IPristiq vs Effexor: Umahluko, ukufana, kwaye kukuphi okungcono kuwe
Iziyobisi Vs. UmhloboUkujonga ngokubanzi iziyobisi kunye nolwahluko ophambili | Imiqathango iphathwe | Ukusebenza | Ukuhlawulwa kwe-inshurensi kunye nokuthelekiswa kweendleko | Imiphumela | Ukusebenzisana kweziyobisi | Izilumkiso | FAQ
Engaphezulu kwe Abantu abadala baseMelika abazizigidi ezili-16 uxinzelelo (uxinzelelo olukhulu lokudakumba). I-Pristiq kunye ne-Effexor ngamayeza amabini athandwayo aboniswe kunyango loxinzelelo, oluqhelekileyo imeko yempilo yengqondo . I-Effexor XR (ukukhutshwa okwandisiweyo) ikwanyanga ngokubanzi ixhala Ukuphazamiseka, ukuphaphazela, kunye noxinzelelo lwentlalo. Omabini la machiza avunyiwe yi-United States yokutya kunye noLawulo lweeDrug (FDA). I-Wyeth Pharmaceuticals LLC, exhaswa yiPfizer, yenza omabini la machiza kwiifom zegama lophawu.
UPristiq kunye no-Effexor bahlelwa kwiqela lamayeza abizwa ngokuba yi-SNRIs (serotonin-norepinephrine reuptake inhibitors). Basebenza ngokulawula ukuphinda kuthathwe ii-neurotransmitters ezibizwa ngokuba yi-serotonin kunye ne-norepinephrine kwi-CNS (inkqubo ye-nervous system), ngokwenza njalo kuphuculwe iimpawu zoxinzelelo.
Qaphela ukuba igama likaPristiq eliqhelekileyo ngu-desvenlafaxine, kunye negama lika-Effexor eliqhelekileyo yi-venlafaxine. La machiza ayafana kakhulu. Xa i-Effexor (venlafaxine) i-metabolism, ijika ibe yimetabolite esebenzayo-desvenlafaxine.
Nangona uPristiq kunye no-Effexor bobabini be-SNRI, banomahluko, esiza kuthi sichaze apha ngezantsi.
Nguwuphi umahluko ophambili phakathi kukaPristiq kunye no-Effexor?
I-Pristiq kunye ne-Effexor zombini i-SNRI anti-depressants ifumaneka kwi-brand kunye nefom generic. Omabini la machiza avunyiwe ukuba asetyenziswe kubantu abadala.
UPristiq uyafumaneka njengecwecwe lokukhululwa elandisiweyo. Ukulinganisa kungohluka, kodwa idosi esemgangathweni yi-50 mg yonke imihla.
I-Effexor iyafumaneka kwifomathi yethebhulethi, kwaye ikwakhona njengephilisi ekhutshiweyo kunye nefomathi yethebhulethi eyandisiweyo. Umthamo oqhelekileyo uyi-75 okanye i-150 mg yonke imihla (ukwenziwa kweXR).
| Umahluko ophambili phakathi kwePristiq kunye ne-Effexor | ||
|---|---|---|
| Pristiq | Umncedisi | |
| Iklasi yeziyobisi | ISNRI | ISNRI |
| Uhlobo lweBrith / generic | Brand kunye generic | Brand kunye generic |
| Ngubani igama eliqhelekileyo? | I-Desvenlafaxine succinate (desvenlafaxine) | IVenlafaxine hydrochloride (venlafaxine) |
| Zeziphi iifom eza nalo iziyobisi? | Ithebhulethi (ukukhutshwa okude) | Ithebhulethi, iifomsile zokukhululwa ezandisiweyo, iipilisi zokukhululwa ezandisiweyo |
| Ithini idosi esemgangathweni? | 50 mg yonke imihla | Iyahluka: idosi eqhelekileyo yi-XR 75 okanye i-150 mg yonke imihla |
| Lude kangakanani unyango oluqhelekileyo? | Iyahluka | Iyahluka |
| Ngubani oqhelekileyo usebenzisa amayeza? | Abantu abadala | Abantu abadala |
Ngaba ufuna elona xabiso liphezulu kwiPristiq?
