IHydrocodone vs iOxycodone: Umahluko, ukufana, kwaye kukuphi okungcono kuwe
Iziyobisi Vs. UmhloboUkujonga ngokubanzi iziyobisi kunye nolwahluko ophambili | Imiqathango inyangwa | Ukusebenza | Ukuhlawulwa kwe-inshurensi kunye nokuthelekiswa kweendleko | Imiphumela | Ukusebenzisana kweziyobisi | Izilumkiso | FAQ
IHydrocodone kunye ne-oxycodone zimbini opioid amayeza amiselweyo aboniswe kunyango lweentlungu eziphakathi ukuya kwezintlungu, zihlala zintlungu. Omabini la machiza ahlelwa njengee-narcotic, oko kuthetha ukuba bayakhobokisa kwaye banamandla aphezulu okuphathwa gadalala. Omabini la machiza asebenza ngokuzibophelela kwizamkeli zentlungu, ezibizwa ngokuba zii-mu receptors, kwingqondo, ethoba amandla okanye ibhloka imiqondiso yeentlungu, kunye neziphumo zokuthomalalisa iintlungu. Ngenxa yokuba omabini la mayeza anamandla, aqhelekileyo asetyenziswa emva kotyando, okanye kwiimeko apho kuthomalalisa iintlungu kancinci bekungayi kusebenza okanye kunganyamezeleka.
Nguwuphi umahluko ophambili phakathi kwehydrocodone kunye ne-oxycodone?
Zininzi iindlela ezahlukeneyo zehydrocodone kunye ne-oxycodone. Omabini la machiza ngamayeza entlungu eShedyuli II; oku kuthetha ukuba ichiza linokubakho amandla aphezulu okuphathwa gadalala.
I-Hydrocodone (i-Hydrocodone coupons | Yintoni i-Hydrocodone?) Eyona nto ifunyanwa njengamagama egama uNorco okanye i-Vicodin, equlathe i-hydrocodone ngokudibanisa ne-Tylenol (acetaminophen, edla ngokufinyezwa njenge-APAP). I-Hydrocodone / i-APAP inokufumaneka kwifom yepilisi kunye nefom ye-liquid. I-Hydrocodone inokufumaneka ngokudibanisa ne-ibuprofen, kunye nokudibanisa amayeza okukhwehlela, njenge-Hycodan isiraphu okanye iipilisi (i-hydrocodone / i-homatropine) okanye ukumiswa kwe-Tussionex (i-hydrocodone / i-chlorpheniramine). Yedwa, i-hydrocodone inokufumaneka kwiziyobisi ezandisiweyo ezikhutshiweyo iZohydro ER (eyandisiweyo-yokukhululwa) okanye iHysingla ER.
I-Oxycodone (i-Oxycodone coupons | Yintoni i-Oxycodone?) Iqhele ukubekwa yodwa, njenge-generic ye-OxyIR (ukukhutshwa kwangoko). Kufunyenwe yedwa kwiziyobisi ezisebenza ixesha elide ezibizwa ngokuba yi-OxyContin. I-Oxycodone ikwafumaneka ngokudibeneyo, njengePercocet, equlathe i-oxycodone kunye neAPAP.
Omabini la machiza ayashiyana ngokomyinge ngokweminyaka nangemeko kwaye ngokubanzi amiselwe kweyona dosi iphantsi ngelixesha lifutshane. Onke amazwe anemithetho malunga nemigqaliselo ye-opioid, ngenxa yokuba namandla okuxhatshazwa.
