Yintoni omele uyazi malunga ne-migraine
Imfundo yezeMpilo Usokhemesti wazi kakuhleKusenokwenzeka ukuba wena okanye umntu ohlala naye ngemigraine. Inyaniso, 1 kwa-4 Amakhaya aseMelika aquka umntu one-migraine. Sisifo sesithathu esixhaphakileyo ehlabathini. Uqikelelo lweAmerican Migraine Foundation ukuba iindleko zonyaka zomsebenzi ophosiweyo kunye neendleko zonyango ezichanekileyo ezinxulumene ne-migraine zifikelela kwi-20 yezigidi zeedola.
UJuni nguNyanga weSizwe we-Migraine kunye neNyanga yokuQatshelwa kweNtloko, eli lixesha labanikezeli bezempilo kunye nezigulana zokuthetha ngokuqondwa kunye nonyango lwe-migraine. Nantsi into ekufuneka uyazi ngumahluko phakathi kwe-migraine kunye neentloko, xa ufuna unyango, kwaye loluphi ukhetho lwakho lonyango.
Imigraine ngokuchasene nentloko: Uyintoni umahluko?
Iindidi zentloko
Isiqhelo esiqhelekileyo, okanye esinga-migraine, intloko ebuhlungu inemvelaphi emininzi. Olunye udidi oluqhelekileyo intloko ebuhlungu . Intloko yentloko yintlungu ebuthathaka, engapheliyo, engabambisiyo enxulunyaniswa nokuqina kwesikhumba. Olu hlobo lwentloko lubangelwa kukudakumba ngokweemvakalelo okanye ngamanye amaxesha kunxulumene nokudakumba.
Intloko yesono inxulunyaniswa neempawu zokungabikho komzimba kunye neempawu zokuxinana ezikhokelela kwintlungu esemva kwamehlo kunye nesisu somqala ngenxa yoxinzelelo olwakhiweyo. Olu hlobo lwentloko lunokuchazwa ngakumbi kusasa okanye xa isigulana sigobile ngenxa yokutshintsha koxinzelelo.
Iintloko zentloko ezisebenzisanayo inokuba buhlungu kakhulu kwaye ixhaphake kakhulu emadodeni. Intlungu ikummandla wamehlo, kwaye inokuba bukhali kakhulu, ihlale iiyure, kwaye yenzeke mihla le. Ezi ntloko zingabangelwa ziziselo ezinxilisayo kunye nokutshaya.
Zininzi ezinye iintlobo zentloko . Ezinye zinokunxulunyaniswa notshintsho lwehomoni okanye imijikelo yokuya exesheni. Ezinye zinokunxulunyaniswa necaffeine okanye ukurhoxiswa kwenicotine. Ukulamba okanye ukuzila ukutya kunokubangela iintloko. Imisebenzi ebangela i-eyestrain, njengemidlalo yevidiyo okanye ukusebenzisa ikhompyuter, inokuthi ikhokelele kwintloko engeyiyo-migraine.
Kodwa akukho nanye kwezi ntloko ifana ne migraine . Imigraine yahlukile. Ngapha koko, iintlungu entlokweni yakho luphawu olunye lwe-migraine. Ngokwenyani unokuba ne-migraine ngaphandle kwentlungu entlokweni yakho ehambelana nayo. Ke, ungazi njani ukuba une-migraine?
Iimpawu zeMigraine
Iimpawu ezihambelana nokuhlaselwa kwe-migraine zi:
- Intlungu ebuhlungu, ihlala kwicala elinye
- Ukukhanya kunye / okanye uvakalelo lwesandi
- Isihlunu kunye / okanye ukugabha
- Siza Kubane
- Umbono utshintsha, ukungaboni kakuhle, okanye iindawo ezingaboniyo
Uninzi lwezi mpawu luyazichaza, ngaphandle kwe-aura. I-aura ehambelana neziqendu ze-migraine yinguqu yoluvo eyenzeka ngaphambi kokuqala kwemigraine. Ingabandakanya ukubona ukukhanya kokukhanya okanye imvakalelo yokutswina kwimida yakho. Isenokuqhubeka iyure enye. Ayizizo zonke i-migraine ezinxulumene ne-aura. Izigulana eziye zafumana i-aura ngekhe zibenamava ngayo yonke imigraine.
