I-Lomotil vs.Imodium: Umahluko, ukufana, kwaye kukuphi okungcono kuwe

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I-Lomotil (diphenoxylate / atropine) kunye neImodium (loperamide) ngamayeza amabini alwa norhudo asetyenziselwa ukunyanga urhudo olungapheliyo . La mayeza asebenza ngeendlela ezifanayo zokunciphisa inani kunye nokuhamba rhoqo kwamathumbu. I-Lomotil kunye ne-Imodium ziyilelwe ukuba zithathwe xa kurhudo lwexesha elifutshane, elihlala lisombulula kwiintsuku ezimbalwa emva kokuthatha iyeza.

Kwiimeko ezininzi, urhudo, nangona lungamava angathandekiyo, ludla ngokuthamba kwaye luzimele. Unyango oluphambili kurhudo lubuyisela endaweni ulwelo kunye neelectrolyte ukuthintela ukomisa. Nangona kunjalo, amayeza afana neLomotil kunye neImodium anokuba luncedo kurhudo olunamandla kunye nesifo sorhudo esinganyangekiyo esinxulunyaniswa nesifo sengqondo esiswini (IBS).

Ngaphandle kokufana kwabo ekusebenziseni, iLomotil kunye neImodium zinomahluko wokukhumbula. Umzekelo, la mayeza aqukethe izinto ezahlukeneyo kwaye anezithintelo ezithile. Siza kuvavanya ukungafani kwabo kunye nokufana apha.

Yintoni umahluko ophambili phakathi kweLomotil kunye neImodium?

Lomotil

I-Lomotil sisiyobisi esinegama lophawu esinokufumaneka kuphela ngommiselo. Inomdibaniso we-diphenoxylate (i-opioid) kunye ne-atropine (ichiza le-anticholinergic).

I-Diphenoxylate sesona sithako siphambili sibophelela ii-opioid receptors emathunjini ukucothisa ukuhambisa kwamathumbu. I-Atropine yongezwa ukudimaza ukusetyenziswa gwenxa kweziyobisi kuba i-diphenoxylate yinto elawulwayo iyodwa.

Imodium

I-Imodium, ikwenziwe isitayile njenge-Imodium AD, ligama lophawu lweloperamide. Ngokungafaniyo neLomotil, iImodium inokuthengwa ekhawuntareni (OTC). Ke ngoko, ifumaneka ngokubanzi.

I-Loperamide yi-opioid eyenziweyo ebopha ii-opioid receptors eludongeni lwamathumbu ukucothisa ukuhamba kwamathumbu. Ikwathintela ikhemikhali ebizwa ngokuba yi-acetylcholine kwaye ikhokelela ekunciphiseni ukulahleka kolwelo kunye ne-electrolyte. Ngenxa yokuba i-Imodium ine-absorption encinci kwinkqubo ye-nervous system (CNS), ivelisa iziphumo ezincinci ze-CNS eziqhelekileyo eziqhelekileyo kwezinye i-opioids, kuquka i-diphenoxylate.

Umahluko ophambili phakathi kweLomotil kunye neImodium
	Lomotil	Imodium
Iklasi yeziyobisi	Unyango	Unyango
Uhlobo lweBrith / generic	Ibhranti kunye nohlobo oluqhelekileyo olukhoyo	Ibhranti kunye nohlobo oluqhelekileyo olukhoyo
Ngubani igama eliqhelekileyo?	Idiphenoxylate / Atropine	Loperamide
Zeziphi iifom eza nalo iziyobisi?	Ithebhulethi yomlomo Isisombululo samanzi	Ithebhulethi yomlomo Iifomsile zomlomo Ukumiswa kolwelo
Ithini idosi esemgangathweni?	Urhudo olunamandla: Amacwecwe ama-2 (2.5 mg diphenoxylate / 0.025 mg atropine) amaxesha amane yonke imihla kude kube kufikelelwe kulawulo lokuqala lohudo. Urhudo olunganyangekiyo: Ukunciphisa idosi yokuqala kwidosi yesondlo (ngesiqhelo iipilisi ezi-2 mihla le) njengoko kuyalelwa ngugqirha. Yeka ukuba iimpawu aziphuculanga kwiintsuku ezili-10.	Urhudo olunamandla: I-4 mg ekuqaleni, kunye ne-2 mg emva kwesitulo ngasinye esivulekileyo. Idosi ephezulu yemihla ngemihla: 16 mg Urhudo olunganyangekiyo: Sebenzisa idosi yesondlo ye-4 ukuya kwi-8 mg ngosuku. Yeka ukuba iimpawu aziphuculanga kwiintsuku ezili-10.
Lude kangakanani unyango oluqhelekileyo?	Urhudo lwexesha elifutshane olusombululayo kwiintsuku ezili-10. Ukusetyenziswa kwexesha elide kunokufuneka kwisifo sohudo esinganyangekiyo.	Urhudo lwexesha elifutshane olusombululayo kwiintsuku ezili-10. Ukusetyenziswa kwexesha elide kunokufuneka kwisifo sohudo esinganyangekiyo.
Ngubani oqhelekileyo usebenzisa amayeza?	Abantu abadala nabantwana abaneminyaka eli-13 ubudala nangaphezulu.	Abantu abadala nabantwana abaneminyaka emi-2 ubudala nangaphezulu. Abantwana abangaphantsi kweminyaka emi-6 kufuneka babonane nodokotela ngaphambi kokuba bathathe i-Imodium liquid.

