Eyona >> Iziyobisi Vs. Umhlobo >> I-Wellbutrin vs.Chantix: Umahluko, ukufana, kwaye kukuphi okungcono kuwe

I-Wellbutrin vs.Chantix: Umahluko, ukufana, kwaye kukuphi okungcono kuwe

Iziyobisi Vs. Umhlobo

Siyavuyisana nawe — ugqibe ekubeni wenze njalo yeka ukutshaya ! Wenza isigqibo esikhulu kwimpilo yakho iyonke. Kwangoko, uxinzelelo lwegazi kunye nokubetha kwentliziyo yakho kuya kuncipha. Ngosuku nje olunye, umngcipheko wokuhlaselwa sisifo sentliziyo uya kuncipha. Ezinye izibonelelo zibandakanya i-cholesterol esezantsi, amathuba amancinci omhlaza wemiphunga , kunye namathambo omeleleyo kunye nenkqubo yomzimba yokuzikhusela.

Ngamanye amaxesha, kunzima ukuyeka ukutshaya uwedwa, kwaye ugqirha wakho usenokukhankanya ukusebenzisa amayeza kagqirha ukukunceda ungatshayi. Wellbutrin (bupropion hydrochloride) kunye neChantix (varenicline tartrate), eyenziwe yiPfizer, zimbini iziyobisi ezithandwayo ezisetyenziselwa ukunceda abaguli bayeke ukutshaya, kwaye zamkelwe yi-FDA yokuyeka ukutshaya. Nangona zisetyenziselwa injongo enye, zinomahluko omkhulu.

Nguwuphi umahluko ophambili phakathi kweWellbutrin kunye neCantix?

I-Wellbutrin yonyango oluchasayo olumiselweyo off-ileyibheli ukuyeka ukutshaya. Akucaci ukuba uWellbutrin usebenzela njani ukuyeka ukutshaya, kodwa siyazi ukuba iyanceda ukunciphisa inkanuko kwaye iyanciphisa neempawu zokurhoxa. Iyafumaneka kwithebhulethi ekhupha kwangoko (generic) kunye nokukhululwa okuzinzileyo (i-SR) kunye nokukhutshwa okwandisiweyo (XL). Iifomathi ze-SR kunye ne-XL zombini ziyafumaneka kwi-brand kunye ne-generic. I-SR imiselwa kabini ngemini kwaye i-XL imiselwa kube kanye ngemini.

I-Chantix yi-nicotinic agonist-incamathela kwii-nicotine receptors kwingqondo, ukuze i-nicotine ingabinakho. Iyafumaneka ngegama lophawu kwifom yeethebhulethi. Akukho nalinye ichiza elinenikotini.

Umahluko ophambili phakathi kweWellbutrin vs. Chantix
	Wellbutrin	Chantix
Iklasi yeziyobisi	I-Aminoketone yoxinzelelo	Uncedo lokuyeka ukutshaya uNicotinic
Uhlobo lweBrith / generic	Brand kunye generic	Igama lebrand
Ngubani igama eliqhelekileyo?	IBupropion	Uluhlu lweVarenicline
Zeziphi iifom eza nalo iziyobisi?	Ithebhulethi Ithebhulethi ye-SR (ukukhutshwa okuzinzileyo, kabini idosi yemihla ngemihla) Ithebhulethi yeXL (ukukhutshwa okwandisiweyo, idosi yemihla ngemihla)	Ithebhulethi
Ithini idosi esemgangathweni?	Qala iveki enye ngaphambi kokutshaya usuku lokuyeka ukutshaya: I-150 mg SR mihla le ngeentsuku ezi-3, emva koko i-150 mg SR kabini kabini ngemini	Qala iveki enye ngaphambi kokutshaya usuku lokuyeka ukutshaya: 0.5 mg yonke imihla ngeentsuku ezi-3, emva koko i-0.5 mg kabini yonke imihla ngeentsuku ze-4, emva koko i-1 mg kabini yonke imihla emva koko
Lude kangakanani unyango oluqhelekileyo?	Iyahluka	Iiveki ezili-12, zinokuqhubeka nezinye iiveki ezili-12
Ngubani oqhelekileyo usebenzisa amayeza?	Abantu abadala	Abantu abadala