Akunyanzelekanga ukuba ube nazo zonke ezi mpawu zingasentla kwangoko ukuze ufumaneke une-migraine. Zonke iintloko kunye nesigulana sahlukile.
Ukuhamba rhoqo kwesi sigulana xa kuhlaselwa i-migraine kubaluleke kakhulu ukuba sikuqonde. Imigraines yeepisodic ezisezantsi kakhulu zezi zenzeka ngaphantsi kwamaxesha ali-10 ngenyanga. Imigraines ye-episodic ephezulu yenzeka rhoqo ngamaxesha ali-10 ukuya kwezi-14 ngenyanga. Imigraines engapheliyo ichazwa njengamaxesha ali-15 okanye nangaphezulu ngenyanga.
Ukuba awuqinisekanga malunga nokuba uluhlobo luni lwentloko ojamelana nayo, okanye ukuba intloko yakho iqhubekile kwaye kunzima ukuyikhulula, umboneleli wakho wezempilo uya kuba nakho ukufumanisa ngokuchanekileyo intloko yakho okanye i-migraine, kunye nokwenza iingcebiso ezifanelekileyo zonyango.
Ukhetho lonyango lwe-Migraine
Kukho zombini amayeza kunye neyeza-counter-counter ongayithatha ukuphatha i-migraine. Nantsi into enokubonelelwa ngumboneleli wakho wezempilo.
Amayeza e-migraine angaphezulu kwe-counter
I-Acetaminophen kunye ne-nonsteroidal anti-inflammatories (i-NSAID), ezinje nge-aspirin, ibuprofen, okanye naproxen, inokuthathwa ngexesha elifutshane ukubonelela ngemigraine. Olu unyango alubizi kwaye lunokunceda kwithamo elinye okanye ezimbini. I-caffeine, i-vasoconstrictor, nayo iyasebenza ekupheliseni iintlungu ze-migraine. I-Excedrin Migraine, ukhetho olukhethiweyo lwe-OTC, yimveliso yokudibanisa equlathe i-acetaminophen, i-aspirin kunye ne-caffeine. Usokhemesti wakho angakukhomba kwicala elifanelekileyo lokufumana iintlungu xa ungaqinisekanga.
Ngawo onke la mayeza, kubalulekile ukuba uqaphele ukuba unyango lwe-counter-counter alwenzelwanga ukusetyenziswa kwexesha elide ngaphandle kokukhokelwa ngokuthe ngqo ngumboneleli wakho wezempilo.
| Unyango lwe-migraine engaphezulu kwe-counter | |||
|---|---|---|---|
| Igama leziyobisi | Ukwahlulahlula | Umlinganiselo oqhelekileyo | Elona xabiso liLodwa lokuKhathalela |
| I-Aspirin | NSAID | I-325 mg ukuya kwi-1000 mg qho kwiiyure ezi-4 ukuya kwezi-6 | I $ 1.69 |
| Ibuprofen | NSAID | 200 mg ukuya ku-400 mg qho kwiiyure ezi-4 ukuya kwezi-6 | $ 6.06 |
| INaproxen | NSAID | 220 mg qho kwiiyure ezili-12 | $ 4.31 |
| Excedrin Migraine | NSAID | (Acetaminophen 250 mg / Aspirin 250 mg / Caffeine 65 mg) 1 ukuya 2 amacwecwe rhoqo kwiiyure ezi-6 | $ 2.40 |
Amayeza amayeza e-migraine
Ngelishwa, iinketho ze-OTC aziboneleli ngoncedo olwaneleyo lwe-migraine. Kwezo meko, amayeza kagqirha angenza umohluko. Imigqaliselo ye-migraine iwela kwiindidi ezimbini: ezo zisetyenziselwa unyango kunye nezo zisetyenziselwa ukuthintela.
