I-Zanaflex vs.Flexeril: Umahluko, ukufana, kwaye kukuphi okungcono kuwe

Iziyobisi Vs. Umhlobo

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Igama leBrand Flexeril liphelile; Nangona kunjalo, isekhona njenge-generic-cyclobenzaprine-nanjengamagama egama u-Amrix noFexmid.

I-Zanaflex (tizanidine) kunye ne-Flexeril (cyclobenzaprine) zizidambisi zezihlunu ezisetyenziselwa ukunyanga iimeko ezibuhlungu zemisipha. Ukuba unentamo okanye umqolo obuhlungu, unokucetyiswa ukuba ukhululeke njengesiZanaflex okanye iFlexeril. La machiza anokunceda ekunciphiseni ukungqubana kwemisipha kunye nokuqina okuhambelana nezinye iimeko zomzimba kunye nokulimala.

Njengabanye izihlunu eziphumlayo , Zanaflex kunye neFlexeril basebenza kwinkqubo ye-nervous system (CNS). Banazo iziphumo ebezingalindelekanga ezifanayo kunye neendleko. Nangona kunjalo, banomahluko kwindlela ezisetyenziswa kunye nendlela ezenziwa ngayo.

Nguwuphi umahluko ophambili phakathi kweZanaflex kunye neFlexeril?

Zanaflex

I-Zanaflex (Yintoni iZanaflex?) Ligama lophawu lwe-tizanidine kwaye lisebenza njenge-alpha-2 adrenergic agonist. Kwavunywa okokuqala ngo-1996 kunyango lwe-muscle spasticity. Nangona indlela echanekileyo yokusebenza ingaziwa, kukholelwa ukuba iyalawula Ukuxhamla kwemisipha Ngokuthintela imiqondiso yemithambo-luvo yemoto.

I-Zanaflex iyafumaneka njengecwecwe lomlomo kumandla e-2 mg kunye ne-4 mg. Kuza njengephilisi yomlomo ngamandla e-2 mg, 4 mg, kunye no-6 mg. I-Zanaflex ihlala ithathwa kathathu ngemini.

Flexeril

I-Flexeril (Yintoni i-Flexeril?) Sisiyobisi esinegama elibizwa ngokuba yi-FDA-evunyiweyo ngonyaka ka-1977. Uhlobo oluqhelekileyo lwe-Flexeril, i-cyclobenzaprine, iyafumaneka jikelele. I-Flexeril ngokwendlela efanayo ne-tricyclic antidepressants kwaye isebenza ikakhulu kwinkqubo ye-nervous system (CNS). Inceda ukunciphisa ukungasebenzi kakuhle kwemisipha ngezenzo ezikwinkqubo ye-gamma- kunye ne-alpha-motor system.

I-cyclobenzaprine ayisafumaneki njengeFlexeril. Endaweni yoko, i-cyclobenzaprine inokufumaneka phantsi kwamagama eebhendi ezahlukeneyo: i-Amrix (ukukhutshwa okwandisiweyo) kunye neFexmid (ukukhutshwa kwangoko). Ukukhutshwa kwangoko kwe-cyclobenzaprine kuthathwa ukuya kathathu ngemini ngelixa ifom ekhutshiweyo inokuthathwa kube kanye yonke imihla.

