ISymbicort vs.Advair: Umahluko, ukufana, kwaye kukuphi okungcono kuwe
Iziyobisi Vs. UmhloboUkujonga ngokubanzi iziyobisi kunye nolwahluko ophambili | Imiqathango iphathwe | Ukusebenza | Ukuhlawulwa kwe-inshurensi kunye nokuthelekiswa kweendleko | Imiphumela | Ukusebenzisana kweziyobisi | Izilumkiso | FAQ
I-Symbicort kunye ne-Advair ngamayeza amabini anegama kraca asetyenziselwa ukunyanga isifuba kunye nesifo esinganyangekiyo semiphunga (COPD). Isifuba kunye neCOPD ziimeko ezichaphazela imiphunga kwaye zibangele ukudumba kwiindlela zomoya. Iimpawu ze-asthma kunye ne-COPD zibandakanya ukuphefumla okunzima, ukuvutha kunye nokukhohlela.
I-Symbicort kunye ne-Advair zizilondolozi ze-inhalers ezidibanisa i-corticosteroid ye-inhaled (ICS) kunye ne-beta agonist esebenza ixesha elide (LABA). Ezi inhalers zisetyenziswa yonke imihla ukunceda ukulawula ukudumba emiphungeni kunye nokugcina umoya uvulekile. Azisetyenziswanga njenge-inhalers yokuhlangula kwiimpawu ezibukhali zesifuba okanye i-COPD. Ngaphandle kokufana kwazo, iSymbicort kunye neAdvair zinomahluko okhoyo kwizithako ezisebenzayo kunye nomthamo ocetyiswayo.
Yintoni umahluko ophambili phakathi kweSymbicort kunye neAdvair?
I-Symbicort kunye ne-Advair ziqulathe i-corticosteroid, enefuthe lokuchasana nemiphunga. I-Symbicort iqulethe i-corticosteroid budesonide ngelixa iAdvair ine-corticosteroid fluticasone. ISymbicort kunye neAdvair zikwanesixhobo se-bronchodilator esisebenza ixesha elide, esinceda ukugcina iindlela zomoya zivulekile; I-Symbicort iqulethe i-formoterol ngelixa i-Advair iqulethe i-salmeterol.
I-Symbicort isetyenziswa njengonyango lokugcina i-COPD, kwaye inokusetyenziselwa ukunyanga isifo sombefu kubantu abaneminyaka emi-6 nangaphezulu. I-Advair ikwasetyenziswa njengonyango lokugcina i-COPD, kwaye inokusetyenziselwa ukunyanga isifuba kubantu abaneminyaka emi-4 nangaphezulu. Umthamo oqhelekileyo weSymbicort kukufuthaniseleka kabini kabini imihla ngemihla ngelixa idosi yesiqhelo yeAdvair yenye inhalation kabini yonke imihla.
I-Symbicort iza njenge-inhalation aerosol enamandla angama-80 / 4.5 mcg okanye i-160 / 4.5 mcg ye-budesonide / formoterol. I-Advair ifumaneka njenge-inhalation aerosol kunye ne-inhalation powder, kodwa i-inhalation aerosol yamkelwe kuphela ukunyanga isifuba ngelixa i-inhalation powder inokunyanga isifuba kunye ne-COPD. I-Advair HFA yidosi ye-ineredr yedosi ehambisa i-inhalation aerosol kumandla e-45/21 mcg, 115/21 mcg, okanye i-230/21 mcg ye-fluticasone / salmeterol. I-Advair Diskus ihambisa umgubo we-inhalation ngamandla e-100/50 mcg, 250/50 mcg, okanye 500/50 mcg ye-fluticasone / salmeterol.
