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Funda ukubona iimpawu zeserotonin syndrome

Imfundo yezeMpilo

Masithi uthatha amayeza Uxinzelelo , njenge Paxil (paroxetine), yonke imihla. Uziva a migraine iyeza, ke umba kwidrowa ukhangela i Imitrex (sumatriptan) ithebhulethi.

Okanye, enye imeko eqhelekileyo-uthatha i-anti-depressant ICymbalta (duloxetine), kwaye uziva ubanda kwaye ukhohlela uza. Ufikelela kwibhotile ye I-Robitussin-DM ukunyanga iimpawu zakho.

Ezi zinto zibonakala zingenabungozi, akunjalo? Cinga kwakhona. Ezi meko zokuxuba amayeza zinokubangela into ebizwa ngokuba yi-serotonin syndrome, enokusongela ubomi.

ISerotonin yintsholongwane. Ukudakumba kuhlala kunxulunyaniswa namanqanaba asezantsi e-serotonin. Unyango oluninzi lwe ukudakumba ukunceda ukwandisa amanqanaba e-serotonin. Amanye amayeza (anje ngamayeza athile e-migraine, amayeza eentlungu, okucinezelela ukukhwehlela, kunye nezongezo zokutya) zinokunyusa amanqanaba e-serotonin.

Ukuba uthatha iyeza elonyusa i-serotonin, unokuziva ulungile. Kodwa, i-serotonin eninzi evela kwidosi ephezulu kakhulu, okanye ekuthatheni amayeza amabini okanye nangaphezulu anyusa amanqanaba e-serotonin, kunokubangela i-serotonin syndrome.

Yintoni i-serotonin syndrome?

Iserotonin syndrome yenzeka xa kukho serotonin eninzi kwinkqubo yakho. Ufumana njani i-serotonin eninzi emzimbeni wakho?

Iserotonin syndrome inokwenzeka xa umntu:

Ithatha ngaphezulu kwelinye iyeza elichaphazela amanqanaba e-serotonin
Iqala okanye inyusa idosi yeyeza elonyusa i-serotonin
Ithatha iyeza elininzi kakhulu elonyusa i-serotonin (ngengozi okanye ngenjongo)

Xa ishiywe inganyangwa, iziphumo zinokuba nzima.

Ngawaphi amayeza anokubangela i-serotonin syndrome?

La mayeza alandelayo anyusa amanqanaba e-serotonin kwaye anokubandakanyeka kwimeko ye-serotonin syndrome. Iserotonin syndrome inokwenzeka ngakumbi ukuba uthathe indibaniselwano ezimbini okanye nangaphezulu zala machiza.

I-SSRI yoxinzelelo: I-SSRIs (i-serotonin reuptake inhibitors ekhethiweyo) zezona ziyobisi zixhaphakileyo kwi-serotonin syndrome. Babandakanya iProzac (i-fluoxetine), i-Paxil (i-paroxetine), i-Zoloft (i-sertraline), i-Celexa (i-citalopram), i-Lexapro (i-escitalopram), i-Luvox (i-fluvoxamine) kunye ne-Trintellix.
I-SNRI yoxinzelelo: I-SNRIs (i-serotonin-norepinephrine reuptake inhibitors) ibandakanya iCymbalta (duloxetine), iEffexor (venlafaxine), kunye nePristiq (desvenlafaxine).
Olunye udandatheko: Amayeza e-Tricyclic antidepressant (amitriptyline, nortriptyline), bupropion, trazodone, MAOIs (monoamine oxidase inhibitors)
Iipilisi zentlungu zeOpioid : njengePercocet, i-oxycodone, i-OxyContin, i-Ultram (i-tramadol), i-Demerol (i-meperidine), i-fentanyl, i-Vicodin
Ukukhohlisa Nawuphi na umkhuhlane / amayeza abandayo aqukethe i-dextromethorphan, enje ngeRobitussin-DM, i-promethazine DM, iDelsym, iMucinex-DM
Imithi ye-Migraine: IiTriptans ezinje ngeAmerge (naratriptan), Imitrex (sumatriptan), Relpax (eletriptan), Zomig (zolmitriptan), Axert (almotriptan)
Amanye amayeza amiselweyo: Metoclopramide, ondansetron, linezolid
Izongezo zemifuno: IGinseng, iSt John's Wort
Iziyobisi ezingekho mthethweni: I-ecstasy, i-LSD, icocaine

Ixhaphake kangakanani i-serotonin syndrome?

Iingcali Andiqinisekanga kwenani lamatyala e-serotonin syndrome. Kungenxa yokuba iimeko ezinobulali zinokungahoywa okanye ukuhoywa. Iimeko ezinzima kakhulu zinokubangelwa sesinye isizathu. Siyazi ukuba isifo se-serotonin sinokubakho nakweyiphi na iminyaka, kwaye njengoko ukusetyenziswa kwe-antidepressant kuyanda, iimeko ze-serotonin syndrome ziyanda.

Zithini iimpawu zeserotonin syndrome?

Iimpawu zesifo seSerotonin zikhula ngokukhawuleza emva kokuthatha iyeza lokuthintela- ama-60% amatyala enzeka kwisithuba seeyure ezintandathu. Uninzi lwezigulana zineempawu ngaphakathi kweeyure ezingama-24.