| Umahluko ophambili phakathi kwehydrocodone kunye ne-oxycodone | ||
|---|---|---|
| IHydrocodone | Oxycodone | |
| Iklasi yeziyobisi | I-Opiate (narcotic) iintlungu | I-Opiate (narcotic) iintlungu |
| Uhlobo lweBrith / generic | Brand kunye generic | Brand kunye generic |
| Ngubani igama eliqhelekileyo? Ngubani igama lophawu? | Oluqhelekileyo: hydrocodone, hydrocodone / APAP, njl. Igama lebrand: Zohydro ER, Hysingla ER Igama lebrand: ngokudibeneyo neAPAP: Norco, Lortab, Vicodin | Eqhelekileyo: i-oxycodone, i-oxycodone / i-APAP, njl. Igama lebrand: OxyIR, OxyContin Igama lebrand: ngokudibeneyo neAPAP: Percocet |
| Zeziphi iifom eza nalo iziyobisi? | Ithebhulethi, ithebhulethi ekhululweyo, isiraphu njengesiyobisi esidibeneyo | Ithebhulethi, ithebhulethi ekhulisiweyo, isisombululo somlomo |
| Ithini idosi esemgangathweni? | Umzekelo: IHydrocodone / APAP 5/325 mg: 1-2 ithebhulethi (ii) iiyure ezi-4 ukuya kwezi-6 njengoko kufuneka iintlungu (ubuninzi beepilisi eziyi-8 ngosuku) | Umzekelo: Ithebhulethi yokukhululwa kwangoko: 5 ukuya kwi-15 mg qho kwiiyure ezi-4 ukuya kwezi-6 njengoko kufuneka I-OxyContin: 20 mg rhoqo kwiiyure ezili-12 |
| Lude kangakanani unyango oluqhelekileyo? | Ixesha elifutshane, linokusetyenziswa ixesha elide ngokusekwe kwimeko yokuphathwa (njengentlungu engapheliyo) kunye nempendulo | Ixesha elifutshane, linokusetyenziswa ixesha elide ngokusekwe kwimeko yokuphathwa (njengentlungu engapheliyo) kunye nempendulo |
| Ngubani oqhelekileyo usebenzisa amayeza? | Abantu abadala | Abantu abadala |
Imiqathango ephathwa yi-hydrocodone kunye ne-oxycodone
IHydrocodone kunye ne-oxycodone zombini zibonisiwe ulawulo lweentlungu Oko kunzima ngokwaneleyo ukufuna i-opioid, apho ezinye iindlela zonyango (ezingezizo ii-opioids) azonelanga okanye zinganyamezelwa
| Imeko | IHydrocodone | Oxycodone |
| Ulawulo lweentlungu ezinzima ngokwaneleyo ukufuna i-opioid analgesic kwaye loluphi olunye unyango olungonelanga | Ewe | Ewe |
Ngaba i-hydrocodone okanye i-oxycodone isebenza ngakumbi?
Kwindawo engaboniyo, elawulwa yi-placebo ukufunda ye-hydrocodone vs i-oxycodone kwindawo yokubeka igumbi likaxakeka, iintlungu zazifana, kwimizuzu engama-30 nakwimizuzu engama-60 kuzo zombini i-hydrocodone okanye i-oxycodone. Omabini la mayeza ayeneziphumo ebezingalindelekanga ezifanayo, kunye nehydrocodone ebangela ukuqhina kancinci kune-oxycodone.
Enye ukufunda ubonise i-hydrocodone / i-APAP kunye ne-oxycodone / i-APAP ukuba ibe neziphumo ezifanayo ngokubhekisele kwintlungu, kodwa loo oxycodone / APAP ibinamandla aphindwe kali-1.5 kune hydrocodone / APAP.
Zombini i-hydrocodone kunye ne-oxycodone zizipilisi zentlungu ezomeleleyo ezinamandla okuphathwa gadalala, zisetyenziswa xa iipilisi zeentlungu eziqatha zingakhange zibonelele ngoncedo olusebenzayo lwentlungu, okanye azinakunyamezeleka. Olona nyango lusebenzayo kufuneka lumiselwe ngugqirha wakho kuphela, oya kuthi ajonge umfanekiso opheleleyo weemeko zakho zonyango, ezembali, kunye namanye amayeza owathathayo.
Umyinge kunye neendleko zokuthelekisa i-hydrocodone vs i-oxycodone
Ngenxa yemithetho eyahlukeneyo yelizwe, ukuba ufumana i-opioid okokuqala, kunokwenzeka ukuba ufumane ubuncinci.
Umyalelo oqhelekileyo wamacwecwe angama-20 e-hydrocodone-acetaminophen axabisa ngaphezulu kweedola ezili-100. Nge-singleCare coupon, i-genic Vicodin okanye i-Norco inokuqhuba i-26- $ 41 yeedola. Ummiselo oqhelekileyo weepilisi ezingama-20 ze-oxycodone-acetaminophen ngama- $ 25- $ 50. Ixabiso lokuphuma epokothweni li- $ 10- $ 15 ngekhuphoni ye-SingleCare.
