Yintoni iVivvanse kwaye isetyenziselwa ntoni?

Ulwazi lweziyobisi

Yintoni iVavvanse? | Ingaba isebenza kanjani | Imithamo | Ulwazi ngokhuseleko | Ezinye iindlela zikaVyvanse | IVivvanse vs Adderall

I-Vyvanse sisiyobisi esikhuthazayo esinokunyanga ukungabinakho ukuphazamiseka (ADHD) kunye nokutya okuneengxaki zokutya (BED). Inceda ukunciphisa iimpawu ze-ADHD ezinje ngokungakhathalelwa, ukulibala, kunye noxinzelelo. Inokukunceda ukulawula ukuthanda ukutya kubantu abanengxaki yokutya kakhulu. Apha ngezantsi, siza kujonga ukuba yintoni iVivvanse kwaye ithelekiswa njani namanye amayeza.

Ezinxulumene: Fumana amatikiti eVyvanse | Funda ngakumbi malunga noVyvanse

Yintoni iVivvanse, kwaye isetyenziselwa ntoni?

I-Vyvanse (lisdexamfetamine dimesylate) sisiyobisi esenziwe ngu-Shire Pharmaceuticals. Akukho luhlobo luqhelekileyo lweli yeza.

Eli yeza livuselelayo liqukethe i-lisdexamfetamine, iprodrug ye-amphetamine. Yinkqubo yeshedyuli II elawulwayo enobuchule obuphezulu bokusetyenziswa gwenxa, ukusetyenziswa gwenxa, kunye nokuxhomekeka.

I-Vyvanse ye-ADHD

IVivvanse isetyenziselwa i Unyango lwe-ADHD ngokuphucula ukugxila kunye nokunciphisa ukungxamiseka kunye nokuziphatha okungafunekiyo. Kuvunyiwe kwizigulana ezine-ADHD ezineminyaka emi-6 ubudala okanye ngaphezulu. Ukususela ngo-2016, Iipesenti ezingama-62 zabantwana abane-ADHD Iminyaka emi-2 ukuya kweli-17 ubudala babethatha amayeza e-ADHD. Izifundo zonyango Kubantwana abane-ADHD bafumanise ukuba uVyvanse uphucule kakhulu indlela yokuziphatha, esekwe kwi-ADHD Scale Scale (ADHD-RS), xa kuthelekiswa ne-placebo.

Vyvanse yokutya kakhulu

Ukuphazamiseka kwindlela otya ngayo kuku isifo esiqhelekileyo sokutya eMelika , kwaye ibonakaliswa ngokutya ukutya okuninzi ngexesha elifutshane. Abantu abanengxaki yokutya kakhulu xa beziva beziva bengenako ukulawula ukuthanda kwabo ukutya.

Izifundo bonisile ukuba iVivvanse inciphisa inani lokutya kakhulu kwiintsuku zokutya kakhulu ngeveki xa kuthelekiswa ne-placebo. Iqukumbele ukuba i-50 ukuya kwi-70 mg ngemini iluncedo kwabo banengxaki yokutya kakhulu.

Ngapha koko, uVyvanse nguye kuqala kwaye kwamkelwe kuphela amayeza yi-United States yokutya kunye noLawulo lweeDrug (i-FDA) ukunceda ukuphatha ingxaki yokutya kakhulu. Nangona kunjalo, iingcali azicebisi uVyvanse ukunciphisa umzimba okanye ukunyanga ukutyeba.

Usebenza njani uVyvanse?

I-Vyvanse yiprodrug, oko kuthetha ukuba iyenziwa kuphela xa yenziwe umzimba, okanye iqhutywa emzimbeni. I-lisdexamfetamine iguquka ibe yi-dextroamphetamine xa ifikelela kwithumbu lesisu (GI). I-Dextroamphetamine isebenza kwinkqubo ye-nervous system (CNS) kwaye yonyusa umsebenzi we-dopamine kunye ne-norepinephrine kwingqondo.

I-Dopamine kunye ne-norepinephrine zii-neurotransmitters ezinokuthi zichaphazele ukuhoywa komntu, imeko yakhe kunye nenkuthazo yakhe. Abantu abane-ADHD banokuba namanqanaba asezantsi edopamine kunye nomsebenzi we-norepinephrine, obangela ukuba babe neengxaki ngokujonga, ukungasebenzi kakuhle, okanye ukungxamiseka.

I-Vyvanse ibhloka ukuphinda kuthathwe i-dopamine kunye ne-norepinephrine neurotransmitters, enokunceda ukuphucula uxinzelelo kunye nokuziphatha okungxamisekileyo kwabo bane-ADHD.