Ngaba ufuna elona xabiso lilungileyo kwiLomotil?

Bhalisela izilumkiso zamaxabiso eLomotil kwaye ufumane ukuba amaxabiso atshintsha nini!

Fumana izilumkiso zamaxabiso

Imiqathango ephathwa nguLomotil kunye neImodium

I-Lomotil ivunyiwe yi-FDA njengonyango lokudambisa isifo sohudo. Oku kuthetha ukuba iLomotil icetyiswa njengonyango olongezelelweyo kunye neendlela zonyango eziphambili njengokuthintela ukomisa.

NjengoLomotil, i-Imodium ivunyiwe yi-FDA ukunyanga iintlobo ezininzi zorhudo. Imodium ingasetyenziselwa ukunyanga Urhudo lomhambi kunye nesifo sohudo esibangelwa ngamayeza afana ne-chemotherapy. I-Lomotil kunye ne-Imodium zinokunyanga isifo sohudo esinganyangekiyo esibangelwa sisifo sengqondo sesifo samathumbu (IBS).

Urhudo luchazwa njengokufumana isitulo esivulekileyo kathathu okanye nangaphezulu ngemini enye. Urhudo olubi ngokufuthi luhlala luthambile kwaye luhlala lungekho ngaphezulu kwentsuku enye okanye ezimbini. Ityhefu ekutyeni sesinye sezizathu eziqhelekileyo zorhudo olubi.

Urhudo olunganyangekiyo Inzima kakhulu kwaye inokuhlala ngaphezulu kweeveki ezine ngexesha. Iimpawu zorhudo zinokuhamba ngokwazo okanye zihlale ixesha elide, ezinokufuna unyango ngamayeza.

Imeko	Lomotil	Imodium
Urhudo olunamandla	Ewe	Ewe
Urhudo lomhambi	Ewe	Ewe
Urhudo olunganyangekiyo	Ewe	Ewe
Urhudo olunxulumene neChemotherapy	Ewe	Ewe

Ngaba iLomotil okanye iImodium isebenza ngakumbi?

I-Lomotil kunye ne-Imodium zezona zinto zixhaphakileyo ezisetyenziselwa ukubulala urhudo. Zombini ziyasebenza kwaye zisebenza ngokukhawuleza ukukhupha iimpawu zorhudo. Elona chiza lilungileyo kuwe liya kuxhomekeka kwimeko yakho iyonke, ekufuneka ihlolwe ngumboneleli wakho wezempilo.

Oko kwathiwa, i-Imodium ingaba yonyango elisebenzayo. Nangona kungekho zilingo zonyango ngokuthelekisa ngokuthe ngqo i-Lomotil kunye ne-Imodium, ezinye izifundo zibonisa ukuba i-Imodium lukhetho olukhethwayo lokunyanga isifo sohudo. Imfama ezimbini, Ukufunda crossover ifumanise ukuba i-loperamide ibiphezulu kune-diphenoxylate yokunyanga isifo sohudo nakwidosi esezantsi ephindwe kabini.
Enye Ukufunda crossover xa kuthelekiswa i-loperamide, i-diphenoxylate, kunye ne-codeine yokunyanga isifo sohudo esinganyangekiyo. Ngaphambi konyango, i-95% yabathathi-nxaxheba yafumana ukungxamiseka njengeyona mpawu iphambili kurhudo. Uphononongo lufumanise ukuba i-loperamide kunye ne-codeine bezisebenza ngakumbi kune-diphenoxylate yokufumana isiqabu. I-Diphenoxylate yafunyanwa ineziphumo ebezingalindelekanga ezininzi ngelixa i-loperamide iboniswa ukuba inezona zincinci.

