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Umthamo weGabapentin, iifom, kunye namandla

Ulwazi lweziyobisi

I-Gabapentin sisiyobisi esenziwa ngu-generic esivunyiweyo yi-FDA njengonyango olongezelelekileyo kunye namanye amayeza okuxhuzulwa ngokuyinxalenye kwabo banesathuthwane. Ingasetyenziselwa ukunyanga iintlungu zentliziyo kwi-neuralgia yasemva kwexesha (ingxaki ye amatyathanga ). I-Gabapentin ihlala imiselwe ngaphandle kwelebheli kwezinye iimeko ezininzi, ezinje ngesifo seswekile, ifibromyalgia , kunye nokuxhomekeka kotywala.

I-Gabapentin imiselwe njenge-generic, kodwa ichiza likwafumaneka phantsi kwamagama egama Neurontin kwaye Ukuhlambalaza . Ezinye izigulana zinokumiselwa iziyobisi ezifanayo ne-gabapentin-enje nge-Horizant (gabapentin enacarbil) okanye i-Lyrica (pregabalin) -kwaye i-gabapentin.

IGabapentin ithathwa njengecwecwe, njengephilisi, okanye ulwelo lomlomo. Umthamo uya kuxhomekeka kwimeko yokuphathwa, ubudala bomntu onyangwayo, kunye nokusebenza kwezintso. Umthamo oqhelekileyo wokuxhuzula uqala kwi-300 mg ngosuku lokuqala. Idosi inokunyuswa de kufikelelwe idosi esebenzayo, edla ngokuba yi-300 ukuya kwi-600mg ethathwe kathathu ngemini.

Ezinxulumene: Yintoni i-gabapentin? | Amatikiti eGabapentin

Iifom yedosi yeGabapentin kunye namandla

IGabapentin ithathwa ngomlomo njengepilisi, i-capsule, okanye isisombululo somlomo.

Amacwecwe: I-600 okanye i-800 mg kwithebhulethi nganye
Iicapsules: 100, 300, okanye 400 mg ngephilisi nganye
Ulwelo: I-250 mg nge-5 milliliters (ml) yolwelo lomlomo

Umthamo weGabapentin wabantu abadala

Kubantu abadala, i Umthamo we-gabapentin zinokwahluka ngokubanzi kuxhomekeke kwimeko yokunyangwa. Xa uqala unyango nge-gabapentin, idosi yokuqala inokuba yi-100 ukuya kuma-300 mg ngosuku kwaye inyuke ngokuthe chu de kufikelelwe kwidayisi efanelekileyo. Elona dosi liphezulu liya kuxhomekeka kwimeko yokuphathwa.

Umgangatho osemgangathweni we-gabapentin kubantu abadala: I-300-600 mg ithathwa kathathu ngemini.
Ubuninzi be-gabapentin dosage yabantu abadala: I-1200 mg ithathwe kathathu ngemini yedosi ephezulu yemihla ngemihla engama-3600 mg.

Umthamo weGabapentin wabantwana

IGabapentin yi-FDA evunyiweyo njengonyango lwesibini lokuthimba inxenye kubantwana abaneminyaka emi-3 nangaphezulu ukuxhuzula . Ukusetyenziswa kwe-gabapentin ebantwaneni kuyo nayiphi na imeko yezonyango akuvunyelwanga yi-FDA. Umthamo uya kugqitywa bobabini ubudala bomntwana kunye nobunzima.

Umthamo weGabapentin ngokobudala kubantwana abadala kuneminyaka emi-3
Ubudala (yr)	Umthamo ophakanyisiweyo
3-4 iminyaka	I-40 mg nge-kg (18.2 mg / lb) yobunzima bomzimba eyahlulahlulwe yangamadosi amathathu Ubuninzi: 50 mg nge kg (22.7 mg / lb) yobunzima bomzimba yonke imihla
5-11 iminyaka	I-20-35 mg nge-kg (9.1-15.9 mg / lb) yobunzima bomzimba eyahlulahlulwe yangamadosi amathathu Ubuninzi: 50 mg nge kg (22.7 mg / lb) yobunzima bomzimba yonke imihla
12 yrs okanye ngaphezulu	I-300-600 mg ithathwa kathathu ngemini Ubuninzi: 3600 mg ngosuku

