ICymbalta vs Effexor: Umahluko, ukufana, kwaye kukuphi okungcono kuwe
Iziyobisi Vs. UmhloboUkujonga ngokubanzi iziyobisi kunye nolwahluko ophambili | Imiqathango inyangwa | Ukusebenza | Ukuhlawulwa kwe-inshurensi kunye nokuthelekiswa kweendleko | Imiphumela | Ukusebenzisana kweziyobisi | Izilumkiso | FAQ
ICymbalta (duloxetine) kunye ne-Effexor (venlafaxine) ngamagama anegama lebrendi elisetyenziselwa ukunyanga iimeko zengqondo ezinje ngoxinzelelo noxinzelelo. Zihlala zichazwe njenge-anti-depressants ukunceda ukukhulula iimpawu zesifo sokudakumba. Iimpawu zoxinzelelo olukhulu lokudakumba zinokubandakanya ukudana okungapheliyo kunye nelahleko enkulu yomdla kwimisebenzi yemihla ngemihla.
ICymbalta kunye ne-Effexor bobabini bakudidi lweziyobisi ezibizwa ngokuba yi-serotonin kunye ne-norepinephrine reuptake inhibitors (SNRIs). Basebenza ngokwandisa ukubakho kwe-serotonin kunye ne-norepinephrine kwingqondo. Ezi khemikhali, okanye ii-neurotransmitters, kukholelwa ukuba zidlala indima ekwenzekeni kokuphazamiseka kwengqondo.
Ngeenjongo zolu thelekiso, igama i-Effexor linokubhekisa kwi-Effexor XR, ekukuphela kwayo enegama lophawu lwe-Effexor olufumanekayo ngoku kwintengiso.
Nguwuphi umahluko ophambili phakathi kweCymbalta kunye ne-Effexor?
ICymbalta
ICymbalta ligama lophawu lwe-duloxetine. Iyafumaneka njengomlomo okhawulezileyo-ukukhutshwa kwecapsule ngamandla e-20 mg, 30 mg, okanye 60 mg. Ihlala ichithwe njengepilisi enye ngomlomo kube kanye yonke imihla kuxhomekeka kwimeko yokunyangwa. Elona thamo liphezulu ngosuku yi-120 mg nangona kungekho bungqina bokuba iidosi mkhulu kune-60 mg Nika ukwanda okubonakalayo kwinzuzo.
ICymbalta inehafu yobomi ejikeleze iiyure ezili-12. Isisiseko sokucoca umzimba kunye nokususa isibindi kunye nezintso. Ukusetyenziswa kwayo kufuneka kuthintelwe kwabo banesifo esibi okanye ukukhubazeka kwezintso.
Umncedisi
I-Effexor ligama lophawu lwe-venlafaxine. Nangona kunjalo, igama lophawu lwe-Effexor lufumaneka kuphela njenge-Effexor XR, okanye i-venlafaxine iipilisi zokukhupha ezandisiweyo. Ukukhutshwa kwangoko i-Effexor kuyekisiwe kuba kufuneka kutsalwe amaxesha ngamaxesha emini kwaye kubangele isicaphucaphu ngakumbi kunohlobo olukhutshiweyo.
I-Effexor XR iza ngeephilisi zomlomo kunye namandla e-37.5 mg, 75 mg, kunye ne-150 mg. Umthamo unokwahluka ngokuxhomekeke kwimeko yokuphathwa. Nangona kunjalo, i-Effexor XR ihlala ithathwa kube kanye yonke imihla ngethamo lemihla ngemihla ekujoliswe kulo le-75 mg kunye nedosi ephezulu yemihla ngemihla ye-225 mg.