Unyango lwe-Migraine
Isikhokelo sonyango esenziwe ngugqirha Uluhlu lwee-NSAID (ngakumbi, ibuprofen kunye ne-naproxen) njengonyango lodidi lokuqala lwe-migraine ebukhali ukuya kumodareyitha. Ii-NSAID zikhulula iintlungu ngokunciphisa ukukhutshwa kwe-prostaglandins yokuvuvukala. Olu lukhetho olunokubiza iindleko olusebenzayo kwimigraines ethambileyo ukuya kumodareyitha. Ii-NSAID ngokubanzi zigutyungelwe ngorhwebo okanye ngezicwangciso zeinshurensi yecandelo le-Medicare Part D. Qiniseka ukuba ujonga i-SingleCare yolondolozo lweendleko ngokunjalo. Umzekelo, amayeza aqhelekileyo e-ibuprofen 800 mg anokuxabisa ama- $ 37 ngaphandle kwe-inshurensi, kodwa nge Ikhuphoni elilodwa , lo myalelo ungaphantsi kwe- $ 6. Ii-NSAIDs akufuneki zithathwe kwisisu esingenalutho, kwaye nokuba ngugqirha, zisenokungabi ngcono ekusetyenzisweni okungaguqukiyo, kwexesha elide.
Ukumodareyitha ukuya kwi-migraines ebukhali, ii-agonists ze-5HT, ezaziwa njenge-triptans, lunyango lokuqala. I-Triptans ivuselela i-serotonin kwingqondo, eyehlisa ukudumba kwaye ibangele i-vasoconstriction. I-Vasoconstriction idlala indima ebalulekileyo kulawulo lwe-migraine njengoko ilawula uvakalelo lokuhamba kwegazi. Oku kunceda ukulawula ukubetha okanye ukuziva ngathi amava amaninzi ngexesha lokuhlaselwa kwe-migraine.
Kukho ukhetho oluninzi lweziyobisi ze-triptan ezikhoyo kwintengiso, kubandakanya: almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, kunye ne-zolmitriptan. Ummeli wakho uya kuthatha isigqibo sokuba yeyiphi eyona nto ingakulungela, kodwa zonke ziye zafakazelwa zisebenza kakuhle ekuphatheni i-migraine. Ii-Triptans nazo zihlala zigutyungelwe yi-inshurensi, nangona ezinye izicwangciso zinokuba nokusikelwa umda kuluhlobo luni lwe-triptan abagubungela ngayo okanye ubungakanani bayo. Ixabiso elingaphandle kwepokotho le-sumatriptan linokuya kwi-200 yeedola kwiipilisi nje ezili-9, kodwa Ukhathalelo izisa elo xabiso phantsi kweedola ezili-13.
| Unyango lwe-migraine yonyango | |||
|---|---|---|---|
| Igama leziyobisi | Ukwahlulahlula | Umlinganiselo oqhelekileyo | Elona xabiso liLodwa lokuKhathalela |
| Ibuprofen | NSAID | 600 mg qho kwiiyure ezi-6 | $ 6.06 |
| INaproxen | NSAID | 500 mg qho kwiiyure ezili-12 | $ 4.31 |
| IAlmotriptan | I-5HT agonists (ii-triptans) | 6.25 mg - 12.5 mg ekuqaleni, inokuphinda kanye kwiiyure ezimbini ukuba akukho kuphumla. | n / A |
| Eletriptan | I-5HT agonists (ii-triptans) | I-20 mg ukuya kwi-40 mg ekuqaleni, inokuphinda kanye kwiiyure ezimbini ukuba akukho kuphumla. | $ 161.04 |
| Frovatriptan | I-5HT agonists (ii-triptans) | I-2.5 mg ekuqaleni, inokuphinda kanye kwiiyure ezimbini ukuba akukho sibonelelo. | $ 112.56 |
| INaratriptan | I-5HT agonists (ii-triptans) | 1 mg ukuya ku-2.5 mg ekuqaleni, unokuphinda kanye kwiiyure ezi-2 ukuba akukho isiqabu. | $ 92.61 |
| Rizatriptan | I-5HT agonists (ii-triptans) | I-5 mg ukuya kwi-10 mg ekuqaleni, inokuphinda kanye kwiiyure ezimbini ukuba akukho kuphumla. | $ 43.83 |
| ISumatriptan | I-5HT agonists (ii-triptans) | I-25 mg ukuya kwi-50 mg ekuqaleni, inokuphinda kanye kwiiyure ezimbini ukuba akukho kuphumla. | Iidola ezingama-42.90 |
