IVascepa vs.Lovaza: Umahluko, ukufana, kwaye kukuphi okungcono kuwe
Iziyobisi Vs. UmhloboUkujonga ngokubanzi iziyobisi kunye nolwahluko ophambili | Imiqathango iphathwe | Ukusebenza | Ukuhlawulwa kwe-inshurensi kunye nokuthelekiswa kweendleko | Imiphumela | Ukusebenzisana kweziyobisi | Izilumkiso | FAQ
Ukuba unayo i-triglycerides ephezulu , ugqirha wakho usenokuba ukuxelele ukuba uzame ukutya kunye nokuzilolonga, kwaye mhlawumbi istinin efana neLipitor. Usenokuba ukhe weva nge-omega-3 fatty acids, okanye ioyile yeentlanzi.
IVascepa kunye neLovaza ngamagama amabini amayeza omega-3 amachiza e-acid anyanga amanqanaba aphezulu e-triglyceride. Omabini la mayeza avunyiwe yi-United States yokutya kunye noLawulo lweeDrug (FDA). I-Amarin Pharma, Inc. yenza uVascepa, kunye noGlaxoSmithKline benza igama lophawu lwentengiso lweLovaza. La mayeza asebenza ngeendlela ezininzi zokunciphisa i-triglycerides. Nangona omabini la mayeza ayongezelelo lwe-omega-3, awafani ngokuchanekileyo. Qhubeka nokufunda ukuze ufunde okungakumbi ngeVascepa kunye neLovaza.
Nguwuphi umahluko ophambili phakathi kukaVascepa noLovaza?
IVascepa kunye neLovaza zihlelwa njenge-omega-3 fatty acid lipid-ehlisa iziyobisi. IVascepa okwangoku ifumaneka ngegama lophawu, ngelixa iLovaza ifumaneka kuzo zombini ii-brand kunye ne-generic (i-omega-3-acid ethyl esters). Omabini la machiza avunyiwe ukuba asetyenziswe kubantu abadala kwaye khange afundwe ebantwaneni.
I-Vascepa iqulethe i-icosapent ethyl, okanye i-ethyl ester ye-eicosapentaenoic acid (EPA). IVascepa yehlisa i-triglycerides kwaye inokunceda ekuthinteleni iingxaki zentliziyo kwizigulana ezithile ezisengozini.
ILovaza iqulethe i-omega-3-acid ethyl esters, ubukhulu becala i-eicosapentaenoic acid (EPA) kunye ne-docosahexaenoic acid (DHA). ILovaza yehlisa i-triglycerides kodwa inokunyusa i-cholesterol ye-LDL. Ke ngoko, ifuthe laso kwisifo sentliziyo alaziwa.
| Umahluko ophambili phakathi kweVascepa neLovaza | ||
|---|---|---|
| UVascepa | Lovaza | |
| Iklasi yeziyobisi | I-Omega-3 fatty acid epid-yokunciphisa iarhente | I-Omega-3 fatty acid epid-yokunciphisa iarhente |
| Uhlobo lweBrith / generic | Igama lebrand | Brand kunye generic |
| Ngubani igama eliqhelekileyo? | I-Icosapent ethyl okanye i-ethyl ester ye-eicosapentaenoic acid (EPA) | I-Omega-3-acid ethyl esters: i-eicosapentaenoic acid (EPA) kunye ne-docosahexaenoic acid (DHA) |
| Zeziphi iifom eza nalo iziyobisi? | Njengezingxobo | Njengezingxobo |
| Ithini idosi esemgangathweni? | Iigram ze-4 ngosuku ngeedosi ezahluliweyo (zithathwa kunye nokutya): 2, 1 gram njengezingxobo kabini imihla ngemihla okanye i-4, i-0.5 yeekhilamu zeegram kabini imihla ngemihla Ukuginya iphilisi yonke. Sukuvula, ukuhlafuna, ukunyibilika, okanye ukutyumza. | Iigram ezi-4 ngosuku: 4, 1 gram njengezingxobo kanye ngemini okanye nge-2, 1 yeekhilamu zeekhilamu kabini ngosuku Ukuginya iphilisi yonke. Sukuvula, ukuhlafuna, ukunyibilika, okanye ukutyumza. |
| Lude kangakanani unyango oluqhelekileyo? | Iyahluka | Iyahluka |
| Ngubani oqhelekileyo usebenzisa amayeza? | Abantu abadala | Abantu abadala |
Ngaba ufuna elona xabiso liphezulu ngeVascepa?
