva kweeveki ezimbalwa kwii-SSRI, ezinye izigulana zinokunganyamezeli kunyango.
Ukuqaqanjiswa kwempembelelo yesini kunye nee-SSRIs
Abaphandi bayaqonda ukuba ii-SSRI zibonakala ngathi zinegalelo kukungasebenzi kakuhle ngokwesondo, kodwa bayavuma ukuba ukulinganisa impembelelo yokwenyani ye-anti-depressants ukuqhuba ngesondo kunye nokusebenza kunokuba nzima. Ngamanye amaxesha, ukungaziphathi kakuhle ngokwesondo kunokubakho ngaphambi kokungeniswa kwe-SSRI njengonyango (ukungasebenzi kakuhle ngokwesondo ikwaluphawu loxinzelelo), okanye kunokunxulumana nolunye uhlobo lomzimba. Kwezinye izigulana, onke amanqanaba okusondelelana, ukusukela kumnqweno wokuya kwisini kunye ne-orgasm, anokuthintelwa ngokusetyenziswa kwe-SSRI.
Sifumene ngaphezulu kwe-82% yabantu abanembali yokuthatha i-anti-depressants babeyazi imiphumo emibi yesondo. Okwangoku, uninzi lwalusebumnyameni malunga nokuba amayeza abo abachaphazele njani ukuqhuba kwabo ngokwesondo kunye nokusebenza. Ngaphezulu kwe-12% yabantu abafumana iziphumo ebezingalindelekanga kwizidambisi ezingakhange bazazi ukuba unyango lwabo lunokubangela ukungasebenzi kakuhle, kulandele phantse iipesenti ezingama-47 zabantu abangenakho ukuxela ekuziphatheni ngokwesondo.
Ukubaluleka konxibelelwano nesigulana
Unxibelelwano phakathi koogqirha, abaguli, kunye nabasebenzi baseofisini yinxalenye yokhathalelo lwempilo. Iimpazamo zonxibelelwano, ezinokuba yingozi ukuba azibulali, zivela kukungabikho kokuqonda, iincoko ezingabhalwanga, okanye iingxoxo eziphosiweyo ngokupheleleyo. Kwiimeko ezininzi, unxibelelwano oluphosakeleyo okanye unxibelelwano oluphosiweyo lubangela iimpazamo ze ubukhali obuphakathi okanye obuphezulu .
Phantse i-50% yabasetyhini kunye nangaphezulu kwe-28% yamadoda ibonise ukuba oogqirha babo abakhange bachaze konke okuthe gca ngokwesondo kwii-SSRI.
Ngelixa abasetyhini babenethuba elininzi kunamadoda lokungafumani nkcazo koogqirha malunga nokuziphatha gwenxa ngokwesondo, abasetyhini nabo babengenamathuba okuba baphakamise iingxaki ezifanayo koogqirha babo (26%) okanye inkxalabo yabo ithathelwe ingqalelo ngoogqirha babo (63%) . Abantu abanembali yokusebenzisa i-anti-depressant bahlala behlazekile okanye bengakhululeki ukuthetha ngeziphumo ebezingalindelekanga zesini ze-SSRI nogqirha, kulandele abantu abaziva ukuba izibonelelo zingaphezulu kwempembelelo embi kubomi babo bobulili.
Umngcipheko kunye nomvuzo: Iziphumo ebezesondo ze-SSRI
Amashumi asixhenxe anesithathu eepesenti yabasetyhini kwaye phantse ama-63% yamadoda avumile ukuziva benqwenela ukunciphisa isondo ngelixa bethatha ii-SSRI, kwaye phantse i-41% yabasetyhini kunye ne-35% yamadoda bathi baphulukene nomnqweno wesini ngokupheleleyo. Ngelixa ukutshintsha kweminqweno yesini okanye ukusondelelana kuyinto eqhelekileyo, iingcali zilumkisa ukuba xa loo mnqweno uphela ngokupheleleyo, unokuba nefuthe elibi kuzo zombini ubudlelwane kunye nomgangatho wobomi. Ngokukodwa kwabasetyhini, abaphandi bacetyisa ukuba akuqhelekanga I-libido ephantsi kunye noxinzelelo lokudibana .