| Zolmitriptan | I-5HT agonists (ii-triptans) | I-2.5 mg ukuya kwi-5 mg ekuqaleni, inokuphinda kanye kwiiyure ezimbini ukuba akukho kuphumla. | $ 37.97 |
Uthintelo lwe-Migraine
Izinketho zokuthintela zidlala indima ebalulekileyo kunyango lwezigulana ezine-migraine engapheliyo. Ezi zigulana zisafuna ukufikelela kunyango olunzima xa kusenzeka i-migraines, kodwa amayeza othintelo anokunciphisa ukuba zenzeka kangaphi ezi migraine. Kude kube kutshanje, iBotox, okanye i-onabotulinumtoxin A, yayikukuphela konyango lokuthintela olwamkelweyo yi-FDA. Ngelixa lisebenza kakhulu, iBotox kunokuba nzima ukuba yamkelwe phantsi kweinshurensi kwaye inokubiza kakhulu. Iminyaka, ezinye iiklasi ezininzi zamayeza bezisetyenziswa off-ileyibheli kuthintelo lwe-migraine ngempumelelo enkulu. Oku kubandakanya amayeza okuthatha, amayeza okulwa uxinzelelo, kunye noxinzelelo lwegazi. La mayeza ngokubanzi ane-inshurensi elungileyo kwaye aneendleko-ezichanekileyo iindlela zokunceda ukuthintela i-migraine engapheliyo. Le tshathi ilandelayo inika isishwankathelo sokhetho olufumanekayo kwiklasi nganye, nangona kungenakwenziwa ukuba kubandakanywe konke.
| Amayeza asetyenziswa rhoqo kuthintelo lwe-migraine | |||
|---|---|---|---|
| Igama leziyobisi | Ukwahlulahlula | Umlinganiselo oqhelekileyo | Elona xabiso liLodwa lokuKhathalela |
| Ukwahlula | I-Anticonvulsant | 500 mg ER kabini yonke imihla | $ 12.99 |
| Ipiramidi ephezulu | I-Anticonvulsant | 25 mg kabini yonke imihla | $ 8.53 |
| Imitha | IBeta-blocker | 25 mg kabini yonke imihla | $ 4 |
| Ipropranolol | IBeta-blocker | 20 mg kabini yonke imihla | $ 16.33 |
| Amitriptyline | I-Tricyclic yoxinzelelo | 25 mg ngexesha lokulala | $ 4 |
| IVenlafaxine | Ukukhetha i-Norepinephrine Reuptake Inhibitor (Antidepressant) | I-150 mg ER kanye yonke imihla | $ 15 |
Kutshanje, iklasi entsha yamachiza ephuhliselwe uthintelo lwe-migraine yeza kwintengiso. Eli liqela le-calcitonin enxulumene ne-peptide (CGRP) inhibitors. Izigulana ezinama-migraines zaziwa ngokuba namanqanaba aphezulu e-CGRP. Xa ibophelela kwi-receptor yayo, iqala i-cascade yeziganeko ezikhokelela kukudumba kunye nentlungu ye-migraine. Abantu abane-migraine engapheliyo banokuba nenani leentsuku ze-migraine ezinqunywe kwisiqingatha kunye ne-CGRP inhibitors.
La mayeza anokubiza kakhulu kwaye i-inshurensi yokugubungela inokwahluka kakhulu. Abavelisi banikezela ngeenkqubo zokonga, kwaye i-SingleCare ihlala ifumaneka ukukunceda ufumane elona xabiso liphezulu. Le tshathi ilandelayo inika isishwankathelo sento ekhoyo ngoku kule klasi.
| Unyango lwe-anti-CGRP migraine | ||
|---|---|---|
| Igama lebrand | Igama lesiqhelo | Ukwahlulahlula |
| UAimovig | I-erenumab-aooe | I-CGRP Monoclonal Antibodies |
| Uhambo | mzantsiweb | |
| Ubungqongqo | Ndiyifumanisa-gnlm | |
| Vyepti | Uyilelo-jjmr | |
| Ubrelvy | ubrogepant | I-CGRP yeMolecule Receptor Antagonists |
| Ukukhulisa i-ODT | i-rimegepant sulfate |
Olu luhlu alwenzelwanga ukuba lubandakanye konke kwaye unyango alunakulunga kuye wonke umntu one-migraine. Kuhlala kukulungele ukuthetha nomboneleli wakho wezempilo ukuze uncede uthathe isigqibo sonyango lwakho olulungileyo. Unokuthelekisa Unyango oluninzi lwe-migraine apha .
