Eyona >> Ulwazi Lweziyobisi >> Iziphumo ebezingalindelekanga zeMetronidazole kunye nendlela yokuzikhusela

Iziphumo ebezingalindelekanga zeMetronidazole kunye nendlela yokuzikhusela

Ulwazi lweziyobisi iMetronidazole yintsholongwane esetyenziselwa ukunqanda ukukhula kwezifo ezithile ezibangelwa ziintsholongwane. I-Metronidazole ithengiswa phantsi kwegama lophawu lweFlagyl kunye neFlagyl ER.

Iziphumo ebezingalindelekanga zeMetronidazole kunye nendlela yokuzikhusela

I-Metronidazole yintsholongwane esetyenziselwa ukunqanda ukukhula kwezinye iintsholongwane kunye nosulelo lweparasitic kubandakanya ulusu, vaginosis yebhaktiriya (BV), itrichomoniasis , kunye nesifo sokudumba kwepelevic (PID). Ingasetyenziselwa ukunyanga ithumba. I-Metronidazole ithengiswa phantsi kwegama lophawu lweFlagyl kunye neFlagyl ER (ukukhutshwa okwandisiweyo). Inokuza njengeyeza lomlomo, ijeli yelungu lobufazi, ukhilimu, okanye into yokuthambisa. Kukho uhlobo lwe-IV lwe-metronidazole ukuba abanye abaqeqeshi bezempilo baya kuyisebenzisa kwisibhedlele.

Kukho iziphumo ebezingalindelekanga eziqhelekileyo kubandakanya intloko ebuhlungu, ukucofa, kunye nesicaphucaphu. Ngokubanzi, zimbalwa iziphumo ebezingalindelekanga kunyango lwasekhaya nakwindlela yelungu lobufazi. Ukusebenzisana kweziyobisi kunokwenzeka xa kusenziwa i-metronidazole, ke kubalulekile ukuba uqonde umngcipheko ngaphambi kokuqala unyango.

Ezinxulumene: Funda ngakumbi malunga ne-metronidazole

Iziphumo eziqhelekileyo ezichaphazelekayo zomlomo we-metronidazole

Iziphumo eziqhelekileyo ezichaphazela iipilisi ze-metronidazole kunye neepilisi njenge:

Isicaphucaphu nokugabha
Intloko ebuhlungu
Ukuphelelwa ngumdla wokutya
Urhudo
Intlungu yesisu okanye ukubamba
Ubumhlophe obukhanyayo okanye isiyezi
Ukuqunjelwa
Umlomo owomileyo
I-Metallic incasa emlonyeni
Irhashalala
Ukudumba komlomo, imilebe, okanye ulwimi
Umchamo omnyama (umbala obomvu / omdaka)
Isifo segwele

Isihlunu kunye nesifo sohudo

Isicaphucaphu kunye norhudo ziziphumo ebezingalindelekanga eziqhelekileyo kwimetronidazole. Ngokwe- Ulawulo lweeDrug , malunga neepesenti ezili-12 zezigulane ezithatha iipilisi ze-metronidazole zichaza ukuba nazo zine-nausea, ngamanye amaxesha ehamba kunye nehudo. Amacwecwe e-Metronidazole anokuthathwa kunye nokutya okufana nesidlo okanye ukutya okulula ukunceda ukunciphisa isisu. Nangona kunjalo, uguqulelo olwandisiweyo lwe-metronidazole kufuneka luthathwe kwisisu esingenalutho okungenani iyure enye ngaphambi kokutya okanye ubuncinci iiyure ezimbini emva kokutya.

Ukuba iziphumo ebezingalindelekanga zamathumbu zixhalabisile, abantu banokumiselwa ngendlela engundaba-mlonyeni okanye yelungu lobufazi lwe-metronidazole ukuba kufanelekile kuhlobo losulelo. Ezi ntlobo ze-metronidazole have mancinci amathuba okubangela isicaphucaphu kunye norhudo .

