Trulicity vs Victoza: Umahluko ophambili kunye nokufana

Iziyobisi Vs. Umhlobo

I-Trulicity kunye ne-Victoza ngamayeza amabini angenayo i-insulin engenayo esetyenziselwa ukunyanga amanqanaba eswekile yegazi kwabo bachaphazeleke kuhlobo lweswekile yesi-2. Ziyinxalenye yodidi lwamayeza amatsha abizwa ngokuba yi-GLP-1 (glucagon-like peptide) agonists. I-Trulicity kunye neVictoza ngokuyimfuneko zisebenza ngokuphucula ukukhutshwa kwe-insulin xa amanqanaba eswekile ephezulu kakhulu. Banokunyusa iimvakalelo zokuhlutha, ukuvumela ukuba uzive ugcwele ngakumbi emva kwesidlo esinokunceda ukunciphisa umzimba.

Ubunzima

I-Trulicity ligama lophawu lwe-dulaglutide, eyaqala yamkelwa ngo-2014. Nangona ilunyango olusebenzayo kuhlobo lwesibini lweswekile, ayikhuthazwa njengonyango lodidi lokuqala. Xa isetyenziswa ecaleni kokutya kunye nokuzilolonga, iTrulicity inokunceda ekuphuculeni ulawulo lwe-glycemic.

I-Trulicity yonyango elitofwayo elilawulwa kube kanye ngeveki. Inokujova phantsi kolusu nangaliphi na ixesha losuku. Iindawo eziqhelekileyo zenaliti ngumlenze, isisu, okanye ingalo ephezulu.

I-Trulicity iza yenziwe njengepeni yethamo elinye okanye isirinji ekhethiweyo ene-0.75 mg / 0.5 mL okanye i-1.5 mg / 0.5 ml. Iidosi zihlala ziqala kwi-0.75 mg kanye ngeveki, kodwa zinokunyuswa ziye kwi-1.5 mg kanye ngeveki ukuba ziyafuneka.

UVictoza

IVictoza, ekwabizwa ngokuba yi-liraglutide, yi-GLP-1 agonist enesitofu evunyiweyo ngo-2010. Ikwaboniswa ukuphucula amanqanaba eswekile yegazi kuhlobo 2 lweswekile. Ngokungafaniyo neTrulicity, iVictoza inokusetyenziselwa ukunciphisa umngcipheko weziganeko zentliziyo, ezinje ngokuhlaselwa sisifo sentliziyo kunye nokubetha, kubantu abadala abanesifo seswekile kunye nesifo sentliziyo.

I-Victoza ilawulwa njengenaliti ngendlela efanayo neTrulicity. Nangona kunjalo, ilawulwa kube kanye yonke imihla endaweni yokuba kube kanye ngeveki. Inokujova ethangeni, esiswini, okanye kwingalo ephezulu.

I-Victoza iyafumaneka njenge-6 mg / mL ezaliswe kwangaphambili, idosi ezininzi ezinokulawulwa ngeedosi ezahlukeneyo ze-0.6 mg, 1.2 mg, okanye 1.8 mg. Njengezinye ii-agonists ze-GLP-1, iVictoza ihlala iqaliswa kwidosi esezantsi kwaye ifakwa kumthamo ophezulu njengoko kufuneka kunyango olongezelelweyo.

I-Trulicity vs iVictoza esecaleni ngokuthelekisa icala

I-Trulicity kunye neVictoza zimbini ze-GLP-1 agonists ezineempawu ezifanayo. Ngelixa zifana ngeendlela ezininzi, zikwanokwahluka ekufuneka zikwazi. Ungawajonga kwakhona la mayeza kwitheyibhile yokuthelekisa engezantsi.

