Codeine vs Hydrocodone: Umahluko ophambili kunye nokufana

Iziyobisi Vs. Umhlobo

I-Codeine kunye ne-hydrocodone ngamayeza amabini anokumiselwa iintlungu. La mayeza anyanga iintlungu ezingaphenduliyo kwii-analgesics eziqhelekileyo ezikhawuntareni. Zombini ziqokelelwe kudidi lwamayeza abizwa ngokuba ziiopioids. Iiopioids ziyaziwa ukuba zinako ukusetyenziswa gwenxa okanye ukuxhatshazwa ngenxa yeziphumo zazo zentlungu. Ke ngoko, amayeza kagqirha ayacelwa ukuba athathe la mayeza. Ngelixa omabini amayeza akwiklasi enye, kukho umahluko wokuxoxa.

Ikhowudi

I-Codeine yi-opioid analgesic ebonakaliswe ukuba ibe yintlungu engathethekiyo kangako apho iintlungu zangaphambili bezingakhange zisebenze. I-Codeine ixutywe kakhulu kwisibindi kwaye ikhutshwe ngeentso. Ityunyiwe kwimetabolite yayo ephambili, i-morphine kunye nemetabolite yesibini, i-hydrocodone kwaye inesiqingatha sobomi esisuswe malunga neeyure ezi-3.
I-Codeine iza kwiipilisi zomlomo kunye namandla e-15 mg, 30 mg, kunye ne-60 mg. Kukho isisombululo somlomo esingama-30 mg / 5 ml ngomlomo. Ihlala ichithwe iiyure ezi-4 njengoko kufuneka.
ICodeine sisiyobisi seShedyuli III okanye V ngokuxhomekeke kubungakanani obunikiweyo. Nokuba kunjalo, oku kubonisa ukuba kukho umngcipheko wokuphathwa gadalala kunye nokuxhomekeka kweli chiza ukuba lisetyenziswe gwenxa.

IHydrocodone

I-Hydrocodone yi-opioid analgesic ethi, ngokungafaniyo nekhowudi, iboniswe ukuba ibe buhlungu ngokuphakathi nangaphakathi. Ngale ndlela, i-hydrocodone inamandla ngakumbi kune-codeine. Nangona kunjalo, i-hydrocodone sisalamane esisondeleyo se-codeine ekwahlengahlengiswa kwisibindi kwaye ikhutshiwe ngezintso. Inemetabolite ephambili ye-hydromorphone kunye nemetabolite encinci ye-dihydrocodeine.
I-Hydrocodone iqulunqwa njengendibaniselwano kunye ne-acetaminophen. Inxalenye yehydrocodone yeli cwecwe iza ngamandla e-2.5 mg, 5 mg, 7.5 mg, kunye no-10 mg. Kukwandiswa iipilisi zehydrocodone ezandisiweyo (iZohydro, iHysingla) ezikumandla ukusuka kwi-10 mg ukuya kwi-120 mg.

Ikhowudi kunye neHydrocodone esecaleni ngokuthelekisa icala

ICodeine kunye neHydrocodone ngamayeza amabini kudidi olunye lweziyobisi. Ukufana kunye nokwahluka kwazo kunokufumaneka apha ngezantsi ukuze ujonge ngakumbi.

Ikhowudi	IHydrocodone
Umiselwe i
Intlungu ethambileyo ukuya kumodareyitha	Ukumodareyitha kwiintlungu ezibuhlungu
Ulwahlulo lweziyobisi
I-Opioid	I-Opioid
Umenzi
Ngokwesiqhelo	Ngokwesiqhelo
Iziphumo eziqhelekileyo
Ukozela Ubumhlophe Ukuba nesiyezi Ukuhlala Ukuqhawukelwa ngumphefumlo Isicaphucaphu Ukuhlanza Ukubila	Ukuqunjelwa Ukozela Ukuba nesiyezi Intloko ebuhlungu Isicaphucaphu Ukuhlanza Pruritus Ukuhamba Ukudinwa Ukugodola
Ngaba ikhona igeneric?
Ikhowudi ligama eliqhelekileyo	IHydrocodone ligama eliqhelekileyo
Ngaba ihlawulwa yi-inshurensi?
Iyahluka ngokomboneleli wakho	Iyahluka ngokomboneleli wakho
Iifom zedosi
Ithebhulethi yomlomo Isisombululo somlomo	Ithebhulethi yomlomo Iifomsile zomlomo Isisombululo somlomo
Ixabiso leMali eliPhakathi
$ 121.91, iipilisi ezingama-60 (30 mg)	317 (iipilisi ezili-100)
Ixabiso lesaphulelo esisodwa
Ixabiso lekhowudi	Ixabiso leHydrocodone
Ukusebenzisana kweziyobisi
Utywala Uxinzelelo lwe-CNS Umxube we-agonist / antagonist analgesics I-Anticholinergics I-MAO inhibitors I-Tricyclic yoxinzelelo I-CYP3A4 kunye ne-CYP2D6 inhibitors I-CYP3A4 inducers	Utywala Uxinzelelo lwe-CNS Umxube we-agonist / antagonist analgesics I-Anticholinergics I-MAO inhibitors I-Tricyclic yoxinzelelo I-CYP3A4 kunye ne-CYP2D6 inhibitors I-CYP3A4 inducers
Ngaba ndingasebenzisa ngelixa ndicwangcisa ukukhulelwa, ukukhulelwa, okanye ukuncancisa?
ICodeine ikuluDidi lokuKhulelwa C. Ngelixa iziphumo ezibi zixeliwe kwizilwanyana, alwenziwanga uphando olwaneleyo ebantwini. Nxibelelana nogqirha malunga namanyathelo oza kuwathatha ngelixa uceba ukukhulelwa. Codeine ayikhuthazwa ngexesha lokuncancisa.	IHydrocodone ikuluDidi lokuKhulelwa C. Ngelixa iziphumo ezibi zixeliwe kwizilwanyana, alwenziwanga uphando olwaneleyo ebantwini. Nxibelelana nogqirha malunga namanyathelo oza kuwathatha ngelixa uceba ukukhulelwa. I-Hydrocodone ayikhuthazwa ngexesha lokuncancisa.

Isishwankathelo

Zombini i-codeine kunye ne-hydrocodone ngamayeza anokusetyenziselwa ukunyanga iintlungu kwiimeko ezahlukeneyo. Nangona kunjalo, i-hydrocodone inamandla ngakumbi kune-codeine. Ngelixa i-codeine inokulungela ngakumbi iimeko zentlungu engaphantsi, i-hydrocodone inokuba ngcono kwiintlungu ezinzima ezifuna ukwandiswa kokukhululwa.
Omabini la mayeza amiselwe ngokwesiqhelo xa iintlungu zingaphendulanga kwezinye iintlungu ezinamandla. Ngesi sizathu, i-codeine kunye ne-hydrocodone zi-DEA amayeza acwangcisiweyo anobungozi bokuxhatshazwa kunye nokuxhomekeka. Omabini la mayeza ayasebenza kwisibindi kwaye unonxibelelwano oluninzi kunye neziyobisi ezininzi. Ngesi sizathu, kubalulekile ukuba ubonane nogqirha wakho ukuze ufumane ukuba leliphi na iyeza le-opioid eliza kulungela wena.