Iziphumo eziqhelekileyo ezichaphazelekayo ze-metronidazole

Iziphumo eziqhelekileyo ezichaphazelekayo ze-metronidazole yelungu lobufazi, ukhilimu kunye ne-lotion zibandakanya:

Ukucaphuka kolusu kubandakanya ukoma kancinci okanye ukutsha
Ukurhawuzelela
Isicaphucaphu
I-Metallic incasa emlonyeni
Intloko (ijel lobufazi kuphela)
Ukukhutshwa kwilungu lobufazi (ijeli yelungu lobufazi kuphela)
Usulelo lwegwele (ijeli yelungu lobufazi kuphela)

Usulelo lwegwele

I-Metronidazole akufuneki isetyenziselwe ukunyanga usulelo lwegwele (isifo segwele). Ngapha koko, ukusetyenziswa kwe-metronidazole kunokubangela usulelo lwegwele kwezinye. Kuqikelelwa ukuba I-10% yabasetyhini ukuthatha i-metronidazole iphelela kusulelo lwegwele njengesiphumo sonyango.

Ngelixa i-metronidazole iyasebenza ekupheliseni iibhaktheriya ezimbi ezibangela usulelo, inokuthi itshabalalise neebhaktiriya eziluncedo zihlala zihlala kwilungu lobufazi. Oku kunokukhokelela kuphazamiseko kwindalo yelungu lobufazi kunye nokugcwala kwegwele.

Kubafazi abasoloko befumana usulelo lwegwele xa besebenzisa amayeza okubulala iintsholongwane, ugqirha wabo unokubanikezela ngokufanelekileyo amayeza okubulala I-Diflucan (i-fluconazole) .

Iziphumo ebezingalindelekanga ezimandundu zemetronidazole yomlomo

Iziphumo ebezingalindelekanga ezimandundu zeepilisi ze-metronidazole kunye neepilisi njenge:

Ukuxhuzula
Ukudumba kwenwebu yengqondo
I-peripheral neuropathy
Ukonakala kwimbilini ye-optic
Umonakalo wobuchopho
I-Anaphylaxis (isifo esibi kakhulu esivelisa ukuvelisa imihlathi kunye nokudumba kobuso kunye nomqala)
Isifo i-Stevens-Johnson syndrome (isifo esenziwe ngamayeza esibangela iimpawu ezinje ngomkhuhlane kunye nerhashalala elibuhlungu)
I-epidermal necrolysis enetyhefu (imeko enqabileyo kodwa enzima yesikhumba ebangela ukudumba nokuxobuka)
Amaseli egazi amhlophe asezantsi
Iiplatelets ezisezantsi
I-Neutropenia (i-neutrophils ephantsi)
Ipancreatitis (ukudumba kwepancreas)
Ixesha elide le-QT (ukuphazamiseka kwimisebenzi yentliziyo ngakumbi xa kuthathwa namanye amayeza ayolula ixesha le-QT)

Zithatha ixesha elingakanani iziphumo ebezingalindelekanga zemetronidazole?

Iziphumo eziqhelekileyo ezichaphazelekayo ze-metronidazole ziya kuphucula ngokukhawuleza xa unyango lugqityiwe. Kuxhomekeka kuhlobo losulelo, abantu banokusebenzisa i-metronidazole usuku olunye kuphela okanye ukuya kwiintsuku ezili-14. Ukuba kukho urhudo okanye ukugabha okungathethekiyo, umboneleli wezempilo unokumtshintshela umntu kwelinye iyeza.

Ezinye iziphumo ebezingalindelekanga ezibi zinokufuna ukuba umntu ayeke unyango nge-metronidazole. Ukuphikisa komzimba kunye ne-metronidazole kunqabile, kodwa kunokwenzeka. Abantu kufuneka banxibelelane nogqirha wabo kwaye bayeke ukusebenzisa kwangoko xa befumana naziphi na iimpawu zempendulo ebukhali kubandakanya umngxunya, ukungaphefumli kakuhle, ukurhawuzelela okukhulu, okanye ukudumba kobuso okanye umqala.