Ukufunda kunye nokuthelekiswa kweendleko zeLomotil vs.Imodium

Uninzi lweMedicare Icandelo D kunye nezicwangciso zeinshurensi azigubungeli igama legama lomnwe. Nangona kunjalo, uninzi lwezicwangciso zeinshurensi zigubungela ingxelo yesiqhelo yeyeza. Izicwangciso ze-Medicare Icandelo D kufuneka zigubungele i-diphenoxylate / atropine kuxhomekeke kukugubungela. Ixabiso eliphakathi lentengiso ye-generic Lomotil ijikeleze i-38 yeedola. Jonga ikhemesti yakho ukuze ubone ukuba ungalisebenzisa na ikhadi lokonga ngesaphulelo. Amakhuphoni e-SingleCare Lomotil anokuhlisa iindleko ukuze uhlawule nge- $ 12.

I-Imodium sisiyobisi se-OTC esingenakugutyungelwa ngamayeza kunye nezicwangciso zeinshurensi. Ezinye izicwangciso zinokugubungela ifom yesiqhelo kunye nonyango. Kungcono ukujonga ifomula yesicwangciso sakho seinshurensi ukuze uqiniseke. Ixabiso eliphakathi le-loperamide lijikeleze i- $ 26. Ngesaphulelo se-SingleCare, unokufumana iipilisi ze-generic loperamide malunga ne- $ 14. Ukuze uthathe ithuba lokonga i-OTC, kuya kufuneka ufumane i- amayeza avela kugqirha wakho .

	Lomotil	Imodium
Ngokuqhelekileyo i-inshurensi?	Hayi	Hayi
Ngokuqhelekileyo igutyungelwe yiMedicare?	Hayi	Hayi
Umthamo osemgangathweni	2.5 mg diphenoxylate / 0.025 mg atropine, ubungakanani beetafile ezingama-30	2 mg, ubuninzi beepilisi ezingama-30
I-Medicare copay eqhelekileyo	$ 0- $ 150	$ 0- $ 99
Ixabiso elilodwa	$ 12	$ 14

Iziphumo eziqhelekileyo ezichaphazelekayo zeLomotil vs.Imodium

Iziphumo ebezingalindelekanga zeLomotil zibandakanya ukozela, ukuba nesiyezi, kunye nesicanucanu. Xa kuthelekiswa ne-Imodium, iLomotil inokuba neziphumo ebezingalindelekanga ze-CNS kubandakanya iintloko, ukungazinzi kunye nokudideka.

Iziphumo ebezingalindelekanga zixhaphake kakhulu ezinxulunyaniswa neImodium yile ukuqhina . Ezinye iziphumo ebezingalindelekanga eziqhelekileyo zibandakanya ukuba nesiyezi, isicaphucaphu, kunye nesisu okanye isisu.

Kwiidosi eziphezulu, iziphumo ebezingalindelekanga ezinzulu zeLomotil kunye neImodium zinokubandakanya ukozela okukhulu, ukubona izinto ezingekhoyo, kunye nokudinwa. Iziphumo ebezingalindelekanga ezimandundu njengokuphefumla okucothayo (uxinzelelo lokuphefumla) nazo zinokubakho ngeedosi eziyityhefu.

	Lomotil	Imodium
Imiphumela	Iyasebenza?	Rhoqo	Iyasebenza?	Rhoqo
Ukuqunjelwa	Hayi	-	Ewe	5.3%
Ukuba nesiyezi	Ewe	* akuxelwa	Ewe	1.4%
Isicaphucaphu	Ewe	*	Ewe	1.8%
Iintlanzi zesisu	Ewe	*	Ewe	1.4%
Ukuhlanza	Ewe	*	Ewe	*
Umlomo owomileyo	Ewe	*	Ewe	*
Ukozela	Ewe	*	Ewe	*
Intloko ebuhlungu	Ewe	*	Hayi	-
Ukungazinzi	Ewe	*	Hayi	-
Ukudideka	Ewe	*	Hayi	-

