Yintoni iToradol kwaye isetyenziselwa ntoni?

Ulwazi lweziyobisi

Ugqirha unokukunika iToradol (ketorolac) kwigumbi likaxakeka ngenxa yeentlungu eziqatha, njenge-migraine enzima. Okanye, ugqirha unokumisela i-analgesic emva kotyando. Ukuba awukayithathi kwindawo yesibhedlele, unokukhumbula iToradol ukusuka 2011 ityala etyhola ukuba i-NFL ilawula i-painkiller kubadlali ngaphambi nangexesha lemidlalo yebhola ekhatywayo. Sisisiyobisi esinamandla sokuthomalalisa iintlungu, kodwa ngenxa yeziphumo ebezingalindelekanga, iToradol ikhuselekile kuphela ekusebenziseni ixesha elifutshane.

Yintoni iToradol?

I-Toradol yonyango elichasene ne-anti-inflammatory drug ( NSAID ) yenziwe nguPfizer Pharmaceuticals. Eli chiza linegama iqulethe ketorolac tromethamine. Iyanyanga ngokuphakathi ukuya kubuhlungu obukhulu ngokunciphisa i-prostaglandins, iihomoni ezibangela ukudumba, umkhuhlane kunye nentlungu. Ayisiyo narcotic kwaye ayizikhobokisi; Nangona kunjalo, yamkelwe kuphela ukuba isetyenziswe kangangeentsuku ezintlanu okanye ngaphantsi.

Isebenziselwa ntoni iToradol?

I-Toradol yintlungu engeyiyo-opioid yokunciphisa intlungu yokumodareyitha kwiintlungu ezinzima. Isetyenziselwa ulawulo lwentlungu ngaphambi okanye emva kweenkqubo zonyango ezinje ngokuhlinzwa, ukuvumela ukuba ubuyele kwimisebenzi yakho yemihla ngemihla ngokukhawuleza.

Ukusetyenziswa okuqhelekileyo kweToradol kukukhulula iintlungu emva kokuhlinzwa. Idosi yakho yokuqala itofelwe okanye ilawulwa nge-IV. Iipilisi zeToradol zinokumiselwa ukuba uthathe ngomlomo ekhaya.

I-Toradol ikwasetyenziselwa:

• Iingxaki zeseli zokugula
• Amatye eentso
• Intlungu ebuyela emva
• I-migraine efanelekileyo okanye intloko ebuhlungu

I-Toradol sisiyobisi esinamandla esinokuthomalalisa iintlungu ezilinganiselweyo kunye nobunzima kwixesha elifutshane. Unokuziva iziphumo ngokukhawuleza kwimizuzu eli-15 emva kokufumana inaliti. Ayinakunyanga iintlungu ezingapheliyo, ezinjengesifo samathambo, kuba kukho iziphumo ebezingalindelekanga ezimandundu. Yonyusa umngcipheko wokuhlaselwa sisifo sentliziyo kunye nokubetha kwaye kunokubangela ukusilela kwezintso xa kuthathwe ixesha elingaphezu kweentsuku ezintlanu.

Ngaba ufuna elona xabiso lilungileyo kwiToradol?

Bhalisela izilumkiso zamaxabiso eToradol kwaye ufumane ukuba amaxabiso atshintsha nini!

Fumana izilumkiso zamaxabiso

Imilinganiselo yeToradol

I-Toradol ifumaneka njenge-injection, nge-IV, njenge-spray spray, kunye neepilisi. Umthamo wokuqala womntu omdala (ngaphezulu kweepawundi ezili-110) ngama-60 mg njengenaliti okanye i-30 mg efakwe ngaphakathi Ulawulo lwezoKutya kunye noLawulo lweziyobisi (FDA). Amanqanaba ongezelelweyo anokunikwa rhoqo kwiiyure ezintandathu, njengoko kufuneka, ukuya kuthi ga kwi-120 mg / ngosuku. Kulabo bangaphantsi kweepawundi ezili-100, idosi iyanqunyulwa kwisiqingatha. Umthamo wokutshiza ngeempumlo yenye yokutshiza kwikhala ngalinye kwiyure ezintandathu ukuya kwezisibhozo, njengoko kufuneka njalo.

Amacwecwe enzelwe unyango olulandelayo kuphela. Kubantu abadala, idosi eqhelekileyo yi-20 mg ukuqala kwaye emva koko i-10 mg qho kwiiyure ezine ukuya kwezintandathu. Kulabo bangaphantsi kweepawundi ezili-110, idosi iguqula i-10 mg ilandelwe yi-10 mg rhoqo kwiiyure ezine ukuya kwezintandathu njengoko kufuneka. Kubantu abadala abadala, sebenzisa i-dosing kubantu abadala abangaphantsi kweepawundi ezili-110. Kuya kufuneka uyeke amayeza kwiintsuku ezintlanu emva kwethamo lokuqala.

