Iziphumo ebezingalindelekanga ze-Ativan kunye nokunxibelelana, kunye nendlela yokuzikhusela

Ulwazi lweziyobisi

Ukuba unayo ixhala , mhlawumbi uvile Ativan . Okwangoku, usenokungazi ukuba iAtivan iyanceda nokulala, inokuthintela isicaphucaphu ngexesha lonyango lwe-chemotherapy, kwaye isetyenziselwa ukunyanga imeko yokuxhuzula. I-Ativan, igama lophawu lonyango i-lorazepam, liyeza elisebenza ngokukhawuleza, uninzi lwabantu luqala ukuziva ngathi luneziphumo ezipholileyo phakathi kwemizuzu engama-20 ukuya kwengama-30 emva kokuyithatha. Njengamayeza amaninzi, iAtivan ineziphumo ebezingalindelekanga kwaye inokusebenzisana namanye amachiza. Kule nqaku, sixoxa ngeziphumo ebezingalindelekanga ezinokubakho zeAtivan, ukuhlangana kweziyobisi, kunye nezilumkiso zokusebenzisa ngokukhuselekileyo.

Yintoni iAtivan?

Ativan (ilorazepam) ukwiklasi yonyango ebizwa ngokuba yi-benzodiazepines. Iyafumaneka njengeyeza likagqirha. Yamkelwe e-US kolu nyango lulandelayo:

• Uncedo lwexeshana elifutshane lweempawu zokuphazamiseka koxinzelelo kunye noxinzelelo olunxulumene noxinzelelo
• Ulawulo lweengxaki zoxinzelelo

Ngamanye amaxesha oogqirha bayamisela off-ileyibheli , Kuthetha ukuba nangona kungavunyelwanga ukunyanga imeko ethile yonyango, ubungqina be-anecdotal bufumene buluncedo. Ngokwe- Iziko leLizwe leNgcaciso yeBiotechnology , le miqathango ibandakanya:

• Isifo sokurhoxisa utywala kunye ne-delirium
• Ukuphazamiseka kwengqondo
• Ukuthintela isicaphucaphu ngexesha lonyango lomhlaza
• Ukudumba kwezihlunu
• Ukuphumla kunye nokuthambisa ngaphambi kokubulawa komzimba
• Catatonia yengqondo
• Ukusetyenziswa kwexesha elifutshane lokulala
• Isimo sokuxhuzula

I-Ativan isebenza ngokukhawuleza. Xa uthatha ngomlomo, uninzi lwabantu luqala ukuziva iziphumo kwimizuzu engama-20 ukuya kwengama-30. I-Ativan iyasebenza ngaphakathi kwemizuzu enye ukuya kwemithathu xa inikwe ngaphakathi.

ZIQHELEKILEYO: Unyango kunye neyeza

Kutheni le nto ilorazepam iyinto elawulwayo?

Kukho umngcipheko wokuxhatshazwa kunye nokuxhomekeka e-Ativan. Iunited States Ukutya kunye noLawulo lweziyobisi (FDA) Ubhale iAtivan njengeShedyuli IV into elawulwayo . Kukho amanqanaba amahlanu ezinto ezilawulwayo ezisekwe kumngcipheko wokusetyenziswa gwenxa kweziyobisi okanye ukwenzakala, ngokungathi ichiza linokubangela ukuxhomekeka kwengqondo okanye komzimba. Ishedyuli I inamandla aphezulu okusetyenziswa gwenxa kweziyobisi, njengeheroin. La machiza akafumanekanga ekusebenziseni unyango kwaye akukho semthethweni eUnited States. Ishedyuli V iziyobisi zinamandla aphantsi okuphathwa gadalala, njengeziraphu ezithile zokukhohlela ezinekhowudi. IiBenzodiazepines ezinje ngeAtivan zikwiShedyuli IV, oko kuthetha ukuba banokubanakho ukusetyenziswa gwenxa kweziyobisi, kunye nokusetyenziswa okufanelekileyo kwezonyango. Amanye amayeza akolu luhlu abandakanya iXanax (alprazolam), iKlonopin (clonazepam), kunye neValium (diazepam).

