Eyona >> Iziyobisi Vs. Umhlobo >> I-Metoprolol tartrate vs metoprolol succinate: Umahluko, ukufana, kwaye kukuphi okungcono kuwe

I-Metoprolol tartrate vs metoprolol succinate: Umahluko, ukufana, kwaye kukuphi okungcono kuwe

Iziyobisi Vs. Umhlobo

Ukuba ukhe wahlaselwa sisifo sentliziyo okanye ngoku uhlala noxinzelelo lwegazi, ugqirha wakho unokukunika ichiza elinje nge-metoprolol tartrate (Lopressor) okanye metoprolol succinate (Toprol XL). Nangona omabini la machiza enezithako ezifanayo ezisebenzayo, anokusetyenziswa ngeendlela ezahlukeneyo.

Zombini i-metoprolol tartrate kunye ne-metoprolol succinate zezodidi lweziyobisi ezibizwa iibhloko ze-beta . Ngamanye amaxesha baziwa njenge-beta-1 ekhethiweyo ye-adrenoceptor blockers kunye ne-beta antagonists.

La machiza asebenza ngokuthintela iziphumo zehomoni ezinje nge-epinephrine kunye ne-norepinephrine kwinkqubo yovelwano yemfesane. Inkqubo yemfesane yovelwano inoxanduva lokuphendula okulwa-okanye-ukubhabha. I-Metoprolol inokunceda ukunciphisa uxinzelelo entliziyweni, ukhulule imithambo yegazi ukunciphisa uxinzelelo lwegazi, kunye nokunciphisa iintlungu zesifuba.

Yintoni umahluko ophambili phakathi kwe-metoprolol tartrate kunye ne-metoprolol succinate?

Umahluko ophambili phakathi kwe-metoprolol tartrate (Yintoni i-metoprolol tartrate?) Kunye ne-metoprolol succinate (Yintoni i-metoprolol succinate?) Ikwimo yazo. I-Metoprolol tartrate yinguqulelo ekhutshwa kwangoko ye-metoprolol ngelixa i-metoprolol succinate yinguqulelo eyandisiweyo. Oku kuthetha ukuba i-metoprolol succinate ikhutshwa ngokuhamba kwexesha emzimbeni ekhokelela kwiziphumo ezisebenza ixesha elide.

I-Metoprolol tartrate inokufuna ukuthathwa amaxesha ngamaxesha ngemini. I-Metoprolol succinate inokuthathwa kube kanye yonke imihla kuba ihlala ixesha elide kunefom ye-tartrate. I-Metoprolol succinate inokusetyenziswa nakubantwana abaneminyaka eyi-6 nangaphezulu ngelixa i-metoprolol tartrate inokusetyenziswa kuphela kubantu abadala.

Umahluko ophambili phakathi kwe-metoprolol tartrate kunye ne-metoprolol succinate
	Imetoprolol iTartrate	IMetoprolol Succinate
Iklasi yeziyobisi	Ibhloko blocker	Ibhloko blocker
Uhlobo lweBrith / generic	Ibhranti kunye nohlobo oluqhelekileyo olukhoyo	Ibhranti kunye nohlobo oluqhelekileyo olukhoyo
Ngubani igama lophawu?	Lopressor	Itrolol XL
Zeziphi iifom eza nalo iziyobisi?	Ithebhulethi yomlomo	Ithebhulethi yomlomo, ukukhutshwa okwandisiweyo
Ithini idosi esemgangathweni?	I-100 mg ukuya kwi-400 mg yonke imihla ngeedosi ezahluliweyo	100 mg kanye yonke imihla
Lude kangakanani unyango oluqhelekileyo?	Ixesha elifutshane okanye ukusetyenziswa kwexesha elide njengoko kuyalelwe ngugqirha	Ixesha elifutshane okanye ukusetyenziswa kwexesha elide njengoko kuyalelwe ngugqirha
Ngubani oqhelekileyo usebenzisa amayeza?	Abantu abadala	Abantu abadala nabantwana abaneminyaka eyi-6 nangaphezulu

Ngaba ufuna elona xabiso lilungileyo kwimetoprolol tartrate?

Bhalisela izilumkiso zamaxabiso e-metoprolol tartrate kwaye ufumane ukuba amaxabiso atshintsha nini!

