Unyango olusebenzayo lwe-PCOS 5

Imfundo yezeMpilo

I-Polycystic ovary syndrome, ebizwa ngokuba yi-PCOS, sisifo esintsonkothileyo sehomoni esichaphazela malunga ne-6-12% yabasetyhini eUnited States ngexesha lokuzala. Ikwayesinye sezizathu eziqhelekileyo zokuba ungachumi, ngokuka Amaziko oLawulo noThintelo lwezifo (CDC), kodwa kungenxa yokuba ubukhulu becala ayaziwa. Oko kwenza ukuba kube nzima ukuphawula eyona PCOS yonyango.

Zithini iimpawu zePCOS?

Ngenxa yokungalingani kwamanqanaba ehomoni kwii-ovari, izikhombisi eziqhelekileyo ze-PCOS zibandakanya amaxesha aphosiweyo okanye angaqhelekanga, amaxesha anzima kakhulu okuya exesheni, kunye / okanye ukungakwazi ukukhupha amaqanda (okanye ukuvota). Ukuphazamiseka kokuya esikhathini kunokukhokelela kwezinye iimpawu kunye nemiphumo emibi, njengama-cysts kuma-ovari. Kwakhona, ukuba owasetyhini one-PCOS unentabalala yehomoni yindoda kunye ne-androgen, umzimba wakhe uya kuphendula ngokukhula komzimba kunye nobuso ebusweni, kunye nokukhula kwamabala amabi kunye nebala lendoda. Ukutyeba kwakhona luphawu lwePCOS.

I-PCOS ayibeki mngciphekweni wobomi, kodwa inokwenza ubomi bube buhlungu, utsho I-Shweta Patel, MD , i-OB / GYN e-Orlando yezeMpilo eGqirha e-Orlando, eFlorida. Ingakhokelela kwiimpawu ezingathandekiyo kwaye ezibonakalayo ezibonakalayo kwaye wenze iwindow yakho ye-ovulatory ijolise ekujoliseni, ngaloo ndlela yenza kube nzima-kodwa kungenakwenzeka-ukukhulelwa ngexesha elifanelekileyo.

Yintoni ebangela iPCOS?

Uninzi lwabafazi abazizigidi ezi-5 banesifo se-polycystic ovarian syndrome, kodwa isizathu asaziwa. Izinto ezimbalwa zomngcipheko oqhelekileyo zibandakanya:

• yemfuza
• ukutyeba kakhulu
• amanqanaba aphezulu e-insulin (iproteni enceda ukulawula amanqanaba eswekile yegazi)
• amanqanaba aphezulu e-androgen

Uphononongo lwe-2018 olupapashwe kwi-Intanethi kwi Ijenali yaMazwe ngaMazwe yoPhando lwezeNdalo kunye neMpilo yoLuntu Ndigqibe kwelokuba ubuhlanga okanye indawo ekuyo ayidlali ndawo kwi-PCOS.

Ngaba zikhona ezinye iimeko ezinxulunyaniswa nePCOS?

Nangona kunjalo, uphando lubonisa ukuba iimeko ezininzi zempilo zinxulunyaniswa nesi sifo-nangona sisekufuneka simiselwe ukuba ngaba i-PCOS ibangela le micimbi okanye kungenjalo. Inkqubo ye- IOfisi yezeMpilo yabaseTyhini (Eqhutywa liSebe lezeMpilo laseMelika kunye neNkonzo zaBantu) uluhlu lweengxaki zempilo zexesha elide ezinxulumene nePCOS:

• Seswekile: Ngaphezulu kwama-50% abasetyhini abafunyaniswe ukuba bane-PCOS bakhula nesifo seswekile okanye isifo seswekile ngaphambi kweminyaka engama-40, utshilo i-CDC .
• Uxinzelelo lwegazi: Abasetyhini abane-PCOS basemngciphekweni wezempilo wokuba noxinzelelo lwegazi, olukhokelela kwisifo sentliziyo.
• IHypercholesterolemia: Abasetyhini abane-PCOS kunokwenzeka ukuba babe namanqanaba aphezulu e-LDL (embi) i-cholesterol xa kuthelekiswa nabasetyhini ngaphandle kwe-PCOS.
• I-apnea yokulala: Abasetyhini abane-PCOS basemngciphekweni omkhulu wokukhula kwesi sifo sokuphefumla, apho ukuphefumla okomzuzwana kuyekisa ukulala. Le meko inokukhokelela kwisifo sentliziyo kunye neswekile.
• Uxinzelelo kunye noxinzelelo: Uphononongo olucwangcisiweyo luka-2016 kunye nohlalutyo lweemeta olupapashwe kwiphephancwadi Isifo seNeuropsychiatric kunye nonyango ifumanise ukuba abasetyhini abane-PCOS baphantse babe mathathu amathuba okuba babe noxinzelelo xa kuthelekiswa nabasetyhini abangenayo i-PCOS. Iziphumo zazifana nezo zafunyaniswa zine-PCOS kunye neempawu zokudakumba.
• Umhlaza we-Endometrial: Uphononongo lweqela labemi base2018 elipapashwe kwiphephancwadi Iyeza waqukumbela ukuba abasetyhini abane-PCOS babenomngcipheko obalulekileyo ophucukileyo wokuba nomhlaza wesibeleko.

Ngaba iyanyangeka iPCOS?