Ngaba iAtivan sisiyobisi?

Nangona iyinto elawulwayo, iAtivan ayisiyo narcotic. I-Narcotic inciphisa imbono yomntu ngeentlungu, ngelixa i-benzodiazepines ineziphumo zokuthomalalisa. Zombini ii-narcotic kunye ne-benzodiazepines zinokubangela imikhwa. Nangona oogqirha bejonga iAtivan ikhuselekile kwaye isebenza xa isetyenziswa njengokuyalelwa, ukuxhomekeka emzimbeni kunokukhula ngokukhawuleza kwiiveki ezimbini, ngokwe Umbutho weSizwe kuManyano lweNgqondo (i-NAMI) .

Iziphumo eziqhelekileyo ezichaphazelekayo zeAtivan

Iziphumo ebezingalindelekanga zeAtivan zihlala zibukhali ngakumbi ngeedosi eziphezulu. Ezinye zeempembelelo eziqhelekileyo zibandakanya:

• Ukuba nesiyezi
• Ukozela okanye ukozela
• Ukuhlala
• Ubumhlophe
• Ukungazinzi
• Ukwehla kokukwazi ukugxila
• Ubuthathaka bemisipha
• Umlomo owomileyo

Ukucutha uxinzelelo lwegazi sisiphumo esisecaleni se-Ativan, kodwa ayimiselwanga ukunciphisa uxinzelelo lwegazi, kucacisa UAmanda Brown , NP, ugqirha ongumongikazi wezempilo yengqondo kwisibhedlele saseNew York-Presbyterian kwaye unxulumana neziko i-Columbia University Irving Medical Centre.

I-Ativan inokubangela nokuphazamiseka kokulala, ukungasebenzi kakuhle kwe-erectile, kunye notshintsho kumdla wokutya.

I-Ativan isebenza ngokuzola inkqubo ye-nervous ukulinganisa umsebenzi kwingqondo, ukukhuthaza ukuphumla nokuzola. Ikwenyusa i-dopamine, kwaye xa ithathwa ngeedosi eziphezulu, ii-neurotransmitters zokuziva ulungile kwingqondo ziyanda, zibangela imvakalelo ye-euphoric, esisesinye sezizathu zokuba ikhoboka.

Iziphumo ebezingalindelekanga ezimandundu zeAtivan

Abanye abantu banokufumana okungakumbi iziphumo ebezingalindelekanga ezimandundu Ukusetyenziswa kweAtivan. Oku kubandakanya:

• Ukuxova ukuhamba
• Iinyikima okanye ukungakwazi ukuhlala uzolile
• Ifiva
• Iingxaki zokuphefumla
• Kunzima ukugwinya
• Ukudumba kolusu okanye imihlambi
• Mthubi ulusu okanye amehlo
• Ukubetha kwentliziyo ngokungaqhelekanga
• Ukuphulukana nenkumbulo okanye iingxaki zememori
• Ukudideka
• Ukulala kwe-apnea okanye ukugula kwe-apnea yokulala

Uninzi lwexesha, iziphumo ebezingalindelekanga ziyancipha njengoko isiphumo sonyango sincipha, ngesiqhelo kwiiyure ezintandathu ukuya kwezisibhozo. Nangona kunjalo, ukuba uneziphumo ebezingalindelekanga ezimandundu okanye iziphumo azihambi ngaphakathi kweeyure ezimbalwa, kuya kufuneka ufumane unyango.

Iziphumo ebezingalindelekanga zokuba amayeza ayeke zibandakanya ukulala kakhulu, ukulahleka kwememori, ukuba nochuku, ukulungelelana okungalunganga, kunye nesiyezi, utshilo uBrown. Kuba ukumisa ngequbuliso iAtivan kunokubangela iimpawu zokurhoxa, kuya kufuneka uthethe nogqirha wakho ngaphambi kokuyeka.