Izimo kunye nezilumkiso zeMetronidazole

I-Metronidazole isenokungabi lolona nyango lufanelekileyo kuwo wonke umntu. Abanye abantu banokuba novakalelo ngakumbi kwimetronidazole, besenza ezinye iindlela zamachiza ukuba zilunge ngakumbi. Ukuba abantu babenempendulo engalunganga xa babethatha i-metronidazole kwixa elidlulileyo, kufuneka baqinisekise ukuxelela umboneleli wezempilo. Kuya kufuneka baxoxe ngokuthatha i-antibiotiki eyahlukileyo ukunqanda enye impendulo.

Ngethamsanqa, i-metronidazole ayenzi ukuxhomekeka. Iidosi eziphezulu zeliyeza zinokubangela isicaphucaphu kunye nokugabha, kunye nokuswela ukulungelelaniswa kwemisipha (ataxia). Ukuba kulindelwe ukubanda ngaphezulu, abantu kufuneka babize ulawulo lwetyhefu lwasekhaya okanye baye kwigumbi likaxakeka ukuze bavavanywe.

Isifo sesibindi

Ukuba umntu unesifo sesibindi, i-metronidazole isenokungabi lolona khetho lonyango lufanelekileyo. Ngenxa yokuba i-metronidazole iqhutywa esibindini, inokukhokelela kumngcipheko okhulayo wetyhefu esibindini. Ngaphandle komngcipheko, abantu abanesifo sesibindi banokukwazi ukuthatha ngokukhuselekileyo i-metronidazole. Ababoneleli ngezempilo baya kuba nakho ukufumanisa ukuba ngaba isigulana sabo kufuneka sikuphephe ukuthatha i-metronidazole.

Ukuxhuzula

I-Metronidazole lelinye lamayeza anokunciphisa umqobo wokubanjwa. Oku kuthetha ukuba umntu kunokwenzeka ukuba abambe xa ethatha eli chiza. Abantu abanembali yokuxhuzula okanye ukuxhuzula kufuneka bafumane iingcebiso zonyango kumboneleli wezempilo ngaphambi kokuba bathathe eli chiza. Ukuba unyango ngeli chiza lisafuneka, amanyathelo okhuseleko ongezelelweyo kufuneka abekwe endaweni.

Iingxaki ze-CNS

Metronidazole kunokubangela peripheral neuropathy. Oku kuthetha ukuba umntu unokufumana ubuthathaka, ukuba ndindisholo, okanye iintlungu ezandleni nasezinyaweni. Abantu abane-CNS (inkqubo ye-nervous system) ukuphazamiseka kufuneka basebenzise isilumkiso xa besebenzisa eli yeza. Jonga imiqondiso ye-ataxia kubandakanya intetho egudileyo, ukuhamba nzima, ukuwa, okanye eminye imiba yokulungelelanisa.

Ukuphazamiseka kwegazi

Impembelelo embi ye-metronidazole ibandakanya ukubalwa kweeseli eziphantsi kwegazi. Ngesi sizathu, abaguli abaneeseli zegazi ezingaqhelekanga banokufuna ukubekwa esweni ngokusondeleyo ngexesha lonyango lwe-metronidazole. Ababoneleli ngezeMpilo banokufuna ukwenza iseti elula yomsebenzi waselebhu ngaphambi kokuqala unyango.