Umahluko ophambili phakathi kweZanaflex kunye neFlexeril
	Zanaflex	Flexeril
Iklasi yeziyobisi	Izihlunu ziyaphumla	Izihlunu ziyaphumla
Uhlobo lweBrith / generic	Ibhranti kunye nohlobo oluqhelekileyo olukhoyo	Ibhranti kunye nohlobo oluqhelekileyo olukhoyo Igama lebrand uFlexeril unqunyanyisiwe eMelika Amanye amagama egama libandakanya uAmrix noFexmid.
Ngubani igama eliqhelekileyo?	Tizanidine	ICyclobenzaprine
Zeziphi iifom eza nalo iziyobisi?	Ithebhulethi yomlomo Iifomsile zomlomo	Ithebhulethi yomlomo I-capsule yomlomo, ukukhutshwa kwexesha elide
Ithini idosi esemgangathweni?	Idosi yokuqala ye-2 mg, elandelwa ngamathamo alandelayo rhoqo emva kweeyure ezi-6 ukuya kwezi-8. Ubuninzi beedosi ezi-3 kwiiyure ezingama-24. Idosi inokwandiswa rhoqo kwiintsuku ezi-1 ukuya kwezi-4 nge-2 mg ukuya kwi-4 mg. Ubuninzi beedosi zemihla ngemihla ezingama-36 mg.	Iipilisi zokukhululwa kwangoko: 5 mg ukuya kwi-10 mg kathathu ngemini. Iifomsile zokukhupha ezandisiweyo: 15 mg ukuya kwi-30 mg kanye yonke imihla.
Lude kangakanani unyango oluqhelekileyo?	Ixesha elifutshane okanye ixesha elide kuxhomekeke kwimeko	Akukho ngaphezulu kweeveki ezi-2 ukuya kwezi-3
Ngubani oqhelekileyo usebenzisa amayeza?	Abantu abadala abaneminyaka eli-18 nangaphezulu	Abantu abadala kunye nabantu abadala abancinci abaneminyaka eli-15 nangaphezulu

Ngaba ufuna elona xabiso lilungileyo kwiZanaflex?

Bhalisela izilumkiso zamaxabiso eZanaflex kwaye ufumane ukuba amaxabiso atshintsha nini!

Fumana izilumkiso zamaxabiso

Iimeko eziphathwe nguZanaflex kunye noFlexeril

Zombini iZanaflex kunye neFlexeril ziziyobisi ezisetyenziselwa ukuphazamiseka kwemisipha kunye isiqabu sentlungu ukusuka kwiimeko zemisipha. UZanaflex uqhele ukumiselwa ukuba anyange ukunganyamezeleki kwi-multiple sclerosis, cerebral palsy, kunye nokwenzakala kwethambo lomqolo. I-Flexeril ihlala imiselwe ukuba inciphise iintlungu zemisipha kunye ne-spasms ebangelwa zii-back and neck strains.

I-Zanaflex kunye ne-Flexeril ngamanye amaxesha zichazwe ngaphandle kwelebheli ukunyanga i-fibromyalgia kunye ne-migraines. Ihlala idityaniswe namanye amachiza, iZanaflex okanye iFlexeril inokunceda ekulawuleni ukuqina kwemisipha kunye nokungcangcazela okunxulunyaniswa ngqi .

Imeko	Zanaflex	Flexeril
Ukudumba kwezihlunu	Ewe	Ewe
Iimeko zemisipha	Ewe	Ewe
Isifo sokuqina kwemihlathi	Ewe	Ewe
Fibromyalgia	Ngaphandle kwelebheli	Ngaphandle kwelebheli
Imigraines	Ngaphandle kwelebheli	Ngaphandle kwelebheli

Ngaba iZanaflex okanye iFlexeril isebenza ngakumbi?

I-Zanaflex kunye ne-Flexeril zozibini iziyobisi ezisebenzayo zokuqaqanjelwa yimisipha kunye nentlungu yomzimba. Ukusetyenziswa kwabo kuxhomekeke ekubeni yeyiphi efanelekileyo ngakumbi kwimeko-ngamatyala. Okwangoku, akukho datha yeklinikhi ibonisa ukuthelekisa ngokuthe ngqo phakathi kwala machiza mabini.

Ngokwe- Uhlalutyo lweemeta , I-cyclobenzaprine ifundwe kwezona zilingo zininzi zinobungqina bokuxhasa ukusetyenziswa kwayo. I-Tizanidine yaboniswa ukuba iyasebenza ekuthambekeni ngenxa yesifo sokuqina kwemithambo. Zombini i-cyclobenzaprine kunye ne-tizanidine zifunyenwe zisebenza kwiimeko ze-musculoskeletal ezifana nentamo ebukhali okanye iintlungu zomqolo.

Uhlalutyo lwe-meta kuvavanywa ngaphezulu kwe-100 yezilingo ezahlukeneyo ngokuthelekisa izihlunu ezahlukeneyo zokuphumla, kubandakanya iLioresal (baclofen), iSoma (carisoprodol), Robaxin (methocarbamol), Skelaxin (metaxalone), kunye neValium (diazepam). Ngokubanzi, uphononongo lufumanise ukuba la machiza ayathelekiswa nokusebenza kunye nokhuseleko. Ezinye izikhokelo zibonisa ukuba ukuphumla kwezihlunu kubangela ukwanda kobuthongo kwaye kufuneka isetyenziswe ixesha elifutshane kuphela.