Bhalisela izilumkiso zexabiso likaPristiq kwaye ufumane ukuba amaxabiso atshintsha nini!
Fumana izilumkiso zamaxabiso
Imiqathango iphathwe nguPristiq kunye no-Effexor
I-Pristiq (yintoni iPristiq?) Ibonakalisiwe kunyango lwesifo sokudakumba (MDD) kubantu abadala. Ngamanye amaxesha, uPristiq umiselwe off-ileyibheli Olunye usetyenziso.
I-Effexor (ukukhutshwa kwangoko) kubonisiwe ukunyanga uxinzelelo olukhulu lokudakumba. I-Effexor XR (yintoni i-Effexor?) Ibonakalisiwe kukuphazamiseka okukhulu koxinzelelo, ukuphazamiseka koxinzelelo ngokubanzi, ukuphazamiseka koxinzelelo kwezentlalo, kunye noxinzelelo lwexhala.
| Imeko | Pristiq | Umncedisi |
| Uxinzelelo olukhulu lokudakumba | Ewe | Ewe (iifom ze-IR kunye ne-XR) |
| Ukuphazamiseka koxinzelelo ngokubanzi | Ngaphandle kwelebheli | Ewe (ifom yeXR kuphela) |
| Ukuphazamiseka koxinzelelo kwezentlalo (phobia yentlalo) | Ngaphandle kwelebheli | Ewe (ifom yeXR kuphela) |
| Ukuphazamiseka kovalo | Ngaphandle kwelebheli | Ewe (ifom yeXR kuphela) |
Ngaba iPristiq okanye i-Effexor iyasebenza ngakumbi?
UKUYA Uhlalutyo lweemeta ijonge ukhuseleko kunye nokusebenza kwePristiq kunye ne-Effexor. Abaphandi bagqiba kwelokuba omabini la machiza ayafana ngokusebenza kunyango lokudakumba, kunye neziphumo ebezingalindelekanga. Nangona kunjalo, abaguli abathathe uPristiq babene-nausea encinci kunezigulana ezithathe i-Effexor.
Qhagamshelana nomboneleli wakho wezempilo malunga neengcebiso zonyango. Ngumboneleli wakho wezempilo kuphela onokumisela ukuba leliphi iyeza elilunge ngakumbi kuwe, ngokusekwe kwimeko yakho yezonyango kunye nembali, kunye nawo nawaphi na amayeza owathathayo anokuthi asebenzisane noPristiq okanye i-Effexor.
Fumana ikhadi lesaphulelo kwikhemesti
Umyinge kunye neendleko zokuthelekisa iPristiq vs.Expexor
I-inshurensi kunye ne-Medicare Icandelo D izicwangciso zihlala zigubungela iPristiq. Ixabiso eliphuma epokothweni lommiselo oqhelekileyo wama-30, 50 eepilisi zegeneric zimalunga ne- $ 380. Ikhadi lasimahla le-SingleCare linokuzisa ixabiso libe ngaphantsi kweedola ezingama-60.
I-inshurensi kunye ne-Medicare Icandelo D izicwangciso zihlala zigubungela i-Effexor XR (olona hlobo lumiselweyo lwe-Effexor). Ixabiso eliphuma epokothweni lommiselo oqhelekileyo wama-30, 150 mg wee-capsules eziqhelekileyo zi malunga ne- $ 140. Ungasebenzisa ikhadi lasimahla le-SingleCare ukuzisa ixabiso ukuya kuthi ga kwi-15 yeedola.
Njengoko izicwangciso zeinshurensi ziyahluka kwaye zihlala zitshintsha, nxibelelana nesicwangciso sakho seinshurensi yezempilo ngolwazi olukhoyo ngoku
| Pristiq | Umncedisi | |
| Ngokuqhelekileyo i-inshurensi? | Ewe | Ewe |
| Ngokuqhelekileyo ihlanganiswe yiCandelo le-Medicare? | Ewe | Ewe |
| Umthamo osemgangathweni | Iipilisi zokukhululwa ezandisiweyo ezingama-30 mg | I-30, i-150 mg yeepilisi ezandisiweyo zokukhutshwa |
| I-Medicare copay eqhelekileyo | $ 1- $ 7 | $ 0- $ 20 |
| Ixabiso elilodwa | $ 60- $ 80 | Iidola ezili-15- $ 40 |
Iziphumo eziqhelekileyo ezichaphazelekayo zePristiq vs Effexor
Iziphumo ebezingalindelekanga ezixhaphakileyo zePristiq sisicaphucaphu, isiyezi, ukungalali, ukubila kakhulu, ukuqhina, ukulala, ukunciphisa ukutya, ixhala kunye neengxaki zesini samadoda.