Isifo seCockayne

Abantu abane-Cockayne syndrome, isifo esinqabileyo esibangela ukuguga ngaphambi kwexesha, intloko encinci ngokungaqhelekanga, kunye nokukhula kunye nokulibaziseka kokufunda, akufuneki bathathe i-metronidazole. Iyeza kunokubangela umngcipheko ukwanda ukusilela kwesibindi. Nangona kunjalo, ukuba ababoneleli ngezempilo bakholelwa ukuba i-metronidazole iyimfuneko, banokufuna ukukhangela ukusebenza kwesibindi ngaphambi nasemva konyango. Jonga le miqondiso ilandelayo yomonakalo wesibindi ngelixa uthatha eli yeza:

Ukuthungwa kwesikhumba okanye amehlo (i-jaundice)
Iintlungu zesisu esisekunene
Ukudumba kwesisu
Isihlunu kunye / okanye ukugabha

I-Metronidazole ngelixa ukhulelwe

I-Metronidazole yicandelo B lokukhulelwa le-FDA kwaye livunyiwe ukuba lisetyenziswe ngexesha lokukhulelwa. Oku kuthetha ukuba izifundo zezilwanyana azibonisi monakalo kwimveku engekazalwa, kodwa izifundo zabantu zisafuneka ukumisela umngcipheko. Kukho idatha encinci ukubonisa umngcipheko weziphene zokuzalwa okanye ukuphuphuma kwesisu xa uthatha i-metronidazole ngexesha lokukhulelwa.

I-Metronidazole akufuneki isetyenziselwe i-trichomoniasis, i-STI (isifo esosulela ngokwabelana ngesondo), kwikota yokuqala. Usulelo lwe-trichomoniasis olunganyangekiyo lunokwandisa ithuba lokuhanjiswa kwangaphambi kwexesha. Kukho umngcipheko okhulayo wosana olunesisindo sokuzalwa esisezantsi. Ukuba umama unesifo esosulelayo, unokuhambisa usana ngexesha lokuhanjiswa kwelungu lobufazi.

I-Metronidazole ngelixa uncancisa

Nangona I-metronidazole inokumiselwa ngelixa uncancisa, inokuhamba iye kubisi lwebele. Ingabangela urhudo kunye / okanye i-oral thrush kusana. Ukuba umiselwe idosi enkulu ye-metronidazole, umama kufuneka acinge ngokumpompa nokulahla ubisi lwakhe ngalo lonke ixesha lokunyanga kunye neeyure ezingama-24 ezongezelelweyo emva kokumisa i-metronidazole.

Metronidazole kunye nabantwana

Metronidazole ivunyiwe ukuba isetyenziswe ebantwaneni. Abantwana banokuthatha i-metronidazole kusulelo oluthile kubandakanya i-amebiasis, trichomoniasis, C usulelo olwahlukileyo (C diff.), Okanye H. pylori. Ukuba umntwana unembali yezintso okanye iingxaki zesibindi, umboneleli wezempilo unokuthatha isigqibo sokunciphisa idosi kwisiqingatha.

Ukudibana kweMetronidazole

Kukho iindlela ezimbalwa zokunxibelelana kweziyobisi xa uthatha i-metronidazole. Abantu kufuneka baqiniseke ukuba baxelele ugqirha ukuba bathini amayeza ngaphambi kokuba baqale unyango.

Olunye unxibelelwano olunokubakho lubandakanya:

Disulfiram: Idisulfiram , ichiza elisetyenziselwa ukubuyisa utywala, linokuphendula nge-metronidazole ukwenza impendulo yengqondo. Le mpendulo imbi inokubandakanya ukudideka, ukubona izinto ezingekhoyo, okanye ukukhohlisa. Gwema ukuthatha i-disulfiram ubuncinci iiveki ezimbini ngaphambi kokuqala kwe-metronidazole.
Abacoci begazi: Sebenzisa isilumkiso xa uthatha i-metronidazole enegazi, njenge-warfarin. Ukuthatha la mayeza kunye kunokubangela ukuba umntu aphume igazi ngokulula. I-PT yomntu kunye ne-INR kusenokufuneka ihlolwe ngaphambi nangexesha lonyango ukuze idosi ye-warfarin ilungelelaniswe ngokufanelekileyo.
Lithium: I-Metronidazole inokusebenzisana nendlela i-lithium isuswe ngayo emzimbeni, ekhokelela kwiziphumo ezinobungozi.
Busulfan: I-Metronidazole kufuneka ithintelwe kunyango lwe-chemotherapy, busulfan. I-Metronidazole inokunyusa inani le-busulfan emzimbeni kwaye ikhokelele kwixabiso elinetyhefu.
Utywala: Abantu akufuneki basele utywala xa bethatha i-metronidazole. Oku kunxibelelana kubangela isicaphucaphu esiqatha, ukugabha, ukugungxula, isiyezi, intloko ebuhlungu, kunye neempawu eziqhelekileyo zokungaphili. Ukongeza kwiziselo ezinxilisayo, abantu kufuneka baziphephe ezinye iimveliso ezinokuba notywala. Amanye amayeza kunye neemveliso zokutya ziqulathe utywala okanye ipropylene glycol. Isithako sepropylene glycol sisihlanganisi sokutya esidityanisiweyo esidityanelweyo kusapho lotywala, kungoko ke kufanelekile ukunqanda oku ngokunjalo. Kubalulekile ukuba uxoxe nangawaphi na amayeza kunye noogqirha ngaphambi kokuthatha i-metronidazole.

Ungaziphepha njani iziphumo ebezingalindelekanga zeMetronidazole

I-Metronidazole isenokungakulungeli wonke umntu, ke kubalulekile ukuba uxoxe ngamayeza kunye nomboneleli wezempilo ngaphambi kokuba uqale unyango. Ezinye iziphumo ebezingalindelekanga zingenza unyango nge-metronidazole lungakhululeki, kodwa kukho iindlela zokuthintela okanye ukunciphisa ezi ziphumo ebezingalindelekanga kunye nokwenza unyango lunyamezeleke.

Ezinye iindlela zokuthintela ukusabela okungalunganga xa uthatha i-metronidazole zibandakanya:

1. Thatha i-metronidazole njengoko kuyalelwe

Abantu kufuneka balandele izikhokelo zabo zononophelo lwempilo xa bethatha i-metronidazole. Umthamo kunye nonyango luxhomekeke koluphi usulelo oluphathwayo. Kuba i-metronidazole ifumaneka ngeendlela ezahlukeneyo, ugqirha unokuyalela ukwenziwa kwentloko okanye ubufazi ukunceda ukunciphisa iziphumo ebezingalindelekanga ukuba kufanelekile kuhlobo losulelo. Ababoneleli ngezeMpilo banokumisela idosi kube kanye amaxesha ambalwa ngemini, okanye idosi yexesha elinye. Kubalulekile ukuba ufunde ngolwazi lweziyobisi olunikezelwa yikhemesti xa ukhetha amayeza.

2. Thatha i-metronidazole ngokutya

I-metronidazole yomlomo inokubangela isisu esibuhlungu, okanye ukugabha. Iziphumo ebezingalindelekanga zihlala zisiba mbi xa uthatha iipilisi ze-metronidazole okanye iipilisi njengento engenanto esiswini. Ngaphandle kokuba i-metronidazole ikhutshiwe-ukukhutshwa, iidosi zokumatanisa kunye nesidlo okanye ukutya okutyayo kuya kunceda ukuthintela ezi mpembelelo zibi ukuba zingenzeki okanye zibe nzima.

3. Kunqande utywala kunye neemveliso ezinotywala xa uthatha i-metronidazole

Utywala kunye ne-metronidazole akufuneki zixutywe kuba zinokubangela ukwanda kweziphumo ebezingalindelekanga. Abantu kufuneka bayeke ukusela utywala ngexesha lonyango kwaye kwiintsuku ezintathu emva kokugqiba unyango ukuqinisekisa ukuba abayi kuba neziphumo ezibi. Amayeza ambalwa aqukethe utywala aquka iNyquil, iRobitussin, kunye neVicks Cough. Ukufumanisa ukuba amayeza e-e-okteshini aqukethe utywala, funda iilebheli zezithako kwibhotile yamayeza okanye ebhokisini.

