I-FDA yamkela iQelbree, iyeza elitsha le-ADHD elingavuseleliyo
Iindaba Olu lukhetho lokuqala olutsha olunganyanzelisiyo oluvunyiweyo lwabantwana kwiminyaka eli-10Ulawulo lwezoKutya kunye noLawulo lweeDrug (i-FDA) lwamkele iQelbree, iyeza lokuqala elinganyanzelisiyo le- Unyango lokunqongophala kwengqondo kukuphazamiseka kwengqondo (ADHD) ebantwaneni nakwishumi elivisayo ngaphezulu kweminyaka eli-10.
Yenziwe nguSupernus Pharmaceuticals, Inc., iQelbree (i-viloxazine capsule-release-release capsules) yinto ekhethiweyo ye-norepinephrine reuptake inhibitor-udidi lweziyobisi ezisetyenziselwa ukunyanga unxunguphalo noxinzelelo, ngamanye amaxesha i-ADHD. I-Qelbree yamkelwe ukunyanga abantu abancinci abane-ADHD phakathi kweminyaka eyi-6 kunye ne-17 yeminyaka.
I-Qelbree: Unyango olutsha olungakhuthazi unyango lwe-ADHD
Malunga ne-70% yabantwana abane-ADHD bathatha uhlobo oluthile lonyango kuyo, ngokweZiko leSizwe lezeMpilo yeNgqondo (NIMH).
Uninzi lwazo lumiselwe amayeza avuselelayo, asebenza ukwandisa amanqanaba e-dopamine kwingqondo ukubanceda bajonge ingqalelo yabo ngcono. Nangona kunjalo, abanye abazali bakhetha ukunqanda izinto ezikhuthazayo ebantwaneni babo ngenxa yenkxalabo yeziphumo ebezingalindelekanga ezinje ngokungahlaliseki, iingxaki zokulala, ukungabinamdla wokutya, kunye nabanye. Okanye, abanye abantwana abanako ukuthatha izikhuthazi ngenxa yenye imeko yezempilo.
Ukuvunywa kweQelbree kuthetha ukuba kungekudala abazali baya kuba nenye indlela yokunyanga abantwana babo abane-ADHD.
Okwangoku, zikhona amanye amayeza e-ADHD amathathu angavuseleliyo ekwanayo imvume ye-FDA: IStrattera ( atomoxetini ), I-Intuniv kunye neTenex ( guanfacine ), Kunye neKapvay ( clonidine ER ).
Ndicinga ukuba kubaluleke kakhulu ukuba nolunye ukhetho olungavuseleliyo, utsho UAndrew Cutler, MD , Unjingalwazi wezonyango kwi-SUNY Upstate Medical University kunye nomphandi wolingo lwezonyango ofunde ukusetyenziswa kweQelbree. Leyo yeyona mfuno inkulu engafezekiswanga kunyango lwe-ADHD.
Ndonwabile malunga namandla alo, utsho ugqirha wezifo zengqondo USasha Hamdani , MD, ingcali yeklinikhi ye-ADHD eKansas City. Ndiyayithanda inyani yokuba ayikhuthazi, yiyo ke loo nto kuncitshiswa ukusetyenziswa gwenxa kunye nokwenza ukuba kungabikho nzima ukuyifumana.
Izibonelelo zeQelbree
Ngokukhetha unyango olutsha lwe-ADHD, yiza nezibonelelo ezitsha kubantwana abane-ADHD.
1. Ifom entsha yonyango
Ngokungafaniyo nezinye iziyobisi ze-ADHD ezingezizo ezikhuthazayo, iQelbree iyafumaneka kwifomule, utshilo uGqirha Cutler. (I-Strattera kunye ne-generic, i-atomoxetine, ziza kwifom ye-capsule, kodwa kufuneka ithathwe yonke.) Oko kuthetha ukuba abazali banokuvula ii-capsules kwaye bafafaze iziqulatho ze-capsule ye-Qelbree kwi-teaspoon ye-applesauce. Kukho ezinye izigulana ezingakwaziyo ukuginya ipilisi- okanye ngekhe, utshilo uGqirha Cutler. Oku kunika enye indlela yokufumana iyeza kubo.
2. Ukuqala ngokukhawuleza
Olunye uncedo, ngokukaGqirha Cutler, kukuqala ngokukhawuleza kokusebenza. Oko kukuthi, amayeza awathathi xesha lide ukuqala ukusebenza kwaye ancede umntwana oyifunayo.
3. Ukwenziwa kokukhutshwa okundisiweyo
Ulawulo olwenziwa kanye ngemini yibhonasi, utshilo uGqirha Hamdani. Iyanciphisa isidingo sokufumanisa i-dosing imini yonke, enokuthi ibe nzima kwaye ingabi nakwenzeka, ngakumbi ukuba abazali bane-ADHD, nabo.
Ukungancedi kweQelbree
Kukho imida ethile kunyango olutsha.
1. Isilumkiso ngamayeza
Njengakwi-atomoxetine, ilebheli yeQelbree inesilumkiso malunga neengcinga zokuzibulala kunye nokuziphatha kwizigulana zabantwana. Izigulana zalo naliphi na ixesha elinyangiweyo ngala mayeza kufuneka zijongwe ngononophelo.
Ukusetyenziswa okulinganiselweyo
Okwangoku, imvume yeQelbree yenzelwe ukusetyenziswa kuphela ebantwaneni nakwishumi elivisayo. Kodwa uphando luyaqhubeka ukuphanda ukubanakho Abantu abadala abane-ADHD , kananjalo. Njengoko uGqirha Cutler esitsho, i-ADHD yimeko yobomi bonke echaphazela abantu abadala, uninzi lwabo luthatha amayeza. Ngokwe-NIMH, ukuxhaphaka kwe-ADHD kubantu abadala eUnited States kunjalo malunga ne-4.4% , izehlo eziphakamileyo kancinane emadodeni kunabafazi.
Izicwangciso zikaSupernus zokwenza ukuba iQelbree ifumaneke kwizigulana ekupheleni kwekota yesibini ye-2021, okuthetha ukuba inokuba ilungile ngexesha lokuqala unyaka omtsha wesikolo .