Itshathi yedosi yokulinganisa
Inkcazo	Ubudala	Umthamo osemgangathweni	Ubungakanani benqanaba
Ukuhlutha okungaphelelanga
Iminyaka eyi-12 nangaphezulu	300-600 mg kathathu ngemini	3600 mg ngosuku
Iminyaka 5-11	I-25-35 mg / kg (11.4-15.9 mg / lb) ngemini yahlulwe yaziidosi ezintathu zemihla ngemihla	50 mg / kg (22.7 mg / lb) ngosuku
Iminyaka 3-4	I-40 mg / kg (18.2 mg / lb) ngemini yahlulwe yaziidosi ezintathu zemihla ngemihla	50 mg / kg (22.7 mg / lb) ngosuku
I-neuralgia yangasemva	Iminyaka eyi-18 nangaphezulu	I-300 mg ngosuku 1, 300 mg kabini yonke imihla ngosuku lwe-2, emva koko i-300 mg kathathu ngemini ngosuku lwe-3; idosi inokunyuswa emva komhla we-3 ukuya kuma-600 mg kathathu ngemini	1800 mg ngosuku
Isifo seswekile peripheral neuropathy	Iminyaka eyi-18 nangaphezulu	I-300-1200 mg kathathu ngemini (ngaphandle kwelebheli)	3600 mg ngosuku
Fibromyalgia	Iminyaka eyi-18 nangaphezulu	I-600 mg kabini yonke imihla kunye ne-1200 mg ngexesha lokulala (ngaphandle kwelebheli)	2400 mg ngosuku
Uxhomekeko lotywala	Iminyaka eyi-18 nangaphezulu	300-600 mg kathathu ngemini (ngaphandle kwelebheli)	1800 mg ngosuku

Umthamo weGabapentin wokubanjwa ngokuthe ngqo

IGabapentin yi-FDA evunyiweyo njengonyango lokudibanisa ukubanjwa kwabantu abadala kunye nabantwana abaneminyaka emi-3 ubudala okanye ngaphezulu.

Umgangatho osemgangathweni we-gabapentin kubantu abadala: I-300 ukuya kwi-600 mg ithathwa kathathu ngemini ngomlomo.

Ubuninzi be-gabapentin dosage yabantu abadala: I-3600 mg yonke imihla ngeedosi ezintathu ezahluliweyo.

Izigulana ezinengxaki yokugula (isifo sezintso) -isixa sedosi kunye nohlengahlengiso lokuhamba rhoqo :
- Ukucoca i-Creatinine ye-30-59 ml / min: 200 ukuya ku-700 mg kabini ngemini
- Ukucoca i-creatinine ye-16-29 ml / min: 200 ukuya ku-700 mg kanye ngemini
- Ukucocwa kwe-creatinine ye-15 ml / min okanye ngaphantsi: 100 ukuya ku-300 mg kanye ngemini kunciphise ngokulinganayo (1/15 ngenani elipheleleyo lenani) kunciphiso ngalunye kugonyo lwe-creatinine
- IHemodialysis: idosi ixhomekeke kugqatso lwe-creatinine eqikelelweyo; idosi yokuxabisa eyi-125 ukuya kuma-350 mg inikwa emva kokucofa

Umthamo we-Gabapentin weentlungu zentlungu ngenxa ye-shingles (i-postherpetic neuralgia)

I-Gabapentin yi-FDA evunyiweyo yokunyanga i-postherpetic neuralgia, Oko kukuthi, iintlungu ze-neuropathic ngenxa ye-shingles (herpes zoster).

Umgangatho osemgangathweni we-gabapentin kubantu abadala: I-300 ukuya kwi-600 mg ithathwa kathathu ngemini ngomlomo.

Ubuninzi be-gabapentin dosage yabantu abadala: I-1800 mg yonke imihla ngeedosi ezintathu ezahluliweyo.