Fumana izilumkiso zamaxabiso

Iimeko eziphathwe nge-metoprolol tartrate kunye ne-metoprolol succinate

Iifomati zetartrate kunye ne-succinate ze-metoprolol zivunyiwe yi-FDA ukunyanga uxinzelelo lwegazi (uxinzelelo lwegazi) kunye nentlungu yesifuba (angina pectoris).

I-Metoprolol tartrate ikwamkelwe njenge-FDA njengonyango kanye emva kwe ukuhlaselwa yintliziyo (isifo sephepha esibukhali). Ukuthatha i-metoprolol tartrate emva kokuhlaselwa kwentliziyo kunokunceda ukunciphisa umngcipheko wokuqhubeka kweziganeko zentliziyo kunye nokufa ngakumbi kwabo bane-coronary artery disease. Unyango kufuneka luqale kwiintsuku ezi-3 ukuya kwezi-10 emva kokuhlaselwa kwentliziyo.

Ukongeza uxinzelelo lwegazi oluphezulu kunye nentlungu yesifuba, i-metoprolol succinate ikwayi-FDA-evunyiweyo ukunyanga ukungaphumeleli kwentliziyo . Ngokukodwa, i-metoprolol succinate inyanga ukusilela kwentliziyo okungapheliyo oko kukuthi Umbutho wentliziyo waseNew York iklasi II okanye III. Ukunikezelwa njengedosi yemihla ngemihla, i-metoprolol succinate inokuphucula iziphumo kunye nokunciphisa umngcipheko wokufa kwizigulana ezingaphumeleli kwintliziyo.

Ngaphandle kwelebheli Ukusetyenziswa kwe-metoprolol kubandakanya i-tachycardia engaphezulu (inqanaba lentliziyo elikhawulezileyo) kunye nesiphepho se-thyroid (imeko eyingozi ebangelwa kukuveliswa kakhulu kwehomoni yedlala lengqula). Olunye usetyenziso lweelebheli ezingafunekiyo lunokubandakanya unyango lwesingqisho sentliziyo esingaqhelekanga (arrhythmia) kunye uxinzelelo lokusebenza .

Imeko	Imetoprolol iTartrate	IMetoprolol Succinate
Igazi elonyukayo	Ewe	Ewe
Intlungu engapheliyo yesifuba	Ewe	Ewe
Ukuhlaselwa yintliziyo	Ewe	Ngaphandle kwelebheli
Ukumelwa yintliziyo	Ngaphandle kwelebheli	Ewe
I-Supraventricular tachycardia	Ngaphandle kwelebheli	Ngaphandle kwelebheli
Uqhwithela	Ngaphandle kwelebheli	Ngaphandle kwelebheli
Arrhythmia	Ngaphandle kwelebheli	Ngaphandle kwelebheli
Ukuxhalaba kokusebenza	Ngaphandle kwelebheli	Ngaphandle kwelebheli

Ngaba i-metoprolol tartrate okanye i-metoprolol iyasebenza ngakumbi?

I-Metoprolol tartrate kunye ne-metoprolol succinate zombini ziyafana ngokusebenza kunyango lwegazi oluphezulu kunye nentlungu engapheliyo yesifuba. Nangona kunjalo, i-metoprolol tartrate inokusebenza ngakumbi njengonyango lokuhlaselwa sisifo sentliziyo ngelixa i-metoprolol succinate inokusebenza ngakumbi njengonyango lokungaphumeleli kwentliziyo.

Zonyango izilingo Ndibonisile ukuba i-metoprolol tartrate iyasebenza kuxinzelelo lwegazi kunye nokuthintela iziphumo ezibi emva kokuhlaselwa sisifo sentliziyo. Ngokuchasene noko, izifundo ezibandakanya ulingo lwe-Merit-HF zibonisile ukuba i-metoprolol succinate ingaphezulu kune-metoprolol tartrate yokusilela kwentliziyo okungapheliyo.

I-Metoprolol succinate inokunciphisa ukutyelelwa rhoqo esibhedlele kunye nokufa ngenxa yokusilela kwentliziyo. Nangona kunjalo, umfanekiso oqingqiweyo , enye into ekuthiwa yi-beta blocker eqhelekileyo, inokusebenza ngakumbi kune-metoprolol succinate, ngokwetyala elipapashwe kwifayile ye- ILancet .