Iziphumo eziqhelekileyo ezichaphazelekayo ze-Effexor XR ziyisicaphucaphu, ukulala, umlomo owomileyo, ukujuluka, iingxaki zesini, ukunciphisa ukutya kunye nokuqhaqha.
Ezinye iziphumo ebezingalindelekanga zinokwenzeka. Nxibelelana neengcali zonyango lwakho uluhlu olupheleleyo lweziphumo ezibi.
| Pristiq | Umncedisi * | |||
| Imiphumela | Iyasebenza? | Rhoqo | Iyasebenza? | Rhoqo |
| Isicaphucaphu | Ewe | 22% | Ewe | 30% |
| Umlomo owomileyo | Ewe | Shumi elinanye% | Ewe | Shumi elinantlanu% |
| Ukuqunjelwa | Ewe | 9% | Ewe | 9% |
| Ukunciphisa ukutya | Ewe | 5% | Ewe | 10% |
| Ukuba nesiyezi | Ewe | 13% | Ewe | 16% |
| Ukulala | Ewe | 4% | Ewe | Shumi elinantlanu% |
| Ukuphuthelwa | Ewe | 9% | Ewe | 18% |
| Ukubila | Ewe | 10% | Ewe | Shumi elinanye% |
| Ukuncipha kwe-libido | Ewe | 4% | Ewe | 5% |
| Iingxaki zobume | Ewe | 1% | Ewe | 10% |
| Ukungasebenzi / ukungasebenzi kakuhle kwe-erectile | Ewe | 3% | Ewe | 5% |
* Iipesenti ezidwelisiweyo ze-Effexor XR, ulwakhiwo oluqhelekileyo olumiselweyo lwe-Effexor
Umthombo: DailyMed ( Pristiq ), Yonke imihla ( Umncedisi XR)
Ukudibana kweziyobisi nePristiq vs Effexor
Sebenzisa i-SNRI antidepressants ene-MAO inhibitors kunokunyusa umngcipheko isifo se-serotonin , enokusongela ubomi. IPristiq okanye i-Effexor kufuneka yohlulwe kwi-MAOI ngeentsuku ezisixhenxe ukuya kwezili-14, kuxhomekeke kweliphi iyeza eliyekiswa kuqala. UPristiq okanye u-Effexor akufuneki athathwe namanye amayeza anyusa amanqanaba e-serotonin, njengezinye i-SNRI okanye i-SSRI anti-depressants, i-triptans ye-migraines, kunye ne-opioids, ngenxa yesizathu esifanayo. I-dextromethorphan efumaneka eRobitussin-DM kunye nokunye ukukhwehlela kunye neemveliso ezibandayo, kufuneka kuthintelwe, njengoko kunokubangela neserotonin syndrome xa idityaniswe nePristiq okanye i-Effexor.
Ezinye iziyobisi ezinokuthi zisebenzisane nePristiq okanye i-Effexor zibandakanya ii-NSAIDs (iziyobisi ezingezizo ezokulwa nokudumba) ezinje nge-aspirin okanye ibuprofen, kunye nee-anticoagulants (igazi elincinci) njenge-warfarin. Gwema utywala xa uthatha iPristiq okanye i-Effexor.
Ukuba uPristiq uthathwe kunye neyeza elixutywe ne-enzyme ebizwa ngokuba yi-cytochrome P 2D6, elinye iyeza linokwakheka kumanqanaba aphezulu kakhulu kwaye anokuba yityhefu. Uhlengahlengiso lwesilinganiselo lunokufuneka. I-Effexor ayinalo olu nxibelelwano.
