Iziphumo ebezingalindelekanga zeZoloft kunye nendlela yokuzikhusela

Ulwazi lweziyobisi

Sertraline , eyaziwa njengegama layo, Zoloft , liyeza lonyango elidumileyo elisetyenziselwa ukunyanga ukudakumba , ixhala , Uxinzelelo lwasemva koxinzelelo , ukuphazamiseka koxinzelelo kwezentlalo, ukuphazamiseka kwovalo, kunye nokuphazamiseka kwangaphambi kokuya exesheni (PMDD). Yeyeklasi ye-anti-depressants ebizwa ngokuba yi-serotonin reuptake inhibitors (i-SSRIs) ekhethiweyo, oko kuthetha ukuba iyasebenza ngokunyusa inani le-serotonin kwingqondo. Njengokuba kunokubakho uxinzelelo , Abantu abathatha i-sertraline banokuba neziphumo ezibi. Qhubeka nokufunda ukuze ufunde malunga neempembelelo ze-sertraline, izilumkiso, kunye nokunxibelelana kweziyobisi okunokwenzeka.

ZIQHELEKILEYO: Iinkcukacha zikaSertraline | Iinkcukacha zeZoloft

Iziphumo eziqhelekileyo ezichaphazelekayo ze-sertraline

Ngalo naliphi na iyeza, kuhlala kukho umngcipheko wokufumana amava Iziphumo ezinokubakho ezimbi . Ukwazi xa ufumana iziphumo ebezingalindelekanga, kuyanceda ukuqonda ukuba ichiza kufuneka likwenze uzive njani xa lisebenza ngokuchanekileyo. Kwimeko ye-sertraline, abaguli banokulindela ukuziva bephucukile kwiimvakalelo, ukuthanda ukutya, umgangatho wokulala, inqanaba lamandla, kunye nomdla kubomi bemihla ngemihla. Ngamanye amagama, ukunciphisa iimpawu ezinje ngoxinzelelo kunye noxinzelelo.

I-Sertraline, njengazo zonke ezinye ii-SSRI, inyusa ukujikeleza kwamanqanaba e-serotonin emzimbeni womntu, ukukhuthaza imo yentlalontle kunye nokuvumela abantu abanokudakumba noxinzelelo ukuba bakwazi ukujongana ngcono nemeko yabo yangoku, utshilo URaul Perez-Vazquez , MD, ugqirha wokhathalelo oluphambili lweeNkonzo zeGqirha yaseTenet Florida kunye neZiko lezoNyango laseNtshona Boca.

Ezi zezona ziziphumo zixhaphakileyo ze-sertraline:

• Isicaphucaphu
• Urhudo
• Ukuqunjelwa
• Kunzima ukulala okanye ukulala
• Umlomo owomileyo
• Isitshisa okanye isisu
• Ukuphelelwa ngumdla wokutya
• Ukwehla kobunzima okanye ukutyeba
• Ukuba nesiyezi
• Ukudinwa okugqithisileyo
• Intloko ebuhlungu
• Uvalo
• Utshintsho kwisondo
• Ukungasebenzi kakuhle kwe-Erectile, kubandakanya nokulibaziseka ukunyuka
• Ukubila okugqithisileyo

Iziphumo zecala leZoloft zihamba nini?

Uninzi lweziphumo ebezingalindelekanga ezidweliswe apha ngezantsi zinokuhamba emva kweeveki ezimbalwa ngelixa umzimba uhlengahlengisa.

I-Sertraline ngokwayo ithatha malunga nenyanga ukuqala ukusebenza, kwaye uninzi lweziphumo ebezingalindelekanga ziyancipha emva kokuba umzimba wakho uhlengahlengiso kunyango, utshilo uDavid Nazarian, MD, ugqirha oyintloko I-Concierge yam MD eBeverly Hills.