Ubunzima	UVictoza
Umiselwe i
Uhlobo lwe-2 yeswekile	Uhlobo lwe-2 yeswekile Umngcipheko weentliziyo
Ulwahlulo lweziyobisi
I-GLP-1 receptor agonist	I-GLP-1 receptor agonist
Umenzi
UEli Lilly	Novo Nordisk
Iziphumo eziqhelekileyo
Isicaphucaphu Urhudo Ukuhlanza Intlungu zesisu Ukunciphisa ukutya	Isicaphucaphu Urhudo Ukuhlanza Ukunciphisa ukutya Ukutya Ukuqunjelwa Usulelo oluphezulu lokuphefumula
Ngaba ikhona igeneric?
Akukho generic ikhona	Akukho generic ikhona
Ngaba ihlawulwa yi-inshurensi?
Iyahluka ngokomboneleli wakho	Iyahluka ngokomboneleli wakho
Iifom zedosi
Isisombululo esingaqhelekanga	Isisombululo esingaqhelekanga
Ixabiso leMali eliPhakathi
$ 806 (nge-2, 0.5ml ye-1.5mg / ye-0.5ml yeepen)	$ 995 (nge-3, 3 ml ye-18 mg-3 ml yeepeni)
Ixabiso lesaphulelo esisodwa
Ixabiso leTrulicity	Ixabiso likaVictoza
Ukusebenzisana kweziyobisi
Amayeza omlomo (xa ethathwa kunye ngenxa yokuncitshiswa kokufakwa kwe-GLP-1 agonists) Amayeza Antidiabetic	Amayeza omlomo (xa ethathwa kunye ngenxa yokuncitshiswa kokufakwa kwe-GLP-1 agonists) Amayeza Antidiabetic
Ngaba ndingasebenzisa ngelixa ndicwangcisa ukukhulelwa, ukukhulelwa, okanye ukuncancisa?
Trulicity ikudidi lokukhulelwa C. Akukho datha yomntu yokuvavanya iTrulicity kwizigulana ezikhulelweyo. Nxibelelana nogqirha malunga nokuthatha iTrulicity ngelixa ukhulelwe okanye uncancisa.	UVictoza ukwicandelo lokukhulelwa C. Akukho datha yomntu yokuvavanya iVictoza kwizigulana ezikhulelweyo. Nxibelelana nodokotela malunga nokuthatha uVictoza ngelixa ukhulelwe okanye uncancisa.

Isishwankathelo

Zombini i-Trulicity kunye ne-Victoza zi-GLP-1 agonists ezisetyenziselwa ukunyanga amanqanaba eswekile yegazi kwabo bane-2 yeswekile. I-Victoza inokusetyenziselwa ukunciphisa umngcipheko wokuhlaselwa sisifo sentliziyo kunye nokubetha ukuba unohlobo lweswekile yesibini kunye nesifo sentliziyo. Omabini la mayeza ayasebenza ekulawuleni iswekile yegazi ephezulu kwaye ubukhulu becala yahlukile kwiziphumo ebezingalindelekanga kunye nedosi.

Ngelixa omabini la mayeza elawulwa ngenaliti, ahlukile kubungakanani bedosi. Trulicity ilawulwa kube kanye ngeveki ngelixa iVictoza ilawulwa kube kanye yonke imihla. Omabini la mayeza anokujova nanini na emini kwaye angathathwa kunye okanye ngaphandle kokutya.

Omabini la mayeza anemingcipheko efanayo ye-hypoglycemia, okanye iswekile esegazini eyingozi, ukuba athathwe namanye amayeza eswekile. I-GLP-1 agonists akufuneki ithathwe ngaxeshanye namanye amayeza omlomo ngenxa yokuncipha kokufakwa emathunjini. Ngelixa iziphumo ebezingalindelekanga zinokufana kuwo omabini amachiza, ukungagayeki kunye nokuqunjelwa kunokuba yinto exhaphakileyo ngokusetyenziswa kweVictoza.

I-Trulicity kunye neVictoza azikhuthazwa ukuba unembali yomhlaza wedlala lengqula ngenxa yomngcipheko okhulayo wamathumba e-thyroid ahambelana nala mayeza. Banesilumkiso sepancreatitis, okanye ukudumba kwepancreas, kunye nokwenzakala okukhulu kwezintso. Ke ngoko, ukubekwa esweni kwesiqhelo kwepancreas kunye nezintso kufuneka kwenziwe ngugqirha ukunqanda le mngcipheko.

Ulwazi oluchazwe apha lwenzelwe ukukunika uthelekiso phakathi kwamayeza amabini e-antidiabetic. Kuya kufuneka uxoxe ngemeko yakho iphela nogqirha wakho ukumisela ukuba leliphi iyeza elinokukusebenzela.