Izigulana ezinengxaki yokugula (isifo sezintso): Jonga idosi kwizigulana ezinengxaki yezintso apha ngasentla

Umthamo weGabapentin wentlungu ye-neuropathic

I-Gabapentin ihlala ichazwe ngaphandle kwelebheli ukunyanga iintlungu zentlungu (neuralgia) ngenxa yomonakalo wemithambo-luvo (i-neuropathy), uxinzelelo, okanye ukucaphuka.

Umgangatho osemgangathweni we-gabapentin kubantu abadala: I-300 ukuya kwi-1200 mg ithathwe kathathu ngemini ngomlomo.

Ubuninzi be-gabapentin dosage yabantu abadala: I-3600 mg yonke imihla ngeedosi ezintathu ezahluliweyo.

Izigulana ezinengxaki yokugula (isifo sezintso): Jonga idosi kwizigulana ezinengxaki yezintso apha ngasentla

Umthamo weGabapentin we-fibromyalgia

IGabapentin isetyenziselwa ngaphandle kwelebheli ukunciphisa ukudinwa, ukubonelela ngentlungu, kunye nokuphucula ukulala kwizigulana ezine-fibromyalgia.

Umgangatho osemgangathweni we-gabapentin kubantu abadala: I-600 mg kabini yonke imihla kunye ne-1200 mg ngexesha lokulala.

Ubuninzi be-gabapentin dosage yabantu abadala: 2400 mg yonke imihla.

Izigulana ezinengxaki yokugula (isifo sezintso): Jonga idosi kwizigulana ezinengxaki yezintso apha ngasentla

Umthamo weGabapentin wokuxhomekeka kotywala

IGabapentin yiyo esetyenziswa ngokubanzi ngaphandle kwelebula ukunciphisa ukungalali kunye neminqweno kubantu abanengxaki yokusebenzisa utywala, ngakumbi abo bakwisigaba sokulondolozwa kotywala.

Umgangatho osemgangathweni we-gabapentin kubantu abadala: I-300 ukuya kwi-600 mg ithathwa kathathu ngemini ngomlomo.

Ubuninzi be-gabapentin dosage yabantu abadala: I-1800 mg yonke imihla ngeedosi ezintathu ezahluliweyo.

Izigulana ezinengxaki yokugula (isifo sezintso): Jonga idosi kwizigulana ezinengxaki yezintso apha ngasentla

Umthamo weGabapentin wezilwanyana zasekhaya

Akufanele unike i-gabapentin kwizilwanyana ngaphandle kokuba ugqirha wezilwanyana unike isilwanyana amayeza e-gabapentin. Oogqirha bezilwanyana bahlala beyalela i-gabapentin ukunyanga ukuxhuzula okanye iintlungu ezingapheliyo kwizilwanyana zasekhaya nakwizilwanyana ezikhulu. Umthamo ocetyiswayo yi-5-10 mg ngekhilogram yesisindo somzimba (2.3-4.5 mg / lb) qho kwiiyure ezili-12, kodwa idosi iya kwahluka phakathi koogqirha bezilwanyana. Iidosi zeGabapentin zinokwahluka ukusuka kwi-3 ukuya kwi-11 mg ngeekhilogram (1.4 ukuya kwi-5 mg ngekhilogram) njenge-analgesic ukuya kwi-10 ukuya kwi-30 mg mg ngekhilogram (4.5 ukuya ku-13.6 ngeponti nganye) njenge-anticonvulsant. Njengabantu, idosi inokuqala encinci kwaye inyuke ngokuthe ngcembe de kufikelelwe idosi esebenzayo.

Ungayithatha njani i-gabapentin

I-Gabapentin ihlala ithathwa ngomlomo kathathu ngemini. Kwiimeko ezizodwa , njengaxa ichiza liqala ukuqala okanye kwizigulana ezinengxaki yezintso, i-gabapentin ithathwa kancinci.

Thatha iyeza lakho njengoko kuyalelwe. Idosi inokutshintsha de kufikelelwe kwelona nani liphezulu ledosi.
Ukuba unesathuthwane, sukuvumela ukuba kudlule ngaphezu kweeyure ezili-12 phakathi kwamayeza.
IGabapentin inokuthathwa kunye okanye ngaphandle kokutya.