Fumana ikhadi lesaphulelo somntu ongatshatanga
| IHydrocodone | Oxycodone | |
| Ngokuqhelekileyo ihlawulwa yi-inshurensi? | Ewe | Ewe |
| Ngokuqhelekileyo ihlanganiswe yiCandelo le-Medicare? | Ewe | Ewe |
| Umthamo osemgangathweni | # 20, hydrocodone / APAP 5/325 mg iipilisi | # 20, iipilisi ze-oxycodone / APAP 5/325 mg |
| Uhlobo lweMedical Medicare Part D | $ 3-73 | $ 3-90 |
| Ixabiso elilodwa | $ 26- $ 41 | $ 10- $ 15 |
Iziphumo eziqhelekileyo ezichaphazelekayo ze-hydrocodone vs i-oxycodone
Iziphumo zixhaphakileyo zehydrocodone kukukhanya okungapheliyo, isiyezi, isisu, isicaphucaphu kunye nokugabha. Ezinye iziphumo ebezingalindelekanga zinokubandakanya ukuqhina, uxinzelelo, irhashalala, ukonqena, kunye nokuxhomekeka.
Iziphumo eziqhelekileyo ze-oxycodone isicaphucaphu, ukuqhina, ukugabha, intloko ebuhlungu, pruritus (ukurhawuzelela), ukuqaqanjelwa sisisu, ukuba nesiyezi, ukuba buthathaka kunye nokozela. Ezinye iziphumo ebezingalindelekanga zinokubandakanya ukubetha, umlomo owomileyo, unxunguphalo, irhashalala kunye nokuxhomekeka.
Ezinye iziphumo ebezingalindelekanga zinokwenzeka. Qhagamshelana nomboneleli wakho wezempilo ngolwazi oluthe kratya malunga neziphumo ezibi.
Ukudibana kweziyobisi kwe-hydrocodone vs i-oxycodone
Ukuthatha i-hydrocodone okanye i-oxycodone ngamayeza athile ahlengahlengiswayo yi-enzyme ebizwa ngokuba yi-CYP3A4 okanye i-CYP2D6 inokubangela ukuhlangana kweziyobisi. La machiza ayaziwa njenge-enzyme inhibitors kwaye aquka ii-macrolide antibiotics, ii-azole antifungals, kunye ne-protease inhibitors. Ukuzisebenzisa kunye nehydrocodone okanye i-oxycodone kunokubangela amanqanaba aphezulu e-opioid, anokuba yingozi kakhulu.
Amanye amachiza, aziwa njenge-inducers, aneziphumo ezichaseneyo, ukwehlisa inqanaba le-opioid ukuze lingasebenzi okanye kunokubangela iimpawu zokurhoxa.
Sebenzisa i-benzodiazepines okanye ezinye i-CNS depressants (kubandakanya amanye amayeza e-opioid) ngokudibeneyo ne-hydrocodone okanye i-oxycodone kunokukhokelela kwi-hypotension, uxinzelelo lokuphefumla, i-sedation enzulu, ikhoma kunye nokufa.
Ukuthatha i-hydrocodone okanye i-oxycodone ngamachiza anyusa i-serotonin kunokwandisa umngcipheko we-serotonin syndrome. La machiza abandakanya i-SSRI kunye ne-SNRI anti-depressants, tricyclic antidepressants, relaxant muscle, MAO inhibitors (MAO inhibitors akufuneki zisetyenziswe kwiintsuku ezili-14 ze-hydrocodone okanye i-oxycodone), kunye ne-triptans ye-migraine. Nxibelelana nomboneleli wakho wezempilo uluhlu olupheleleyo lokudibana kwamachiza.