Uyithatha njani iVivvanse

UVyvanse uhlala emiselwe ukuba athathwe kanye ngemini, kusasa-nokuba kungaphandle kokutya. Iidosi zisusela kwi-30 kuye kwi-70 mg. IVivvanse iyafumaneka njengephilisi yomlomo eqala ukusebenza kwiyure enye emva kokuyithatha. Ifikelela incopho yayo malunga neeyure ezine, kwaye iziphumo zinxiba emva kweeyure ezili-14. UVyvanse uza nepilisi ekhutshiweyo yokukhululwa enokunceda ukuphucula ukubambelela kunyango kunye nokunciphisa ukubakho iziphumo eziphindiweyo Ekupheleni kosuku.

Ngokwesiqhelo, idosi kaVyvanse yesigulana esitsha iya kuqala nge-30 mg. Umthamo ophezulu akufuneki uthathwe ngaphandle kwemvume yomboneleli kuba kubalulekile ukuvavanya indlela umntu asabela ngayo kunyango kuqala.

IVivvanse iyafumaneka njengephilisi yomlomo kunye nethebhulethi ehlafunwayo. Iifomsile zomlomo ziza ngamandla e-10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, kunye 70 mg. Amacwecwe ahlafunwayo eza ngamandla e-10 mg, 20 mg, 30 mg, 40 mg, 50 mg, kunye 60 mg.

I-capsule yomlomo inokulawulwa ngeglasi yamanzi okanye ijusi, okanye imixholo yecapsule ingaxutywa nokutya, njengeyogathi. Vula nje iphilisi kwaye udibanise umgubo kukutya kwakho. Khumbula ukuba ukutya okune-vitamin C enjengejusi yeorenji kunokunciphisa amandla omzimba okufumana iVivvanse, enokunciphisa ukusebenza kweyeza.

Ukugqithisa, iidosi eziphosiweyo, kunye nokurhoxa

Unokudlula kwi-Vyvanse ukuba uyithatha ngokungafanelekanga. Iimpawu zokusebenzisa ngaphezulu kweVivvanse zibandakanya ukubona izinto ezingekhoyo, uvalo, iinyikima, ukungonwabi, ukudideka, ukuphefumla ngokukhawuleza, kunye nentlungu yomhlunu.

Ukuba uphosa idosi yeVivvanse, yithabathe kwangoko xa ukhumbula. Nangona kunjalo, ukuba sele kuhlwile, kungcono ukutsiba idosi yolo suku. Ungaze uthathe idosi eyongezelelweyo ukwenza idosi ephosiweyo.

Unokufumana ukurhoxa xa uyeka ukuthatha iVyvanse ngesiquphe. Iimpawu zokurhoxa zinokubandakanya ukushukuma, ukubila, ukuba nochuku, ukudinwa kunye noxinzelelo. Njengoko iyeza liphela imini yonke, abanye abantu banokufumana ingozi. Ingozi kaVyvanse iqhelekile ingakumbi xa uqala ichiza, kwaye iimpawu zinokufana nezo zokurhoxa, njengokucaphuka kunye nokudinwa. Qhagamshelana nomboneleli wakho wezempilo ukuba ufumana ezi mpawu rhoqo.

Jonga isikhokelo sakho sonyango seVivvanse ngolwazi oluthe kratya malunga nokuba ungamthatha njani uVyvanse.

Ukugcina

Gcina iVivvanse kubushushu begumbi phakathi kwama-68 ukuya kuma-77 degrees F. Yigcine kude nokukhanya ukuyiphepha ukuba shushu ngokugqithisileyo.

Kungcono ukugcina iVivvanse kwigumbi elitshixiweyo, ngakumbi ukuba uhlala nabantwana.

Ukuba umboneleli wakho wezempilo uyalela ukuba uyeke ukuthatha iVivvanse ngaphambi kokuba ugqibe amayeza akho, musa ukuwaphosa emgqomeni. Inokonzakalisa izilwanyana kunye nabantu abafumana iVivvanse. Endaweni yoko, jonga amayeza okubuyisela inkqubo kwikhemesti yakho yasekuhlaleni. Funda malunga nendlela yokwenza lahla amayeza ngokufanelekileyo ngolwazi oluthe kratya.