| Umahluko ophambili phakathi kweSymbicort kunye neAdvair | ||
|---|---|---|
| Uphawu | Idilesi | |
| Iklasi yeziyobisi | I-ICS (inhaled corticosteroid) kunye neLABA (esebenza ixesha elide i-beta2-adrenergic agonist) | I-ICS (inhaled corticosteroid) kunye neLABA (esebenza ixesha elide i-beta2-adrenergic agonist) |
| Uhlobo lweBrith / generic | Ibhranti kunye nohlobo oluqhelekileyo olukhoyo | Ibhranti kunye nohlobo oluqhelekileyo olukhoyo |
| Ngubani igama eliqhelekileyo? | I-Budesonide kunye ne-formoterol fumarate dihydrate | Fluticasone propionate kunye salmeterol |
| Zeziphi iifom eza nalo iziyobisi? | Inhalation i-aerosol (i-ineredr-dose inhaler) | Inhalation i-aerosol (i-ineredr-dose inhaler) Inhalation powder (i-diskus) |
| Ithini idosi esemgangathweni? | Unyango lwe-asthma kwizigulana ezineminyaka eyi-12 nangaphezulu: Inhalations ezi-2 zeSymbicort 80 / 4.5 okanye 160 / 4.5 kabini yonke imihla Unyango lwe-asthma kwizigulana ezineminyaka emi-6 ubudala ukuya kuthi ga ngaphantsi kweminyaka eyi-12: Inhalations ezi-2 zeSymbicort 80 / 4.5 kabini yonke imihla Unyango lolondolozo lweCOPD: Inhalations ezi-2 zeSymbicort 160 / 4.5 kabini yonke imihla | Advair Diskus Unyango lwe-asthma kwizigulana ezineminyaka eyi-12 nangaphezulu: Inhalation e-1 ye-Advair Diskus 100/50, 250/50, okanye 500/50 kabini yonke imihla Unyango lwe-asthma kwizigulana ezineminyaka emi-4 ukuya kweli-11 ubudala: Inhalation e-1 ye-Advair Diskus 100/50 kabini yonke imihla Unyango lolondolozo lweCOPD: Inhalation e-1 ye-Advair Diskus 250/50 kabini yonke imihla Idilesi yeHFA |
| Lude kangakanani unyango oluqhelekileyo? | Ixesha elide | Ixesha elide |
| Ngubani oqhelekileyo usebenzisa amayeza? | Abantu abadala nabantwana abaneminyaka eyi-6 nangaphezulu | Abantu abadala nabantwana abaneminyaka emi-4 nangaphezulu |
Imiqathango ephathwa yi-Symbicort kunye ne-Advair
I-Symbicort kunye ne-Advair zombini zivunyelwe i-FDA ukunyanga i-asthma kunye neCOPD. Nangona kunjalo, i-Advair Diskus ivunyiwe ukuba inyange isifuba kunye ne-COPD ngelixa i-Advair HFA ivunyiwe kuphela ukunyanga isifuba. I-Symbicort kunye ne-Advair zisetyenziselwa ukunyanga ii-inhalers ezisetyenziswa mihla le ukulawula kunye nokuthintela i-COPD kunye neempawu zesifuba, njengokuphefumla kancinci kunye nokuhefuzela.
Xa kusetyenziswa ixesha elide, la mayeza anokunceda ukunciphisa ubunzima kunye nokuhamba rhoqo kweCOPD kunye isifo sombefu , okanye ukunyusa. Ukulawulwa kwangoko kweempawu ezibukhali ze-COPD okanye i-asthma, umboneleli wezempilo uya kumisela i-inhaler yokuhlangula efana ne-albuterol, ekwabizwa ngamagama e-brand afana neVentolin kunye neProAir.
| Imeko | Uphawu | Idilesi |
| Isifo sombefu | Ewe | Ewe |
| ICOPD | Ewe | Ewe |
Ngaba iSymbicort okanye iAdvair isebenza ngakumbi?
Zombini iSymbicort kunye neAdvair zisebenza kakuhle xa zithathwa ngokungaguquguqukiyo. Zombini zinezinto ezifanayo ezisebenzayo ezinceda ukunciphisa ukudumba emiphungeni kunye nokuvula iindlela zomoya. Thetha nomboneleli wezempilo ukuze ufumane i-inhaler efanelekileyo esebenza kuwe.