Izilumkiso zika-Ativan

I-Ativan yonyango lwexesha elifutshane. Xa imiselwe ukusetyenziswa kwemihla ngemihla, ikhosi yonyango ekhuthazwayo ziiveki ezine okanye ngaphantsi.

Iimpawu zokurhoxa kuka-Ativan

Ukusetyenziswa kwexesha elide kunokukhokelela ekuxhomekekeni nasekunyamezelaneni, okuthetha ukuba umntu unokufuna idosi ephezulu ukuze abe nesiphumo esifanayo okanye anokufumana ukurhoxa ekungathatheni iyeza, utsho UWendi D. Jones , Pharm. D., usokhemesti eMantla Carolina. Ngokwengqondo, kunokuba nzima ngakumbi ngaphandle kwesiyobisi, kukhokelela kukonyuka koxinzelelo. Ukuyeka iyeza emva kweeveki ezimbalwa zokusebenzisa akufuneki kubangele iingxaki ezinkulu. Nangona kunjalo, ukuba usebenzisa iyeza ixesha elingaphezu kweeveki ezimbini ukuya kwezine, ukuxhomekeka kunokwenzeka, kwaye ukucima oko kunokufuneka.

Uxinzelelo

Abanye abantu, iAtivan inokuzandisa iimpawu zoxinzelelo. I-Ativan yinkqubo ye-nervous system edandathekisayo. Xa isakha kwinkqubo yakho okanye ukuba uyithatha ngeedosi eziphezulu, kunokwenzeka ukuba uxinzelelo lube mandundu kwaye lude lubangele neengcinga zokuzibulala okanye iimvakalelo. Ulwazi lweziyobisi luchazwe kwifayile ye- faka iphakheji ibonisa ukuba i-Ativan kufuneka isetyenziswe kuphela kwizigulana ezinokudakumba xa isigulana sikunyango loxinzelelo.

Izithintelo zobudala

I-Ativan ivuliwe Uluhlu lweeKhrayitheriya zoBhiya iziyobisi ezinokuthi zingafaneleki kubantu abadala.Abantu abadala abadala bonyuse uvakalelo kwi-benzodiazepines. Kwezi zigulana, kukho umngcipheko okhulayo wokuphazamiseka kwengqondo, ukuphazamiseka kwengqondo, ukuwa, ukwaphuka, kunye nokuphazamiseka kwemoto xa kusetyenziswa iAtivan. Ngaphandle kokuba kuLuhlu lweBhiya, iAtivan ihlala imiselwa kubantu abadala. Kwezi zigulana, kufuneka kusetyenziswe elonaqondo lisezantsi kunene kwaye isiguli kufuneka sibekwe iliso elibukhali.

Ngenxa yokuba i-lorazepam iyalalisa, akufuneki uqhube imoto okanye usebenzise oomatshini de ube uyazi ukuba lukuchaphazela njani eli yeza.

Ukuphazamiseka kwimemori

Kukwakho nolwazi oluphikisanayo malunga nokuba ingaba iAtivan ibangela okanye iyingozi yomonakalo kwimemori okanye isifo se-Alzheimer's. Isifundo esinye ifumanise ukuba i-benzodiazepines inokuba ngumngcipheko wesifo sengqondo esixhalabisayo. Kwaye enye isifundo, epapashwe kwi-2014 , Ufumene umbutho phakathi kokuthatha i-lorazepam kunye nomngcipheko wesifo se-Alzheimer's. Nangona kunjalo, kutsha nje uphando , epapashwe ngo-2016, yabonisa ukuba umngcipheko wesifo sengqondo esixhalabisayo wawuphakame nje kancinci kubantu abathatha iidosi ezisezantsi ze-benzodiazepines, kwaye yayingekho kwabo bayithatha ngeedosi eziphezulu.

