Eyona >> Iziyobisi Vs. Umhlobo >> Humalog vs.Novolog: Umahluko, ukufana, kwaye kukuphi okungcono kuwe

Humalog vs.Novolog: Umahluko, ukufana, kwaye kukuphi okungcono kuwe

Iziyobisi Vs. Umhlobo

Izigidi zabantu baseMelika abanesifo seswekile basebenzisa i-insulin rhoqo, nokuba kungohlobo lwe-1 yeswekile, uhlobo lwe-2 yeswekile, okanye isifo seswekile sokukhulelwa. Ii-insulin ezinje ngeHumalog kunye neNovolog ziyimfuneko ukulawula amanqanaba eswekile yegazi kwabo banesifo seswekile. Kodwa yintoni umahluko phakathi kwezi mveliso ze-insulin?

I-Humalog kunye ne-Novolog zi-insulins ezisebenza ngokukhawuleza ezisebenza ngokukhawuleza kwaye zihlala ixesha elifutshane ngokuthelekiswa nezinye i-insulins. Zingalawulwa ngaphambi kwesidlo ukulawula amanqanaba eswekile yegazi okanye ngokuqhubekekayo imini yonke ngempompo ye-insulin. I-insulin isebenza ngokwandisa ukufunwa kweswekile kwiiseli zomzimba zamandla. Iswekile (iswekile) ibalulekile kwimveliso yamandla kunye nemisebenzi yomzimba iyonke.

I-Humalog kunye ne-Novolog inokusebenza ngeendlela ezifanayo. Kodwa azitshintshi. Intsingiselo, enye ayinakutshintshwa enye. Kungenxa yokuba banomahluko kwindlela emiselweyo nasetyenziswa ngayo.

Nguwuphi umahluko ophambili phakathi kweHumalog kunye neNovolog?

I-Humalog yi-analog esebenza ngokukhawuleza ye-insulin eyavunywa yi-FDA ngo-1996. Iyafana ne-insulin yomntu enesakhiwo semichiza esifanayo. I-Humalog, ekwabizwa ngegama layo eliqhelekileyo elithi insulin lispro, iyafumaneka njengesisombululo senaliti phantsi kolusu (ongama).

I-insulin ye-Humalog iza nge-10 mL kunye ne-3 mL yeebisi ezineedosi ezininzi kunye neekhatriji ezi-3 ml kunye neepeni ezizaliswe kwangaphambili (Humalog KwikPen, Humalog Tempo Pen, Humalog Junior KwikPen). Zonke iifomathi zeHumalog ziqulethe iiyunithi ezili-100 / ml (U-100) ze-insulin ngaphandle kweHumalog KwikPen, ekwavela kwiiyunithi ezingama-200 / mL (U-200).

I-Novolog yi-analog esebenza ngokukhawuleza ye-insulin eyaziwa ngegama layo eliqhelekileyo elithi insulin aspart. Ifana ngokwamachiza ne-insulin eqhelekileyo yomntu ngaphandle kokuba ine-aspartic acid endaweni ye-proline amino acid kwinxalenye yesakhiwo se-DNA. I-Novolog yayivunywe yi-FDA ngo-2000.

NjengoHumalog, uNovolog uyafumaneka njenge-10 mL yedosi yeedosi ezininzi kwizigulana okanye ababoneleli bokuzoba isirinji yabo. I-Novolog iza kwakhona kwi-3 mL cartridge (PenFill cartridges) kunye neepeni ezizaliswe kwangaphambili (i-Novolog FlexPen, i-Novolog FlexTouch). Ezi fomula ziqulathe iiyunithi ezili-100 / ml ye-insulin aspart.