Ngokwe- Uhlalutyo lweemeta I-inhaler ene-corticosteroid inhaled kunye ne-bronchodilator esebenza ixesha elide isebenza ngakumbi ekunciphiseni ukunyuka kwe-COPD kune-inhaler equkethe kuphela i-bronchodilator esebenza ixesha elide. Akukho zilingo zentloko-entloko ngokuthelekisa ngokuthe ngqo izithako ezisebenzayo kwiSymbicort kunye neAdvair eziye zahlaziywa kuhlalutyo. Nangona kunjalo, uphononongo lufumanise ukuba, ngokubanzi, inhalers yolondolozo lwendibaniselwano ziyasebenza ngokufanayo.
Olunye uvavanyo lweklinikhi olungenamkhethe, oluyimfama kabini lufumanise ukuba izithako ezisebenzayo kwiSymbicort naseAdvair zibonelela uphuculo olufanayo ekusebenzeni kwemiphunga, iintsuku zolawulo lwesifuba, kunye nomgangatho wobomi onxulumene nesifuba. Omabini la mayeza anciphise umngcipheko wokulaliswa esibhedlele okanye ukutyelelwa kwigumbi likaxakeka okubangelwa kukonyuka kweempawu zesifuba. Olu phononongo lwenziwe kubantu abangama-2,866 abaneminyaka eli-16 nangaphezulu ubudala.
Ukufunyanwa kunye nokuthelekiswa kweendleko zeSymbicort vs.Advair
I-Symbicort ihlala igutyungelwe luninzi lwezonyango kunye nezicwangciso zeinshurensi. Ikwafumaneka njengamayeza enziwe afana nalawo aveliswe ngumenzi, anokubiza ixabiso eliphantsi kunohlobo lwegama lebrendi. Ixabiso eliphakathi lokuthengisa ngeSymbicort lijikeleze i- $ 550. Unokwazi ukuthenga i-Symbicort malunga ne- $ 250 ngenkqubo yokonga okanye ikhadi lesaphulelo, njengekhadi le-SingleCare.
I-Advair nayo ihlanganiswe yi-Medicare kunye nezicwangciso ze-inshurensi. Njenge-Symbicort, i-Advair iza kwifom yohlobo oluqhelekileyo. Xa kuthelekiswa ne-Symbicort, ixabiso lentengiso le-Advair HFA linokuphakama libe malunga ne- $ 584. Ixabiso eliphakathi leAdvair Diskus lijikeleze i $ 494. Ungagcina kwiindleko zeAdvair HFA okanye iAdvair Diskus ngekhadi lekhuphoni ye-SingleCare kwiikhemesti ezithatha inxaxheba.
| Uphawu | Idilesi | |
| Ngokuqhelekileyo i-inshurensi? | Ewe | Ewe |
| Ngokuqhelekileyo ihlanganiswe yiCandelo le-Medicare? | Ewe | Ewe |
| Ubungakanani | 1 inhaler | 1 inhaler |
| I-Medicare copay eqhelekileyo | $ 19- $ 399 | Iidola ezi-2- $ 425 |
| Ixabiso elilodwa | $ 248 + | $ 288 + |
Iziphumo eziqhelekileyo ezichaphazelekayo zeSymbicort vs.Advair
Zombini iSymbicort kunye neAdvair zabelana ngemiphumo efanayo. Omabini la mayeza anokubangela iziphumo ebezingalindelekanga njengentloko ebuhlungu, i-nasopharyngitis, usulelo oluphezulu lokuphefumla, i-bronchitis, kunye nokudibana kwempumlo. Ezinye iziphumo ebezingalindelekanga zinokubandakanya isicaphucaphu, ukugabha, ukudakumba kunye nentlungu yomqolo.