I-PCOS ithambekele ekubeni sisifo esilawulwa endaweni yokunyanga kuba ihlala iphinda ibuye, ngakumbi ukuba isigulana sizuza (okanye siphinda sibuye) ubunzima bomzimba kunye / okanye sifunyenwe sinesifo seswekile, siyachaza UJessica Shepherd, MD , i-OB / GYN ene-Gynecology encinci yohlaselo kwiziko lezonyango i-Baylor University eDallas, eTexas. Kuba iimpawu zahlukile, uGqr. Patel wongeza ukuba uyathanda ukulungelelanisa unyango kwiinjongo zesigulana.

Iphathwa njani iPCOS?

Unyange i-PCOS ngokudibanisa ezi ndlela zokuphila zilandelayo kunye namayeza. Nazi iindlela ezintlanu zonyango lwe-PCOS onokuthi uziqwalasele.

1. Ukutya

Ugqirha Shepherd uthi ukutshintsha indlela otya ngayo (mhlawumbi kwisicwangciso esinamafutha asezantsi) kuya kunceda ukulahla iiponti ezingafunekiyo. Ngamanye amaxesha, ukunciphisa umzimba kunokuphucula uvakalelo lwe-insulin, ukuya exesheni, kunye nokunyusa ukuzala. Kwakhona, ukuguqulwa kokutya kunokunceda ukumelana ne-insulin kunye nokunciphisa amathuba okuba ngumcimbi we-metabolic, onokubangela isifo seswekile, i-hypercholesterolemia, okanye uxinzelelo lwegazi, uyaqhubeka.

2. Ukulawulwa kokuzalwa

Kwabafazi abangajonganga ukukhulelwa, izinto zokucwangcisa ngomlomo zinokunceda ekulawuleni amaxesha kwaye zinike ne-cyclic estrogen, ehlala iphazamiseka, utshilo uGqirha Shepherd. I-gynecologist inokuyalela ngokudibanisa iipilisi zokulawula ukuzalwa okanye ezinye iindlela zokuthintela ukukhulelwa eziqulathe zombini i-estrogen kunye neprogestin (enjenge-vaginal ring ring) ukunciphisa ukopha okungaqhelekanga, ukunciphisa ukukhula okungaphezulu kweenwele, ukunciphisa amabala, kunye nokunciphisa umngcipheko womhlaza we-endometrium.

3. IMetformin

I-Metformin [iyeza elichasene nesifo seswekile] ibonakalise ukubuyisela ukuqala kwakhona, kwimijikelezo yokuya esikhathini kwi-40-90% yezigulana ezifundisiweyo, utshilo uGqirha Shepherd. Wongeza ukuba amayeza amiselweyo anokuphucula ukuchumisa kunye nenqanaba lokukhulelwa kwabasetyhini abane-PCOS,nangona ukusetyenziswa kwesi sikhokelo kuthathwa njenge-off-label kwaye kufuneka kuxoxwe nodokotela wakho. Imilomo yomlomo yodidi lweziyobisi ekuthiwa ziiguanides, metformin yenzelwe ukwandisa impendulo yomzimba kwi-insulin ukuze ilungelelanise amanqanaba eglucose kubantu abafunyenwe benesifo seswekile sesi-2. Uphononongo luka-2015 olupapashwe kwiphephancwadi Unonophelo lweSwekile ifumanise ukuba eli yeza linokunciphisa amanqanaba e-cholesterol ye-LDL. Iswekile yeglucophage Igama elidumileyo lophawu lwe-metformin.

Ezinxulumene: I-Metformin yonyango lwangaphandle kwelebula ye-PCOS

4. Amayeza e-anti-androgen

Uhlobo lonyango olusetyenziselwa ukubhloka i-androgens (aka zesini iihomoni zesini kubandakanya i-testosterone), la machiza anokunceda ukunciphisa naziphi na iimpawu zobudoda ezinxulumene ne-PCOS, ezinje ngamabala, iinwele ezingafunekiyo, kunye noboya bezinwele obuhlelayo. Ukunyanga i-androgens egqithileyo kunokufezekiswa ngokusebenzisa i-spironolactone [i-diuretic emiselweyo ukunyanga uxinzelelo lwegazi oluneziphumo ezichasene ne-androgenic], nokuba kukodwa okanye kudityaniswe nepilisi yolawulo lokuzalwa, uGqirha Patel uthi. Kwaye uGqr. Shepherd wongeza ukuba ukunciphisa isenzo se-testosterone kunokunciphisa i-hirsutism [ukukhula kwendoda kwipateni yokukhula kwabasetyhini] ngamanqaku ngama-40%. IOfisi yezeMpilo yabaseTyhini ilumkisa ukuba olu didi lwee meds lunokubangela iingxaki ngexesha lokukhulelwa. Unokuphinda ubuze ugqirha wakho we-endocrinologist malunga neVaniqa, esisiciko sokususa iinwele.

5. Imodyuli ye-Estrogen

Ukuze anyange ukungachumi, uGqirha Patel uthi oogqirha badla ngokuyalela umntu ukuba asebenzise i-estrogen, njenge-clomiphene citrate — iyeza lomlomo elaziwa njengeClomid, elikwicandelo leziyobisi ekuthiwa zii-ovulatory stimulants. Isebenza ngokufana ne-estrogen ngokukhuthaza ii-ovari ukuba ziphuhlise kwaye zikhulule amaqanda. Inqaku lika-2015 elipapashwe kwiphephancwadi Iiklinikhi uxele ukuba abasetyhini abane-PCOS abasebenzisa i-clomiphene citrate njengonyango lokuqala lonyango lokungachumi banenqanaba lokukhulelwa lama-70%.