NjengeCymbalta, i-Effexor i-metabolism kwisibindi kwaye inesiqingatha sobomi bayo ukuya kwiiyure ezili-11 . Ingasetyenziselwa kwabo banesibindi okanye ukukhubazeka kwezintso ukuba kuthathwa iidosi ezisezantsi.
| Umahluko ophambili phakathi kweCymbalta kunye ne-Effexor | ||
|---|---|---|
| ICymbalta | Umncedisi | |
| Iklasi yeziyobisi | I-Serotonin kunye ne-norepinephrine reuptake inhibitor (SNRI) | I-Serotonin kunye ne-norepinephrine reuptake inhibitor (SNRI) |
| Uhlobo lweBrith / generic | Ibhranti kunye nohlobo oluqhelekileyo olukhoyo | Ibhranti kunye nohlobo oluqhelekileyo olukhoyo |
| Ngubani igama eliqhelekileyo? | Duloxetine | IVenlafaxine |
| Zeziphi iifom eza nalo iziyobisi? | I-capsule yomlomo, ukukhutshwa kwexesha elide | I-capsule yomlomo, ukukhutshwa kwexesha elide |
| Ithini idosi esemgangathweni? | 60 mg kanye yonke imihla | 75 mg kanye yonke imihla |
| Lude kangakanani unyango oluqhelekileyo? | Ixesha elide | Ixesha elide |
| Ngubani oqhelekileyo usebenzisa amayeza? | Abantu abadala kunye nolutsha | Abantu abadala kunye nolutsha |
Imiqathango ephathwa yiCymbalta kunye ne-Effexor
ICymbalta yi-FDA evunyiweyo yokunyanga isifo sokudakumba (MDD) kunye noxinzelelo ngokubanzi (GAD). Ingasetyenziselwa ukunyanga iintlungu ezivela kwi-fibromyalgia kunye neswekile ye-neuropathy, kunye nentlungu ngokubanzi kwimisipha, imisipha, iigaments kunye namathambo. ICymbalta ngamanye amaxesha inokusetyenziselwa ngaphandle kwelebheli kwezinye iingxaki zoxinzelelo.
I-Effexor XR yi-FDA evunyiweyo yokunyanga isifo esikhulu soxinzelelo (MDD), isifo soxinzelelo ngokubanzi (GAD), uxinzelelo lwentlalo (SAD), kunye panic disorder (PD). Ngamanye amaxesha kusetyenziswa iilebheli ezinganyangekiyo ukunyanga ukuphazamiseka okungafunekiyo (OCD), ukuphazamiseka kwangaphambi kokuya exesheni (PMDD), kunye nentlungu.
| Imeko | ICymbalta | Umncedisi |
| Uxinzelelo olukhulu lokudakumba | Ewe | Ewe |
| Ukuphazamiseka koxinzelelo ngokubanzi | Ewe | Ewe |
| Ukuphazamiseka koxinzelelo kwezentlalo | Ngaphandle kwelebheli | Ewe |
| Ukuphazamiseka kovalo | Ngaphandle kwelebheli | Ewe |
| Intlungu yeswekile yesifo se-neuropathic | Ewe | Ngaphandle kwelebheli |
| Fibromyalgia | Ewe | Ngaphandle kwelebheli |
| Intlungu engapheliyo yesifo semisipha | Ewe | Ngaphandle kwelebheli |
| Ubume obungalunganga obuphambanisayo | Hayi | Ngaphandle kwelebheli |
| Ukuphazamiseka kwangaphambi kokuya exesheni | Hayi | Ngaphandle kwelebheli |
Ngaba iCymbalta okanye i-Effexor iyasebenza ngakumbi?
Ukusebenza kweCymbalta okanye i-Effexor kuxhomekeke kwimeko yokuphathwa. Zimbalwa kakhulu izifundo ezithelekise ngokuthe ngqo iCymbalta kunye ne-Effexor. Nangona kunjalo, xa kuthelekiswa ne-placebo, iCymbalta kunye ne-Effexor zombini zisebenza ngakumbi ekunyangeni iimeko ezinje ngoxinzelelo olukhulu.