Olu ayilo luhlu lupheleleyo lokunxibelelana kweziyobisi. Nxibelelana nomboneleli wakho wezempilo uluhlu olupheleleyo lokudibana kwamachiza.
| Iziyobisi | Iklasi yeziyobisi | Pristiq | Umncedisi |
| Isocarboxazid Umgca we-Linezolid IPhenelzine I-Selegiline Tranylcypromine | I-MAOIs (i-monoamine oxidase inhibitors) | Ewe | Ewe |
| Rizatriptan ISumatriptan Zolmitriptan | IiTriptans | Ewe | Ewe |
| Wort eSt | Isongezelelo | Ewe | Ewe |
| Ikhowudi IHydrocodone Imofini Oxycodone I-Tramadol | Iipioids | Ewe | Ewe |
| I-Dextromethorphan (kuninzi lokukhohlela kunye neemveliso ezibandayo) | Isikhohlisi esisicinezelayo | Ewe | Ewe |
| I-Desvenlafaxine Duloxetine IVenlafaxine | I-SNRI yoxinzelelo | Ewe | Ewe |
| Citalopram I-Escitalopram IFluoxetine IFluvoxamine Paroxetine Sertraline | I-SSRI yoxinzelelo | Ewe | Ewe |
| Amitriptyline Desipramine Imipramine Umgca weNortriptyline | I-Tricyclic yoxinzelelo | Ewe | Ewe |
| I-Aspirin Ibuprofen Meloxicam UNabumetone INaproxen | Ii-NSAID (iziyobisi ezichasayo ezingasebenziyo) | Ewe | Ewe |
| IWarfarin | I-Anticoagulant | Ewe | Ewe |
| Phentermine | Ummeli wokuphulukana nobunzima | Ewe | Ewe |
| Atomoxetine Imitha Nebivolol IPerphenazine Itolterodine | Iziyobisi ezenziwa zenziwe yi-enzyme CYP2D6 | Ewe | Hayi |
Izilumkiso zikaPristiq kunye no-Effexor
Zonke i-anti-depressants, kubandakanya uPristiq kunye no-Effexor, banesilumkiso esibhokisi sokuzibulala. Isilumkiso esibhokisi sisilumkiso esinzulu esifunwa yi-FDA. Abantwana, abakwishumi elivisayo, kunye nabantu abadala abancinci (ukuya kuthi ga kwi-24 iminyaka) abathatha iziyobisi ezichasene noxinzelelo banomngcipheko okhulayo wokucinga ngokuzibulala kunye nokuziphatha. Zonke izigulana zivuliwe amayeza antidepressant kufuneka ijongwe ngononophelo.
Ezinye izilumkiso zibandakanya:
- UPristiq kunye no-Effexor abavunyelwanga ukunyanga izigulana zabantwana.
- Iserotonin syndrome yimeko engxamisekileyo, esongela ubomi ebangelwa kukwakhiwa kweserotonin eninzi. Izigulana ezithatha iPristiq okanye i-Effexor kufuneka zijongwe ngononophelo kwiimpawu kunye neempawu zesifo se-serotonin, ezinje ngombono, ukuxhuzula, utshintsho kuxinzelelo lwegazi kunye nokuphazamiseka. Izigulana kufuneka zifune unyango olukhawulezileyo ukuba kukho naziphi na kwezi mpawu. Izigulana ezithatha amanye amachiza anyusa amanqanaba e-serotonin (triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, dextromethorphan, amphetamines, iSt.
- UPristiq okanye u-Effexor banokuphakamisa uxinzelelo lwegazi. Jonga uxinzelelo lwegazi rhoqo. Ukuba unoxinzelelo lwegazi oluphezulu okanye iingxaki zentliziyo, nxibelelana nomboneleli wakho wezempilo ngaphambi kokuba uthathe iPristiq okanye iEffexor.
- I-SNRI inokunyusa umngcipheko wokopha. Umngcipheko ukwanda ngokusetyenziswa ngokuhambelana kwe-aspirin, ii-NSAID, okanye i-warfarin.
- Ukwenza kusebenze i-mania okanye i-hypomania inokwenzeka. Kwizigulana ezinengxaki yokuphazamiseka kwengqondo, i-anti-depressant inokuthintela isiqendu esidibeneyo / somntu.