Ngenxa yokuba i-metoprolol tartrate ithathwa amaxesha ngamaxesha emini, amanqanaba eziyobisi emzimbeni isenokungalingani. Oku kunokubangela iziphumo ebezingalindelekanga ngakumbi kunye nokunyamezeleka okuncinci xa kuthelekiswa nefom ye-succinate ekhutshiweyo. Nye Uhlalutyo ifumanise ukuba iziphumo ebezingalindelekanga ezinje ngokubetha kwentliziyo kancinci (i-bradycardia) kunokuba nakho ukubakho xa kukhutshwa i-metoprolol tartrate kwangoko.

Umyinge kunye neendleko zokuthelekisa i-metoprolol tartrate vs metoprolol succinate

I-Metoprolol tartrate inokuthengwa njengechiza likagqirha eliqhelekileyo elihlala ligutyungelwe yiMedicare kunye nezinye izicwangciso zeinshurensi. Ngaphandle kweinshurensi, ixabiso eliphakathi lemali le-metoprolol tartrate lijikeleze i- $ 5. Amakhadi esaphulelo se-singleCare anokusetyenziswa kwiikhemesti ezithatha inxaxheba ukunciphisa iindleko zeli chiza. Unokufumana ixabiso elikufutshane ne- $ 4 kunye nekhuphoni lokugcina.

I-Metoprolol succinate okanye i-metoprolol ekhutshiweyo ekhutshiweyo iyafumaneka njengamayeza enziwe afana nalawo enziwa ngumenzi agutyungelwe luninzi lwezonyango kunye nezicwangciso zeinshurensi. I-generic metoprolol succinate kunokwenzeka ukuba igqunywe kunegama lophawu lweToprol XL. Ixabiso eliphakathi lokuthengisa i-Toprol XL ejikeleze iidola ezingama-56. Jonga ikhemesti yakho ukuze ubone ukuba ungagcina ngaphezulu ngekhadi lokugcina i-SingleCare. Ukuba yamkelwe, unganciphisa iindleko ukuya kwi- $ 9

	Imetoprolol iTartrate	IMetoprolol Succinate
Ngokuqhelekileyo ihlawulwa yi-inshurensi?	Ewe	Ewe
Ngokuqhelekileyo igutyungelwe yiMedicare?	Ewe	Ewe
Umthamo osemgangathweni	Iipilisi ezingama-50 mg	Iipilisi ze-100 mg
I-Medicare copay eqhelekileyo	$ 0- $ 65	$ 0- $ 20
Ixabiso elilodwa	$ 4	$ 9

Fumana ikhadi lesaphulelo kwikhemesti

Iziphumo eziqhelekileyo ezichaphazelekayo ze-metoprolol tartrate vs metoprolol succinate

I-Metoprolol tartrate kunye ne-metoprolol succinate inokubangela iziphumo ezifanayo. Iziphumo zixhaphakileyo ze-metoprolol zibandakanya ukudinwa okanye ukudinwa, isiyezi, ukudakumba, ukuphefumla kancinci (i-dyspnea), kunye nokubetha kwentliziyo kancinci (i-bradycardia). Ezinye iziphumo ebezingalindelekanga zibandakanya urhudo, isicaphucaphu, ukugabha kunye nomlomo owomileyo.

Impendulo ye-Hypersensitivity efana nokukhawuleza okanye ukurhawuzelela kunokwenzeka xa uthatha nayiphi na indlela ye-metoprolol. Ngokusekwe kwi- Ileta ye-FDA I-metoprolol tartrate inokubangela iziphumo ebezingalindelekanga ezithile.

	Imetoprolol iTartrate	IMetoprolol Succinate
Imiphumela	Iyasebenza?	Rhoqo	Iyasebenza?	Rhoqo
Ukudinwa	Ewe	10%	Ewe	> 2%
Ukuba nesiyezi	Ewe	10%	Ewe	> 2%
Irhashalala	Ewe	5%	Ewe	> 2%
Uxinzelelo	Ewe	5%	Ewe	> 2%
Urhudo	Ewe	5%	Ewe	> 2%
Ukuqhawukelwa ngumphefumlo	Ewe	3%	Ewe	> 2%
Ukubetha kwentliziyo kancinci	Ewe	3%	Ewe	> 2%
Umlomo owomileyo	Ewe	1%	Ewe	* akuxelwa
Isicaphucaphu	Ewe	1%	Ewe	*
Isitshisa	Ewe	1%	Ewe	*
Ukuqunjelwa	Ewe	1%	Ewe	*

Olu alunakuba luluhlu olupheleleyo. Dibana nogqirha wakho okanye usokhemesti ngeziphumo ebezingalindelekanga ezinokubakho.