Olunye uphononongo lwadibanisa izilingo ezininzi zeklinikhi kwaye kwafunyaniswa ukuba i-venlafaxine ibhetele ukhetho lwethutyana yoxinzelelo olukhulu kune-duloxetine. I-Venlafaxine, isithako esisebenzayo se-Effexor, sinokukhethwa kwabo bangaphenduli kakuhle kunyango lokuqala nge-serotonin reuptake inhibitors (SSRIs) okanye i-tricyclic antidepressants (TCAs). Nangona kunjalo, uphononongo lufumanise ukuba akukho mahluko ubalulekileyo kwimpendulo kunye nenqanaba lokuphendula phakathi kwe-duloxetine kunye ne-venlafaxine.
Olunye uphononongo olucwangcisiweyo thelekisa i-venlafaxine, i-duloxetine, kunye nezinye i-anti-depressants Njengeparoxetine, i-fluoxetine, kunye ne-fluvoxamine. Xa kuthelekiswa nezinye iindlela, i-venlafaxine yafunyanwa njengenye ye-anti-depressants esebenzayo. Nangona kunjalo, zombini i-venlafaxine kunye ne-duloxetine babekwa njengolunye lwezinto zokunyanga uxinzelelo oluncinci, ngokubhekisele kwiziphumo ebezingalindelekanga.
Nxibelelana nomboneleli wezempilo ojolise kunyango lweyona ndlela yokonyango ilungileyo.
Umyinge kunye nokuthelekiswa kwexabiso leCymbalta vs.Exexexor
ICymbalta ligama lonyango elichaza uxinzelelo kuxinzelelo. Inguqulelo yohlobo oluqhelekileyo, i-duloxetine, ihlala ihlawulwa yi-Medicare kunye nezicwangciso zeinshurensi. Ukubonelelwa ngeentsuku ezingama-30, ixabiso eliphakathi lokuthengisa linokungaphezulu kwe- $ 470. Ngekhuphoni ye-SingleCare Cymbalta, amaxabiso ohlobo oluqhelekileyo aqala kwi- $ 15 kwii-pharmacy ezithatha inxaxheba.
Amacwecwe e-Effexor XR ayafumaneka xa kuthengwa ngugqirha. Iitafile zeGeneric Effexor XR zihlala zigutyungelwa yiMedicare kunye nezicwangciso zeinshurensi. Ngamaxabiso aphakathi kwe- $ 145, i-Effexor XR yexabiso eliphantsi kuneCymbalta. Nangona kunjalo, ukusebenzisa isigqebhezana se-Effexor XR kwi-SingleCare kunokuzisa iindleko ezantsi nangakumbi. Buza usokhemesti wakho ukuba enze igeneric aze ayifumane malunga ne- $ 15.
| ICymbalta | Umncedisi | |
| Ngokuqhelekileyo ihlawulwa yi-inshurensi? | Ewe | Ewe |
| Ngokuqhelekileyo ihlanganiswe yiCandelo le-Medicare? | Ewe | Ewe |
| Ubungakanani | Iipilisi ezingama-30 | Iipilisi ezingama-30 |
| I-Medicare copay eqhelekileyo | $ 0- $ 89 | $ 0- $ 1 |
| Ixabiso elilodwa | $ 15 + | $ 15 + |
Iziphumo eziqhelekileyo zeCymbalta vs Effexor
Iziphumo zixhaphakileyo zeCymbalta zibandakanya isicaphucaphu, intloko ebuhlungu, umlomo owomileyo, ukudinwa okanye ukozela, ukuqhina, nokudinwa. ICymbalta inokubangela urhudo, ukuncipha kokutya, ukubila, kunye nentlungu esiswini, phakathi kwezinye iziphumo ebezingalindelekanga.
Iziphumo eziqhelekileyo ezichaphazelekayo ze-Effexor isicaphucaphu, intloko ebuhlungu, umlomo owomileyo, ubuthathaka kunye nokuqaqanjelwa sisisu. I-Effexor inokubangela ukulala, ukuqunjelwa, isiyezi, urhudo, kunye nokunciphisa ukutya.