Iimpawu zinokwahluka ukusuka kubumnene ukuya ekusongeleni ubomi kwaye zinokubandakanya:

Ukuphazamiseka
Ixhala
Ukungazinzi
Utshintsho lwemood / utshintsho kwimeko yengqondo
Ukudideka okanye ukudideka
Ukuphulukana nokulungelelaniswa kwemisipha
Ukubila okanye ukungcangcazela
Ulusu olugudileyo
Ifiva
IHyperthermia (ubushushu)
Ukunyuka kwentliziyo, uxinzelelo lwegazi oluphezulu
Isicaphucaphu, ukugabha, urhudo
Ukungcangcazela
Ukuqina kwemisipha, ukuqina kwemisipha, okanye izihlunu zemisipha, ngakumbi emilenzeni
Ukucinga okuqinisekileyo
Abafundi abaqaqambileyo

Iimpawu ezinzima ze-serotonin syndrome zibandakanya umkhuhlane omkhulu, ukuxhuzula, ukubetha kwentliziyo ngokungaqhelekanga kunye nokungabikho zingqondweni.

Ezinxulumene: Bubuphi ubushushu bomzimba obuthathwa njengomkhuhlane?

Yintoni omele uyenze ukuba ucinga ukuba une-serotonin syndrome

Ukuba uthatha iyeza elichaphazela amanqanaba e-serotonin kunye namava ezi mpawu zingasentla, funa unyango kwangoko kwiziko lokhathalelo olungxamisekileyo okanye kwigumbi lexakeka. Iimeko ezinzima zisongela ubomi kwaye zinokuqhubela phambili ngokukhawuleza ziye ekufeni.

Umboneleli wezononophelo lwempilo oqhele ukubona isifo se-serotonin ngokwezonyango, ngokuvavanya iimpawu zakho kunye nokuphonononga amayeza owathathayo (zombini amayeza kunye ne-counter-counter). Abanye oogqirha basebenzisa i I-Hunter Serotonin Iikhrayitheriya zetyhefu ukunceda ekuchongeni isifo se-serotonin.

Luthini unyango lwe-serotonin syndrome?

Funa unyango kwangoko lweempawu zesifo se-serotonin.
Ukuba uneempawu ezincinci, umboneleli wakho wezempilo uya kukucebisa ukuba uyeke iyeza okanye iziyobisi ezibangela impendulo ngokukhawuleza. Ukuba unezinto ezininzi malunga neempawu ezinzima, kuya kufuneka unyangwe kwaye ugadwe esibhedlele. Unyango lwe-serotonin syndrome luxhomekeke kwiimpawu kunye nobunzima beempawu.

Amanye amayeza ayeqhele ukwenza unyango iimpawu zibandakanya:

I-Benzodiazepines (njenge mzantsiweb ) ukunceda ukuphazamiseka, ukuxhamla kunye nokuqina
ICyproheptadine ukuvimba imveliso ye-serotonin
Amayeza okunciphisa ukubetha kwentliziyo yakho okanye uxinzelelo lwegazi (okanye uphakamise uxinzelelo lwegazi ukuba liphantsi kakhulu)

Unokufuna i-IV fluids yokuphelelwa ngamanzi emzimbeni kunye nomkhuhlane, okanye ioksijini eyongezelelweyo.

Ihlala ixesha elingakanani i-serotonin syndrome?

Ubungakanani bexesha onokufumana ngalo i-serotonin syndrome iyahluka. Ukuba unesimo esifanelekileyo sesifo se-serotonin, unokuziva ungcono kwintsuku enye ukuya kwiintsuku ezintathu. Ezinye iimeko zinokuthatha iiveki ezimbalwa ukuba zihambe, kuxhomekeke kweliphi iyeza (ii) ezibangele impendulo kunye nokuba zihlala ixesha elingakanani emzimbeni wakho.

Ugqirha wosapho waseMelika uyacacisa ukuba u unako ukubuyela kwimeko yesiqhelo kwi-serotonin syndrome, ukuba iyaqatshelwa ngokukhawuleza kwaye iingxaki zilawulwa kakuhle.

Ngaba i-serotonin syndrome inokubangela umonakalo wexesha elide?

Inkqubo ye- Iindaba ezimnandi kukuba phantse kuzo zonke iimeko, ukuba isifo sibhaqwe kwangethuba, akufuneki kubekho iziphumo ebezingalindelekanga zexesha elide, ngokweengcali zesibhedlele.

Ngenxa yokubaluleka kokunyanga i-serotonin syndrome kwangethuba, kubalulekile ukuba ufumane unyango kwangoko ukuba uneempawu.

Ungayiphepha njani i-serotonin syndrome

Nabani na othatha iyeza elonyusa i-serotonin usemngciphekweni wesifo se-serotonin.

Ukukhusela kwakho, fumana onke amayeza akho kwikhemesti enye. Ngale ndlela, usokhemesti unokukwazi kwaye abe noluhlu lwakho olupheleleyo lwamayeza ukukhusela ukuhlangana kweziyobisi.
Ukuba unayo nayiphi na inguqu kwirejimeni yakho yamayeza, njengokuqalisa iyeza elitsha, soloko unxibelelana nosokhemesti wakho ukuze uqiniseke ukuba awuphindi kwi-serotonin.
Ukuba uthatha amayeza anyusa i-serotonin, yazi iimpawu zesifo se-serotonin. Funa unyango ngokukhawuleza ukuba unempawu.
Ukuba ufuna iyeza elibandayo / lokukhohlela kwaye sele uthatha ichiza elonyusa amanqanaba e-serotonin, jonga izithako, kwaye uphephe i-dextromethorphan. Usokhemesti wakho unokukunceda ukhethe imveliso efanelekileyo.
Amayeza amaninzi ahlukeneyo achaphazela amanqanaba e-serotonin. Utshintsho kumthamo okanye indibaniselwano yamayeza amabini anyusa zombini i-serotonin kunokubangela i-serotonin syndrome, enokusongela ubomi.

Soloko ujonga umboneleli wakho wezempilo ukuqinisekisa ukuba amayeza owathathayo ayahambelana.