Iimeko eziphathwe yi-Wellbutrin vs. Chantix

I-Wellbutrin imiselwe ngaphandle kwelebheli njengoncedo ekuyekeni ukutshaya unyango. I-Wellbutrin inokumiselwa kunye okanye ngaphandle kwonyango lwe-nicotine (NRT). Ukufakwa endaweni yeNicotine kunokusetyenziswa ngohlobo lwe-nicotine patch okanye i-lozenge, umzekelo, kunye kunye ne-Wellbutrin, iminqweno yakho ye-nicotine kufuneka yehle.

I-Wellbutrin (zonke iifom) ibonakalisiwe kwisifo sokudakumba. I-Wellbutrin XL ikwabonakalisiwe kwisifo esichaphazeleka ngokwamaxesha onyaka. I-Wellbutrin ineentlobo ngeentlobo zokusetyenziswa kwelebheli, ezichazwe kwitshathi engezantsi.

Usenokuba ukhe weva malunga Zyban , equlethe eyona nto isebenzayo (bupropion) njengeWellbutrin. UZyban ubonakalisiwe ukusetyenziswa kunyango lokuyeka ukutshaya. I-Wellbutrin ihlala isetyenziselwa ukuyeka ukutshaya, nangona kungaboniswanga ngokusemthethweni ngenxa yesi sizathu. Ulwazi olumiselweyo ithi , I-Wellbutrin SR ayivunyelwanga unyango lokuyeka ukutshaya; Nangona kunjalo, iqulethe into efanayo esebenzayo njengeyeza lokuyeka ukutshaya iZyban. Nangona kunjalo, oogqirha bahlala bemisela iWellbutrin ngokuyeka ukutshaya ngeenjongo zokugubungela i-inshurensi.

I-Chantix ibonakalisiwe ngonyango lokuyeka ukutshaya. I-Chantix akufuneki ithathwe kunye ne-NRT kuba inokubangela ukonyuka isicaphucaphu, ukugabha, intloko ebuhlungu, isiyezi, isisu esibuhlungu nokudinwa.

Imeko	Wellbutrin	Chantix
Uncedo ekuyekeni ukutshaya unyango	Ngaphandle kwelebheli	Ewe
Ukuphazamiseka okukhulu koxinzelelo (ukukhutshwa kwangoko kwe-Wellbutrin, i-SR, i-XL)	Ewe	Hayi
Ukuphazamiseka kwexesha elithile (Wellbutrin XL)	Ewe	Hayi
I-ADHD	Ngaphandle kwelebheli	Hayi
Ukutyeba kakhulu	Ngaphandle kwelebheli	Hayi
Ukuxhuzula	Ngaphandle kwelebheli	Hayi
PTSD	Ngaphandle kwelebheli	Hayi
Ukoyikwa kwentlalo	Ngaphandle kwelebheli	Hayi
Ukungasebenzi kakuhle ngokwesondo	Ngaphandle kwelebheli	Hayi

Ngaba i-Wellbutrin okanye iCantix iyasebenza ngakumbi?

Ukhuseleko kunye nokusebenza kwe-bupropion kwafundwa ngeendlela ezininzi izilingo , usebenzisa i-bupropion ngohlobo lweZyban kunye nengcebiso. Kwisifundo seeveki ezisixhenxe, i-bupropion yaboniswa ukuba isebenze ngakumbi kune-placebo. Kwiinyanga ezintandathu, abaguli benze ngcono ekugcineni ukuyeka emva kokuphathwa nge-bupropion. Kwesinye isifundo, unyango nge-bupropion lwalusebenza ngakumbi ngakumbi kune-placebo, ukunciphisa umnqweno wokutshaya, kunye nokunciphisa iimpawu zokurhoxa (ezinjengokucaphuka, umsindo, kunye noxinzelelo).