Zombini iCymbalta kunye ne-Effexor zinokubangela ukwehla kwesondo (libido). Nangona kunjalo, i-Effexor ibonakalisiwe ukuba ibangela iingxaki zokungasebenzi kakuhle ngokwesondo kuneCymbalta.
Jonga itheyibhile engezantsi yezinye iziphumo ebezingalindelekanga eziqhelekileyo zeCymbalta kunye ne-Effexor.
| ICymbalta | Umncedisi | |||
| Imiphumela | Iyasebenza? | Rhoqo | Iyasebenza? | Rhoqo |
| Isicaphucaphu | Ewe | 2. 3% | Ewe | 4% |
| Intloko ebuhlungu | Ewe | 14% | Ewe | Mbini% |
| Umlomo owomileyo | Ewe | 13% | Ewe | Shumi elinantlanu% |
| Ukozela | Ewe | 10% | Ewe | Mbini% |
| Ubuthathaka | Hayi | - | Ewe | Mbini% |
| Ukudinwa | Ewe | 9% | Hayi | - |
| Ukuphuthelwa | Ewe | 9% | Ewe | Mbini% |
| Ukuqunjelwa | Ewe | 9% | Ewe | 9% |
| Ukuba nesiyezi | Ewe | 9% | Ewe | 16% |
| Urhudo | Ewe | 9% | Ewe | 8% |
| Ukunciphisa ukutya | Ewe | 7% | Ewe | * |
| Ukwanda kokubila | Ewe | 6% | Ewe | 1% |
| Intlungu zesisu | Ewe | 5% | Ewe | * |
| Ukuncipha kwe-libido | Ewe | 3% | Ewe | 5% |
| Umbono ongaqhelekanga | Ewe | 3% | Ewe | 4% |
| Ukubetha kwentliziyo | Ewe | Mbini% | Ewe | Mbini% |
* akuxelwa
Ukuphindaphinda akusekelwanga kwidatha ukusuka kuvavanyo lwentloko ukuya entloko. Olu alunakuba luluhlu olupheleleyo lweziphumo ezibi ezinokwenzeka. Nceda ujonge ugqirha wakho okanye umboneleli wezempilo ukuze ufunde okungakumbi.
Umthombo: DailyMed ( ICymbalta ), Yonke imihla ( Umncedisi )
Ukudibana kweziyobisi neCymbalta vs.Expexor
ICymbalta kunye ne-Effexor akufuneki zisetyenziswe kunye ne-monoamine oxidase inhibitors (MAOIs) enje nge selegiline kunye ne phenelzine. ICymbalta okanye iEffexor akufuneki isetyenziswe kwiintsuku ezili-14 zokuyekiswa kwe-MAOI. Ngaphandle koko, kukho umngcipheko okhulayo we-serotonin syndrome, imeko enzima enokuthi ifune unyango olungxamisekileyo.
Kunokubakho umngcipheko wesifo se-serotonin xa iCymbalta okanye i-Effexor ithathwa ecaleni kwesinye isiyobisi se-serotonergic. Iziyobisi zeSerotonergic zibandakanya i-serotonin reuptake inhibitors ekhethiweyo (i-SSRIs) kunye ne-tricyclic antidepressants (TCAs). Isilumkiso kufuneka sisetyenziswe xa usebenzisa iziyobisi ze-serotonergic ngeCymbalta okanye i-Effexor.
Iziyobisi ezinjengeparoxetine okanye i-fluoxetine zinokuphazamisa imetabolism yeCymbalta kunye nokunyusa amanqanaba egazi. Oku kunokukhokelela kumngcipheko okhulayo weziphumo ebezingalindelekanga ezibi kunye neCymbalta.