Icandelo le-steroid le-Symbicort kunye ne-Advair linokunyusa umngcipheko we-thrush yomlomo, okanye usulelo lomngundo emlonyeni. Ngesi sizathu, kubalulekile ukuba uhlambe umlomo ngamanzi emva kokusebenzisa i-inhaler nganye. Isixhobo esibizwa ngokuba sispacer sinokuqhotyoshelwa kwii-inhalers zethamo lokulinganisa ukunceda ukunciphisa umngcipheko we-thrush yomlomo.
Iziphumo ebezingalindelekanga ezinokubakho ze-ICS / LABA amayeza zibandakanya i-paradoxical bronchospasm kunye ne-anaphylaxis. Unobangela bronchospasm exakayo ayiqondakali ngokucacileyo. Nangona kunjalo, inokwenzeka njengokuvela ngesiquphe kokuphefumla, ukuphefumla okufutshane, kunye nokukhohlela emva kokusebenzisa iyeza le-inhaler. I-Anaphylaxis inokwenzeka ngenxa yokungahambelani komzimba nakwezinye izithako kwi-Symbicort okanye kwi-Advair. Funa unyango kwangoko ukuba ufumana irhashalala, ukudumba, okanye ingxaki yokuphefumla emva kokudibanisa inhaler.
| Uphawu | Idilesi | |||
| Imiphumela | Iyasebenza? | Rhoqo | Iyasebenza? | Rhoqo |
| Intloko ebuhlungu | Ewe | 7% | Ewe | 12% |
| Nasopharyngitis | Ewe | Shumi elinanye% | Ewe | * |
| Usulelo oluphezulu lokuphefumula | Ewe | 8% | Ewe | 27% |
| IBronchitis | Ewe | 5% | Ewe | Mbini% |
| Ukuxinana kwempumlo | Ewe | 3% | Ewe | * |
| I-thrush yomlomo | Ewe | 1% | Ewe | 1% |
| Isicaphucaphu | Ewe | * | Ewe | 4% |
| Ukuhlanza | Ewe | 1% | Ewe | 4% |
| Ukurhabaxa | Ewe | * | Ewe | 5% |
| Umqolo obuhlungu | Ewe | 3% | Ewe | * |
* akuxelwa
Ukuphindaphinda akusekelwanga kwidatha ukusuka kuvavanyo lwentloko ukuya entloko. Olu alunakuba luluhlu olupheleleyo lweziphumo ezibi ezinokwenzeka. Nceda ujonge ugqirha wakho okanye umboneleli wezempilo ukuze ufunde okungakumbi.
Umthombo: DailyMed ( Uphawu ), Yonke imihla ( Idilesi )
Ukudibana kweziyobisi kweSymbicort vs.Advair
Isilumkiso sicetyiswa xa usebenzisa iSymbicort okanye iAdvair ngamayeza ayi-CYP3A4 inhibitors, anje nge-ritonavir, ketoconazole, kunye ne-clarithromycin. Ukuthatha i-CYP3A4 inhibitor nge-Symbicort okanye i-Advair kunokubangela ukonyuka kwamanqanaba egazi kwicandelo le-corticosteroid, elinokukhokelela kwiziphumo ezibi.
Sebenzisa i-monoamine oxidase inhibitors (i-MAOIs) okanye i-tricyclic antidepressants ene-Symbicort okanye i-Advair inokunyusa iziphumo zentliziyo yecandelo le-beta-agonist kulo naliphi na iyeza. Kwelinye icala, iibhloko ze-beta zinokunciphisa iziphumo ze-beta-agonist emiphungeni. I-diuretics inokubangela utshintsho lwe-electrocardiographic okanye amanqanaba asezantsi e-potassium (hypokalemia) xa isetyenziswa kunye neSymbicort okanye iAdvair.