Kuvavanyo lweklinikhi, uChantix wafunyanwa ukunciphisa umnqweno wokutshaya , ukunciphisa iimpawu zokurhoxa, kunye nokunceda abaguli bagcine ukungazinbi. Izifundo ezibini zithelekisa iChantix ukuya kwi-bupropion ukuya kwi-placebo kwiiveki ezili-12 kwaye izigulana zalandelwa iiveki ezingama-40 emva konyango. Kwisifundo esinye, iipesenti ezingama-44 zezigulane ezithatha i-Chantix ziyeke ukutshaya ngeveki 9 ukuya kwi-12, xa kuthelekiswa neepesenti ezingama-30 zezigulane ezithatha i-bupropion kunye ne-17% yezigulane ezithatha indawo ye-placebo. Olunye uphononongo lubonise iziphumo ezifanayo.

Izifundo zafumanisa ukuba omabini la machiza ayengcono kune-placebo, kwaye agqiba kwelokuba iChantix yayisebenza kancinci kuneZyban.

Omabini la machiza anokusebenza kakhulu kunyango lokuyeka ukutshaya, kodwa wonke umntu wahlukile kwindlela asabela ngayo kumayeza athile. Olona nyango lusebenzayo kuwe unokuchongwa ngugqirha wakho, onokujonga imeko yakho yezonyango kunye nembali, kunye namanye amayeza owathathayo anokusebenzisana neWellbutrin okanye iChantix.

Umyinge kunye neendleko zokuthelekisa i-Wellbutrin vs Chantix

I-Wellbutrin ihlala igutyungelwe yi-inshurensi kunye necandelo leMedicare D, kwifom yesiqhelo yebupropion. Ukucela imveliso enegama lophawu kuya kubiza kakhulu kwaye akunakugqunywa. Ngaphandle kwe-inshurensi, igama le-brand Wellbutrin SR lixabisa malunga ne-541 yeedola kunikezelo lwenyanga enye, ngelixa generic ixabisa iphantsi njenge- $ 15 ngekhuphoni ye-SingleCare.

I-Chantix ihlala igutyungelwe yi-inshurensi kunye ne-Medicare Part D. Ngaphandle kwe-inshurensi, ipakethi yenyanga yokuqala ye-Chantix ibiza phakathi kwe- $ 500- $ 600, kunye nepakethi yenyanga eqhubekayo ebiza ngaphantsi kwe- $ 450 ngokusebenzisa ikhadi lesaphulelo elilodwa.

	Wellbutrin	Chantix
Ngokuqhelekileyo ihlawulwa yi-inshurensi?	Ewe (i-generic; i-brand inokuba ne-copay ephezulu okanye ifune ugunyaziso lwangaphambili)	Ewe
Ngokuqhelekileyo ihlanganiswe yiCandelo le-Medicare?	Ewe (generic)	Ewe
Umthamo osemgangathweni	# 60, 150 mg iipilisi ze-SR	Ipakethe yokuqala yenyanga e-1 okanye Ipakethe yenyanga e-1 eqhubekayo
Uhlobo lweMedical Medicare Part D	$ 0- $ 47	$ 25- $ 578
Ixabiso elilodwa	Iidola ezili-15- $ 40	$ 450 +

Iziphumo eziqhelekileyo ezichaphazelekayo zeWellbutrin kunye neCantix

Iziphumo eziqhelekileyo ze-Wellbutrin zintloko, umlomo owomileyo, isicaphucaphu, ukulala, ukuqhina, kunye nesiyezi. Iziphumo eziqhelekileyo ezichaphazelekayo zeCantix zintloko, isisongela, ukulala, kunye namaphupha angaqhelekanga. Uya kufumana isikhokelo sonyango, ngolwazi malunga neziphumo ebezingalindelekanga, kunye nonyango olutsha okanye lokugcwalisa kwakhona lwe-Wellbutrin okanye iChantix. Ezinye iziphumo ezibi zinokwenzeka. Nxibelelana nomboneleli wakho wezempilo uluhlu olupheleleyo lweziphumo ebezingalindelekanga.