Umahluko ophambili phakathi kweHumalog kunye neNovolog
	Uhlobo	I-Novolog
Iklasi yeziyobisi	I-insulin	I-insulin
Uhlobo lweBrith / generic	Ibhranti kunye nohlobo oluqhelekileyo olukhoyo	Ibhranti kunye nohlobo oluqhelekileyo olukhoyo
Ngubani igama eliqhelekileyo?	Inaliti ye-insulin lispro	Inaliti ye-insulin aspart
Zeziphi iifom eza nalo iziyobisi?	Isisombululo ngenaliti ongama	Isisombululo ngenaliti ongama
Ithini idosi esemgangathweni?	Iidosi ze-insulin ziyahluka kakhulu kwaye kufuneka zimiselwe ngokusekwe kwimeko yomntu, ukutya, kunye nendlela yokuphila. Ukusebenza ngokukhawuleza kwe-insulin kuhlala kunikwa amaxesha ama-2 ukuya kuma-4 yonke imihla ngaphambi okanye emva kwesidlo kwinqanaba lomthamo weyunithi ye-0.5 ukuya kwi-1 yeyunithi / kg / ngosuku.
Lude kangakanani unyango oluqhelekileyo?	Isifo seswekile sisifo esiqhubela phambili esidla ngokufuna ulondolozo lobomi kunye ne-insulin.
Ngubani oqhelekileyo usebenzisa amayeza?	Abantu abadala abane-Type 2 diabetes Abantu abadala kunye nabantwana abaneminyaka emi-3 nangaphezulu ngohlobo lweswekile 1	Abantu abadala abane-Type 2 diabetes Abantu abadala nabantwana abaneminyaka emi-2 nangaphezulu ngohlobo lweswekile 1

Iimeko eziphathwe ngeHumalog kunye neNovolog

Zombini i-Humalog kunye ne-Novolog ziindidi zegama le-insulin esoloko imiselwe ukulawula iswekile yegazi kubantu abanesifo seswekile. Ezi insulins ezisebenza ngokukhawuleza zivunyiwe ukuba zinyange abo bane-Type 1 okanye Type 2 diabetes.

I-Humalog kunye ne-Novolog ikwasetyenziselwa ngaphandle kwelebheli ukunyanga isifo seswekile, okanye isifo seswekile esenzeka kubafazi abakhulelweyo. Abasetyhini abanemingcipheko yesifo seswekile kunokwenzeka ukuba bafumane amava isifo seswekile ngexa lokukhulelwa. Ii-insulins ezinje ngeHumalog kunye neNovolog ziyasetyenziselwa ukunyanga isifo seswekile ketoacidosis, ingxaki enkulu enokubakho amanqanaba aphezulu e-ketone kwabo bane-Type 1 diabetes — kwaye kunqabile ukuba babe nohlobo lwesibini lweswekile.

Imeko	Uhlobo	I-Novolog
Uhlobo lwe-1 yeswekile	Ewe	Ewe
Uhlobo lwe-2 yeswekile	Ewe	Ewe
Isifo seswekile	Ngaphandle kwelebheli	Ngaphandle kwelebheli
I-ketoacidosis yeswekile	Ngaphandle kwelebheli	Ngaphandle kwelebheli

Ngaba i-Humalog okanye i-Novolog isebenza ngakumbi?

I-Humalog kunye neNovolog zibonelela ngokukhawuleza xa zilawulwa ngokuchanekileyo. I-insulin kufuneka inikezwe ngenaliti kwindawo yesisu, emathangeni, ezingalweni eziphezulu, okanye ezinqeni. Zombini i-Humalog kunye ne-Novolog zisebenza ngokulinganayo ukunciphisa amanqanaba eswekile yegazi.

Nangona zombini ii-insulini zisebenza ngokukhawuleza, uNovolog usebenza ngokukhawuleza kuneHumalog. I-Novolog inokufakwa ngaphakathi kwisithuba semizuzu emihlanu ukuya kweli-10 ngaphambi kokutya, ngelixa i-Humalog kufuneka itofwe kwisithuba semizuzu eli-15 ngaphambi kokutya.

Xa kuthelekiswa nezinye iintlobo ze-insulin, ii-insulins ezisebenza ngokukhawuleza zinokuba ziinketho ezingcono xa zisetyenziselwa ukulawula iswekile ngaphambi okanye emva kwesidlo. Kuhlalutyo lweemeta ukusuka Unyango lweswekile , Abaphandi bafumanisa ukuba i-insulin esebenza ngokukhawuleza yayisebenza ngakumbi njengexesha lokutya le-insulin yohlobo lwe-1 yeswekile xa kuthelekiswa ne-insulin eqhelekileyo. Ii-insulins ezisebenza ngokukhawuleza nazo zafunyanwa ziphucula Amanqanaba eHbA1c ngempumelelo ngakumbi kubantu abanesifo seswekile sohlobo 1.