- Gwema i-SNRIs okanye uyisebenzise ngononophelo kwizigulana ezinganyangekiyo ii-angles ezincinci zomzimba (i-angle-closure glaucoma). Buza umboneleli wakho wezempilo ukuba usemngciphekweni.
- Xa uyeka ukuthatha iPristiq okanye i-Effexor, cela umboneleli wakho wezempilo ukuba abe neshedyuli yokuthinta. Ukuyekiswa ngesiquphe kunokubangela iimpawu zokurhoxa ezinje ngesicaphucaphu, ukungcangcazela, ukudideka, kunye nokubanjwa. Ukunciphisa idosi ngokuthe chu kunokunceda ukunqanda ezi mpawu.
- I-Hyponatremia (amanqanaba asezantsi e-sodium) ngenxa yesifo se-secretion ye-antidiuretic hormone secretion (SIADH) enokwenzeka. Izigulana zinokuba neentloko ezibandayo, ubunzima bokugxila, ukungakhubeki kwimemori, ukudideka, ubuthathaka kunye nokungazinzi, okunokubangela ukuwa. Iimeko ezinzima kakhulu zinokwenzeka. Izigulana kufuneka zifune unyango olukhawulezileyo ukuba zikhona iimpawu, kwaye ziyeke i-SNRI.
- Sukuqhuba okanye usebenze ngoomatshini de ube uyazi ukuba iPristiq okanye iEffexor ikuchaphazela njani.
- Thetha nomboneleli wakho wezempilo malunga nokusebenzisa iPristiq okanye i-Effexor ukuba unembali yokubanjwa.
- Kwiimeko ezinqabileyo, kuye kwakho iingxelo zokukhawuleza kunye neempendulo ze-allergies / systemic anaphylaxis reaction okanye i-angioedema. Ukuba ufumana ukukhawuleza okanye iimpawu zokungabikho komzimba, yeka ukuthatha iPristiq okanye i-Effexor uze ufune unyango ngokukhawuleza. Musa ukuthatha iPristiq okanye i-Effexor ukuba uxabisa nasiphi na isithako.
- Iimeko eziqhelekileyo zesifo semiphunga kunye ne-eosinophilic pneumonia zidibene nala mayeza. Ukuba uthatha uPristiq okanye u-Effexor kwaye uphefumla kancinci, ukhohlela, okanye ungonwabisi esifubeni, funa unyango kwangoko.
- I-Pristiq okanye i-Effexor kufuneka isetyenziswe kuphela ekukhulelweni ukuba inzuzo kumama inkulu kunengozi kumntwana. Ukuyeka iyeza kunokubangela ukuphinda ubenokudakumba okanye uxinzelelo. Ke ngoko, abaguli kufuneka bavavanywe kwimeko nganye-nganye. Umboneleli wakho wezempilo unokuwuthelekisa umngcipheko xa kuthelekiswa nezibonelelo zokusebenzisa i-SNRI ngexesha lokukhulelwa. I-Neonates evezwe kwii-SNRI kwi-trimester yesithathu iphuhlise iingxaki ezifuna ukulaliswa esibhedlele ixesha elide, inkxaso yokuphefumla, kunye nokondla ityhubhu. Ukuba sele ukwiPristiq okanye i-Effexor kwaye ufumanisa ukuba ukhulelwe, nxibelelana nomboneleli wakho wezempilo kwangoko.
- UPristiq: Gwinya ipilisi yonke, ngamanzi. Musa ukuhlafuna, ukutyumza, ukunyibilikisa, okanye ukwahlula amacwecwe.
- I-Effexor XR: Ukuginya iphilisi yonke ngamanzi. Musa ukwahlula, ukutyumza, ukuhlafuna, okanye ukubeka icapsule emanzini. Ngenye indlela, unokuvula i-capsule, ufefe iziqulatho kwi-spoonful ye-appleauce, kwaye ngokukhawuleza uginye umxube, ulandelwe ngokusela iglasi yamanzi.
Imibuzo ebuzwa rhoqo malunga nePristiq vs Effexor
Yintoni iPristiq?