Umthombo: Mihla le (iMetoprolol tartrate) , I-DailyMed (i-metoprolol succinate)

Ukudibana kweziyobisi kwe-metoprolol tartrate vs metoprolol succinate

I-Metoprolol tartrate kunye ne-metoprolol succinate inokusebenzisana namayeza afanayo. Amanye amachiza anezenzo ezifanayo okanye achaphazela imetabolism ye-beta blockers anokusebenzisana nazo zombini iindlela ze-metoprolol.

I-Metoprolol akufuneki ithathwe ngamachiza okuphelisa i-catecholamine. Ukuthatha la mayeza kunye kunganyusa ifuthe le-beta blockers kwaye kubangele izehlo ezimbi ezinje ngexinzelelo lwegazi ( hypotension ) kunye nokubetha kwentliziyo kancinci (bradycardia). Ezinye iziphumo ezibi zinokubandakanya ukuba nesiyezi kunye nokuphelelwa ngamandla.

I-Metoprolol icutshungulwa kakhulu yi-CYP2D6 enzyme. Ke ngoko, iziyobisi ezithintela le enzyme zinokubangela ukwanda kwamanqanaba e-metoprolol emzimbeni. Ukunyuka kwamanqanaba e-metoprolol kunokunyusa umngcipheko weziphumo ezibi.

I-Digoxin kunye neziyobisi ezibizwa ngokuba yi-calcium channel blockers zinokuba neziphumo ezongeziweyo xa zinikwa nge-metoprolol. Ukuthatha naliphi na kula machiza nge-metoprolol kunokubangela iziphumo ebezingalindelekanga entliziyweni.

Iziyobisi	Iklasi yeziyobisi	Imetoprolol iTartrate	IMetoprolol Succinate
Hlaziya ngokutsha Tetrabenazine	Ukusetyenziswa kweziyobisi kweCatecholamine	Ewe	Ewe
Iquinidine IFluoxetine IFluvoxamine Sertraline IBupropion Paroxetine Ipropafenone IHaloperidol Idiphenhydramine IHydroxychloroquine I-Terbinafine	CYP2D6 inhibitor	Ewe	Ewe
I-Digoxin	Iglycoside yentliziyo	Ewe	Ewe
Diltiazem I-Verapamil	Isikhululo seCalcium blocker	Ewe	Ewe
Clonidine IGuanethidine I-Betanidine	IAlfa-adrenergic arhente	Ewe	Ewe

Olu alunakuba luluhlu olupheleleyo lwazo zonke izinto ezinokubakho xa kusenziwa iziyobisi. Dibana nogqirha nawo onke amayeza onokuthi uwathathe.

Izilumkiso ze-metoprolol tartrate kunye ne-metoprolol succinate

Zombini i-metoprolol tartrate kunye ne-metoprolol succinate akufuneki ziyekwe ngesiquphe. Ukuba unyango nge-metoprolol lumiswe ngesiquphe, abanye abantu banokufumana umngcipheko ophezulu wokuhlaselwa sisifo sentliziyo, engaqhelekanga isingqisho sentliziyo , nentlungu esifubeni. Umngcipheko wezi ziganeko uphezulu kwabo banezifo zentliziyo ezingaphantsi.

Iibhloko blocker njenge-metoprolol akufuneki zisetyenziswe nakubani na wale miqathango ilandelayo:

I-bradycardia enzima
Intliziyo ibhloko enkulu kunedigri yokuqala
Umothuko weCardiogenic
Ukusilela kwentliziyo ukubola
Isifo sesinus esigula ngaphandle kwesincedisi-ntliziyo
Hypersensitivity kuzo naziphi na izithako kula machiza

Dibana nogqirha wakho ukuze ubone ukuba unganazo na ezi meko phambi kokuba uqale unyango.