Nokuba umiselwe i-Humalog, Novolog, okanye olunye uhlobo lwe-insulin luya kuxhomekeka kwimeko yakho iyonke. Nxibelelana nomboneleli wezempilo ukuze ufumane eyona insulin ifanelekileyo.

Ukufunda kunye nokuthelekiswa kweendleko zeHumalogs ngokuchasene neNovolog

I-Humalog kunye ne-Novolog ziyafumaneka kwi-brand kunye neefom generic. Ezinye, kodwa ayizizo zonke izicwangciso ze-Medicare Icandelo D eziza kugubungela i-insulin ngaphandle kokuba ilawulwa ngempompo ye-insulin. Xa i-insulin kufuneka inikezelwe ngempompo ye-insulin, icandelo leMedicare B linokuhlawula iindleko zalo. Jonga kwifomula yakho yesicwangciso seinshurensi ukuze ubone ukuba zeziphi ezigutyungelweyo kunye neendleko zakho zokuphuma epokothweni.

Nokuba isicwangciso sakho seinshurensi sigubungela i-insulin, unokugcina ngakumbi ngekhadi le-SingleCare. Ixabiso leHumalog generic linokufikelela kwi- $ 300. Ngekhuphoni ye-SingleCare, imalunga ne- $ 145. Kwangokunjalo, ikhuphoni likaNovolog linokunciphisa ixabiso ukusuka kwi- $ 300 ukuya kuthi ga kwi-150 yeedola kwi-10 ml vial. Gcina ukhumbula, amaxabiso e-insulin ayahluka phakathi kweebhotile kunye neekhatriji.

	Uhlobo	I-Novolog
Ngokuqhelekileyo i-inshurensi?	Isenokugqunywa; kuxhomekeke kwisicwangciso seinshurensi	Isenokugqunywa; kuxhomekeke kwisicwangciso seinshurensi
Ngokuqhelekileyo igutyungelwe yiMedicare?	Isenokugqunywa; kuxhomekeke kwisicwangciso seinshurensi	Isenokugqunywa; kuxhomekeke kwisicwangciso seinshurensi
Umthamo osemgangathweni	10 ml ye-vial (idosi iyahluka)	10 ml ye-vial (idosi iyahluka)
I-Medicare copay eqhelekileyo	$ 318	$ 335
Ixabiso elilodwa	$ 140- $ 150	$ 146- $ 155

Iziphumo eziqhelekileyo ezichaphazelekayo zeHumalogs ngokuchasene neNovolog

Iziphumo ebezingalindelekanga ezixhaphakileyo zeHumalog zibandakanya intloko ebuhlungu, isicaphucaphu, urhudo, isisu esibuhlungu (iintlungu zesisu), umqala obuhlungu (pharyngitis), impumlo ebusy (rhinitis), kunye nobuthathaka bemisipha (asthenia).

Iziphumo eziqhelekileyo zeNovolog zibandakanya intloko ebuhlungu, isicaphucaphu, urhudo, iintlungu zesisu, i-rhinitis, iintlungu zesifuba kunye nokuphazamiseka kwovakalelo.

Ezinye iziphumo ebezingalindelekanga ze-insulin zinokubandakanya iintlungu zalapha ekhaya, ukutshisa, ukurhawuzelela, okanye ukucaphuka malunga nendawo yenaliti. Uninzi lweziphumo ebezingalindelekanga ziphakathi. Nangona kunjalo, iimpendulo ezimbi kakhulu ezinokuthi zenzeke kulabo banomdla kwizithako ze-insulin.