| Iziyobisi | Iklasi yeziyobisi | Uphawu | Idilesi |
| Ritonavir Atazanavir Ketoconazole Clarithromycin Indinavir Itraconazole I-Nefazodone UNelfinavir Saquinavir | CYP3A4 inhibitors | Ewe | Ewe |
| Selegiline I-Rasagiline IPhenelzine Isocarboxazid | I-Monoamine oxidase inhibitors (MAOIs) | Ewe | Ewe |
| Amitriptyline Umgca weNortriptyline | I-Tricyclic yoxinzelelo | Ewe | Ewe |
| Imitha Atenolol Bisoprolol Nebivolol Ipropranolol | Ibhlokhi yeBeta | Ewe | Ewe |
| Furosemide Bumetanide I-Torsemide IChlorthalidone | Womchamo | Ewe | Ewe |
Nxibelelana noochwephesha kwezolunye unxibelelwano olunokubakho ngeziyobisi.
Izilumkiso zeSymbicort kunye neAdvair
Ngenxa yokuba ziqulathe i-corticosteroid, iSymbicort kunye neAdvair kunokubangela ukonyuka komngcipheko wosulelo okanye ukunciphisa uxinano lwamaminerali ethambo. Nangona kunjalo, xa kuthelekiswa ne-systemic corticosteroids, inhaled corticosteroids inobungozi obuncinci beziphumo ebezingalindelekanga. Ukucinezelwa kwe-Adrenal kunokwenzeka kwakhona xa usebenzisa idosi ephezulu yeSymbicort okanye iAdvair.
Ukusetyenziswa kwexesha elide kwe-Symbicort okanye i-Advair kunokunyusa umngcipheko we-glaucoma okanye i-cataract. Ingcali yamehlo inokufuna ukubonwa ukuba ngaba iimpawu zamehlo zikhula ngokuhamba kwexesha kunye nokusetyenziswa kwalamayeza.
Ukusetyenziswa kweSymbicort okanye iAdvair kufuneka kubekwe esweni kwizigulana ezinengxaki yeentliziyo, ukuphazamiseka kwenkqubo ye-neva, ukuphazamiseka kwesifo kunye neswekile. Thetha nomboneleli wezempilo ngezinye izilumkiso kunye nezilumkiso ngaphambi kokusebenzisa iSymbicort okanye iAdvair.
Imibuzo ebuzwa rhoqo malunga neSymbicort vs.
Yintoni iSymbicort?
I-Symbicort ligama elinegama lophawu olwenziwe yi-AstraZeneca. Iqulethe i-budesonide kunye ne-formoterol, enceda ekuthinteleni nasekulawuleni iimpawu zesifuba kunye neCOPD. I-Symbicort yamkelwe ukunyanga isifuba kwizigulana ezineminyaka emi-6 nangaphezulu. Iyafumaneka njenge-inhalation aerosol esetyenziswa kabini yonke imihla.
Yintoni iAdvair?
I-Advair ligama elinegama lophawu olwenziwe nguGlaxoSmithKline. Iqukethe i-fluticasone kunye ne-salmeterol. I-Advair yi-FDA evunyiweyo ukukhusela kunye nokulawula iimpawu zeCOPD kunye nesifuba. Kuvunyiwe ukunyanga isifuba kwizigulana ezineminyaka emi-4 nangaphezulu. I-Advair ifumaneka njengomgubo we-inhalation (Advair Diskus), onokuthi unyange isifuba kunye ne-COPD, kunye ne-inhalation aerosol (Advair HFA), evunyiweyo ukunyanga isifuba. Zombini iifomula zisetyenziswa kabini yonke imihla.
Ngaba iSymbicort kunye neAdvair ziyafana?