Ngumbono olungileyo ukulandela iziphumo ebezingalindelekanga ozifumanayo kwaye ugcine unonophelo lwempilo luhlaziywa ukuze ugqirha wakho akwazi ukujonga ngokufanelekileyo iimpendulo kunye nokulungisa amayeza njengoko kufuneka. Okona kubaluleke kakhulu, xelela ugqirha ukuba ngaba iziphumo ebezingalindelekanga zinzima, ziya zisiba mbi, okanye azihambi.

Iziphumo ebezingalindelekanga ezimandundu ze-sertraline

Kukho ezinye eziqhelekileyo, kodwa iziphumo ebezingalindelekanga ezimandundu Inxalenye yeserralraline. Ezi mpawu zilandelayo zifuna unyango kwangoko:

• Ukopha ngokungaqhelekanga okanye ukugruzuka
• Ukuphazamiseka
• Ukudideka
• Umkhuhlane, ukubila, ukungcangcazela
• Ukuba nemibono
• Imihlathi okanye irhashalala
• Ukuphulukana nolungelelwaniso
• Ukuqina kwemisipha okanye ukujija
• Isihlunu, ukugabha, okanye urhudo
• Ukubetha kwentliziyo okukhawulezayo
• Ukuxhuzula
• Ukudumba
• Iingcinga zokuzibulala
• Ingxaki yokuphefumla
• Ukungcangcazela okungalawulekiyo kwilungu lomzimba

Ukurhoxa kukaZoloft

Nangona uninzi lweziphumo ebezingalindelekanga zibuyela umva, akufuneki uyeke ukuthatha i-sertraline ngesiquphe. Endaweni yoko, thetha nomboneleli wezempilo ngaphambi kokuyeka eli yeza ukunqanda iimpawu zokurhoxa. Ugqirha unokwenza isicwangciso sokucothisa amayeza. Iimpawu zokurhoxa zibandakanya:

• Ukucaphuka / ukutshintsha kwemood
• Isicaphucaphu
• Ukuba nesiyezi
• Ukuhlanza
• Ukuphuthelwa
• Amaphupha amabi
• Intloko ebuhlungu
• I-Paresthesias (ukuhlaba, ukuva ulusu kulusu)

Ngokudibeneyo, ezi mpawu zibizwa ngokuba yi-antidepressant discontinuation syndrome, efuna uncedo kwangoko kwezonyango.

Izilumkiso zikaSertraline

Okunye I-FDA izilumkiso zibandakanya izithintelo:

• Izigulana ezinobungozi kwi-sertraline okanye nasiphi na isithako sayo esingasebenziyo
• Abafazi abakhulelweyo okanye abo banokukhulelwa, njengoko i-sertraline inokubangela iingxaki kwiintsana ezisanda kuzalwa emva kokubeleka
• Abasetyhini abancancisayo ukusukela nge-sertraline banokudlula kubisi lwebele
• Abo banengxaki yamehlo esele ibakho enokubenza babe nethuba lokuphuhlisa i-glaucoma, enokubangela iintlungu zamehlo okanye ukungaboni. Uvavanyo lwamehlo lunokufuneka ngaphambi kokufumana i-sertraline prescription.
• Abo banengxaki yokuphazamiseka engqondweni . Ukuba i-sertraline ithathwa ngaphandle kokuzinzisa imeko, isigulana sinokuba semngciphekweni wokutshintshela kwisiqendu se-manic okanye se-hypomanic.

Iingcinga zokuzibulala

Mhlawumbi esona silumkiso sibalulekileyo xa kufuneka uthathe i-sertraline sisakhono sokuzibulala okanye isenzo, ngakumbi kubantu abadala. Zonke i-anti-depressants, enyanisweni, zinesilumkiso esinebhokisi (esona silumkiso siqatha esifunwa yi-FDA) malunga noxinzelelo kunye neengcinga zokuzibulala kunye nokuziphatha.