Ulwazi ngokhuseleko lweVyvanse

Izithintelo

Akufuneki uthathe iVivvanse ukuba:

• Umncinci kuneminyaka emi-6 ubudala
• Ebuthathaka okanye yokugulisa amanye amayeza avuselelayo
• Ukuthatha iyeza le-monoamine oxidase inhibitor (MAOI) okanye uthathe i-MAOI kwiintsuku ezili-14 ezidlulileyo

Uluhlu oluvunyiweyo lwe-FDA lwe-MAOIs lubandakanya iMarplan (isocarboxazid), iNardil (phenelzine), i-Emsam (selegiline), kunye neParnate (tranylcypromine). Ukuthatha ii-MAOIs ngeVyvanse kunokunyusa umngcipheko isifo se-serotonin .

Thetha nogqirha wakho ukuba uye waphendula kakubi kwiVivvanse okanye ezinye iyeza ze-ADHD ngaphambili.

Izilumkiso

UVivvanse angalonyusa izinga lokubetha kwentliziyo yakho kunye noxinzelelo lwegazi. Ke ngoko, abo baneengxaki zentliziyo okanye abanesiphene sentliziyo kufuneka bathethe nomboneleli wabo wezempilo ngaphambi kokuba bathathe uVyvanse. La mayeza axelwe ukuba abangela ukufa ngesiquphe kwizigulana ezineemeko zentliziyo.

Xelela umboneleli wakho wezempilo ukuba ukhulelwe okanye ucwangcisa ukukhulelwa. Akukho datha inamandla malunga nokuba uVyvanse uzichaphazela njani iimveku okanye iintsana ezingekazalwa. Funa iingcebiso zonyango ukuba ufuna amayeza e-ADHD ngelixa ukhulelwe okanye uncancisa.

Izinto ezilawulwa ngokusesikweni ezifana neVivvanse zinomngcipheko omkhulu wokuxhomekeka kuba idosi ephezulu inokwenza abanye abasebenzisi bazive benovuyo. Nangona kunjalo, ukusetyenziswa gwenxa kukaVyvanse kunokuba nemiphumela emibi kwaye ibulale impilo.

Imiphumela

Iziphumo ebezingalindelekanga zikaVyvanse zokunyanga i-ADHD kunye nokutya kakhulu kukutya kubandakanya:

• Ixhala
• Ukunciphisa ukutya
• Umlomo owomileyo
• Ingxaki yokulala
• Ukucaphuka

Ezinye iziphumo ebezingalindelekanga ezinxulunyaniswa neVyvanse kwi-ADHD zibandakanya:

• Intlungu ephezulu esiswini
• Ukuba nesiyezi
• Isicaphucaphu
• Ukuhla ukusinda
• Urhudo

Abantu abanengxaki yokutya kakhulu abathatha iVivvanse banokuba namava:

• Ukuqunjelwa
• Ukunyuka kwentliziyo

I-Vyvanse isenokuba mancinci amathuba okubangela inkungu yengqondo kunamanye amayeza e-ADHD, kwaye, ekulibazisekeni-ukukhutshwa kwefomule yefomule, uVivvanse unokuphucula ngokufanelekileyo ukugxila kwimini yonke. Ukuqhubeka okanye ukuhla kweempembelelo kunokufuna idosi eyahlukileyo okanye utshintsho kunyango.

Unxibelelwano

Zininzi Ukusebenzisana kweziyobisi kunye noVyvanse . Olunye lolwalamano oluyingozi kakhulu kwiVyvanse lubandakanya:

• Ii-MAOIs, ezinje nge-tranylcypromine, isocarboxazid, kunye ne-selegiline
• Ezinye zoxinzelelo, ezinje nge-SSRIs, i-SNRIs, kunye ne-tricyclic antidepressants
• CYP2D6 inhibitors, ezinje ngeparoxetine, ritonavir, kunye nequinidine
• Iiarhente zealkalinizing, ezinje ngeacetazolamide
• Ukunyusa iiarhente, ezinjenge ammonium chloride

I-Vyvanse, njengamanye amayeza e-ADHD, ihlala icetyiswa ukuba ithintelwe ngotywala . Ukudibanisa iVivvanse kunye notywala kunokunyusa umngcipheko weziphumo ezibi. UVivvanse uyakhuthaza ngelixa utywala bunxunguphalisa. Ukuxuba ezi zimbini kunokubangela nokusela kakhulu okanye utywala obugqithisileyo kwiVivvanse.