Olu alunakuba luluhlu olupheleleyo lweziphumo ezibi ezinokwenzeka. Nceda ujonge ugqirha wakho okanye umboneleli wezempilo ukuze ufunde okungakumbi.
Umthombo: DailyMed ( Lomotil ), Yonke imihla ( Imodium )

Ukudibana kweziyobisi kweLomotil vs.Imodium

I-Lomotil inokusebenzisana neziyobisi ezifana ne-monoamine oxidase inhibitors (MAOIs) kunye ne-CNS depressants. Ukuthatha i-MAOI, njenge-selegiline okanye i-phenelzine, kunye neLomotil kunokunyusa umngcipheko weengxaki zoxinzelelo lwegazi, okanye uxinzelelo lwegazi oluyingozi. Umngcipheko weziphumo ezibi unokunyuswa ngelixa uthatha amayeza oxinzelelo lwe-CNS njengeebarbiturates, benzodiazepines, kunye izihlunu eziphumlayo .

Ngokungafaniyo neLomotil, i-Imodium icutshungulwa kakhulu kwisibindi zii-enzyme ezinje nge-CYP3A4 enzyme kunye ne-CYP2C8 enzyme. Iziyobisi ezithintela, okanye ezivimba, ezi enzymes zinokunyusa amanqanaba eImodium egazini. Ngenxa yoko, ukuthatha la machiza kunye kunokunyusa umngcipheko weziphumo ebezingalindelekanga.

Iziyobisi	Iklasi yeziyobisi	Lomotil	Imodium
Selegiline IPhenelzine Isocarboxazid I-Tranylcypromine	I-Monoamine oxidase inhibitors (MAOIs)	Ewe	Hayi
IPhenobarbital IPentobarbital IAlprazolam ILorazepam I-Trazodone Oxycodone	Uxinzelelo lwe-CNS	Ewe	Ewe
Saquinavir Itraconazole	CYP3A4 inhibitors	Hayi	Ewe
Gemfibrozil	CYP2C8 inhibitors	Hayi	Ewe
Iquinidine Ritonavir	I-P-glycoprotein inhibitors	Hayi	Ewe

Olu ayilo luhlu lupheleleyo lokunxibelelana kweziyobisi. Nceda uqhagamshelane nogqirha wakho ngaphambi kokuba uthathe la mayeza.

Izilumkiso zeLomotil kunye neImodium

I-Lomotil akufuneki isetyenziswe kubantwana abangaphantsi kweminyaka emi-6 ngenxa yomngcipheko okhulayo wokuphefumla kunye noxinzelelo lwe-CNS. Abo bane-jaundice yokuthintela okanye i-hypersensitivity eyaziwayo kwi-diphenoxylate okanye i-atropine kufuneka bakuphephe ukusebenzisa iLomotil.

I-Imodium ixelwe ukuba ibange IiTorsades de Pointes , ukubanjwa kwentliziyo, kunye nokufa xa kuthathwe ngaphezulu kuneedosi ezicetyiswayo. Kucetyiswa ukuba uthathe kuphela idosi encinci efunekayo njengoko kuyalelwe ngumboneleli wakho wezempilo. I-Imodium akufuneki isetyenziswe kubantwana abancinci nakwiintsana ezingaphantsi kweminyaka emi-2 ubudala ngenxa yomngcipheko wokuphefumla kunye noxinzelelo lwe-CNS.

I-Lomotil kunye ne-Imodium akufuneki zisetyenziselwe ukunyanga isifo sorhudo esibangelwe zizifo ezibangelwa ziintsholongwane. La machiza akufuneki asetyenziselwe ukunyanga urhudo olubangelwa zizinto ezinje nge IClostridium difficile kwaye Salmonella .

Dibana nogqirha wakho ukuba unayo nayiphi na imeko yonyango ngaphambi kokuba uthathe la mayeza. Kuyacetyiswa ukuba uthathe la mayeza ngengcebiso yezonyango evela kumboneleli wakho wezempilo.

Imibuzo ebuzwa rhoqo malunga neLomotil vs.Imodium

Yintoni iLomotil?