Iibhlokhi zeBeta zinokufihla imiqondiso kunye neempawu zehypoglycemia, okanye iswekile esezantsi yegazi. Abo banesifo seswekile banokufuna ukubeka esweni iswekile yegazi labo ngelixa bethatha iibhlokhi ze-beta.

Imibuzo ebuzwa rhoqo malunga ne-metoprolol tartrate vs metoprolol succinate

Yintoni i-metoprolol tartrate?

I-Metoprolol tartrate ligama eliqhelekileyo leLopressor. I-beta blocker esetyenziselwa ukunyanga uxinzelelo lwegazi oluphezulu kunye nentlungu engapheliyo yesifuba. Kukwamkelwe ukuba kunyangwe isifo sentliziyo esibuhlungu ukunciphisa umngcipheko wokufa.

Yintoni i-metoprolol succinate?

I-Metoprolol succinate yaziwa ngokuba ligama lophawu iToprol XL. Yifomu ekhululweyo yokukhululwa kwe-metoprolol. I-Metoprolol succinate yamkelwe ukunyanga uxinzelelo lwegazi oluphezulu, iintlungu zesifuba esinganyangekiyo kunye nokuxinana ukumelwa yintliziyo .

Ngaba i-metoprolol tartrate kunye ne-metoprolol zisebenza ngendlela efanayo?

Hayi.I-Metoprolol tartrate yithebhulethi ekhupha kwangoko ngelixa i-metoprolol succinate yithebhulethi ekhulisiweyo. Zingasetyenziswa ngeendlela ezahlukeneyo.

Ngaba i-metoprolol tartrate okanye i-metoprolol iyancipha ngcono?

I-Metoprolol tartrate kunye ne-metoprolol succinate zombini ziyasebenza ngokuxhomekeke kwimeko yokunyangwa. I-Metoprolol succinate iyasebenza ngakumbi ekunyangeni ukusilela kwentliziyo. I-Metoprolol succinate isenokungabikho amathuba okubangela iziphumo ebezingalindelekanga.

Ndingayisebenzisa i-metoprolol tartrate okanye i-metoprolol succinate ngelixa ukhulelwe?

I-Metoprolol kufuneka isetyenziswe kuphela ngexesha lokukhulelwa ukuba izibonelelo ngokucacileyo zingaphezulu komngcipheko. Akukho zifundo zaneleyo zenziweyo zibonisa ukuba la mayeza akhuselekile kwi-100% ngexesha lokukhulelwa. Dibana nogqirha ukuba ukhulelwe okanye uncelisa.

Ndingayisebenzisa i-metoprolol tartrate okanye i-metoprolol succinate ngotywala?

Ukusela utywala ngelixa uthatha i-metoprolol kunokunyusa umngcipheko wozela kunye nesiyezi. Akukhuthazwa ngokubanzi ukusebenzisa i-metoprolol kunye utywala .

Ngaba ungatshintsha ukusuka kwi-metoprolol tartrate ukuya kwiscucate?

Ngamanye amaxesha, i-metoprolol tartrate inokutshintshelwa kwi-metoprolol succinate. I-Metoprolol succinate inokukhethwa kwi-dosing yayo yemihla ngemihla. Nxibelelana nogqirha ukuze ufumane unyango lwakho xa utshintsha amayeza.

Kufuneka ungayithathi nini i-metoprolol?

I-Metoprolol akufuneki ithathwe ukuba unamaqondo asezantsi kakhulu kwentliziyo, uxinzelelo lwegazi, okanye ukusilela kwentliziyo. Kubalulekile ukuxoxa ngembali yakho yezonyango nogqirha ukumisela ukuba kufanele ukuba ukwimetoprolol.

Yintoni ekufuneka ndiyiphephe ngelixa ndithatha i-metoprolol?

Utywala kunye namayeza athile kufuneka athintelwe ngelixa uthatha i-metoprolol. Amanye amayeza kubandakanya i-calcium channel blockers, ngokuqinisekileyo iziyobisi , kunye nezo ziqhutywa ngendlela efanayo ne-metoprolol inokunyusa umngcipheko weziphumo ezibi nge-metoprolol.

Ngaba i-metoprolol yonyango olunomngcipheko ophezulu?

Ewe. I-Metoprolol inokuthathwa njengeyeza elinomngcipheko omkhulu. Xa isetyenziswe ngendlela engafanelekanga, i-metoprolol inokubangela ingozi enkulu.