Uxinzelelo lokuphefumla

I-Benzodiazepines inokubangela uxinzelelo lokuphefumla, okanye i-hypoventilation, xa isetyenziselwa eyayo, kwaye nangakumbi xa idityaniswe nenye inkqubo ye-nervous system (CNS). Esi sifo sokuphefumla sibangela ukuphefumla okucothayo, okungasebenziyo, ukudala inqanaba eliphezulu le-carbon dioxide kunye nenqanaba elisezantsi leoksijini emzimbeni wakho.

I-Benzodiazepines enjengeAtivan inokubangela uxinzelelo lokuphefumla xa idityaniswe namanye amayeza okuhambisa okanye izinto ezinje ngotywala, izihlaziyisi zemisipha, ii-antihistamines, i-antipsychotic, i-anticonvulsants, kunye ne-anti-depressants. Njalo qhagamshelana nomboneleli wakho wezempilo ukuqinisekisa ukuba i-Ativan ikhuselekile ngokudibanisa namanye amayeza owathathayo.

Ukukhulelwa kunye nokuncancisa

Ukuba kunjalo ukhulelwe okanye uceba ukukhulelwa , funa ingcebiso yezonyango ngaphambi kokuba uthathe la mayeza. Izifundo zezilwanyana zibonise ukubakho kwesiqhelo kwimveku engekazalwa. Kukho umngcipheko okhulayo wokungalunganga okubangelwa kukuzola ngexesha lekota yokuqala. Ukusetyenziswa kweAtivan ngexesha lekota yesithathu kukwadityaniswa nomngcipheko okhulayo wokurhoxa kwe-neonatal. I-Lorazepam inokudlula kwiintsana kubisi lwebele kwaye inokubangela ukuba umntwana ahlaliswe kwaye abe nomsindo. Ukuba uncelisa, qhagamshelana nomboneleli wakho wezempilo.

Unxibelelwano lweAtivan

Utywala kunye neopioid kufuneka zithintelwe xa uthatha iAtivan, utshilo uGqirha Jones, Ngokubanzi, nantoni na ekwenza uzive udiniwe, kubandakanya ioyile ye-CBD kunye ne-melatonin, kufuneka ithathwe ngononophelo de ube uyazi ukuba umzimba wakho uphendula njani. Kukho amayeza aliqela anokunyusa iziphumo ezibi okanye ezinobungozi be-lorazepam. Kuhlala kulungile ukubuza usokhemesti wakho ukuba ikho into ekhuselekileyo onokuyithatha, kubandakanya amayeza, ikhawuntareni kunye namayeza e-herbal.

Ukusebenzisana kweziyobisi

Ngaphambi kokuba uthathe iAtivan, okanye nawaphi na amayeza, kuya kufuneka uxelele ugqirha wakho ngawo onke amayeza — amayeza okanye ikhawuntareni, izongezo kunye neevithamini — uthatha ikakhulu:

• IiAnticonvulsants
• Ukudakumba
• Amayeza e-asthma: theophylline
• Iyeza elibandayo
• Amayeza e-Gout: probenecid
• Amayeza esi sifo sikaParkinson: iRytary, iSinemet, kunye neStalevo (levodopa)
• Ukuphumla kwezihlunu
• Amayeza eentlungu zeOpioid
• Izinto zokubulala ngomlomo
• Izinto zokucwangcisa ngomlomo (iipilisi zolawulo lokuzalwa)
• Ukudambisa, ukuzola, okanye iipilisi zokulala
• Ukuhambisa amayeza okwehla / i-antihistamines
• Amayeza eentlungu okanye amayeza okukhohlela aqukethe ikhowudi

Ukuba uthatha naliphi na kula mayeza, ugqirha wakho unokufuna ukuhlengahlengisa idosi yakho, tshintshela kwelinye iyeza, okanye akubeke esweni ngokusondeleyo kwiziphumo ebezingalindelekanga kunye neziphumo ezibi.