I-Symbicort kunye neAdvair zisetyenziselwa ukunyanga isifuba kunye neCOPD. Nangona kunjalo, ziqulathe izinto ezahlukeneyo ezisebenzayo. I-Symbicort iqulethe i-budesonide kunye ne-formoterol ngelixa i-Advair iqulethe i-fluticasone kunye ne-salmeterol. I-Symbicort inokunyanga isifuba kwizigulana ezineminyaka emi-6 nangaphezulu ngelixa i-Advair inganyanga isifuba kwizigulana ezineminyaka emi-4 nangaphezulu I-Advair ikwafumaneka njenge-inhalation powder okanye i-aerosol ngelixa i-Symbicort ifumaneka kuphela njenge-inhalation aerosol.
Ngaba iSymbicort okanye iAdvair ingcono?
Zombini i-Symbicort kunye ne-Advair ziyasebenza ekunyangeni i-COPD kunye neempawu zesifuba. Ngenxa yokuba amayeza olondolozo, kufuneka asetyenziswe yonke imihla ukuze asebenze ngokukuko. Eyona inhaler yolondolozo ilungileyo kufuneka ichongwe ngokujonga izinto ezinje ngeziphumo ebezingalindelekanga ezinokubakho, idosi, kunye neendleko.
Ngaba ndingayisebenzisa iSymbicort okanye iAdvair ngelixa ndikhulelwe?
Akukho phando lwaneleyo lokucebisa ukuba iSymbicort okanye iAdvair ikhuselekile okanye iyingozi ngexesha lokukhulelwa. Ngokwe-Asthma kunye neAllergy Foundation yaseMelika (AAFA), ii-agonists ze-beta ezisebenza ixesha elide zezi ayikhuthazwa njengonyango lodidi lokuqala lwesifo sombefu kwizigulana ezikhulelweyo. Endaweni yoko, i-bronchodilator emfutshane esebenza inokucetyiswa endaweni yoko. Qhagamshelana nomboneleli wezempilo malunga neengcebiso zonyango kwi-COPD kunye nokunyanga kwe-asthma xa ukhulelwe.
Ndingayisebenzisa iSymbicort okanye iAdvair ngotywala?
Utywala abaziwa ngokusebenzisana neSymbicort okanye iAdvair. Ukusetyenziswa kotywala okungapheliyo kunokuphazamisa amandla omzimba wokulwa nezifo, ezinokuthi zikhule njengesiphumo sokuba mandundu kwesifuba okanye i-COPD. Thetha nomboneleli wezempilo malunga nokuba kukhuselekile ukusela utywala ngelixa usebenzisa iSymbicort okanye iAdvair.
Yeyiphi inhaler elingana neSymbicort?
Uhlobo oluqhelekileyo lweSimbicort luyafumaneka. Inguqulelo yohlobo oluqhelekileyo, equlathe i-budesonide kunye ne-formoterol, ilingana ne-Symbicort. Inguqulelo yohlobo oluqhelekileyo nayo isenokuba yenye yexabiso eliphantsi kwigama lophawu inhaler. I-inhalers efanayo kwi-Symbicort ibandakanya iAdvair (fluticasone / salmeterol), iDulera (mometasone / formoterol), kunye neBreo (fluticasone / vilanterol). Ezi inhalers zinokusebenza ngokufanayo kwi-Symbicort, kodwa azithathwa njengezifana ne-Symbicort.
Yeyiphi eyona inhaler ikhuselekileyo kwiCOPD?
I-ICS / LABA indibaniselwano ye-inhalers ithathwa njengefanelekileyo kwaye ikhuselekile kunyango lwe-COPD. Nangona kunjalo, ii-corticosteroids ezinganyangekiyo zithwala umngcipheko wenyumoniya kubantu abane-COPD ephambili. I-LAMA / LABA indibaniselwano ye-inhalers ithathwa njengefanelekileyo kwaye ikhuselekile Ngaphandle kwe-ICS / LABA yokudibanisa inhalers ngesi sizathu. I-LAMA / LABA indibaniselwano ye-inhalers ibandakanya i-Anoro (umeclidinium / vilanterol), iStiolto (tiotropium / olodaterol), kunye ne-Bevespi (glycopyrrolate / formoterol).