	Wellbutrin	Chantix
Imiphumela	Iyasebenza?	Rhoqo	Iyasebenza?	Rhoqo
Intloko ebuhlungu	Ewe	26%	Ewe	15-19% *
Umlomo owomileyo	Ewe	17%	Ewe	4-6%
Isicaphucaphu	Ewe	13%	Ewe	16-30%
Ukuqunjelwa	Ewe	10%	Ewe	5-8%
Ukuphelelwa ngumdla wokutya	Ewe	5%	Ewe	1-2%
Ukuphuthelwa / ingxaki yokulala	Ewe	Shumi elinanye%	Ewe	18-19%
Amaphupha angaqhelekanga / acacileyo	Hayi	N / A	Ewe	9-13%
Ukuba nesiyezi	Ewe	7%	Ewe	Ixelwe njengesiqhelo
Ukungcangcazela	Ewe	6%	Ewe	Ixelwe njengonqabileyo
Ixhala	Ewe	5%	Ewe	% ayixelwanga
Ukubila	Ewe	6%	Hayi	N / A
Irhashalala	Ewe	5%	Ewe	1-3%
Tinnitus	Ewe	6%	Ewe	Ixelwe njengonqabileyo

* Utshintsho ngokwedosiSource: DailyMed ( Wellbutrin ), Yonke imihla ( Chantix )

Ukudibana kweziyobisi zeWellbutrin vs.Chantix

Ngelixa i-Wellbutrin ingasetyenziswa ngokudibeneyo ne-NRT, i-Chantix akufuneki isetyenziswe kunye ne-nicotine ngenxa yomngcipheko wokunyuka kweziphumo ebezingalindelekanga. Utywala akufuneki busetyenziswe kunye neWellbutrin okanye iCantix.

U-Wellbutrin unokunxibelelana nezinye iziyobisi. I-Wellbutrin akufuneki isetyenziswe ngokudibeneyo ne-MAO inhibitors-ukusetyenziswa kwabo kufuneka kwahlulwe ngeentsuku ezili-14 ubuncinci. I-Wellbutrin inokuphinda isebenze kunye ne-anticonvulsants, i-antidepressants, i-antipsychotic, i-benzodiazepines, i-opioids, okanye i-beta blockers. Olunye unxibelelwano lweziyobisi lunokwenzeka. Nxibelelana nomboneleli wakho wezempilo uluhlu olupheleleyo lokudibana kwamachiza.

Iziyobisi	Iklasi yeziyobisi	Wellbutrin	Chantix
Inikotini	Unyango oluthatha indawo yeNicotine	Hayi	Ewe
Utywala	Utywala	Ewe	Ewe
ICarbamazepine I-Divalproex sodium IGabapentin ILamotrigine I-Oxcarbazepine IPhenobarbital IPhenytoin Ipiramidi ephezulu	IiAnticonvulsants	Ewe	Hayi
IClonazepam Diazepam ILorazepam	IiBenzodiazepines	Ewe	Hayi
Amitriptyline Citalopram Desipramine I-Desvenlafaxine Duloxetine I-Escitalopram	Ukudakumba	Ewe	Hayi
IPhenelzine I-Rasagiline Selegiline I-Tranylcypromine	I-MAO inhibitors	Ewe	Hayi
Ikhowudi Fentanyl IHydrocodone IHydromorphone Imethadone Imofini I-Tramadol	Iipioids	Ewe	Hayi
IHaloperidol IRisperidone Thioridazine	Iintsholongwane	Ewe	Hayi
Atenolol Imitha Ipropranolol	Ibhlokhi yeBeta	Ewe	Hayi
Clopidogrel	Antiplatelet	Ewe	Hayi
I-Digoxin	Iglycoside yentliziyo	Ewe	Hayi

Izilumkiso zeWellbutrin kunye neCantix

Izilumkiso ze-Wellbutrin:

I-Wellbutrin iza nesilumkiso sebhokisi emnyama (isilumkiso esomeleleyo njengoko kufunwa yi-FDA) yokuzibulala. Ukudakumba, okufana ne-bupropion, kunokunyusa umngcipheko wokucinga ngokuzibulala kunye nokuziphatha kwizigulana ezineminyaka engama-24 nangaphantsi. Izigulana kunye nabakhathaleli babo kufuneka babenolwazi ngalo naluphi na utshintsho kwiimvakalelo, ukubona izinto ezingekhoyo, iparanoa, inkohliso, umbono wokubulala, ubundlongondlongo, ubutshaba, ukuphazamiseka, ixhala, kunye / okanye ukothuka. Nasiphi na isigulana esithatha i-Wellbutrin, nokuba indala kangakanani na, kufuneka ijongwe ngononophelo kwezi mpawu.
Kukho umngcipheko we-mania okanye i-psychosis-umngcipheko uphezulu kwizigulana ezine-bipolar disorder.
I-Wellbutrin inokubangela ukuxhuzula. Umngcipheko unxulumene nedosi-idosi kufuneka inyuswe kancinci kwaye ayifanelanga ukudlula i-300 mg ngosuku. Ezinye iimeko zonyango zinokunyusa umngcipheko wokubanjwa. Nxibelelana nengcali yezempilo yakho ukufumana ulwazi oluthe kratya.
Ngenxa yokuba i-Wellbutrin inokubangela uxinzelelo lwegazi oluphezulu, uxinzelelo lwegazi kufuneka lubekwe esweni ngelixa uthatha i-Wellbutrin.
Abanye abaguli banokuba semngciphekweni we-glaucoma. Nxibelelana nengcali yakho yamehlo ukuze ufumane ulwazi oluthe kratya.
Isifo sikaStevens-Johnson sinokwenzeka. Esi sisenzo esibi, esisongela ubomi, ukusabela kolusu. Qhagamshelana nomboneleli wakho wezempilo ngokukhawuleza ukuba uhlakulela ukugqithisa kwesikhumba.

I-Wellbutrin ngokubanzi ayisetyenziswanga ekukhulelweni, kwaye kufuneka isetyenziswe kuphela ukuba isibonelelo esinokubakho siqinisekisa ubungozi obunokubakho kwimveku. Abatshayayo abakhulelweyo kufuneka bakhuthazwe ukuba bayeke ukutshaya ngeendlela zokuziphatha ngaphambi kokusebenzisa iWellbutrin. Nxibelelana ne-OB-GYN yakho malunga nengcebiso.

Izilumkiso zechantix:

I-Chantix inesilumkiso esibhokisiweyo malunga neziganeko ezinzulu ze-neuropsychiatric. Uxinzelelo, umbono wokuzibulala, ukuzama ukuzibulala, kunye nokuzibulala kugqityiwe kwizigulana ezithatha iChantix. Kuya kufuneka uyeke ukuthatha i-Chantix kwaye unxibelelane nomboneleli wakho wezempilo kwangoko ukuba ukhula, ubundlobongela, uxinzelelo lwengqondo, okanye utshintsho kwindlela yokuziphatha okanye ukucinga okungaqhelekanga, okanye ukuba uneengcinga zokuzibulala. Izigulana kwiChantix kufuneka zijongwe ngononophelo.
Kukho umngcipheko we-hypersensitivity okanye i-angioedema, kukudumba kobuso, umlomo, imiphetho kunye nentamo. Yeka i-Chantix kwaye ufune unyango olungxamisekileyo ukuba ezi mpawu zenzeka.
Njengo-Wellbutrin, isifo sikaStevens-Johnson sinokuqhagamshelana nomboneleli wakho wezempilo kwangoko ukuba uvela irhashalala.
Kunokubakho amathuba anyukayo kancinane kweziganeko zentliziyo-yazisa umboneleli wakho wezempilo ngeempawu ezintsha okanye eziba mandundu zesifo sentliziyo.
Sebenzisa ukuqhuba ngononophelo de ube uyazi ukuba ichantix ikuchaphazela njani. Ukulimala ngengozi kwenzeke ngenxa yokulala okanye isiyezi esivela kwiChantix.

I-Chantix inokubangela ingozi kwimveku xa isetyenziswe ngexesha lokukhulelwa, kwaye ngokubanzi ayifanele isetyenziswe. Kwizifundo zezilwanyana, uChantix wabangela ukunciphisa ubunzima bomntwana kunye nokunciphisa ukuzala kwinzala. Njengakwi-Wellbutrin, abantu abakhulelweyo abatshayayo kufuneka bakhuthazwe ukuba bayeke ukutshaya ngeendlela zokuziphatha.