| Iziyobisi | Iklasi yeziyobisi | IHydrocodone | Oxycodone |
| Erythromycin Biaxin (icleithromycin) | I-Macrolide antibiotics | Ewe | Ewe |
| I-Diflucan (i-fluconazole) Nizoral (ketoconazole) | I-Azole yokubola | Ewe | Ewe |
| INorvir (ritonavir) | Iprotease inhibitors | Ewe | Ewe |
| Rifampin Tegretol (icarbamazepine) Idilantin (phenytoin) | I-CYP3A4 inducers | Ewe | Ewe |
| Xanax (alprazolam) Valium (diazepam) Ativan (ilorazepam) IKlonopin (clonazepam) | IiBenzodiazepines | Ewe | Ewe |
| Imethadone UTylenol kunye nekhowudi (APAP / ikhowudi) Ukuhlala ixesha elide (fentanyl) Imofini Naziphi na ezinye iindlela zehydrocodone okanye ioxycodone | Iipioids | Ewe | Ewe |
| Utywala | Utywala | Ewe | Ewe |
| IFlexeril (cyclobenzaprine) I-Skelaxin (metaxalone) | Ukuphumla kwezihlunu | Ewe | Ewe |
| Imitrex (is sumatriptan) IMaxalt (irizatriptan) | IiTriptans | Ewe | Ewe |
| Iprozac (fluoxetine) I-Paxil (iparoxetine) Zoloft (sertraline) UCelexa (citalopram) ILexapro (esitalitalopram) | I-SSRI yoxinzelelo | Ewe | Ewe |
| I-Pamelor (inortriptyline) I-Elavil (amitriptyline) | I-Tricyclic yoxinzelelo | Ewe | Ewe |
| ICymbalta (duloxetine) I-Effexor (venlafaxine) IPristiq (desvenlafaxine) | I-SNRI yoxinzelelo | Ewe | Ewe |
| IHydrochlorothiazide I-Lasix (furosemide) | Womchamo | Ewe | Ewe |
| I-Azilect (rasagiline) I-Eldepryl (selegiline) Iparnate (itranylcypromine) | I-MAO inhibitors | Ewe | Ewe |
| Cogentin (benztropine) IBenadryl (diphenhydramine) I-Ditropan (i-oxybutynin) Ukujonga (itolterodine) | Iziyobisi zeAnticholinergic | Ewe | Ewe |
Izilumkiso zehydrocodone kunye ne-oxycodone
Kukho isilumkiso sebhokisi kwi-hydrocodone kunye ne-oxycodone, esisilumkiso esomeleleyo esifunwa yi-FDA. Ezinye izilumkiso zibandakanya:
- Iiopioids zinomngcipheko wokuba likhoboka, ukuxhatshazwa, kunye nokusetyenziswa gwenxa, ezinokuthi zikhokelele ekugqithiseni nasekufeni. Izigulana kufuneka zivavanywe umngcipheko ngaphambi kokuthatha i-opioid kwaye kufuneka zibekwe esweni rhoqo.
- Ukuqinisekisa ukuba izibonelelo ze-opioids zingaphezulu komngcipheko wokuba likhoboka leziyobisi, ukusetyenziswa gwenxa kweziyobisi kunye nokusetyenziswa gwenxa, iinkampani zeziyobisi kufuneka zifundise ababoneleli ngezempilo. Ababoneleli ngezempilo kufuneka bazalise i-REMS (Inkqubo yokuVavanya okusemngciphekweni kunye neNkqubo yokuNciphisa), inkqubo yokuhambelana nemfundo, ukucebisa abaguli kunye nabanonopheli ngonyango ngalunye, kwaye ugxininise ukubaluleka kokufunda isikhokelo sonyango, esinikwa iphepha ngalinye.
- I-Opioids inokubangela ukoyikisa, ukusongela ubomi, okanye uxinzelelo lokuphefumla. Izigulana kufuneka zijongwe, ngakumbi ekuqaleni konyango kunye nokulandela utshintsho kumthamo.
- Ukungena ngengozi, ngakumbi ngabantwana, kunokubangela ukugqithisa okubulalayo. Izigulana kufuneka zifundiswe ukuba zikhusele ii-opioid ngaphandle kwabantwana.
- Isifo sokurhoxiswa kwe-opioid ye-neonatal kunokubangela ukusetyenziswa kwe-opioid ixesha elide ngexesha lokukhulelwa kwaye kunokuba sesichengeni sobomi ukuba ayaziwa kwaye inyangwa.