	Uhlobo	I-Novolog
Imiphumela	Iyasebenza?	Rhoqo	Iyasebenza?	Rhoqo
Intloko ebuhlungu	Ewe	24%	Ewe	12%
Isicaphucaphu	Ewe	5%	Ewe	7%
Urhudo	Ewe	7%	Ewe	5%
Isisu esibuhlungu	Ewe	6%	Ewe	5%
Umqala obuhkungu	Ewe	27%	Hayi	N / A
Impumlo enemifinya	Ewe	Amashumi amabini%	Ewe	5%
Ubuthathaka bemisipha	Ewe	6%	Hayi	N / A
Iintlungu zesifuba	Hayi	N / A	Ewe	5%
Ukuphazamiseka kwendlela	Hayi	N / A	Ewe	9%

Olu alunakuba luluhlu olupheleleyo lweziphumo ezibi ezinokwenzeka. Nceda ujonge ugqirha wakho okanye umboneleli wezempilo ukuze ufunde okungakumbi.
Umthombo: DailyMed ( Uhlobo ), Yonke imihla ( I-Novolog )

Ukudibana kweziyobisi kwiHumalogs ngokuchasene neNovolog

I-Humalog kunye ne-Novolog insulin inokusebenzisana neziyobisi ezahlukeneyo. Iiarhente ze-Antidiabetic, ezinje nge-glipizide okanye i-glyburide, ngamanye amaxesha zisetyenziswa kunye ne-insulin ukunceda ukulawula amanqanaba eswekile yegazi. Nangona kunjalo, ukusebenzisa la machiza nge-insulin kunokonyusa umngcipheko wamanqanaba eswekile esegazini eyingozi, okanye i-hypoglycemia.

ICorticosteroids efana ne-prednisone okanye i-dexamethasone inokunyusa amanqanaba eglucose egazini. Ke ngoko, ukuthatha la machiza kunokunciphisa iziphumo ze-insulin. Ukuthatha iziyobisi njenge-antipsychotic okanye i-diuretics kunokunciphisa iziphumo ze-insulin kunye nokunyusa ukunganyangeki kwe-insulin. Iidosi ze-insulin zingadinga ukuhlengahlengiswa xa usela amanye amayeza.

Beta-iibhlokhi Unokutshintsha iziphumo ze-insulin. Ukongeza, ii-beta-blockers zinokufihla imiqondiso ye-hypoglycemia enokuthi yenzeke emva kokuthatha idosi engalunganga ye-insulin. Oku kunokudala imeko enobungozi efuna ukubekwa esweni.

Tshela ugqirha wakho malunga nalo naliphi na iyeza olithathayo ukuthintela ukubakho kokunxibelelana kweziyobisi.

Iziyobisi	Iklasi yeziyobisi	Uhlobo	I-Novolog
IGlipizide IGlyburide Isigaba I-Repaglinide	Iiarhente ezichaseneyo neswekile	Ewe	Ewe
IPrednisone IPrednisolone Dexamethasone	ICorticosteroids	Ewe	Ewe
IClozapine Olanzapine	I-antypychychotic ye-Atypical	Ewe	Ewe
IHydrochlorothiazide IChlorthalidone	Womchamo	Ewe	Ewe
Ipropranolol UNadolol ILabetalol	Beta-iibhlokhi	Ewe	Ewe

* Qhagamshelana neengcali zonyango malunga nolunye unxibelelwano lweziyobisi.

Izilumkiso zeHumalog kunye neNovolog

Kuhlala kukho umngcipheko we-hypoglycemia xa usebenzisa ii-insulins ezinje ngeHumalog okanye iNovolog. Iimpawu zeswekile esezantsi yegazi inokubandakanya isicaphucaphu, indlala, ukudideka kunye nobuthathaka. Ngesi sizathu, kuyacetyiswa ukuphatha iipilisi zeswekile ukunceda ukulwa nale meko inokubusongela ubomi. Unyango kunye namanye amayeza kufuneka alungelelaniswe ngononophelo ukuqinisekisa ukuba inani elifanelekileyo le-insulin lilawulwa.

Kuya kufuneka uphephe ukusebenzisa i-Humalog okanye i-Novolog ukuba unemvakalelo eyaziwayo kuyo nayiphi na into esebenzayo. Ukuphendula kwe-Hypersensitivity kungabandakanya irhashalala okanye ingxaki yokuphefumla (anaphylaxis).

Iisirinji, iipeni ezigcwaliswe kwangaphambili, kunye neekhatriji akufuneki zabelwe nabanye abantu abanesifo seswekile. Ukusebenzisa isixhobo se-insulin somnye umntu kunokubeka esichengeni sokufumana i-HIV.