Ukuba uyaphoswa yidosi, ungathatha idosi ephosiweyo xa uyiqonda, ukuba nje inde kunedosi ebekiweyo. Umzekelo, ukuba amayeza akho abonisa zonke iiyure ezine ukuya kwezintandathu, ungathatha idosi ephosiweyo ukuba ingaphezulu kweeyure ezine ukusukela kwidosi yakho yokugqibela. Kuya kufuneka ukuba unqume ixesha lokuthatha idosi elandelayo ngokuya ugqibe ukuthatha amayeza, hayi ishedyuli yakho yoqobo.

Sebenzisa eli chiza njengoko kumiselwe ixesha elifutshane kuphela. Ngenxa yokuba yi-NSAID, ukuphuma kwegazi kungumphumo weToradol. Uninzi lwababoneleli bezempilo baya kunciphisa ukusetyenziswa kweToradol kwiintsuku ezintlanu kuphela zentlungu ebukhali. Emva kweentsuku ezintlanu, ugqirha uya kuthi acebise ukutshintshela kwelinye iyeza ukuze ukhulule iintlungu.

Izilumkiso kunye nezilumkiso

Izithintelo zobudala

I-Toradol ayivunyelwanga abantwana abangaphantsi kweminyaka emibini kwaye ukhuseleko lwayo alwaziwa kwizigulana ezingaphantsi kweminyaka eyi-17. Izigulana ezingaphezulu kweminyaka engama-65 ubudala ziyacetyiswa ukuba zingasebenzisi iToradol.

Ukukhulelwa kunye nokuncancisa

Kuya kufuneka uxelele ugqirha wakho ukuba ukhulelwe, uncancisa, okanye ucwangcisa ukukhulelwa ngaphambi kokuba uthathe iToradol. Ukuyithatha ngexesha lokugqibela lokukhulelwa kunokulimaza umntwana wakho ongakazalwa, ngokwe-FDA.

I-Toradol ludidi lokukhulelwa lwe-FDA C, okuthetha ukuba izifundo kwizilwanyana zibonise iziphumo ezibi kwaye akukho zifundo zilawulwayo kwabasetyhini abakhulelweyo. Iziyobisi kufuneka zinikwe kuphela ukuba isibonelelo esinokubakho siqinisekisa ubungozi obunokubakho kwimveku engekazalwa, uyacacisa UFeng Chang , Pharm.D., Kunye noprofesa onxulumene nabo kwiYunivesithi yaseWaterloo's School of Pharmacy. Imingcipheko enokubakho ibandakanya ukwanda komngcipheko wokuphuma kwesisu, ukwanda komngcipheko wokuvalwa ngaphambi kwexesha kwe-ductus arteriosus. Idatha yezilwanyana ibonakalise ukulibaziseka kwesahlulo kunye nomngcipheko owandayo wokuzalwa kwakhona.

Izigulana ezithatha inaliti okanye ngomlomo iToradol kufuneka ziyeke ukuncancisa okanye zifune amanye amayeza. Nangona kunjalo, isitshizi sempumlo se-ketorolac sinokuthathwa njengehambelana nokuncancisa ngokwe IAmerican Academy yeZilwanyana . I-Ketorolac iyakhutshwa kubisi lomntu kodwa [akukho] mbonakaliso icacileyo yeziphumo ezibi kwiintsana ezincancisayo, utshilo uGqirha Chang.

Unxibelelwano lweToradol

Kuya kufuneka uqiniseke ukuba ugqirha wakho uyazi onke amayeza owathathayo ukunqanda ukuhlangana gwenxa kweziyobisi. Musa ukuthatha iToradol ukuba uthatha:

• IPentoxifylline
• Iiprobene
• ILithium
• Imethotrexate
• Abacoci begazi
• Amayeza antipsychotic
• Intliziyo okanye uxinzelelo lwegazi amayeza
• Ukuphumla kwezihlunu
• Amayeza okuhlutha
• IiSteroids, ezinje nge-prednisone

Kuya kufuneka uphephe ukusela utywala kunye nokuthatha ezinye ii-NSAID, ezinje ngeasprini, ibuprofen, naproxen, celecoxib, diclofenac, indomethacin, kunye ne-meloxicam. Ukuthatha kakhulu kuyo nayiphi na i-NSAID kunokubangela izilonda kunye nokuphuma kwesisu, ngokwe Ulawulo lweTyhefu . Idosi enkulu inokwenzakalisa izintso kwaye inokubangela ukuxhuzula kunye nokudinwa. Funa iingcebiso zonyango okanye unxibelelane noLawulo lweTyhefu ukuba ngempazamo uthathe i-NSAID engaphezulu kwe-counter xa uthatha iToradol.

Kuya kufuneka uphephe ukusetyenziswa kotywala ngelixa uthatha i-ketorolac njengoko inokwandisa amathuba okuphuma kwesisu.