Ukusebenzisana kweziyobisi

Akufanele utye iidiliya okanye imveliso yeediliya ngelixa uthatha eli yeza kuba oku kunokonyusa iziphumo kwaye kukhokelele kwityhefu okanye iimpendulo ezigwenxa.

Akufuneki usele utywala ngelixa ubuthatha njengoko unokufumana iziphumo ebezisongela ubomi.

Ngelixa kungekho zilumkiso zichasene nokusela ikofu okanye okunye ukutya kunye neziselo eziqukethe icaffeine, kubalulekile ukuba ukhumbule ukuba icaffeine iyisikhuthazi kwaye inokuthi ichase iziphumo zelorazepam.

Ungaziphepha njani iziphumo ebezingalindelekanga zeAtivan

Iziphumo ebezingalindelekanga, ezinjengokudinwa, zihlala ziqala kwakamsinya emva kokuthatha amayeza, rhoqo kwimizuzu engama-30 yokuthatha amayeza.Ngokuqhelekileyo ziyancipha njengoko iziphumo zokuncipha kweziyobisi, ngesiqhelo phakathi kweeyure ezintandathu nezisibhozo emva kokuba uyithathile. Abanye abantu bayabona ukuba iziphumo ebezingalindelekanga ziyancipha njengoko beqhubeka nokuthatha amayeza, kwaye umzimba wabo uhlengahlengisa kuwo, umzekelo, abanokuziva bediniwe emva kokuwuthatha rhoqo kangangeentsuku okanye iiveki.

1. Thatha iAtivan ngokwemiyalelo kagqirha wakho.

Ukuthatha idosi echanekileyo yeAtivanUnceda ukunciphisa imiphumo emibi onokuyifumana. Abanye abantu bayazithatha njengoko kufuneka, oko kuthetha ukuba ngamaxesha athile uziva uxhalabile, kwaye abanye babathatha rhoqo kwimini yonke ukugcina iimpawu zoxinzelelo zikhona. Ukuba ufumana iziphumo ebezingalindelekanga, thetha nogqirha wakho malunga nokuba ukutshintsha ixesha olithatha ngalo amayeza kunokunciphisa ukungonwabi kwakho.

I-Ativan ifumaneka ngeendlela ezahlukeneyo kunye namayeza:

• Inaliti ye-intramuscular: 2 mg / ml, 4 mg / ml
• Ngaphakathi: 2 mg / ml, 4 mg / ml
• Ithebhulethi yomlomo: 0.5 mg, 1 mg, 2 mg

Kuya kufuneka uqale ngedosi esezantsi kwaye usebenze kancinci ukunyuka, uqinisekisa ukuba uthatha elona dosi lisezantsi elinikezela isibonelelo kuwe. Inkqubo ye- Isalathiso seDijithali esinePrescriber (PDR) iphakamisa leedosi zilandelayo zoxinzelelo:

Umthamo we-Ativan woxinzelelo ngobudala
	Ukuqala idosi yomlomo	Ubungakanani bomthamo womlomo
Abantwana abaneminyaka eli-11 ubudala	Ukuchongwa ngeminyaka yomntwana, ubunzima, kunye nembali yezempilo.
Abafikisayo kwiminyaka eli-12 +	I-2-3 mg ngosuku yahlulwe ngeedosi ezi-2-3 yonke imihla; inokunyuka ngokuthe ngcembe njengoko kufuneka kwaye inyamezeleke	Ukuya kuthi ga kwi-10 mg ngosuku njengoko kufuneka, ukwahlulwa kube ngamayeza amaninzi (ubuninzi obuqhelekileyo obufunekayo yi-6 mg / ngosuku kwiidosi ezahluliweyo)
Abantu abadala	I-2-3 mg ngosuku yahlulwe ngeedosi ezi-2-3 yonke imihla; inokunyuka ngokuthe ngcembe njengoko kufuneka kwaye inyamezeleke	Ukuya kuthi ga kwi-10 mg ngosuku, yahlulwe yangamachiza aliqela (ubuninzi obuqhelekileyo obufunekayo yi-6 mg / ngosuku kwiidosi ezahluliweyo)
Abantu abadala beGeriatric	1-2 mg ngosuku yahlulwe amathamo 2-3 imini yonke; inokunyuka ngokuthe ngcembe njengoko kufuneka kwaye inyamezeleke	Ukuya kuthi ga kwi-6 mg ngosuku (i-2 mg ngosuku kwiindawo zononophelo lwexesha elide). Kukho umngcipheko okhulayo wetyhefu kuluntu, ke ngoko, ukunyuka okuncinci, okuthe ngcembe kungcono.