Iziyobisi ezinje ngeZanaflex kunye neFlexeril zihlala zicetyiswa kunye nonyango lomzimba ukunciphisa iintlungu. Nxibelelana nomboneleli wezempilo ukumisela olona nyango lulungileyo onokulufumana.

Ukufunda kunye nokuthelekisa iindleko kweZanaflex vs.Flexeril

I-generic Zanaflex ihlala igutyungelwe luninzi lwezonyango kunye nezicwangciso zeinshurensi. Ubungakanani obumiselweyo buya kwahluka ngokuxhomekeka kumandla amayeza kunye nemiyalelo kagqirha wakho. Ixabiso eliphakathi lokuthengisa iZanaflex lijikeleze i- $ 56. Ngekhuphoni lesaphulelo seZanaflex, iindleko zentengiso zingangaphantsi kweedola ezili-10 nge-30, 4 iipilisi ze-mg.

I-Flexeril ikwagutyungelwe luninzi lwezonyango kunye nezicwangciso zeinshurensi xa imiselwe njenge-generic. Amacwecwe okukhululwa kwangoko aqhele ukumiselwa ukuba athathwe amaxesha ngamaxesha. Ixabiso eliphakathi lokuthengisa iyeza le-cyclobenzaprine linokuqhuba nge- $ 42. Unokuphinda usebenzise eli phetshana leFlexeril ukufumana amaxabiso ancitshisiweyo angama- $ 7 kwikhemesti ethatha inxaxheba.

	Zanaflex	Flexeril
Ngokuqhelekileyo ihlawulwa yi-inshurensi?	Ewe	Ewe
Ngokuqhelekileyo igutyungelwe yiMedicare?	Ewe	Ewe
Umthamo osemgangathweni	4 mg ithebhulethi rhoqo kwiiyure ezi-6 ukuya kwezi-8	10 mg tablet kathathu yonke imihla
I-Medicare copay eqhelekileyo	$ 0- $ 41	$ 1- $ 35
Ixabiso elilodwa	$ 9 +	$ 7 +

Fumana ikhuphoni kagqirha

Iziphumo eziqhelekileyo ezichaphazelekayo zeZanaflex vs Flexeril

Iziphumo eziqhelekileyo zeZanaflex zibandakanya umlomo owomileyo, ukozela, isiyezi, ukuba buthathaka kwezihlunu okanye ukudinwa, kunye ukuqhina . Ezinye iziphumo ebezingalindelekanga ezichaziweyo zibandakanya usulelo lomchamo womchamo (UTIs) kunye nentshukumo yokungazibandakanyi (i-dyskinesia).

Iziphumo eziqhelekileyo ezichaphazela uFlexeril zibandakanya ukozela, umlomo owomileyo, intloko ebuhlungu, ukudinwa kunye nesiyezi. I-Flexeril ikwabizwa ngokuba ibangela ezinye iziphumo ebezingalindelekanga ezinjengokuqunjelwa kunye nobucaphucaphu.

	Zanaflex	Flexeril
Imiphumela	Iyasebenza?	Rhoqo	Iyasebenza?	Rhoqo
Ukozela	Ewe	Iipesenti ezingama-48	Ewe	29%
Umlomo owomileyo	Ewe	49%	Ewe	amashumi amabini ananye%
Intloko ebuhlungu	Hayi	-	Ewe	5%
Ukudinwa	Ewe	41%	Ewe	6%
Ukuba nesiyezi	Ewe	16%	Ewe	1% -3%
Isicaphucaphu	Hayi	-	Ewe	1% -3%
Ukuqunjelwa	Ewe	4%	Ewe	1% -3%
I-DWS	Ewe	10%	Hayi	-
Iintshukumo zokuzibandakanya	Ewe	3%	Hayi	-