Bhalisela iVascepa izilumkiso zamaxabiso kwaye ufumane ukuba amaxabiso atshintsha nini!
Fumana izilumkiso zamaxabiso
Imiqathango ephathwe nguVascepa noLovaza
Zombini iVascepa kunye neLovaza zibonisiwe ukuba zisetyenziswe njengesixhobo sokutya ukunciphisa i-triglycerides kubantu abadala abane-triglycerides ephezulu kakhulu (≥ 500 mg / dL).
IVascepa inokusetyenziswa kunye needosi eziphezulu ze Unyango lwe-statin ukunciphisa umngcipheko weziganeko zentliziyo (ukuhlaselwa yintliziyo, ukubetha, i-coronary revascularization, i-angina engaqinisekanga) kubantu abadala abane-triglycerides ≥ 150 mg / dL abanesifo senhliziyo, okanye abanesifo sikashukela kunye nezinye ezimbini okanye ngaphezulu ezinye izinto ezinobungozi benhliziyo (ngentliziyo isifo).
Iziphumo zeVascepa kunye neLovaza kumngcipheko wepancreatitis kwizigulana ezine-triglycerides ephezulu kakhulu azimiselwanga.
Kananjalo, isiphumo sikaLovaza kwisifo sentliziyo kunye nokufa asaziwa.
| Imeko | UVascepa | Lovaza |
| Isetyenziswe kunye ne-high-dose statin yokunciphisa iingxaki zentliziyo kubantu abadala abane-triglycerides ≥ 150 mg / dL | Ewe | Hayi |
| Isetyenziswe kunye nokutya ukunciphisa amanqanaba e-triglyceride kubantu abadala abane-hypertriglyceridemia (≥500 mg / dL) | Ewe | Ewe |
Ngaba iVascepa okanye iLovaza isebenza ngakumbi?
Kwi ukufunda ngokuthelekisa amayeza omega-3 okunamafutha acid, ababhali baqukumbele ngelithi la mayeza angayithoba kakhulu i-triglycerides ukuya kwinqanaba elinokuthelekiswa kwaye ayanyamezeleka. Amayeza afana neLovaza, ane-DHA, anokunyusa i-LDL cholesterol, enokuba yingxaki kwizigulana ezisemngciphekweni omkhulu wesifo sentliziyo. IVascepa iqulethe i-EPA kuphela kwaye ayichaphazeli amanqanaba e-LDL.
Umboneleli wakho wezempilo unokumisela elona nyango lisebenzayo kuwe. Qhagamshelana nomboneleli wakho wezempilo malunga neengcebiso zonyango. Angathatha isigqibo sokuba uVascepa okanye uLovaza ufanelekile na kuwe xa ujonga iimeko zakho zonyango kunye nembali kunye nawaphi na amayeza owasebenzisayo anokusebenzisana noVascepa okanye uLovaza.
Ufuna elona xabiso liphezulu eLovaza?
Bhalisela izilumkiso zamaxabiso eLovaza kwaye ufumane ukuba amaxabiso atshintsha nini!
Fumana izilumkiso zamaxabiso
Ukufunyanwa kunye nokuthelekiswa kweendleko zeVascepa vs.Lovaza
Izicwangciso ze-inshurensi kunye nezicwangciso zonyango zeMedicare zihlala zigubungela iVascepa neLovaza. Ukuba uthatha uLovaza, ukukhetha uhlobo oluqhelekileyo kungagcina imali ebonakalayo, kuxhomekeke kwisicwangciso sakho.
Ixabiso lokuphuma epokothweni lonikezelo lwenyanga enye lweVascepa lumalunga ne- $ 390, kodwa ungasebenzisa ikhadi lasimahla le-SingleCare ukunciphisa ixabiso ukuya kuthi ga kwi-332 yeedola.
Unikezelo lwenyanga enye lwe-generic ye-Lovaza lumalunga ne- $ 100 ukuba ubhatala uphuma epokothweni. Ikhuphoni yasimahla ye-SingleCare inokuhlisa ixabiso libe ngaphantsi kweedola ezingama-30.