Ithebhulethi

Gwinya ipilisi yonke ngeglasi yamanzi. Musa ukuyityumza, ukuyaphula, okanye ukuyihlafuna.
Ukuba wophula ithebhulethi iziqwenga ezibini, sebenzisa isiqingatha sesibini njengedosi yakho elandelayo. Lahla nasiphi na isiqingatha sethebhulethi emva kweentsuku ezingama-28.

Iphilisi

Gwinya yonke i-capsule ngeglasi yamanzi. Sukuyivula, uyityumze, okanye uyihlafune.
Ukuba kunzima kakhulu ukuginya i-capsule, isiguli okanye umntu okhathalelayo unokuvula ngononophelo iphilisi kwaye afafaze imixholo kwikomityi encinci yamanzi, ijusi, okanye isosi yeapile kwaye anike idosi ngaloo ndlela.

Ulwelo lomlomo

Linganisa ulwelo lomlomo ngesirinji okanye ikomityi yeyeza eneempawu zemilimitha. Ukunqunyanyiswa ngomlomo kweGabapentin kuhlala kuza nesirinji ye-12 ml.
Xukuza ibhotile evaliweyo kakuhle phambi kokuba uyisebenzise.
Susa ikepusi engqina ubungqina bomntwana kwibhotile.
Qiniseka ukuba iadaptha yesirinji ityhalelwe ekuvulekeni kwebhotile. Ukuba akunjalo, faka ngokupheleleyo iadaptha yesirinji kwindawo evulekileyo yebhotile.
Pushisa isirinji plunger yonke indlela ukuya ezantsi kwincam.
Faka incam yesirinji kwiadaptha.
Jika ibhotile kunye nesirinji ujonge ezantsi.
Cothisa kancinci ulwelo oluchanekileyo kwi-millilitre mark.
Buyisela ibhotile kwindawo emi kuyo.
Susa isirinji kwaye ubeke incam emlonyeni.
Khuphela kancinci imixholo emlonyeni kunye nokuginya.
Khusela ngokukhuselekileyo ikepusi yokhuseleko lomntwana kwibhotile.

Idosi ephosiweyo

Ukuba uphosa idosi ye-gabapentin, thatha idosi ephosiweyo kwakamsinya nje ukuba ukhumbule. Thatha idosi elandelayo ngexesha layo elimiselweyo. Ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uthathe idosi elandelayo ngexesha elimiselweyo. Musa ukuthatha amayeza ongezelelweyo ukwenza idosi ephosiweyo.
Ukuba uthatha i-gabapentin yokuxhuzula, cela ugqirha okanye usokhemesti umkhombandlela wendlela yokuphatha idosi ephosiweyo.

Xa uthatha i-gabapentin, unokufuna ukuqaphela ezi ngcebiso zilandelayo zokhuseleko kunye nokusebenza:

Ngaphambi kokuthatha i-gabapentin, nceda ufunde isiKhokelo seyeza esiza nayo. Buza ikhemesti yakho ikopi ukuba awunayo.
Gcina iyeza kwisikhongozeli esivaliweyo kubushushu begumbi (59˚-86F), kude nobushushu, ukufuma, kunye nokukhanya ngokuthe ngqo.
Gcina ulwelo lomlomo kwifriji (36˚-46F). Musa ukumisa isisombululo.
Ngaphandle kokuba uyalelwe ngugqirha, sukuyithatha i-gabapentin ngotywala okanye amayeza abangela ukozela.
Ukuba uthatha i-antacid ene-aluminium okanye i-magnesium efana neMaalox, Mylanta, okanye iGaviscon, linda ubuncinci iiyure ezimbini ngaphambi kokuba uthathe idosi ye-gabapentin.
Xa uthatha i-gabapentin njengolwelo, sebenzisa isirinji okanye ikomityi enikezelwe iyeza ukulinganisa idosi ngokuchanekileyo. Ukuba ulahlekelwe yisirinji okanye ikomityi, ikhemesti yakho inokubonelela ngento engena endaweni yayo ngaphandle kweendleko.
Kwixesha likaxakeka xa ungenakho ukubuyisela isixhobo sokulinganisa esilahlekileyo, ungasebenzisa okwexeshana icephe lokulinganisa ukuthatha ithamo lokumiswa ngomlomo kwe-gabapentin, kodwa UNGAZE usebenzise icephe otya ngalo okanye ikomityi yokulinganisa. Itispuni iphelele ilingana ne-5 ml yolwelo. Enye icephe epheleleyo ilingana ne-15 ml yolwelo.
Ukuba uthatha ulwelo lomlomo, buza usokhemesti wakho ngethamo elichanekileyo leemililitha.
Kwidosi nganye, rekhoda ixesha kwidayari okanye ishedyuli yokuqinisekisa ukuba idosi elandelayo ayinikwa kwangoko okanye emva kwexesha.
Ukuba ukuthatha i-gabapentin kubangela isisu esibuhlungu, zama ukuyithatha ngokutya.
Ukuba uncelisa, cela ugqirha wakho malunga nokuthatha i-gabapentin.
IGabapentin inokunciphisa ukucinga kwakho, inciphise ukulungelelanisa, kwaye ibangele ukozela, ke musa ukuqhuba, ukusebenzisa oomatshini, okanye ukubandakanyeka kwimisebenzi eyingozi ukuba uziva udiniwe, unesiyezi, okanye ucotha.

I-FAQs zedosi yeGabapentin

Ithatha ixesha elingakanani ukusebenza?

Umthamo wokuqala we-gabapentin uya kuba sezantsi. Inani ledosi kunye nokuphindaphindeka kuya kunyuswa ngokuthe ngcembe yonke imihla de kufikelelwe idosi esebenzayo, inkqubo ebizwa ngokuba yi-titration. Kwiimeko ezininzi, ihlala ithatha iveki enye ukuya kwiiveki ezimbini emva kokuba idosi yokuqala iqaphela iziphumo ze-gabapentin.

Uhlala ixesha elingakanani kwinkqubo ye-gabapentin?

Kubantu abanezintso ezinempilo, i-gabapentin ithathwa rhoqo kwiiyure ezisibhozo. Idosi nganye ifikelela koxinzelelo lwayo emzimbeni kwiiyure ezimbini ukuya kwezintathu.

Izintso zicacisa ngokukhawuleza i-gabapentin emzimbeni. Iqondo apho umzimba ucoca khona i-gabapentin lilinganiswe ngesiqingatha-sobomi, eli lixesha elithathayo ukuze umzimba ucime isiqingatha se-gabapentin emzimbeni. Isiqingatha sobomi se-gabapentin ebantwaneni simalunga neeyure ezintlanu. Kubantu abadala, isiqingatha-sobomi se-gabapentin siiyure ezintlanu ukuya kwezisixhenxe.

Ngenxa yokuba i-gabapentin icocwe zizintso, ichiza lihlala kwinkqubo ixesha elide kwizigulana ezinengxaki yokusebenza kwezintso. Zombini izixa zethamo kunye nobuninzi bethamo kunokufuna ukuba zihlengahlengiswe ngugqirha omiselweyo.

Kwenzeka ntoni ukuba ndiphose idosi ye-gabapentin?

Ukuba uphosa idosi ye-gabapentin, thatha idosi ephosiweyo kwakamsinya nje ukuba ukhumbule. Thatha idosi elandelayo ngexesha layo elimiselweyo. Ukuba phantse lixesha ledosi elandelayo, tsiba idosi ephosiweyo kwaye uthathe idosi elandelayo ngexesha elimiselweyo. Musa ukuthatha amayeza ongezelelweyo ukwenza idosi ephosiweyo. Ukuba uthatha i-gabapentin yokuxhuzula, cela ugqirha wakho, usokhemesti, okanye olunye uqeqesho kwezonyango ngemiyalelo yokuphatha idosi ephosiweyo. Kwizigulana ezinesathuthwane, ukungabikho kwedosi ngaphezulu kweeyure ezili-12 kwandisa umngcipheko wokubanjwa.

Ndiyeka njani ukuthatha i-gabapentin?