Olu alunakuba luluhlu olupheleleyo lweziphumo ezibi ezinokwenzeka. Nceda ujonge ugqirha wakho okanye umboneleli wezempilo ukuze ufunde okungakumbi.
Umthombo: DailyMed ( Zanaflex ), Yonke imihla ( Flexeril )

Ukudibana kweziyobisi kweZanaflex vs Flexeril

I-Zanaflex iqhutywa ikakhulu yi-CYP1A2 enzyme esibindini. Iziyobisi ezibhloka, okanye zithintele, le enzyme inokunyusa amanqanaba eZanaflex emzimbeni. Ukunyusa amanqanaba amachiza kunokukhokelela kwiziphumo ezibi njengokuwozela kunye nesiyezi. I-Zanaflex kufuneka ithintelwe nge-CYP1A2 inhibitors ezinje nge-ciprofloxacin kunye ne-cimetidine kunye neepilisi zokulawula ukuzalwa eziqukethe i-ethinyl estradiol.

I-Flexeril inokusebenzisana neziyobisi ze-serotonergic njenge iziyobisi kunye ne-MAO inhibitors. Ukuthatha la machiza ngeFlexeril kunokunyusa umngcipheko we-serotonin syndrome, imeko efuna unyango kwangoko.

Zombini iZanaflex kunye neFlexeril zinokunxibelelana neziyobisi ezinazo Uxinzelelo lwe-CNS iziphumo. Ezi ntlobo zeziyobisi zibandakanya i-barbiturates, i-opioids, kunye ne-benzodiazepines. I-Zanaflex kunye ne-Flexeril zinokuphucula iziphumo zazo kwaye zikhokelele ekunyukeni kwesiyezi kunye nokuthamba.

Iziyobisi	Iklasi yeziyobisi	Zanaflex	Flexeril
Ciprofloxacin Cimetidine IFluvoxamine Icycylovir Ticlopidine	CYP1A2 inhibitors	Ewe	Hayi
I-Ethinyl estradiol Indawo encinci I-Levonorgestrel	Izinto zokucwangcisa ngomlomo	Ewe	Hayi
Isocarboxazid IPhenelzine I-Tranylcypromine	I-Monoamine oxidase inhibitors (i-MAOIs)	Hayi	Ewe
Amitriptyline Umgca weNortriptyline Clomipramine	I-Tricyclic yoxinzelelo	Hayi	Ewe
IPhenobarbital IPentobarbital Indawo yokuhlala	IiBarbiturates	Ewe	Ewe
Oxycodone IHydrocodone I-Tramadol	Iipioids	Ewe	Ewe
IAlprazolam ILorazepam Diazepam	IiBenzodiazepines	Ewe	Ewe

* Qhagamshelana neengcali zonyango malunga nolunye unxibelelwano lweziyobisi

Izilumkiso zeZanaflex kunye neFlexeril

I-Zanaflex inokubangela i-hypotension okanye uxinzelelo lwegazi ngokungaqhelekanga. Esi siphumo sibonakala njenge i-hypotension ye-orthostatic eyenzeka xa umntu esiya kwindawo ethe tye emva kokulala phantsi. Kwimithamo engaphezulu, iFlexeril yaziwa ngokuba ibangela utshintsho kuxinzelelo lwegazi.

I-Zanaflex inokubangela ukulimala kwesibindi kwabanye abantu, ngakumbi abo banembali yokukhubazeka kwesibindi. I-Flexeril kufuneka isetyenziswe ngononophelo kubantu abaneengxaki zesibindi.

UFlexeril uyaziwa ukuba unobangela isifo se-serotonin , ngakumbi xa zithathwa ngoxinzelelo oluthile, ii-MAO inhibitors kunye neeopioid. Iimpawu kunye neempawu zesifo se-serotonin kufuneka zijongwe xa uqala unyango nge-Flexeril.

Imibuzo ebuzwa rhoqo malunga neZanaflex vs Flexeril

Yintoni iZanaflex?

I-Zanaflex, okanye i-tizanidine, sisixhobo sokuphumla esisisihlunu esisetyenziselwa ukunyanga ukuqaqamba kwemisipha ngenxa yokuqina kwesclerosis kunye nokwenzakala kwethambo lomqolo. Isebenza ngokuthintela imiqondiso phakathi kweemoto zemoto ukukhulula ithoni yezihlunu. Ihlala ithathwa njenge-2 mg okanye 4 mg ithebhulethi rhoqo kwiiyure ezintandathu ukuya kwezisibhozo.