Abasetyhini kwii-SSRI babenethuba lokuxela amandla anciphisiweyo e-orgasm, ukungakwazi ukwenza i-orgasm, ukungakwazi ukuvuswa, kunye nentlungu ngexesha lokwabelana ngesondo. Sekunjalo, okukhona kusebenza ngakumbi ukuba izigulane ze-SSRI zifumene unyango, bebexhalabile kakhulu ngenxa yeempembelelo zeziyobisi. Xa kuthelekiswa nabantu abangama-32% abakholelwa ukuba ii-SSRI zazingasebenzi kakuhle, iipesenti ezingama-79 zezigulana ezafumanisa ukuba ii-SSRI zisebenza kakhulu zazizimisele ukwamkela iziphumo ebezingalindelekanga.
Impembelelo ye-antidepressants kubudlelwane bezothando
Ii-SSRI zisenokuba zezona zinto zichaziweyo ezichasayo, kodwa ayisiyiyo kuphela indlela yonyango ekhoyo. I-Serotonin kunye ne-norepinephrine reuptake inhibitors (SNRIs), uhlobo olutsha lwe amayeza antidepressant , kunye ne-norepinephrine kunye ne-dopamine reuptake inhibitors (i-NDRIs) ikwabonisa ukhetho olunokubakho kunyango. Ezinye i-anti-depressants ezingachaphazeli i-libido njengoko ezinye ii-SSRI zibandakanya: Wellbutrin ( bupropion ) kunye trazodone .
Abantu abanembali yokusebenzisa i-anti-depressant babesenokwenzeka ukuba banike ingxelo yokuba neentlobano zesini ezibi ngakumbi kunaleyo ingeyiyo-SSRIs. Phantse i-60% yabasetyhini kunye ne-54% yamadoda kwii-SSRI zathi ziyabenzakalisa ubomi babo bezesondo, zilandelwa ngama-30% abasetyhini kunye ne-26% yamadoda kwii-SSRI ezinolwalamano olunokuthi lukhule ngokwahlukana ngenxa yeyeza labo lokudakumba.
Iindlela zokunciphisa iimpawu ze-SSRI
Amanqaku ophando kulungelelwaniso oluphezulu phakathi kwe-anti-depressants kunye nokungasebenzi ngokwesondo, kodwa ezinye izisombululo zivumela impembelelo entle ngakumbi yoxinzelelo. Iidosi eziphezulu zihlala zikhokelela kwisiphumo se- umngcipheko ophezulu weziphumo ebezesondo , ke ukuthetha nogqirha malunga nokunciphisa idosi kunokunceda. Ukuthatha i-anti-depressants ngexesha elithile losuku kunokunceda ukunciphisa uxinzelelo kwimisebenzi yesondo.
Okwangoku, abantu abaninzi bakhethe ukungenzi nto malunga nefuthe le-SSRI kubomi babo bobulili. Iipesenti ezingama-50 zabasetyhini kunye ne-42% yamadoda khange bazame ukoyisa iziphumo ebezingalindelekanga zesini kwabo bachasene noxinzelelo, kwaye kuphela yi-14% yabasetyhini kunye ne-19% yamadoda axele ukuba athetha nogqirha.
Abanye abantu batshintshe amayeza ngokupheleleyo, ngelixa abanye baguqula idosi yabo, bazisa iithoyi zesini kwigumbi lokulala, okanye imisebenzi yesondo ehleliweyo.
Ukubaluleka konxibelelwano phakathi kwamaqabane athandanayo
Unokuziva ngathi kufuneka ukhethe phakathi kokuqhubeka nokuthomalalisa uxinzelelo okanye ubomi obungcono besini. Nangona kunjalo, kunokwenzeka ukuba ufumane ibhalansi phakathi kokunyanga uxinzelelo (okanye uxinzelelo) ngaphandle kweziphumo ebezingalunganga.
Iingcali zincoma ukwanda unxibelelwano phakathi kwamaqabane athandanayo ukunqanda uxinzelelo kunye noxinzelelo olungeyomfuneko. Ukuhlengahlengisa ebomini kwi-anti-depressants kunokuba nzima, kwaye wonke umntu usabela kubo ngokwahlukileyo. Ukwenza incoko evulekileyo phakathi kwezibini kunokunceda ekupheliseni ukwenzakala ngokweemvakalelo.