I-cymbalta kunye ne-Effexor kufuneka zisetyenziswe ngononophelo okanye zithintelwe ngamachiza anxamnye nokuvuvukala (ii-NSAID) kunye nee-anticoagulants. Ukusebenzisa la mayeza kunye kunokunyusa umngcipheko wokopha.
| Iziyobisi | Iklasi yeziyobisi | ICymbalta | Umncedisi |
| Selegiline IPhenelzine I-Rasagiline | I-Monoamine oxidase inhibitors (i-MAOIs) | Ewe | Ewe |
| Paroxetine Sertraline IFluoxetine | Ukukhetha i-serotonin reuptake inhibitors (i-SSRIs) | Ewe | Ewe |
| Amitriptyline Clomipramine Umgca weNortriptyline | I-Tricyclic antidepressants (TCAs) | Ewe | Ewe |
| I-Aspirin Ibuprofen INaproxen Diclofenac | Izidakamizwa ezichasayo ezichasayo (i-NSAID) | Ewe | Ewe |
| IWarfarin | Iintsholongwane | Ewe | Ewe |
Nxibelelana noochwephesha kwezolunye unxibelelwano olunokubakho ngeziyobisi
Izilumkiso zeCymbalta kunye ne-Effexor
Ukusilela kwesibindi kuye kwabikwa ngokusetyenziswa kweCymbalta. Kulawo anembali yokusetyenziswa gwenxa kotywala okanye ukungasebenzi kwesibindi, iCymbalta kufuneka ithintelwe. Ukusetyenziswa kweCymbalta kufuneka kuyekwe kwabo bakhulisa iimpawu zokungaphumeleli kwesibindi, njenge-jaundice.
Ukusetyenziswa kweCymbalta okanye i-Effexor kuthwala umngcipheko wesifo se-serotonin, esenzeka xa kukho ukugqitha kwe-serotonin kwingqondo. Iimpawu zeserotonin syndrome zinokubandakanya ukubetha kwentliziyo ngokukhawuleza, ukonyuka koxinzelelo lwegazi, ukubila, ukungcangcazela kunye nomkhuhlane.
ICymbalta kunye ne-Effexor zinokubangela ukonyuka koxinzelelo lwegazi. Abo banembali yoxinzelelo lwegazi oluphezulu kufuneka babekwe esweni ngelixa kunyango ngeCymbalta okanye i-Effexor.
ICymbalta kunye ne-Effexor kufuneka zisetyenziswe ngononophelo kwabo banembali yokuphazamiseka kwengqondo okanye ukuxhuzula. Ezi ziyobisi zinokuvula i-mania, hypomania, okanye ukubanjwa kwabanye abantu.
Qhagamshelana nomboneleli wezempilo malunga nezinye izilumkiso kunye nezilumkiso ngeCymbalta kunye ne-Effexor.
Imibuzo ebuzwa rhoqo malunga neCymbalta vs Effexor
Yintoni iCymbalta?
ICymbalta ligama lophawu lwe-duloxetine. Isetyenziselwa unyango lwexinzelelo kunye noxinzelelo. Isetyenziselwa ukunyanga iintlungu zesifo seswekile kunye ne-fibromyalgia. ICymbalta iyafumaneka kwiicapsule ezandisiweyo ezikhutshiweyo kumandla we-20 mg, 30 mg, okanye 60 mg.
Yintoni i-Effexor?
I-Effexor ligama le-venlafaxine. Isetyenziselwa unyango lokudakumba okukhulu, ukuphazamiseka koxinzelelo ngokubanzi, ukuphazamiseka koxinzelelo kwezentlalo, kunye noxinzelelo lokuphakuzela. Rhoqo i-Effexor iyekile; Nangona kunjalo, iipilisi ze-Effexor XR ziyafumaneka kumandla angama-37.5 mg, ama-75 mg, kunye ne-150 mg.
Ngaba iCymbalta kunye ne-Effexor ziyafana?