Nxibelelana nesicwangciso sakho seinshurensi ngolwazi oluchanekileyo lokugubungela.
| UVascepa | Lovaza | |
| Ngokuqhelekileyo i-inshurensi? | Ewe | Ewe |
| Ngokuqhelekileyo ihlanganiswe yiCandelo le-Medicare? | Ewe | Ewe |
| Umthamo osemgangathweni | 120, 1 iigram njengezingxobo | 120, 1 iigram njengezingxobo |
| I-Medicare copay eqhelekileyo | $ 1- $ 3 | $ 1- $ 30 |
| Ixabiso elilodwa | $ 332 + | $ 30 + |
Iziphumo eziqhelekileyo ezichaphazelekayo zeVascepa vs.Lovaza
Iziphumo ebezingalindelekanga eziqhelekileyo zeVascepa ziintlungu zemisipha, iedipheral edema (ukudumba kweengalo okanye imilenze), ukuqhina, igawuthi kunye nefibrillisi ye-atrial. Ezinye iziphumo ebezingalindelekanga zinokubandakanya urhudo okanye iintlungu esiswini.
Iziphumo ebezingalindelekanga eziqhelekileyo zeLovaza zi-belching, indigestion, kunye ne-flavour eguqulweyo. Ezinye iziphumo ebezingalindelekanga zinokwenzeka, njengokuqhinwa, ukugabha nokukhawuleza.
Olu aluluhlu olupheleleyo lweziphumo ebezingalindelekanga. Ezinye iziphumo ebezingalindelekanga zinokwenzeka. Nxibelelana neengcali zonyango lwakho uluhlu olupheleleyo lweziphumo ezibi.
| UVascepa | Lovaza | |||
| Imiphumela | Iyasebenza? | Rhoqo | Iyasebenza? | Rhoqo |
| Intlungu yezihlunu | Ewe | ≥3% | Hayi | - |
| Ukudumba kwemida | Ewe | ≥3% | Hayi | - |
| Ukuqunjelwa | Ewe | ≥3% | Ewe | % ayixelwanga |
| Igawuthi | Ewe | ≥3% | Hayi | - |
| I-fibrillation ye-Atriya | Ewe | ≥3% | Ewe | % ayixelwanga |
| Ukucwina | Hayi | - | Ewe | 4% |
| Ukutya | Hayi | - | Ewe | 3% |
| Incasa eguqulweyo | Hayi | - | Ewe | 4% |
Umthombo: DailyMed ( UVascepa ), Yonke imihla ( Lovaza )
Ukudibana kweziyobisi neVascepa vs.Lovaza
Njengoko kuchaziwe kummiselo wolwazi lukaVascepa noLovaza, ezinye izifundo zeklinikhi ene-omega-3 fatty acids ezinje ngeVascepa kunye neLovaza zibonise ixesha elophayo kwizigulana, kodwa ixesha belingekho ngaphezulu kwemida eqhelekileyo, kwaye iziqendu bezingabalulekanga eklinikhi. Ukuba iVascepa okanye i-Lovaza ithathwa kunye ne-anticoagulant (igazi elincinci) okanye amayeza e-antiplatelet, jonga isiguli ukuba siphume igazi. Xelela umboneleli wakho wezempilo malunga nawo onke amayeza owathathayo, kubandakanya amayeza amiselweyo, amayeza e-over-the-counter (OTC), kunye nezongezo zokutya.
| Iziyobisi | Iklasi yeziyobisi | UVascepa | Lovaza |
| Zonke iinkonzo ze-intanethi (fondaparinux) Coumadin (iwarfarin) UEliquis IHeparin Imvelaphi (enoxaparin) Pradaxa Savaysa Xarelto | Iintsholongwane | Ewe | Ewe |
| I-Aspirin Brilinta I-Dipyridamole Iphulo (iprasugrel) IPlavix (clopidogrel) | Iiarhente zeantiplatelet | Ewe | Ewe |
Izilumkiso zikaVascepa noLovaza
- Kwimvavanyo yezonyango elawulwa yi-placebo engaboniyo, uVascepa noLovaza banxulunyaniswa nomngcipheko okhulayo we-atrial fibrillation okanye i-atrial flutter, efuna ukulaliswa esibhedlele. Iziganeko ziphezulu kwizigulana ezinembali ye-atrial fibrillation okanye i-atrial flutter.
- IVascepa kunye neLovaza ziqulathe okunamafutha acid avela kwioyile yeentlanzi. Akucaci ukuba izigulana ezineentlanzi okanye ii-shellfish allergies zisemngciphekweni omkhulu wokuba ne-vascepa okanye i-Lovaza. Qaphela ukuba kunokwenzeka ukuba uxabane, kwaye ufune unyango kwangoko ukuba kukho impendulo.