Yintoni iFlexeril?

I-Flexeril ligama lophawu lwecyclobenzaprine. Sisihlunu esihlaziyayo esibonisiweyo ngenxa yeemeko ezibi, ezibuhlungu zemisipha ezinjengentamo okanye iintlungu zomqolo. Isebenza kwinkqubo ye-nervous central (CNS) yokuphelisa iintlungu zemisipha kunye ne-spasms. I-cyclobenzaprine iyafumaneka kwifom yokukhutshwa kwangoko kunye neefomu zokukhululwa ezandisiweyo.

Ngaba iZanaflex kunye neFlexeril ziyafana?

IZanaflex kunye neFlexeril azifani. I-Zanaflex ine-half-life ye-2.5 iiyure ngelixa i-Flexeril ine-half-life ye-18 iiyure ngokuphakathi. I-Zanaflex iza kuphela kwiipilisi zomlomo ezikhutshwa kwangoko kunye neepilisi njengeFlexeril iza nepilisi eyandisiweyo.

Ngaba iZanaflex okanye iFlexeril ibhetele?

I-Zanaflex sisiyobisi esitsha esivunyiweyo se-FDA esivunyiweyo sokuqina kwemisipha ngenxa ye-multiple sclerosis kunye nokulimala kwentambo yomqolo. I-Flexeril sisiyobisi esidala esiye safundisisa kakhulu iintlungu ze-musculoskeletal kunye ne-spasms. Iyeza elingcono lelona lisebenza ngcono kwimeko yakho. Nxibelelana nogqirha ukukunceda ufumane olona khetho lulungileyo.

Ndingayisebenzisa iZanaflex okanye iFlexeril ngelixa ndikhulelwe?

Zanaflex inokuba yingozi kusana olungekazalwa ngokwezifundo zezilwanyana. Akukhange kubekho silwanyana saneleyo okanye izifundo zabantu ezibonisa ukuba iFlexeril iyingozi ngelixa ukhulelwe. Ukuphumla kwezihlunu kufanele kusetyenziswe kuphela ukuba kukho izibonelelo ezicacileyo ezingaphezulu komngcipheko onokubakho. Funa ingcebiso kwezonyango kumboneleli wakho wokhathalelo lwempilo ngeendlela zonyango xa ukhulelwe.

Ndingazisebenzisa iZanaflex okanye iFlexeril ngotywala?

Ukusela utywala ngelixa uthatha iZanaflex okanye iFlexeril kunokunyusa iziphumo zokuthomalalisa la machiza. Akukhuthazwa ngokubanzi ukuba usele utywala kunye nezihlisi zezihlunu.

Ngaba i-tizanidine ingcono kune-cyclobenzaprine?

I-Tizanidine inokukhethwa ngenxa ye-muscle spasms ebangelwa yi-multiple sclerosis, i-cerebral palsy kunye nokulimala kwethambo lomqolo. ICyclobenzaprine isetyenziswa kunye ulungiso lwenyama kunye nokuphumla ukunciphisa iintlungu kunye nokuqaqamba kwemisipha.

Ngaba iZanaflex iyakhobokisa?

I-Zanaflex ayisiyonto ilawulwayo ngokwe-DEA. Nangona kunjalo, njengezinye izinto eziphumza izihlunu, inokusetyenziswa gwenxa ngabanye abantu. I-Zanaflex ithathwa njengenyango yokhetho lwexesha elifutshane. Ukuphathwa gadalala kwaye ukuxhomekeka kunokwenzeka ngokusetyenziswa kwexesha elide kwaye kukhokelele kwimikhwa yokulutha.

Ngaba iFlexeril iyanceda ngeentlungu?

I-Flexeril inokuphazamisa ngokungathanga ngqo iintlungu ezinxulunyaniswa ne-spasms yemisipha. Kuxhomekeke kwinto ebangela iintlungu, ugqirha wakho unokuqala ukucebisa ichiza elingaphezulu kwekhawuntara njenge acetaminophen okanye ibuprofen .