Qhagamshelana nomboneleli wakho wezempilo malunga nezinye iindlela zokukhusela xa usebenzisa i-insulin.

Imibuzo ebuzwa rhoqo malunga neHumalogs ngokuchasene neNovolog

Yintoni uHumalog?

I-Humalog yi-analog esebenza ngokukhawuleza esetyenziselwa ukulawula iswekile yegazi kwabo banesifo seswekile. Kuvunyiwe yi-FDA ukunyanga i-Type 2 diabetes kubantu abadala kunye nohlobo 1 lweswekile kubantu abadala nakubantwana abaneminyaka emi-3 nangaphezulu. Uhlobo olufanelekileyo ligama lophawu lwe-insulin lispro.

Yintoni iNovolog?

I-Novolog yi-analog esebenza ngokukhawuleza ekwaziyo ukulawula amanqanaba eswekile egazini kubantu abanesifo seswekile. Kuvunyiwe yi-FDA ukunyanga i-Type 2 diabetes kubantu abadala kunye nohlobo 1 lweswekile kubantu abadala nakubantwana abaneminyaka emi-2 nangaphezulu. I-Novolog ligama lophawu lwe-insulin aspart.

Ngaba i-Humalog ne-Novolog ziyafana?

Hayi, iHumalog kunye neNovolog azifani. Banendlela eyahlukileyo eyahlukileyo, uthintelo lobudala, kunye neendleko ezinxulumene nokusetyenziswa kwazo.

Ngaba uHumalog okanye uNovolog ungcono?

I-Humalog kunye ne-Novolog zombini ziyasebenza ekunciphiseni i-glucose yegazi. Nangona kunjalo, iNovolog isebenza ngokukhawuleza kancinci kuneHumalog. Xa kuthelekiswa ne-insulins esebenza ixesha elide njengeLantus (insulin glargine), ii-insulins ezisebenza ngokukhawuleza zilungele ukulawula amanqanaba eswekile yegazi ngaphambi nasemva kwesidlo. Nxibelelana nomboneleli wezempilo ngeyona insulin ibalaseleyo kwimeko yakho.

Ndingayisebenzisa i-Humalog okanye i-Novolog ngelixa ndikhulelwe?

Ngokwe- Umbutho weSwekile yaseMelika , I-insulin lunyango lokuqala lonyango lokulawula isifo seswekile ngelixa ukhulelwe. Ayifumanekanga ukuba iwele i-placenta. Ngoko ke, kuthathwa njengokukhuselekileyo ukusetyenziswa ngexesha lokukhulelwa.

Ndingayisebenzisa i-Humalog okanye i-Novolog ngotywala?

Utywala kufuneka kuthintelwe ngelixa usebenzisa i-insulin. Kungenxa yokuba utywala bunokunyusa iswekile esehla kwiziphumo ze-insulin kunye ezinokubangela i-hypoglycemia .

Nguwuphi umahluko phakathi kwe-insulin lispro kunye ne-insulin aspart?

I-insulin lispro kunye ne-insulin aspart ziindlela ezimbini eziqhelekileyo ze-insulin esebenza ngokukhawuleza. Nangona kunjalo, bahlukile ngokwamachiza ngeendlela ezahlukeneyo zentshukumo. I-insulin lispro isebenza ngaphakathi kwemizuzu eli-15 ngelixa i-insulin aspart isebenza kwisithuba semizuzu emihlanu ukuya kweli-10. Enye i-insulin isenokuba ngexabiso eliphantsi kunenye ngokuxhomekeke kwisicwangciso sakho seinshurensi.

Yeyiphi i-insulin ethelekiswa neNovoLog?

I-Novolog ithelekiswa nezinye ii-insulins ezisebenza ngokukhawuleza ezinje ngeHumalog (insulin lispro) kunye neApidra (insulin glulisine). Ngenxa yokukhawuleza kokusebenza kwabo, i-Novolog, i-Humalog kunye ne-Apidra zihlala zisetyenziswa njenge-insulins yexesha lokutya. Bathatha imizuzu engaphantsi kwama-20 ukuqala ukusebenza kwaye bahlala ixesha elipheleleyo elimalunga neeyure ezine.