Indlela yokuphila okanye izithintelo emsebenzini

Eli chiza linokubangela isiyezi okanye ukozela kwaye linokuphazamisa ukubanakho ukuqhuba okanye ukusebenzisa oomatshini ngokwe Ilayibrari yeSizwe yezeMpilo yaseMelika . Kuya kufuneka uyeke ukwenza le misebenzi de ube uyazi ukuba lichaphazela njani na iyeza.

Zithini iziphumo zecala leToradol?

I-Toradol yamkelwe yi I-FDA ukulungelelanisa ukuya kwiintlungu ezinzima kwaye kukhuselekile xa kuthathwa njengoko kuyalelwe. Ukuyithatha kungonyusa ithuba lakho lokuhlaselwa sisifo sentliziyo okanye ukubetha. Ukuba unesifo sentliziyo, uxinzelelo lwegazi oluphezulu, i-cholesterol ephezulu, okanye isifo seswekile, kuya kufuneka uxelele ugqirha ngaphambi kokuba uthathe eli yeza. Iziphumo eziqhelekileyo ezichaphazelekayo zeToradol ziquka:

• Isihlunu, isisu esicasulayo, ukunyanzelisa, okanye ukuguquka kwentliziyo
• Urhudo
• Ukuba nesiyezi
• Ukozela
• Intloko ebuhlungu
• Ukudumba
• Ukutyeba kwakho

Abanye abantu banoluvo olugqithisileyo lwentlalo-ntle okanye uvuyo kweli yeza.

Kukho ezinye iziphumo ezibi kakhulu. Ukuba ufumana iimpawu zolu hlobo lulandelayo, kufuneka ufune unyango ngokukhawuleza.

• Ukopha esiswini: Izitulo ezinegazi okanye zokulinda, ukukhohlela igazi, ukugabha okufana nekofu
• Iingxaki zezintso kunye nomngcipheko okhulayo wokuba nesifo sezintso: Ukunciphisa ukuchama, ukuchama okunzima okanye okubuhlungu, ukudumba iinyawo zakho kunye namaqatha, ukuziva udiniwe kunye nokuphefumla okufutshane
• Anemia: Isikhumba esimdaka, ukuziva unentloko engenamphunga okanye ukuphefumla okufutshane, ukubetha kwentliziyo okukhawulezayo, ingxaki yokujonga
• Iingxaki zesibindi kunye nomngcipheko okhulayo wokufumana isifo sesibindi: Isicaphucaphu, iintlungu esiswini esingaphezulu, ukozela, ukurhawuzelela, ukuphelelwa ngumdla wokutya, umchamo omnyama, iimpawu ezinjengomkhuhlane, ubumthubi besikhumba namehlo
• Stroke: Ukuba ndindisholo kwelinye icala lomzimba, ubuthathaka, nokuphefumla kancinci

Ngaba zikhona ezinye iindlela zokwenza iToradol?

Ezinye ii-NSAID ziyafumaneka kwi-counter, njenge-ibuprofen (Advil, Motrin), naproxen (Aleve), kunye ne-aspirin. Ngaphandle kweToradol, kukho ezinye iziyobisi ezichongiweyo ezithomalalisa iintlungu ezinesifo samathambo, tendinitis, iintlungu emva kokubeleka kunye nezinye izinto. Ezi zonyango zibandakanya:

• ICelebrex (celecoxib)
• Lodine (etodolac)
• Nalfon (fenoprofen)
• Ummiselo ibuprofen
• Indocin (indomethacin)
• IPonstel (mefenamic acid)
• Imobic (meloxicam)
• UNabumetone
• I-Daypro (oxaprozin)
• UFeldene (piroxicam)
• Iklinikhi (sulindac)
• Tolectin (itolmetin)

Ii-NSAID ze-Prescription zinamandla okuphelisa iintlungu. Ngamanye amaxesha badidekile neziyobisi, ezinje yere . Intlungu ye-narcotic iyaphelisa , ikwabizwa ngokuba kukuphelisa iintlungu ze-opioid, kufuneka isetyenziselwe kuphela ukunyanga iintlungu ezingancedwa ngamanye amayeza okuphelisa iintlungu. Ungasebenzisa iintlungu zokuthomalalisa iintlungu kwiinyanga ezininzi. Nangona kunjalo, banokwenza imikhwa ukuba bangathathwa njengoko kuyalelwe kwaye phantsi kokhathalelo lomboneleli wezempilo.

Lithini ixabiso lentengiso leToradol?

Amaxabiso okuthengisa eToradol ayahluka ngokusekelwe kwikhemesti oyisebenzisayo. Nangona kunjalo, kunokwenzeka ukuba wehlise iindleko zakho ngokusebenzisa ikhadi lokonga elinye.

Amaqabane angabodwa kwiikhemesti ezingama-35,000 kwilizwe liphela ukukusindisa ukuya kuthi ga kuma-80% kumashumi amawaka amayeza. Thelekisa iindleko zamayeza kwiwebhusayithi yethu okanye usetyenziso ngaphambi kokugcwalisa amayeza akho.