ICymbalta kunye ne-Effexor zombini ziyi-serotonin kunye ne-norepinephrine reuptake inhibitors (SNRIs). Kodwa azikho ichiza elifanayo. Ukongeza ekunyangeni uxinzelelo olukhulu kunye noxinzelelo, iCymbalta ikwayi-FDA evunyiweyo yokunyanga iintlobo ezithile zentlungu yesifo. Kwelinye icala, i-Effexor yi-FDA evunyiweyo yokunyanga uloyiko kunye noxinzelelo lwentlalo.
Ngaba iCymbalta okanye i-Effexor ibhetele?
I-anti-depressant engcono ixhomekeke kwimeko yokuphathwa kunye namanye amayeza umntu anokuwathatha. IVenlafaxine inokuba yeyona ndlela isebenzayo yokunyanga ixeshana. Nangona kunjalo, inokuba nokunyamezeleka okuncinci kuneCymbalta ngokwempembelelo yecala, njengokungasebenzi kakuhle ngokwesondo.
Ndingayisebenzisa iCymbalta okanye i-Effexor ngelixa ndikhulelwe?
Akukho zifundo ziqinisekileyo zibonise ukuba iCymbalta okanye i-Effexor inokukhuseleka ngexesha lokukhulelwa. I-anti-depressant kufuneka isetyenziswe kuphela ngexesha lokukhulelwa ukuba izibonelelo zingaphezulu komngcipheko onokubakho. Ngamanye amaxesha, iCymbalta okanye i-Effexor inokufuna ukusetyenziselwa ukulawula iimpawu zoxinzelelo ngexesha lokukhulelwa. Nxibelelana nomboneleli wezempilo ngengcebiso yonyango ngaphambi kokusebenzisa iCymbalta okanye iEffexor ngelixa ukhulelwe.
Ndingayisebenzisa iCymbalta okanye iEffexor ngotywala?
Utywala ngokumodareyitha bukhuselekile ngelixa uthatha iCymbalta okanye i-Effexor. Nangona kunjalo, ukusela utywala ngelixa uqala unyango ngeCymbalta okanye i-Effexor kunokubangela ukwanda kwesiyezi okanye ukozela. Unokucetyiswa ukuba uyeke ukusela utywala kude kube ziintsuku ezimbalwa emva kokuqala unyango.
Ngaba i-Effexor iyayichaphazela imemori?
Akukho bungqina bokuba i-Effexor ichaphazela ngqo inkumbulo. I-Effexor XR yaziwa ngokuba ibangela i-hyponatremia, okanye amanqanaba esodium ephantsi egazini, ngakumbi ukuba kuthathwa i-diuretics. Iimpawu kunye neempawu zehyponatremia zibandakanya intloko, ukudideka, kunye nokuphazamiseka kwememori. Ugqirha wakho unokucebisa ngokumisa i-Effexor XR de i-hyponatremia isombulule.
Yeyiphi enye indlela elungileyo kwiCymbalta?
ICymbalta yi-serotonin ekhethiweyo kunye ne-norepinephrine reuptake inhibitor (SNRI). Ezinye ii-SNRI zibandakanya i-Effexor (venlafaxine), IPristiq (desvenlafaxine) , kunye neSavella (milnacipran). Thetha nomboneleli wezempilo malunga nokukhetha unyango olunokuthintela uxinzelelo kuwe.
Kubi kangakanani ukurhoxiswa kwe-Effexor?
Idosi ye-Effexor kufuneka icothwe kancinci ukunceda ukuthintela iimpawu zokurhoxa. Ukuyekiswa ngesiquphe kwe-Effexor kungakhokelela kwiimpawu ezinje ngesicaphucaphu, isiyezi, ukugabha, amaphupha amabi, ukuba nochuku, kunye nentloko ebuhlungu. Iimpawu zokurhoxa ze-Effexor zinokubandakanya i-paresthesias, okanye ukuqaqamba kwesikhumba.