Amashumi asibhozo anesine eepesenti zabantu abatshatileyo bathethe ngeziphumo ebezingalunganga ezibangelwa zizidambisi, zilandelwa ngabantu abangama-81% kubudlelwane. Ngelixa ama-68% abantu abaqhawule umtshato ngoku okanye abohlukanisiweyo nabo bavulelekileyo kumaqabane abo ngelo xesha, kuphela ngama-66% abantu abangatshatanga ababelana ngamava abo kwii-SSRI. Kulabo babekhululekile ukuvula malunga nokudakumba kwabo ngokwesondo, ngaphezulu kwe-22% baxele ukukhula besondela kumaqabane abo, xa kuthelekiswa ne-10% kuphela abangazange bathethe neqabane labo.
Iimbono kwimpilo yengqondo
Abantu ababenamava obomi kubomi be-anti-depressants kunye nee-SSRI basinika izimvo zabo malunga nendlela yokujongana neziphumo ebezingalunganga zesondo.
Njengoko ubona kwiimpendulo zabo, ukuthetha ngale meko kunye nokuchaza iimvakalelo zakho bekuhlala kuyinto ekhuthazwayo. Ngelixa kunokuziva kunzima okanye ungonwabanga ekuqaleni, ukuvula ngamava akho ezesondo njengoko omnye wenu eqala unyango kunokunceda ukunqanda ukudideka, ukucinga, kunye nokuziva ubuhlungu.
Ukongeza, abantu abaninzi bayakuqonda ukubaluleka kokwabelana ngala mava nogqirha xa befumana iziphumo ezibi zesondo.
Isiphelo
Ngaphezulu kwezigidi ezili-16 zaseMelika zinexinzelelo, kwaye uninzi lwazo luyayinyanga le meko nge-anti-depressants kubandakanya ne-SSRI. Ngelixa la mayeza anokubonelela ngoncedo olufunekayo, uninzi lwabantu luxela ukungabinakho ukusebenza ngokwesondo kunye nokunciphisa umnqweno wesondo ngenxa yonyango. Ngokusekwe kuphando lwethu, kubonakala ngathi kukho umsantsa kunxibelelwano phakathi koogqirha kunye nezigulana malunga nohlobo lwezi ziphumo zesondo, ngakumbi phakathi kwabafazi.
Naliphi na iyeza olisebenzisayo, indleko akufuneki ibe sisiphumo secala esongeziweyo. Nge Ukhathalelo , Injongo yethu kukwenza ukonga kumayeza akho amayeza ngokulula kangangoko kunokwenzeka. Sebenzisa iwebhusayithi yethu okanye usetyenziso ukufumana amayeza akho, thelekisa amaxabiso, kwaye ugcine kwikhemesti oyithandayo.
Indlela yokusebenza
Ngokusebenzisa iMechanical Turk yaseAmazon, siqokelele iimpendulo ezivela kubathathi-nxaxheba abali-1,002 ababesandula kunyangwa nge-SSRI antidepressants okanye ii-non-SSRI. I-60.3% yabathathi-nxaxheba bethu yayingabafazi, kwaye i-39.7% yayingamadoda. Abathathi-nxaxheba babeneminyaka yobudala ukusuka kwi-18 ukuya kwi-71 ngentsingiselo ye-35.7 kunye nokuphambuka komgangatho kwe-10.4. Abaphenduli abangafumaniswanga ukuba banokudakumba okanye abangazange babe neemvakalelo zokudakumba bakhutshelwa ngaphandle kuvavanyo, ukongeza kwabo babengakhange banyangwe nge-anti-depressants.
Idatha esiyibonisayo ixhomekeke kukuzixela. Idatha yokuzixela inemicimbi efana nokukhetha inkumbulo, iteleskopu, ukubonwa kunye nokubaxa. Imizekelo yeedatha ezinokuthi zichaphazeleke kolu phononongo yingxelo esecaleni yeempembelelo zoxinzelelo kuhlobo lwamandla, kunye namava okuba neziphumo ebezingalindelekanga. Akukho kuvavanywa kweenkcukacha-manani kwenziwa kule datha, ke amabango adweliswe apha ngasentla asekwe kwiindlela zodwa.