Ngokutsho komenzi weziyobisi Pfizer , isigulana sinokuzibulala, ngakumbi ekuqaleni konyango kunye naliphi na ixesha apho idosi inyuswe okanye yehlisiwe. I-Pfizer icebisa abaguli ukuba babize umnikezeli wezempilo kwangoko ukuba ubona utshintsho olutsha okanye ngesiquphe kwiimvakalelo, isimilo, okanye iingcinga. Izigulana kunye neentsapho zazo kufuneka zenziwe zazi ngale nto inqabileyo kodwa inokwenzeka. Ngaphandle koko, zonke izigulana kufuneka zilandele rhoqo ugqirha kwaye zibize umnxeba phakathi kwexesha lokuqeshwa ukuba kukho naziphi na kwezi mpawu zilandelayo:

• Ukuziva uphazamisekile, ungazinzanga, unomsindo okanye ucaphuka msinya
• Ukwanda komsebenzi okanye ukuthetha ngaphezu kwesiqhelo
• Uxinzelelo olutsha okanye olubi
• Ukuxhalaba okutsha okanye okuba mandundu okanye ukuhlaselwa kukothuka
• Ingxaki yokulala
• Ukwenza izinto eziyingozi
• Ukwenza ubundlongondlongo okanye ubundlobongela
• Iingcinga ngokuzibulala okanye ukufa
• Imizamo yokuzibulala
• Olunye utshintsho olungaqhelekanga kwindlela yokuziphatha okanye kwimood

Ukozela

Iziphumo ebezingalindelekanga eziqhelekileyo ze-sertraline bubuthongo, obunokuchaphazela amandla akho okuphendula ngokukhawuleza okanye ukwenza izigqibo ezicacileyo. Ngesi sizathu, kukho isilumkiso esomeleleyo sokungaqhubi, ukuqhuba oomatshini abanzima, okanye ukwenza ezinye izinto eziyingozi de ube uyazi ukuba i-sertraline ikuchaphazela njani.

Isifo seSerotonin

Iserotonin syndrome yimeko esongela ubomi enokubangelwa kukuthatha i-sertraline namanye amayeza anyusa imveliso ye-serotonin emzimbeni. La mayeza aquka:

• I-Monoamine oxidase inhibitors (i-MAOIs-musa ukusebenzisa iZoloft kwiintsuku ezili-14 zala mayeza).
• Ezinye ii-SSRI (njengeProzac, Paxil, Celexa, Lexapro)
• I-SNRI (njenge-Effexor, iCymbalta, iPristiq)
• Triptans (Imitrex, Maxalt, njl)
• I-Tricyclic antidepressants (enje nge-Elavil okanye iPamelor)
• Fentanyl
• ILithium
• I-Tramadol
• Zama
• Ibhayiprone
• Wort eSt
• I-fanapt (iloperidone)
• Thorazine (chlorpromazine)

Fumana ikhadi lesaphulelo somntu ongatshatanga

Iimpawu zesifo se-serotonin zibandakanya:

• Umkhuhlane ophezulu
• Utshintsho olukhawulezileyo kwinqanaba lentliziyo okanye uxinzelelo lwegazi
• Ukungalawuleki kwezihlunu zemisipha
• Ukudideka
• Intloko ebuhlungu
• Ubile kakhulu
• Urhudo
• Izihlunu eziqinileyo
• Ukuphulukana nokuqonda (ukudlula)

Ukudibana kweSertraline

Ngaphambi kokuba uthathe iyeza elitsha likagqirha, kuya kufuneka uxele onke amayeza owasebenzisayo ngoku. I-counter-counter, amayeza amiselweyo, kunye neyeza zendalo ezifana nezongezelelo zinokubangela ukusebenzisana kweziyobisi eziyingozi.

I-antipsychotic ethile

Ukudibanisa i-sertraline kunye ne-antipsychotic kwandisa umngcipheko weemeko zentliziyo, kubandakanya ukubanjwa kwentliziyo. Omnye umzekelo yi-Orap (pimozide), iyeza lokuthintela ukungcangcazela rhoqo elinikwa abantu abane-Tourette syndrome. I-Geodon (ziprasidone) kunye ne-droperidol zezinye i-antipsychotic ezinokusebenzisana ne-sertraline.