- Sebenzisa ii-opioids ezinamayeza athile atyetyiswa yi-enzyme cytochrome P 450 3A4 inokunyusa amanqanaba e-opioid kwaye ibangele ukwanda kweziphumo ebezingalindelekanga ezinokubangela ukudakumba okuphefumlayo.
- Sebenzisa iziyobisi ze-benzodiazepine ezinje ngeXanax (alprazolam), Valium (diazepam), okanye ezinye izinto zokudakumba ze-CNS, ezinje ngezinye iiopioid (okanye utywala), kunokubangela ukudakumba okunzulu, uxinzelelo lokuphefumla, ikhoma kunye nokufa, kwaye kufanele kuthintelwe ukuba kunokwenzeka. Izigulana ezithatha olu dibaniso ngenxa yezinye iindlela ezingasebenziyo kufuneka zijongwe ngeliso elibukhali.
Ezinye izilumkiso kunye nezimo zibandakanya:
- I-Hydrocodone okanye i-oxycodone akufuneki isetyenziswe kwizigulana ezinesifo sokuphefumla, isifo sesifuba esibuhlungu okanye esibukhali kwisimo esingabekelw 'esweni, isithintelo samathumbu, okanye i-hypersensitivity kuso nasiphi na isithako.
- I-Hydrocodone okanye i-oxycodone akufuneki isetyenziswe kwizigulana ezinesifo esinganyangekiyo semiphunga okanye abagulayo okanye abagulayo.
- Ukungoneli kwe-adrenal kunokwenzeka, ngesiqhelo emva kwenyanga enye. Funa unyango ukuba kukho naziphi na kwezi mpawu zenzekayo: isicaphucaphu, ukugabha, ianorexia, ukudinwa, ukuba buthathaka, isiyezi, kunye noxinzelelo lwegazi.
- I-Hydrocodone okanye i-oxycodone inokubangela uxinzelelo lwegazi oluphantsi.
- Sukusebenzisa i-hydrocodone okanye i-oxycodone kwizigulana ezinengxaki yokuziva kakuhle okanye ezikwi-coma.
- I-Hydrocodone okanye i-oxycodone inokunyusa umngcipheko wokubanjwa kwizigulana ezinengxaki yokuthimba.
- I-Hydrocodone okanye i-oxycodone akufuneki irhoxiswe ngesiquphe kodwa kufuneka icofwe kancinci.
- Musa ukuqhuba okanye ukusebenzisa oomatshini de ube uyazi indlela elikuchaphazela ngayo iyeza.
- Iiopioid ezingakhuselekanga zinokuba yingozi komnye umntu ekhaya, kubandakanya neendwendwe. Gcina ngokukhuselekileyo, ngaphandle kwembonakalo kunye nokufikelela kwabantwana, nakwindawo engafikelelekiyo kwabanye. Buza kwingcali yakho ukuba ungazilahla njani ii-opioid ezingasetyenziswanga kwindawo yakho.
Kuba akukho zifundo zilawulwa kakuhle kwabasetyhini, i-hydrocodone okanye i-oxycodone akufuneki isetyenziswe xa ukhulelwe ngaphandle kokuba izibonelelo zingaphezulu kobungozi. Ukusetyenziswa ixesha elide kweeopioid ngexesha lokukhulelwa, nokuba kusetyenziselwa unyango okanye kungasetyenziswa kunyango, kunokubangela ukuxhomekeka emzimbeni wosana, okukhokelela kwisifo sokurhoxa kwe-opioid ye-neonatal kungekudala emva kokuzalwa.
Izilumkiso ezithile kwi-acetaminophen (APAP) ehlala ifunyenwe ngokudibeneyo nehydrocodone okanye i-oxycodone zezi:
- I-Acetaminophen inokubangela ulusu olunobuzaza njenge-pustulosis (AGEP), iStevens-Johnson Syndrome (SJS), kunye ne-epidermal necrolysis (TEN) enokubulala. Izigulana kufuneka zifune unyango olukhawulezileyo ukuba kwenzeka ulusu.
- Kukho umngcipheko wokungaphumeleli kwesibindi ngenxa ye-APAP. Ugqirha wakho kufuneka akuxelele ubuninzi bemihla ngemihla ye-APAP ongayithatha, kwaye kufuneka ujonge amanye amayeza owathathayo kwi-APAP (njenge-NyQuil).