- Kwezilingo zeklinikhi, uVascepa kunye noLovaza banxulunyaniswa nomngcipheko ophezulu wokopha. Umngcipheko uphezulu kwizigulana ezithatha ii-anticoagulants okanye ii-antiplatelet drug. Jonga icandelo lokunxibelelana neziyobisi ngolwazi oluthe kratya.
- Kwizigulana ezinengxaki yesibindi, jonga i-AST kunye ne-ALT ngexesha lonyango.
- Ukuginya iVascepa okanye iicapsule zeLovaza ziphelele. Musa ukuhlafuna okanye ukutyumza.
- ILovaza inokunyusa amanqanaba e-LDL ye-cholesterol (okanye ye-LDL-C) -ukujonga amanqanaba e-LDL ngexesha lonyango kunye neLovaza.
Imibuzo ebuzwa rhoqo malunga neVascepa vs.Lovaza
Yintoni uVascepa?
I-Vascepa yi-omega-3 fatty acid amayeza amiselweyo aqukethe isithako esibizwa ngokuba yi-EPA (i-ethyl ester ye-eicosapentaenoic acid). UVascepa unceda amanqanaba asezantsi e-triglyceride.
Yintoni uLovaza?
ILovaza yi-omega-3 fatty acid amayeza amiselweyo asetyenziselwa ukuthoba i-triglycerides. ILovaza iqulethe i-eicosapentaenoic acid (EPA) kunye ne-docosahexaenoic acid (DHA).
Ngaba uVascepa noLovaza bayafana?
Omabini la mayeza ayafana. UVascepa kunye neLovaza bobabini yi-omega-3 fatty acid supplements ezifumaneka ngugqirha wokunciphisa i-triglycerides. Omabini la mayeza ane-EPA; ILovaza ikwanayo ne-DHA. Omnye umahluko ucacisiwe apha ngasentla.
Ngaba uVascepa okanye uLovaza ungcono?
IVascepa kunye neLovaza ziyafana nokunciphisa i-triglycerides. Kananjalo banyamezeleka kakuhle. Umahluko omnye kukuba iVascepa ayichaphazeli amanqanaba e-LDL, kodwa iLovaza ingalonyusa amanqanaba e-LDL kwezinye izigulana. Oku kunokuchaphazela ukuba leliphi iyeza elikhethwe ngugqirha wakho, kuxhomekeke kwimingcipheko yesifo sentliziyo.
Ndingayisebenzisa iVascepa okanye iLovaza ngexa ndikhulelwe?
Akukho lwazi lwaneleyo ukufumanisa ukuba iVascepa okanye iLovaza zikhuselekile ngexesha lokukhulelwa. Qhagamshelana nomboneleli wakho wezempilo ukuba ukhulelwe okanye uceba ukukhulelwa.
Ndingayisebenzisa iVascepa okanye iLovaza ngotywala?
Ulwazi oluyalela uVascepa noLovaza alunyanzeli miyalelo malunga nokusetyenziswa kotywala. Qhagamshelana nomboneleli wakho wezempilo malunga nokusetyenziswa kotywala kunye neemeko zakho zonyango.
Ngaba iVascepa iyafana neoyile yentlanzi?
IVascepa inesithako esinye kuphela, i-EPA. Ioyile yeentlanzi, njengeLovaza, ngokubanzi ine-EPA kunye ne-DHA.
I-EPA yehlisa i-triglycerides, kodwa i-DHA inokunyusa i-cholesterol ye-LDL. Kuba iVascepa ine-EPA kuphela, yehlisa i-triglycerides kodwa ayinyusi i-cholesterol ye-LDL.
Ingaba i-Lovaza isezantsi kangakanani i-triglycerides?
Kwi izifundo zonyango , I-Lovaza inciphise i-triglycerides ngomyinge omalunga ne-45%.
Ngaba iVascepa ichasene nokudumba?
Indlela uVascepa asebenza ngayo ukunciphisa i-triglycerides ayiqondakali ngokupheleleyo kodwa inokuthi isebenze ngeendlela ezininzi. Ngo-2018, iAmarin Corporation, umenzi weVascepa, wakhululwa iziphumo zokufunda Ukuqukumbela ukuba uVascepa unciphise ukumakisha kwizigulana ezithile. Nangona kunjalo, iVascepa ayidweliswanga njengechiza elichasayo.