IGabapentin akufuneki imiswe ngaphandle kokuba iyalelwe ngugqirha. Izigulana zinokuba neempawu zokurhoxa, ezinje ngokuxhalaba, ukuxhalaba, ukungazinzi, isicaphucaphu, kunye neempawu ezinje ngomkhuhlane, ukuba i-gabapentin iyekwe ngesiquphe emva kokuyithatha ixesha elingaphezu kweeveki ezintandathu. Ukuba i-gabapentin ithathwa ukuthintela ukuxhuzula, ukuyeka ngesiyobisi ngokukhawuleza kunokubangela ukuxhuzula okukhulu. Xa ilixesha lokuyeka ukuthatha i-gabapentin, ugqirha wakho unokucutha ngokuthe ngcembe idosi yakho kwiintsuku ezisixhenxe.

Funa unyango kwangoko ukuba ufumana iziphumo ebezingalindelekanga ezimandundu njengokutshintsha kwemozulu okanye indlela oziphethe ngayo, iingcinga zokuzibulala, iingxaki zokuphefumla, okanye imiqondiso yempendulo yehypersensitivity efana nemingci, ubunzima bokuphefumla, amadlala adumbileyo, okanye umkhuhlane.

Yintoni enokusetyenziswa endaweni yegabapentin?

Ngenxa yeziphumo ebezingalindelekanga, iimeko zonyango, okanye ezinye izizathu, i-gabapentin isenokungakulungeli wonke umntu. Iindaba ezimnandi zezokuba kukho iindlela ezizezinye nezisebenzayo zamayeza amaninzi anyangwa yi-gabapentin. La mayeza abandakanya ii-anticonvulsants, analgesics, tricyclic antidepressants, serotonin reuptake inhibitors (SSRIs) ezinje ICymbalta ( duloxetine ), kunye nokukhetha i-serotonin kunye ne-norepinephrine reuptake inhibitors (SNRIs) ezinje Savella (milnacipran).

Leliphi elonaqondo liphezulu le-gabapentin?

Elona dosi liphezulu le-gabapentin lixhomekeke kwimeko yokuphathwa. Kwiimeko ezininzi, obu bungakanani buphakathi kwe-2,400 mg kunye ne-3,600 mg ngosuku.

Yintoni edibana negabapentin?

Ukutya akuchaphazeli ukubakho kokufumaneka okanye ukusebenza kwe-gabapentin. Nangona kunjalo, ukuba i-gabapentin ibangela iziphumo ebezingalindelekanga ezinje ngesisu esibuhlungu, ukuqunjelwa, okanye urhudo, utshintsho kwindlela otya ngayo lunokufuneka.

Ngenxa yokuba i-gabapentin icothisa umsebenzi kwingqondo, inokubangela iziphumo ezithile ebezingalindelekanga, ezinje ukozela, ukuba nesiyezi, ukulala, ukudinwa, kunye nokulungelelanisa ukungasebenzi kakuhle (ataxia). I-Gabapentin inokusebenzisana nezinto ezifanayo okanye iziyobisi eziphazamisa inkqubo ye-nervous system, enje ngotywala, ii-cannabinoids, ii-sedatives, ii-antihistamines, amayeza oxinzelelo, i-opioids kunye nezinye iziyobisi ezichasene nesifo sokuwa. Ayizizo zonke ezi ziyobisi ekufuneka zithintelwe ngokuthe ngqo, kodwa ukusetyenziswa kwazo kunokuhlengahlengiswa ngugqirha wakho. Xa kuthathwa i-gabapentin kunye nalo naliphi na kula machiza, abaguli kufuneka baliphephe iyeza okanye balumke xa beqhuba, besebenzisa oomatshini, okanye besenza izinto ezinobungozi.

Izigulana kufuneka zilumke xa zithatha ii-antacids eziqukethe i-aluminium okanye i-magnesium salts. I-Aluminium kunye ne-magnesium inokunciphisa uxinzelelo lwe-gabapentin emzimbeni, onokunciphisa ukusebenza kweyeza. Njengomgaqo oqhelekileyo, linda ubuncinci iiyure ezimbini emva kokuthatha i-antacid ngaphambi kokuthatha idosi ye-gabapentin.