Abacoci begazi

Ukuthatha i-sertraline enegazi elincinci (i-aspirin, i-Plavix, i-heparin, i-warfarin) inokunyusa umngcipheko wokopha, kubandakanya ukuphuma kweempumlo kunye nesisu kunye nokopha kwamathumbu.

Izidakamizwa ezingekho-steroidal ezichasayo (i-NSAID)

Ukudibanisa i-sertraline kunye Ii-NSAID , njenge-ibuprofen okanye i-naproxen, inokunyusa umngcipheko wezinto ezinzima zesisu, kubandakanya ukopha okusongela ubomi, kunye namanqanaba asezantsi e-sodium.

Utywala

Akufuneki usele utywala ngelixa uthatha i-sertraline njengoko zombini zichaphazela imichiza kwingqondo. Utywala bunokutshintsha ukusebenza kwe-sertraline kwaye bukhokelele kwiziphumo ebezingalindelekanga, kubandakanya iingxaki zokulala nokozela okungaphaya.

Ukongeza, i-Antabuse (i-disulfiram), ephatha ukunxila, ayinakho ukudityaniswa nefomathi ye-sertraline ngenxa yomxholo wotywala kwi-sertraline engamanzi.

Ungaziphepha njani iziphumo ebezingalindelekanga ze-sertraline

Eyona ndlela yokuthintela iziphumo ebezingalindelekanga ze-sertraline kukuthatha amayeza ngokuchanekileyo njengoko kumiselwe ngugqirha kunye nokulungelelaniswa nemiyalelo yomenzi weziyobisi.

Idosi yokuqala ye-sertraline yi-25 ukuya kwi-50 mg ngosuku, enokuthi icothwe kancinci ukuba kukho imfuneko. Iidosi zeSertraline zinokuhlengahlengiswa ngugqirha ngokujonga esondeleyo isigulana kunye nempendulo yakho kunyango. Ngalo lonke ixesha qala i-sertraline ngeyona dosi iphantsi, kwaye wandise kancinci, uphinde uphonononge iimpawu rhoqo, kwaye usebenzise eyona idosi isebenzayo, utshilo uGqirha Perez-Vazquez.

I-Sertraline ingathathwa kunye okanye ngaphandle kokutya, ngokuka Pfizer. Nangona kunjalo, ukuba uhlobo lokugxila okungamanzi kwe-sertraline lumiselwe, kufuneka luxutywe ngamanzi, i-ginger ale, ilamuni okanye i-lime soda, ilamonade, okanye ijusi yeorenji.

Kukho amanye amanyathelo onokuwathatha ukukunceda ukunciphisa iziphumo ebezingalindelekanga ze-sertraline ngelixa ulinde umzimba wakho ukuba uhlengahlengise kunyango olutsha. Olunye uhlengahlengiso kwindlela yokuphila encinci lunokunceda kwiziphumo ebezingalindelekanga ze-sertraline, njengokuthatha iyeza ebusuku ukuthintela ukonqena okanye ukutya ukutya okuncinci rhoqo ukunqanda isicaphucaphu, utshilo uGqirha Nazarian. Ngokumamela umzimba wakho, ukuqaphela iziphumo ebezingalindelekanga, kunye nokwenza ungenelelo olufanelekileyo kwangethuba, ukungonwabi kunokuncitshiswa.

Elinye inyathelo ngamanye amaxesha elihoywa ekuqinisekiseni ukuba amayeza ayasebenza njengoko kufanelekile kukulandela imiyalelo yomenzi ngendlela yokugcina ngocoselelo ngocoselelo. Ngokumalunga ne-sertraline, ibhotile kufuneka ivalwe ngokuqinileyo, igcinwe kwindawo engenakufikelelwa ngabantwana, kwaye igcinwe kubushushu begumbi, i-68 ° F ukuya kwi-77 ° F (20 ° C ukuya kuma-25 ° C).