4. Gqiba yonke irejimeni yonyango

Ungayeki ukuthatha i-metronidazole phambi kokuba unyango lugqitywe, nokuba iimpawu zakho ziphelile. Kuqhelekile ukuba abantu baqale ukuziva bhetele kwangoko kwikhosi yabo yonyango, ke kubalulekile ukuba ukhumbule ukugqiba ikhosi yonke yonyango. Ukungalugqibi unyango lwe -antibiotic kunokubangela ukuxhathisa, nako oko, kwenza ukuba ichiza lingasebenzi kakuhle. Kubalulekile ukuthatha i-metronidazole kanye ngendlela umboneleli wezempilo ayimisele ngayo.

5. Yandisa imilinganiselo ngokulinganayo imini yonke

Iidosi ze-metronidazole kufuneka zisasazwe ngokulinganayo imini yonke xa kumiselwe iidosi ezininzi. Ukuba abantu bayaphoswa yidosi, kuya kufuneka bathathe idosi ephosiweyo kwangoko bakhumbula. Kubalulekile ukuba ungathathi idosi ezimbini ngaxeshanye. Ukuba abantu banengxaki yokukhumbula ukuthatha amayeza abo, banokufuna ukuseta ixesha njengesikhumbuzo okanye basebenzise ibhokisi yeepilisi ngexesha lonyango lwabo.

6.Thetha ugqirha malunga nawo onke amayeza ngaphambi kokuqala unyango kunye ne-metronidazole

Amanye amayeza anokusebenzisana ne-metronidazole, ke kubalulekile ukuba abantu baxoxe ngayo nayiphi na imigqaliselo abayithathayo nogqirha wabo, kunye ne-over-counter-counter kunye ne-herbal supplements. Ugqirha uya kugqiba ukuba kukho umngcipheko wokunxibelelana kweziyobisi ngexesha lonyango. Ukuba unxibelelwano lunokwenzeka, ugqirha unokuthatha isigqibo sokunyanga elinye iyeza.

7. Kunqande ukwabelana ngesondo ukuba uthatha i-metronidazole ye-trichomoniasis

I-Trichomoniasis sisifo esidluliselwa ngeentlobano zesini, oko kuthetha ukuba abantu bosulelekile ngenxa yokulala nomntu owonayo. I-Metronidazole liyeza eliqhelekileyo elisetyenziselwa ukunyanga esi sifo. Ukuba umntu uphathwa i-trichomoniasis, amaqabane abo anokufuna ukunyangwa. Oku kuthintela abantu ekubeni bosuleleke emva kokuba unyango lugqityiwe. Kunqabe ukuba neentlobano zesini de ugqibe ikhosi ye-antibiotics kwaye unikwe imvume yingcali yezempilo. Kwakhona kubalulekile ukuthintela ukulala ngesondo xa usebenzisa ijeli yelungu lobufazi le-metronidazole.

7.Thatha iprobiotic

Sebenzisa iprobiotic ngelixa uthatha unyango lonyango ezinjenge-metronidazole yomlomo zinokunceda ukunciphisa iziphumo ebezingalindelekanga ezinje ngesisu kunye nesifo sohudo. Iiprobiotic zinokunceda ukongeza amathumbu ngeebhaktheriya ezilungileyo ezinokuthi zonakaliswe yintsholongwane. Kubalulekile ukwahlula idosi yokubulala iintsholongwane kwidosi yeprobiotic ubuncinci iiyure ezi-2. Iiprobiotic ziyafumaneka ukuze zithengwe ezikhemesti nakwiivenkile zokutya.