- Hypersensitivity okanye anaphylaxis inokwenzeka. Funa unyango olungxamisekileyo ukuba ngaba kukho enye yezi mpawu kunye neempawu ezenzekayo: ukudumba kobuso, umlomo, nomqala, uxinzelelo lokuphefumla, urticaria, irhashalala, ipruritus kunye nokugabha.
Imibuzo ebuzwa rhoqo malunga ne-hydrocodone vs i-oxycodone
Yintoni ihydrocodone?
I-Hydrocodone yipainiller ye-opioid esetyenziselwa ukunyanga iintlungu ezingaphenduliyo kwiintlungu ezinamandla. Itholakala ngeendlela ezahlukeneyo, ngokuqhelekileyo kunye ne-acetaminophen ngendlela yeNorco.
Yintoni ioxycodone?
I-Oxycodone sisixhobo sokudambisa iintlungu esisetyenziselwa ukunyanga iintlungu ezingaphenduliyo kwiipilisi zentlungu. Iyafumaneka ngeendlela ezahlukeneyo, ihlala iyodwa (kuzo zombini iifom zokukhululwa kwangoko kunye nezokukhutshwa) kunye ne-acetaminophen ngohlobo lwePercocet.
Ngaba i-hydrocodone kunye ne-oxycodone ziyafana?
Omabini la machiza anamandla okwehlisa iintlungu. Ngelixa zifana kakhulu, zinomahluko othile, njengakwidosi, echazwe apha ngasentla.
Ngaba i-hydrocodone okanye i-oxycodone ingcono?
Kwizifundo, zombini iziyobisi zibonise ukubonelela ngeentlungu ezisebenzayo. Nangona kunjalo, omabini la machiza omelele kakhulu kwaye anamandla aphezulu okuphathwa gadalala. Qhagamshelana nomboneleli wakho wezempilo malunga neengcebiso ezenzelwe wena.
Ndingayisebenzisa i-hydrocodone okanye i-oxycodone ngelixa ndikhulelwe?
Akufanele usebenzise i-hydrocodone okanye i-oxycodone ngelixa ukhulelwe ngaphandle kokuba ugqirha wakho ugqiba ukuba isibonelelo kuwe sigqitha umngcipheko kwimveku engekazalwa. Kwakhona, ukusebenzisa ii-opioid ixesha elide ngexesha lokukhulelwa kunokubangela ukuxhomekeka kwimveku, kwaye kunokukhokelela kwisifo sokurhoxa kwe-opioid ye-neonatal.
Ndingayisebenzisa i-hydrocodone okanye i-oxycodone ngotywala?
Hayi. I-Hydrocodone okanye i-oxycodone akufuneki isetyenziswe notywala. Umdibaniso ungakhokelela ekuthambekeni okunzulu, uxinzelelo lokuphefumla, isiqaqa, okanye ukufa.
Ungathatha i-hydrocodone kunye ne-oxycodone kunye?
Hayi. I-Hydrocodone kunye ne-oxycodone akufuneki zisetyenziswe kunye. Indibaniselwano inokuba yingozi kakhulu kwaye ikhokelele kuxinzelelo lokuphefumla okanye ukufa. Esi sesinye sezizathu zokuba kubaluleke kakhulu ukulahla ii-opioid ezindala xa zingasafuneki. Buza usokhemesti wakho ukuba angalahla njani amayeza kwindawo ekufuphi kuwe.
Kutheni le nto abanye abantu besebenzisa ihydrocodone kwiziphumo zokuzonwabisa?
Ngelixa ukunciphisa iintlungu, ii-opioids ezinje ngehydrocodone okanye i-oxycodone zinokuvelisa ukusebenza euphoric . Iiopioids zinokubakho okuphezulu ekusebenziseni iziyobisi gwenxa. Xa uthatha iyeza le-opioid, sebenzisa kuphela njengoko kumiselwe. Musa ukuthatha amanani angaphezulu, kwaye ungadibanisi notywala. Buza ugqirha wakho okanye usokhemesti malunga nokunxibelelana kweziyobisi. Lahla iyeza xa ungaselifuni; sukuyigcina ngelinye ixesha. Inokuba yingozi kuye nakubani na ekhaya.