UPristiq yi-SNRI yoxinzelelo. UPristiq uphatha uxinzelelo kubantu abadala. Igama eliqhelekileyo ngu-desvenlafaxine.
Yintoni i-Effexor?
I-Effexor ikwayi-SNRI yoxinzelelo. U-Effexor uphatha uxinzelelo kubantu abadala. I-Effexor XR (ukukhutshwa okwandisiweyo) inyanga uxinzelelo, uxinzelelo lwentlalo, ukuphazamiseka kovalo, kunye noxinzelelo ngokubanzi loxinzelelo. Igama eliqhelekileyo le-Effexor yi-venlafaxine.
Ngaba uPristiq no-Effexor bayafana?
Amayeza afana kakhulu. Xa i-Effexor i-metabolism emzimbeni, ijika ibe yi-desvenlafaxine, isithako esisebenzayo sePristiq. La machiza mabini ayafana kodwa aneeyantlukwano ezithile, ezinje ngedosi, ixabiso, amaqondo eziphumo ebezingalindelekanga, kunye nokudibana kweziyobisi.
Ngaba uPristiq okanye u-Effexor ungcono?
Omabini la machiza ayafana ngokwempumelelo. Umboneleli wakho wezempilo angakukhokela malunga nokuba leliphi ichiza elifanelekileyo kuwe.
Ndingayisebenzisa iPristiq okanye i-Effexor ngelixa ndikhulelwe?
Qhagamshelana nomboneleli wakho wezempilo ngengcebiso. Uya kujonga izibonelelo ze ukuthatha i-antidepressant vs.umngcipheko kusana . I-Neonates evezwe kuthomalaliso ezithile, kubandakanya ii-SNRIs okanye ii-SSRI (i-serotonin reuptake inhibitors ekhethiweyo njengeProzac), kwikota yesithathu yokukhulelwa, baye baneengxaki ezinkulu.
Ukuba sele ukwiPristiq okanye i-Effexor kwaye ufumanisa ukuba ukhulelwe, nxibelelana ne-OB-GYN yakho kwangoko ukuze ufumane iingcebiso. Ukuba kunjalo ukuncancisa , Nxibelelana ne-OB-GYN yakho ngokunjalo.
Ndingayisebenzisa iPristiq okanye i-Effexor ngotywala?
UPristiq okanye u-Effexor akufuneki athathwe ngotywala kuba indibaniselwano inokonyusa umngcipheko woxinzelelo lokuphefumla (ukuphefumla okucothayo, ukungafumani oksijini yaneleyo) kunye nokunyusa ukudinwa kunye nokozela, kunye nokuphazamisa ukuphaphama. Indibaniselwano inokubangela uxinzelelo kunye noxinzelelo.
Ngaba uPristiq uyanceda ngoxinzelelo?
Nangona uPristiq eboniswa kuphela ukunyanga uxinzelelo, abanye oogqirha bayayichaza ngaphandle kwelebheli yoxinzelelo. Nangona kunjalo, kwi Uvavanyo lwezonyango , Iipesenti ezi-3 zezigulana ezithathe iPristiq 50 mg (idosi ekhuthazwayo) ezinamaxhala njengeziphumo ebezingalindelekanga. Abanye abantu kufuneka bazame amayeza ahlukeneyo ukubona ukuba yeyiphi eyona isebenzayo. Qhagamshelana nomboneleli wakho wezempilo ngolwazi olungakumbi.
Ngaba uPristiq sisimo esisimamisi?
Iziyobisi ezichazwe njengeziqinisi zemood zihlala zisetyenziselwa ukunyanga ukuphazamiseka kwengqondo. UPristiq ubonakalisiwe ukunyanga uxinzelelo. Ukuthatha iPristiq kunokwenza imood yakho izive izinzile, kodwa ayicalulwa njengemoodizer. UPristiq yi-SNRI yoxinzelelo.
Ngaba i-venlafaxine yi-SNRI?
Ewe. I-Effexor (venlafaxine) yi-SNRI. Ezinye ii-SNRI zoxinzelelo zibandakanya iPristiq (desvenlafaxine), Fetzima (levomilnacipran), kunye ICymbalta (duloxetine).