Ukuphuthelwa, idosi yabantu abadala ekhuthazwayo iqala kwi-2 mg ngexesha lokulala, inyuswe iye kwi-4 mg, ukuba iyafuneka, kunye nonyango lweenyanga ezine okanye ngaphantsi.

2. Thatha iAtivan ngokutya.

Uninzi lwabantu alunamava esisu okanye ukuphazamiseka xa usithatha iAtivan; nangona kunjalo,inokunceda ukuyithatha ngokutya.

3. Sukuyeka ngequbuliso ukuthatha iAtivan.

Iimpawu zokurhoxa kwi-Ativan zinokungonwabi ngakumbi kuneziphumo ebezingalindelekanga.Akufanele uyeke ukuthatha amayeza ngequbuliso, ngakumbi ukuba uwathatha rhoqo.Iimpawu zokurhoxa zibandakanya ukuxhalaba, ukungazinzi, ukuthuthumela, ukubila, ukuphazamiseka, ukulala, kunye nokuhlaselwa. Ezi mpawu ziqala kwintsuku ezimbini ukuya kwezimbini emva kwethamo lakho lokugqibela kwaye zinokuhlala iintsuku ezisixhenxe okanye nangaphezulu, kuxhomekeke ekubeni uthathe ixesha elingakanani. Kungcono uku-taper ukuba ungakanani kwaye uyithatha kancinci kangakanani.

Ugqirha wakho uya kusebenza kunye nawe ukuseta ishedyuli yokukhusela ngokukhuselekileyo. Inkqubo ye- ISebe lezeMpilo laseSan Mateo icebisa ngeendlela ezimbini zokuthinta:

• Ukuncitshiswa kwe-25% yedosi yokuqala rhoqo kwiiveki ezimbini, okanye
• Ukunciphisa idosi nge-25% kwiveki yokuqala, iipesenti ezingama-25 kwiveki yesibini, emva koko nge-10% veki nganye de uyeke iyeza

Inkqubo yokuthinta inokuthatha iiveki ezimbalwa ukuya kwiinyanga ezimbalwa ukuyeka ngokupheleleyo amayeza. Ukwenza ngale ndlela kushenxisa okanye kunciphisa ngokumangalisayo naziphi na iimpawu zokurhoxa ohlangabezana nazo.

4. Buza ugqirha wakho ngokutshintshela kwelinye iyeza.

Umboneleli wakho wezempilo unokucebisaukuzama amanye amayeza oxinzelelo endaweni yeAtivan. Abanye iziyobisi inokunciphisa iimpawu zoxinzelelo. Oku kubandakanya:

• ICymbalta (duloxetine)
• Silenor (Doxepin)
• ILexapro (isitalitalopram)
• Paxil , IPaxil CR , Pexeva , IBrisdelle (paroxetine)
• I-Effexor XR (venlafaxine)

Kukho nezinye i-benzodiazepines, ezibandakanya:

• Xanax (alprazolam)
• Valium (diazepam)
• IKlonopin (clonazepam)

Wonke umntu usabela kumayeza ngokwahlukileyo. Okona kusebenza kakuhle komnye umntu kunokungasebenzi komnye. Kungcono ukusebenza ngokusondeleyo nogqirha wakho kwaye ufunde ngazo zonke iindlela zonyango onokuthi ukhethe kuzo ukuze ufumane ichiza elisebenza ngcono kuwe.