I-Lomotil sisiyobisi esisetyenziswa njengonyango lokuhambisa urhudo. I-Lomotil iyafumaneka ngegama lophawu kunye neenguqulelo eziqhelekileyo. Ingathathwa kwisifo sohudo esiqatha okanye esingapheliyo kubantu abadala kunye nabantwana abaneminyaka eli-13 ubudala nangaphezulu.

Yintoni i-Imodium?

I-Imodium sisiyobisi esingaphaya kwekhawuntare (OTC) esivunyiweyo yi-FDA ukunyanga isifo sorhudo. I-Imodium isetyenziselwa ukunyanga utyatyazo loMhambi nangona ingaphinde inyange isifo sohudo esinganyangekiyo esibangelwa yi-IBS. I-Imodium inokunyanga abantu abadala kunye nabantwana abaneminyaka emi-2 ubudala nangaphezulu.

Ngaba iLomotil kunye neImodium ziyafana?

Hayi. I-Lomotil kunye ne-Imodium azifani. Nangona besebenza ngeendlela ezifanayo, iLomotil inokufunyanwa kuphela ngugqirha. Imodium inokuthengwa ekhawuntarini.

Ngaba iLomotil okanye iImodium ibhetele?

I-Lomotil kunye ne-Imodium zombini ziziyobisi ezisebenzayo zokunyanga isifo sohudo. Abanye uphando ibonakalisile ukuba akukho mahluko ubonakalayo ekusebenzeni phakathi kwezi zimbini. Nangona kunjalo, enye izifundo zibonise ukuba i-Imodium iyasebenza ngakumbi kwaye inyamezeleke ngcono. Dibana nogqirha wakho ukuze ufumane olona nyango lulungileyo olulungele wena.

Ndingayisebenzisa i-Lomotil okanye i-Imodium ngelixa ndikhulelwe?

Abanye oogqirha banokuvumela ukusetyenziswa kweLomotil okanye i-Imodium ngexesha lokukhulelwa kuphela xa kukho imfuneko. Ngaphandle koko, iLomotil kunye neImodium azikhuthazwa ngokubanzi ngexesha lokukhulelwa ngenxa yokonzakala kosana olungekazalwa. Thetha nogqirha wakho malunga nokukhetha ukungahambi kakuhle kwesisu xa ukhulelwe.

Ndingayisebenzisa i-Lomotil okanye i-Imodium ngotywala?

Akukhuthazwa ukusela utywala ngelixa usebenzisa iLomotil okanye i-Imodium. I-Lomotil kunye ne-Imodium zinokubangela iziphumo ezibi njengokuwozela kunye nesiyezi. Ukusela utywala kunokuzonyusa ezi ziphumo bezingalindelekanga.

Kutheni iLomotil ivaliwe?

ILomotil ayisosisiyobisi singavunyelwanga. Nangona kunjalo, yiShedyuli V into elawulwayo njengoko ihlelwe yi-DEA. Oku kuthetha ukuba kunokubakho ukusetyenziswa gwenxa kunye nokusetyenziswa gwenxa xa usebenzisa eli chiza. Iyodwa, idiphenoxylate, eyona nto iphambili esebenzayo yeLomotil, sisixhobo seShedyuli II esinamandla okuphathwa gadalala.

Ungamthatha uLomotil ixesha elide?

I-Lomotil ayikhuthazwa ukuba isetyenziselwe ngaphezulu kweentsuku ezili-10 Uhudo olubi. Kwezinye iimeko, iLomotil ingasetyenziselwa ukusetyenziswa kwexesha elide, ngakumbi kwi-diarrhea engapheliyo. Ukusetyenziswa kwexesha elide kweLomotil kufuneka kubekwe esweni ngugqirha.

Kwenzeka ntoni ukuba i-Imodium ayiyeki urhudo?

Imodium kufuneka ikhuphe iimpawu zorhudo oluncinci ngaphakathi kweeyure ezingama-48. Ukuba ufumana oku kulandelayo, kufuneka ubize ugqirha wakho ngokukhawuleza:

• Igazi esitulweni
• Umkhuhlane okanye ubushushu obungaphezulu ko-101.3 ° F
• Intlungu ebuhlungu esiswini
• Ukugqithisa izitulo ezintandathu okanye nangaphezulu ngosuku
• Urhudo oluhlala ngaphezulu kweeyure ezingama-48
• Iimpawu ezinje ngobunzima bokukhanya, ukudideka, iintlungu zesifuba, okanye ukubola