Ngaba kufuneka uthathe i-Topamax kwimigraines yakho?

Ulwazi lweziyobisi

Njengokuba ukubakho migraines rhoqo kungabi buhlungu ngokwaneleyo, ukuqonda ukuba leliphi iyeza-okanye indibaniselwano yamayeza ilungile kuwe kunokuba ngumceli mngeni omkhulu. Ngombulelo, kukho iindlela zonyango ezininzi ezikhoyo zokuthintela kunye nokuphelisa iintlungu. Ziindaba ezimnandi ezo Izigidi ezingama-38 zaseMelika abahlala ne-migraine.

Olunye lolo khetho, Ngaphezulu ( itopiramate ), Imiselwe ngokubanzi njengeyeza lothintelo lonyango lwe-migraine, ngaphandle kokusetyenziswa kwayo kwasekuqaleni njengechiza le-antiepileptic kubantu abanembali yokuxhuzula.

Ngapha koko, i-topiramate yeyona nto imiselweyo yokuthintela amayeza e-migraine e-United States-ekubeni ivunyiwe kunyango lwe-migraine kubantu abadala kwi-2004, ngokwe UDeborah I. Friedman , MD, uprofesa we-neurology kwiYunivesithi yaseTexas Southwestern Medical Centre kunye nelungu le-American Headache Society.

I-Topamax isebenza njani kwimigraines?

Ngokwenyani, eso siqwenga sephazili asikaziwa.

I-Topiramate isebenza ngeendlela ezahlukeneyo, kwaye akucaci ukuba yeyiphi ebalulekileyo kwimigraine, utshilo uGqirha Friedman, echaza ukuba i-topiramate isebenza ngeendlela ze-sodium kunye ne-calcium emzimbeni, nakwii-receptors ezahlukeneyo apho imithambo-luvo ithumela khona imiqondiso.

Ngokubhekiselele ekufumaneni ukuba i-topiramate ingaphucula iimpawu ze-migraine, yayinokwenzeka ngengozi. UFriedman uthi izigulana zokuxhuzula zichaze ukuphucuka kweempawu zazo ze-migraine ngelixa zithatha i-topiramate kunye nezinye iziyobisi ezifanayo.

Ingakanani i-Topamax ekufuneka ndiyithathile kwimigraines?

Umthamo weTopamax yemigraines ihlala ingaphantsi kunesifo sokuwa, uninzi loogqirha luqala phantsi kwaye lwonyusa inani ngokuthe ngcembe ngexesha, ngokwe UDanny Park , MD, intloko yecandelo le-neurology kwiSibhedlele soMnqophiso waseSweden eChicago.

Umthamo oqhelekileyo uqala ngeepilisi zeemiligram ezingama-25 kabini ngemini, utshilo. Ukunciphisa iziphumo ezibi, ndonyuka ngama-25 eemiligram mihla le ngeveki… [nge] thamo liphezulu lizii-milligram ezili-100 kabini ngemini.

Ziziphi iimpembelelo eziqhelekileyo eziqhelekileyo ze-Topamax kwimigraines?

Nangona i-Topamax inokuphumelela ekunciphiseni ukuphindaphinda kunye nobukrakra be-migraines, loo mpumelelo ihlala iza ngexabiso-abantu abaninzi bayasokola ukunyamezela iziphumo ebezingalindelekanga eziqhelekileyo zeziyobisi, athi uGqirha Friedman angabandakanya:

• ukurhawuzelela, izikhonkwane-kunye-neenaliti imvakalelo emaphethelweni okanye ebusweni
• ukulahleka kwesidlo okukhokelela ekulahlekeni kwesisindo
• ukozela / ukozela
• isicaphucaphu
• Inkungu yengqondo

UGqirha Park wongeza ukuba ezi ziphumo bezingalindelekanga zinokubakho kuluhlu lweedosi ze-topiramate ngokuxhomekeke kwisigulana ngasinye.

Ndinezigulana ezifika kwiimiligram ezili-100 kabini ngemini [ngaphandle kwemiphumela) kwaye ngelishwa ezinye izigulana ezinganyamezeliyo iimiligram ezingama-25 yonke imihla, utsho.

Ngaba i-Topamax inokusebenzela?

Akunyanzelekanga ukuba ube sisifo esingapheliyo semigraine (okt, umntu oneentsuku ezili-15 okanye nangaphezulu ngenyanga, ngokwe Isiseko seAmerican Migraine ) ukuxhamla kunyango lothintelo njengeTopamax. Kodwa uGqirha Friedman uthi izigulana eziphendula iyeza zihlala zinezinye izinto ezifanayo.

Sicinga malunga nonyango lwe-migraine kunyango kubantu abaneentsuku ezine zentloko ngenyanga abanokukhubazeka okunzima kwimigraines, utshilo, oko kuthetha ukuba imigraines ikuthintela ekwenzeni imisebenzi yakho yesiqhelo yemihla ngemihla.

Kwakhona kubandakanywa abantu abanoncedo olwaneleyo kwizonyango ezinobunzima be-migraine kunye nalabo abaneentlobo ezikhethekileyo ze-migraine (njenge hemiplegic okanye inkqubo yengqondo ) nokuba iphindaphindwe kangakanani.

Nangona kunjalo, i-topiramate ayifanelanga wonke umntu. UFriedman uthi ayinakuthathwa ngexa lokukhulelwa, kwaye angacinga kabini ngokumisela umntu onembali yamatye ezintso asekwe kwi-calcium kuba ezinye uphando ibonisa ukuba i-topiramate inokunyusa umngcipheko wokuyiphuhlisa.

Izibonelelo zokuthatha i-Topamax

Kungathabatha ixesha ukuba uve isibonelelo esipheleleyo seTopamax yemigraines-uGqr. UFriedman uthi abantu abaninzi babona ukuphucula kwinyanga yokuqala, kodwa ingaqhubeka nokuphucula unyaka wokuqala. Ukwathi iimvavanyo zeklinikhi ezidlulileyo zibonise iipesenti ezingama-50 zabantu baziva ngcono nge-50% kwi-topiramate, abanye benika ingxelo ngezinga eliphezulu lokuphendula.

Kodwa iziphumo ebezingalindelekanga zezona ziphantsi kakhulu kwi-topiramate; abanye abantu abanakubanyamezela.

Kukuthanda okanye ukuyithiya, utshilo uGqirha Friedman, kwaye ngamanye amaxesha abantu bayoyika ukuyithatha kuba beva ngeziphumo ebezingalindelekanga. Kodwa ayinguye wonke umntu oyifumanayo, ke kubalulekile ukuba uvule ingqondo ngayo.