Ezinye iindlela zikaVyvanse

Zithini izibonelelo kunye nokungalunganga kukaVyvanse xa kuthelekiswa namanye amayeza e-ADHD? Kuxhomekeka kwizinto ezahlukeneyo ezinjengeendleko kunye neziphumo ebezingalindelekanga. Ezinye iindlela ezinokubakho ze-ADHD zibandakanya:

• URitalin (imethylphenidate): I-Ritalin sisikhuthazi esisetyenziselwa ukunyanga i-ADHD kunye ne-narcolepsy, kodwa hayi ukuzinkcinkca ngokutya.
• Ikonsathi (imethylphenidate): I-Concerta luhlobo lokukhululwa olwandisiweyo lwe-methylphenidate, isithako esinye eRitalin.
• Adderall (amphetamine / dextroamphetamine): I-Adderall ayisiyeprodrug, ngokungafaniyo neVyvanse, enokuthi ivelise iziphumo ezahlukeneyo kwabanye abantu. I-Adderall XR yinguqulelo ekhutshiweyo yeAdderall.
• Focalin (dexmethylphenidate): I-Focalin (dexmethylphenidate) sishukumisi esisebenza kancinci esifana neAdderall. Kodwa i-methylphenidate inokusebenza ngakumbi kunee-amphetamine ezifana neAdderall yabantwana.

Ngaba uVyvanse ungcono kuneAdderall?
	Vyvanse	Adderall
Izinto ezisebenzayo	I-Lisdexamfetamine dimesylate	I-Dextroamphetamine amphetamine
Uhlobo lweBrith / generic	Igama lebrand kuphela	Brand kunye generic ziyafumaneka
Iklasi	Ukukhuthaza i-CNS	Ukukhuthaza i-CNS
Idosi esemgangathweni kunye nexesha	Ye-ADHD (6+ iminyaka ubudala): I-30 mg ukuya kwi-70 mg kanye ngemini kusasa. Ukuphazamiseka kokutya kakhulu: 50 mg ukuya kwi-70 mg qho kusasa. Idosi enye yeVivvanse inokuhlala iiyure ezili-14.	Kwi-ADHD (iminyaka emi-3-5 ubudala): 2.5 ukuya kuma-40 mg yonke imihla. Unokuthatha amanani ama-1-3 ngosuku. Ye-ADHD (6+ iminyaka ubudala): 5 ukuya kuma-40 mg yonke imihla. Unokuthatha amanani ama-1-3 ngosuku. Idosi yeAdderall inokuhlala iiyure ezi-4. Nangona kunjalo, i-Adderall XR inokuhlala iiyure eziyi-8 ukuya kwezi-12.
Iziphumo eziqhelekileyo ezichaphazelekayo *	Ixhala Umlomo owomileyo Ukuphuthelwa Ukunciphisa ukutya Ukuhla ukusinda	Ukuphelelwa ngumdla wokutya Ukuhla ukusinda Ukuphuthelwa Intlungu yesisu Uvalo Isicaphucaphu Imood iyatshintsha

Iziphumo ebezingalindelekanga ziyahluka ngokwedosi, ubudala, kunye nesalathiso.

UVyvanse uza njengepilisi yomlomo ebambezelekileyo, ngelixa iAdderall yithebhulethi ekhupha kwangoko. Nangona kunjalo, i-Adderall XR yindlela eyandisiweyo yokukhutshwa kweAdderall. Abanye abantu baxhamla kunyango olukhutshwa kwangoko ukuba ukukhutshwa okwandisiweyo kuthatha ixesha elide ukuba kusebenze. Iziphumo kunye nezinto ozikhethayo zinokwahluka.

I-Adderall ifumaneka ngeedosi ezincinci kwabo baphakathi kweminyaka emi-3 ukuya kwemi-5 ubudala. Ngokwahlukileyo, uVyvanse wenzelwe kuphela abo baneminyaka emi-6 nangaphezulu.

Akukhuselekanga ukuthatha iVivvanse neAdderall ngaphandle kommiselo ovela kugqirha kwezonyango. I-Vyvanse ne-Adderall akufunekanga zithathwe kunye kuba ziqulathe izithako ezineziphumo ezifanayo. Ukuthatha la mayeza kunye kunokunyusa umngcipheko weziphumo ezibi.

Ekugqibeleni, umntu unokukhetha uVyvanse ngaphezulu kweAdderall ngokuxhomekeke kwimpendulo yabo kunyango nakwiziphumo ebezingalindelekanga abanokuzifumana. Nxibelelana nomboneleli wezempilo ukumisela iyeza elifanelekileyo le-ADHD kwimeko yakho.

Okukwintsusa-thetha nomboneleli wezempilo ukuze ufunde okungakumbi malunga nokuba i-Adderall okanye i-Vyvanse ikulungele na.