Ngo-2016, i Kuxelwe i-FDA ukuba umngcipheko wempembelelo yezempilo yengqondo evela kuZyban kunye neChantix inokuba sezantsi kunokuba bekucingelwa ngaphambili kwaye izibonelelo zokuyeka ukutshaya zingaphezulu komngcipheko wokusebenzisa la mayeza. Nangona ingxelo ibhekisa kuZyban, iWellbutrin inento enye esebenzayo, ibupropion. Nokuba kunjalo, ulwazi ngamachiza lusenezilumkiso ezifanayo kwaye izigulana kufuneka zijongwe ngononophelo ngelixa uku-Wellbutrin okanye kwiChantix.

Imibuzo ebuzwa rhoqo malunga neWellbutrin vs Chantix

Yintoni iWellbutrin?

I-Wellbutrin yonyango lonyango oluchasayo olusetyenziswa ngaphandle kwelebheli (kunye okanye ngaphandle kwonyango lokutshintsha endaweni ye-nicotine) ukunceda abaguli bayeke ukutshaya.

Yintoni iCantix?

I-Chantix lunyango olusetyenziselwa ukunceda izigulana ziyeke ukutshaya.

Ngaba i-Wellbutrin kunye neCantix ziyafana?

Hayi, azifani. I-Wellbutrin yi-antidepressant enceda ukunciphisa iminqweno ye-nicotine, ngelixa i-Chantix isebenza ngokuthe ngqo kwii-nicotine receptors. Banolunye umahluko nabo, oluchazwe apha ngasentla.

Ngaba i-Wellbutrin okanye iCantix ibhetele?

Omabini la machiza ayasebenza ekuncedeni abaguli bayeke ukutshaya. Ukuba ufuna ukusebenzisa i-nicotine yonyango yokutshintsha endaweni yeyeza, i-Wellbutrin iya kuba lukhetho olungcono kuba ingathathwa kunye ne-NRT, kwaye i-Chantix akufuneki ithathwe kunye ne-NRT. Buza ugqirha wakho ukuba ngaba iWellbutrin okanye iCantix ingangcono kuwe.

Ngaba ndingayisebenzisa iWellbutrin okanye iCantix ngelixa ndikhulelwe?

Hayi. Ukuba ukhulelwe, nxibelelana nomboneleli wakho wezempilo. I-Wellbutrin kunye neChantix azisetyenziswa rhoqo kubafazi abakhulelweyo. Ukuba sele uthatha i-Wellbutrin okanye i-Chantix kwaye ufumanisa ukuba ukhulelwe, nxibelelana ne-OB-GYN yakho kwangoko ukuze ufumane isikhokelo.

Ndingayisebenzisa iWellbutrin okanye iCantix ngotywala?

Hayi. I-Wellbutrin enotywala inokunyusa umngcipheko wokubanjwa.

Yintoni ebhetele ukuyeka ukutshaya, iCantix okanye iWellbutrin?

Omabini la machiza ancede abaguli bayeke ukutshaya, kodwa kungcono ukuba uthethe nogqirha wakho kwaye uxoxe ukuba iChantix okanye iWellbutrin inokuba sisiyobisi esifanelekileyo kuwe, kuthathelwa ingqalelo imeko yakho, imbali kunye namanye amayeza owathathayo.

Kuthatha ixesha elingakanani ukuqala kweCantix?

Kungathatha iiveki ezimbalwa ukuba iChantix iqale ukusebenza. Ugqirha wakho unokukuxelela ukuba uthathe i-Chantix malunga neeveki ezili-12. Uya kuqala ngepakethi yenyanga yokuqala, emva koko uqhubeke nokuqhubeka kwenyanga. Emva kweeveki ezili-12, ugqirha wakho uya kuthatha isigqibo sokuba ufuna ukuthatha i-Chantix kwezinye iiveki ezili-12.

Uqala ngokukhawuleza kangakanani ukusebenza kakuhle kwi-Wellbutrin?

Kungathatha iiveki ezimbalwa ukuthatha i-Wellbutrin (kunye okanye ngaphandle kwe-NRT) de ubone umahluko. Dibana nogqirha wakho ukufumanisa ukuba kufuneka uthathe ixesha elingakanani ukuthatha i-Wellbutrin.